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Monkeypox may not mutate as fast as coronaviruses, but that doesn’t mean it can’t adapt to its new hosts
Published: June 24, 2022 11.37am EDT
Connor Bamford
Research Fellow, Virology, Queen's University Belfast
...
In general, large DNA viruses such as monkeypox are no different from other viruses, and their mutability is the basis for our ability to track and trace monkeypox outbreaks. They make mistakes and errors accumulate, which can be used as fuel for evolution and biological changes. There’s even evidence from the recent monkeypox outbreak that the host cell is directly mutating the virus genome.
Studies focusing on related poxviruses like the vaccinia virus have even uncovered new tricks they can use, which include rapidly amplifying the number of genes they use to attack our immune system. They could even borrow some of our own genes to help them infect us.
We can’t predict the trajectory that monkeypox evolution will take, so we must take the threat of this virus adapting to its new hosts (humans) seriously. And we need to use all the public health tools at our disposal to halt the current outbreak in all countries – including those where it is endemic.
...
https://theconversation.com/monkeypo...w-hosts-183855
Monkeypox may not mutate as fast as coronaviruses, but that doesn’t mean it can’t adapt to its new hosts
Published: June 24, 2022 11.37am EDT
Connor Bamford
Research Fellow, Virology, Queen's University Belfast
...
In general, large DNA viruses such as monkeypox are no different from other viruses, and their mutability is the basis for our ability to track and trace monkeypox outbreaks. They make mistakes and errors accumulate, which can be used as fuel for evolution and biological changes. There’s even evidence from the recent monkeypox outbreak that the host cell is directly mutating the virus genome.
Studies focusing on related poxviruses like the vaccinia virus have even uncovered new tricks they can use, which include rapidly amplifying the number of genes they use to attack our immune system. They could even borrow some of our own genes to help them infect us.
We can’t predict the trajectory that monkeypox evolution will take, so we must take the threat of this virus adapting to its new hosts (humans) seriously. And we need to use all the public health tools at our disposal to halt the current outbreak in all countries – including those where it is endemic.
...
https://theconversation.com/monkeypo...w-hosts-183855