It has been known for YEARS be highly antibacterial for wounds and all illnesss.Anyone know anything about Manuka honey?
View: https://twitter.com/wtf_america1776/status/1612675449166987265?s=46&t=Zie6cxGBzvwKBFLoQ5G-GA
Oopsie.The hajj also involves close contact in large crowds, which in 2015 saw over 2,400 people killed in a crush and stampede.
Thanks for this info. Appreciate itA few comments were made requesting info on the hydrogen peroxide nasal rinse. This article has that and much more info in it.
When reading it, I flash back to when they made fun of Trump for wondering if there was a way to get common disinfectants into the body to kill the virus. He was ahead of his time...
ETA: I put a link for the Betadine mouth wash in the article where it is discussed. Amazon is running a promotion right now, so if you order it now, and you order 2, you get one half off so the total price is around $16 for the 2.
(fair use applies)
Is Nasal Irrigation More Important Than Hand-Washing?
Analysis by Dr. Joseph Mercola
January 10, 2023
- Flushing your sinuses may be an effective way to inhibit the progression of a virus such as SARS-CoV-2 by lowering the viral load in your sinuses
- Research has demonstrated that nasal irrigation reduces the symptoms and duration of viral illnesses such as the seasonal flu and common cold
- Nasal irrigation and gargling with hypertonic saline has been shown to reduce the duration of the common cold by 1.9 days and reduce transmission within the household by 35% by reducing viral shedding when done within 48 hours of symptom onset
- You may also be able to reduce the risk of SARS-CoV-2 migrating into your lungs by gargling a saline solution or using a povidone-iodine solution such as Betadine Sore Throat Gargle
- Nebulizing hydrogen peroxide or colloidal silver may be even more effective. A recent review found 0.5% hydrogen peroxide effectively inactivated a range of human coronaviruses, including those responsible for SARS and MERS, within one minute of exposure
By now, you probably understand the importance of hand-washing to prevent the spread of infectious illness. But did you know flushing your sinuses might be an even better way to inhibit the progression of a viral illness such as COVID-19? In an April 20, 2020, article, Best Life features the recommendations of Dr. Amy Baxter, a pediatric emergency medicine physician in Atlanta, Georgia.
Nasal irrigation, she says, is a rarely discussed strategy that can help reduce the progression of illness in those who have tested positive for COVID-19 infection. In an April 2, 2020, response to a BMJ paper about the lack of personal protection equipment on COVID-19 frontlines, professor Robert Matthews also brought up the importance and potential usefulness of oropharyngeal washing to protect health care workers from infection. As reported by Best Life:
“Nasal irrigation, or a nasal wash, has long been considered an effective way to remove viruses or bacteria from sinus cavities.
According to Baxter, recent clinical trials show that nasal irrigation reduces the duration and symptoms for other viral illnesses like flu and the common cold, though it hasn't yet been studied for COVID-19. Still, she has multiple reasons for believing that this approach can be effective in preventing coronavirus from worsening in a sick patient.”
Why Nasal Irrigation?
As noted by Baxter, researchers have found that the viral load of SARS-CoV-2 tends to be heaviest in the sinuses and nasal cavity. Regularly rinsing your sinuses therefore makes sense since it would help clear out the pathogen and prevent it from gaining a strong foothold and migrating into your lungs.
The age and gender discrepancies observed in COVID-19 also supports nasal irrigation. Children are at virtually no risk from COVID-19, while death rates among the elderly are at their highest. More men than women also die from the infection.
“Children don't develop full sinuses until teens; males have larger cavities than women, and the cavities are largest [in those] over 70 years,” Baxter notes.
Research has previously demonstrated that nasal irrigation reduces the symptoms and duration of other viral illnesses such as the seasonal flu and common cold.
In one randomized controlled trial,4 nasal irrigation and gargling with hypertonic saline were found to reduce the duration of the common cold by 1.9 days and reduce transmission within the household by 35% by reducing viral shedding when done within 48 hours of symptom onset.
While it has not yet been studied as a preventive method for COVID-19 specifically, there’s reason to suspect nasal irrigation might be helpful.
Baxter points out that COVID-19 death rates in Southeast Asian countries such as Thailand, Vietnam and Laos have been surprisingly low, and nasal irrigation is common practice in those areas. According to Baxter, some 80% of the Southeast Asian population do it.
How to Irrigate Your Sinuses
Baxter suggests irrigating your sinuses any time you’ve been exposed to an infected individual or test positive for COVID-19. She recommends flushing your sinuses in the morning using a mixture of boiled lukewarm water (8 ounces) and povidone-iodine (half a teaspoon).
Povidone-iodine has been shown to effectively kill not only Klebsiella pneumoniae and Streptococcus pneumoniae bacteria, but to also rapidly inactivate SARS-CoV, MERS-CoV, H1N1 influenza virus A and rotavirus after 15 seconds of exposure.5
The mixture used in this study: 7% povidone-iodine diluted 1-to-30, which equates to a total concentration of 0.23% povidone-iodine, inactivated over 99% of the coronaviruses causing SARS and MERS.
Either a neti pot or NeilMed sinus rinse bottle can be used. The water pressure you get from a sinus rinse bottle can provide a more effective flush. If higher pressure is uncomfortable, a neti pot, which relies on gravity, may be a more comfortable choice. In the evening, Baxter recommends flushing your sinuses again with a mixture of:
8 ounces of boiled lukewarm water
0.5 teaspoon baking soda
1 teaspoon table salt
Gargling May Also Be Helpful
You may also be able to reduce the risk of SARS-CoV-2 migrating into your lungs by gargling. As noted by Dr. Neal Naito in a March 29, 2020, New York Times article,6 while there’s “no firm proof” that gargling can prevent COVID-19, there are virtually no downsides to the advice.
Like Baxter, Naito points out that many East Asian countries such as Japan see gargling as a commonsense hygiene practice.
“In East Asia, particularly in Japan, gargling is strongly encouraged by the national government, along with other practices like hand-washing, wearing face masks and social distancing, as a matter of routine hygiene during the regular cold and flu season.
(Not everyone, though, can gargle effectively, including some people with neck pain, stroke or dementia, as well as children generally under the age of 8.) Most of the early studies suggesting that gargling may help to prevent and treat upper and lower respiratory infections, not surprisingly, come from Japan,” Naito writes.
An over-the-counter povidone-iodine oral gargle solution, used for decades by the Japanese for the treatment of sore throat, appears most useful. One small study from Japan, published in 2002, found patients diagnosed with chronic respiratory disease who gargled with a povidone-iodine solution at least four times a day reduced their incidence of acute respiratory infection by about 50%.
Do Not Use Iodine-Based Skin Disinfectant for Gargling
Importantly, Naito stresses that povidone-iodine solutions sold as skin disinfectants are NOT suitable for gargling as they contain potentially harmful ingredients that should not be ingested.
“It’s critical that people not gargle with skin disinfectant solutions, including those that contain povidone-iodine,” he says. So, when using povidone-iodine for gargling, be sure to look for solutions such as Betadine formulated specifically as a sore throat gargle, not products intended for cuts and wound care.
[my comment: link to product on Amazon:
https://www.amazon.com/Betadine-Antiseptic-Throat-Relieve-Symptoms/dp/B088LBWDH1 ]
Nebulized Hydrogen Peroxide — Another Prevention Strategy
31 min 19 secHydrogen Peroxide Therapy- Information and Instruction with Dr. Mercola
My Hydrogen Peroxide Video from 2006: https://www.youtube.com/watch?v=M0t1K_-YA30 Subscribe for the latest health news: http://bit.ly/2qLgWRW Visit our website: http://bit.ly/2CA9VGn Listen to our podcasts: http://bit.ly/2X87Z18 Su…www.bitchute.com
While gargling and nasal irrigation may certainly be useful, I believe nebulizing hydrogen peroxide or colloidal silver may be even more effective. Dr. Thomas Levy10 has issued guidance on how to use nebulized hydrogen peroxide for the prevention and treatment of viral respiratory infections, including COVID-19.
To inactivate viruses with hydrogen peroxide, all you need is a face mask that covers your mouth and nose and a nebulizer that emits a fine mist with properly diluted food grade hydrogen peroxide.
Typically, food grade peroxide comes in concentrations of 12%, which must be diluted down to 1% or less before use, as described in the chart below and video above. If you are using 3% hydrogen peroxide, then you would multiply the number in the first column by 4, or divide the second column by 4.
The microscopic mist, similar to smoke or vapor, can be comfortably inhaled deep into your nostrils, sinuses and lungs. Hydrogen peroxide (H2O2) consists of a water molecule (H2O) with an extra oxygen atom, and it is the additional oxygen atom that allows it to inactivate viral pathogens.
Coronaviruses are held together by a lipid (fat) envelope. Soap, being amphipathic — meaning it can dissolve most molecules — dissolves this fat membrane, causing the virus to fall apart and become harmless.
Hydrogen peroxide works in a similar way. You can find more details about the mechanism of action in my previous article, “Could Hydrogen Peroxide Treat Coronavirus?”
Some of your immune cells actually produce hydrogen peroxide to destroy pathogens. By killing the infected cell, viral reproduction is stopped. So, hydrogen peroxide therapy is in essence only aiding your immune cells to perform their natural function more effectively.
Hydrogen peroxide is also a key redox signaling agent that creates oxidative eustress. Contrary to oxidative stress or oxidative distress, oxidative eustress denotes an oxidative challenge that has positive or beneficial effects and is essential in redox signaling.
Many studies have looked into the use of hydrogen peroxide against different pathogens. One of the most relevant is a review of 22 studies, published in March 2020 in the Journal of Hospital Infection. They found 0.5% hydrogen peroxide effectively inactivated a range of human coronaviruses, including those responsible for SARS and MERS, within one minute of exposure.
If you’re already presenting with a runny nose or sore throat, Levy recommends using the nebulizer for 10 to 15 minutes four times a day until your symptoms are relieved. You can also use nebulized hydrogen peroxide for prevention and maintenance, which may be advisable during flu season, or while the COVID-19 pandemic is in full swing. According to Levy:
“As it is a completely non-toxic therapy, nebulization can be administered as often as desired. If done on a daily basis at least once, a very positive impact on bowel and gut function will often be realized as killing the chronic pathogen colonization present in most noses and throats stops the 24/7 swallowing of these pathogens and their associated toxins.
If daily prevention is not a practical option, the effectiveness of this treatment is optimized when somebody sneezes in your face or you finally get off of the plane after a trans-Atlantic flight. Don’t wait for initial symptoms. Just nebulize at your first opportunity.”
Sources and References
- 1, 3 Best Life. April 20, 2020
- 2 BMJ 2020;369:m1324
- 4 Nature 2019; 9 article number 1015
- 5 Infectious Diseases and Therapy 2018; 7(2): 249-259
- 6 New York Times March 29, 2020 (Archived)
- 7 BMC Health Services Research December 16, 2008; 8: 258 (PDF)
- 8 International Journal of Clinical Practice August 6, 2015; 69: 11
- 9 Dermatology 2002;204 Suppl 1:32-6
- 10 MedFox Publishing, Dr. Thomas Levy Curriculum Vitae
- 11, 15 An At-Home Treatment That Can Cure Any Virus, Including Coronavirus by Thomas Levy, MD, JD (PDF)
- 12 Harvard University, January 9, 2017
- 13 Nature Reviews Molecular Cell Biology 2020, DOI: 10.1038/s41580-020-0230-3
- 14 J Hosp Infect. 2020 Mar;104(3):246-251
Let us remember the vaccine was never actually approved and available for the troops. “Equivalent” isn’t the same. If it doesn’t have actual approved label, it isn’t.Austin, who instituted the mandate in August 2021 after the Pfizer vaccine was approved by the Food and Drug Administration
Yes, thank you!Thanks for this info. Appreciate it
View: https://twitter.com/ZombyWoof2022/status/1613268711535681552?s=20&t=QID4NqImQCVlqgQrxWLTRAAm I really on my way to becoming a vegetarian??? I think so!
View: https://twitter.com/RWMaloneMD/status/1613260930854563840?s=20&t=28uP4nZj9Ct0MkmVFVV9nw
A few comments were made requesting info on the hydrogen peroxide nasal rinse. This article has that and much more info in it.
When reading it, I flash back to when they made fun of Trump for wondering if there was a way to get common disinfectants into the body to kill the virus. He was ahead of his time...
ETA: I put a link for the Betadine mouth wash in the article where it is discussed. Amazon is running a promotion right now, so if you order it now, and you order 2, you get one half off so the total price is around $16 for the 2.
(fair use applies)
Is Nasal Irrigation More Important Than Hand-Washing?
Analysis by Dr. Joseph Mercola
January 10, 2023
- Flushing your sinuses may be an effective way to inhibit the progression of a virus such as SARS-CoV-2 by lowering the viral load in your sinuses
- Research has demonstrated that nasal irrigation reduces the symptoms and duration of viral illnesses such as the seasonal flu and common cold
- Nasal irrigation and gargling with hypertonic saline has been shown to reduce the duration of the common cold by 1.9 days and reduce transmission within the household by 35% by reducing viral shedding when done within 48 hours of symptom onset
- You may also be able to reduce the risk of SARS-CoV-2 migrating into your lungs by gargling a saline solution or using a povidone-iodine solution such as Betadine Sore Throat Gargle
- Nebulizing hydrogen peroxide or colloidal silver may be even more effective. A recent review found 0.5% hydrogen peroxide effectively inactivated a range of human coronaviruses, including those responsible for SARS and MERS, within one minute of exposure
By now, you probably understand the importance of hand-washing to prevent the spread of infectious illness. But did you know flushing your sinuses might be an even better way to inhibit the progression of a viral illness such as COVID-19? In an April 20, 2020, article, Best Life features the recommendations of Dr. Amy Baxter, a pediatric emergency medicine physician in Atlanta, Georgia.
Nasal irrigation, she says, is a rarely discussed strategy that can help reduce the progression of illness in those who have tested positive for COVID-19 infection. In an April 2, 2020, response to a BMJ paper about the lack of personal protection equipment on COVID-19 frontlines, professor Robert Matthews also brought up the importance and potential usefulness of oropharyngeal washing to protect health care workers from infection. As reported by Best Life:
“Nasal irrigation, or a nasal wash, has long been considered an effective way to remove viruses or bacteria from sinus cavities.
According to Baxter, recent clinical trials show that nasal irrigation reduces the duration and symptoms for other viral illnesses like flu and the common cold, though it hasn't yet been studied for COVID-19. Still, she has multiple reasons for believing that this approach can be effective in preventing coronavirus from worsening in a sick patient.”
Why Nasal Irrigation?
As noted by Baxter, researchers have found that the viral load of SARS-CoV-2 tends to be heaviest in the sinuses and nasal cavity. Regularly rinsing your sinuses therefore makes sense since it would help clear out the pathogen and prevent it from gaining a strong foothold and migrating into your lungs.
The age and gender discrepancies observed in COVID-19 also supports nasal irrigation. Children are at virtually no risk from COVID-19, while death rates among the elderly are at their highest. More men than women also die from the infection.
“Children don't develop full sinuses until teens; males have larger cavities than women, and the cavities are largest [in those] over 70 years,” Baxter notes.
Research has previously demonstrated that nasal irrigation reduces the symptoms and duration of other viral illnesses such as the seasonal flu and common cold.
In one randomized controlled trial,4 nasal irrigation and gargling with hypertonic saline were found to reduce the duration of the common cold by 1.9 days and reduce transmission within the household by 35% by reducing viral shedding when done within 48 hours of symptom onset.
While it has not yet been studied as a preventive method for COVID-19 specifically, there’s reason to suspect nasal irrigation might be helpful.
Baxter points out that COVID-19 death rates in Southeast Asian countries such as Thailand, Vietnam and Laos have been surprisingly low, and nasal irrigation is common practice in those areas. According to Baxter, some 80% of the Southeast Asian population do it.
How to Irrigate Your Sinuses
Baxter suggests irrigating your sinuses any time you’ve been exposed to an infected individual or test positive for COVID-19. She recommends flushing your sinuses in the morning using a mixture of boiled lukewarm water (8 ounces) and povidone-iodine (half a teaspoon).
Povidone-iodine has been shown to effectively kill not only Klebsiella pneumoniae and Streptococcus pneumoniae bacteria, but to also rapidly inactivate SARS-CoV, MERS-CoV, H1N1 influenza virus A and rotavirus after 15 seconds of exposure.5
The mixture used in this study: 7% povidone-iodine diluted 1-to-30, which equates to a total concentration of 0.23% povidone-iodine, inactivated over 99% of the coronaviruses causing SARS and MERS.
Either a neti pot or NeilMed sinus rinse bottle can be used. The water pressure you get from a sinus rinse bottle can provide a more effective flush. If higher pressure is uncomfortable, a neti pot, which relies on gravity, may be a more comfortable choice. In the evening, Baxter recommends flushing your sinuses again with a mixture of:
8 ounces of boiled lukewarm water
0.5 teaspoon baking soda
1 teaspoon table salt
Gargling May Also Be Helpful
You may also be able to reduce the risk of SARS-CoV-2 migrating into your lungs by gargling. As noted by Dr. Neal Naito in a March 29, 2020, New York Times article,6 while there’s “no firm proof” that gargling can prevent COVID-19, there are virtually no downsides to the advice.
Like Baxter, Naito points out that many East Asian countries such as Japan see gargling as a commonsense hygiene practice.
“In East Asia, particularly in Japan, gargling is strongly encouraged by the national government, along with other practices like hand-washing, wearing face masks and social distancing, as a matter of routine hygiene during the regular cold and flu season.
(Not everyone, though, can gargle effectively, including some people with neck pain, stroke or dementia, as well as children generally under the age of 8.) Most of the early studies suggesting that gargling may help to prevent and treat upper and lower respiratory infections, not surprisingly, come from Japan,” Naito writes.
An over-the-counter povidone-iodine oral gargle solution, used for decades by the Japanese for the treatment of sore throat, appears most useful. One small study from Japan, published in 2002, found patients diagnosed with chronic respiratory disease who gargled with a povidone-iodine solution at least four times a day reduced their incidence of acute respiratory infection by about 50%.
Do Not Use Iodine-Based Skin Disinfectant for Gargling
Importantly, Naito stresses that povidone-iodine solutions sold as skin disinfectants are NOT suitable for gargling as they contain potentially harmful ingredients that should not be ingested.
“It’s critical that people not gargle with skin disinfectant solutions, including those that contain povidone-iodine,” he says. So, when using povidone-iodine for gargling, be sure to look for solutions such as Betadine formulated specifically as a sore throat gargle, not products intended for cuts and wound care.
[my comment: link to product on Amazon:
https://www.amazon.com/Betadine-Antiseptic-Throat-Relieve-Symptoms/dp/B088LBWDH1 ]
Nebulized Hydrogen Peroxide — Another Prevention Strategy
31 min 19 secHydrogen Peroxide Therapy- Information and Instruction with Dr. Mercola
My Hydrogen Peroxide Video from 2006: https://www.youtube.com/watch?v=M0t1K_-YA30 Subscribe for the latest health news: http://bit.ly/2qLgWRW Visit our website: http://bit.ly/2CA9VGn Listen to our podcasts: http://bit.ly/2X87Z18 Su…www.bitchute.com
While gargling and nasal irrigation may certainly be useful, I believe nebulizing hydrogen peroxide or colloidal silver may be even more effective. Dr. Thomas Levy10 has issued guidance on how to use nebulized hydrogen peroxide for the prevention and treatment of viral respiratory infections, including COVID-19.
To inactivate viruses with hydrogen peroxide, all you need is a face mask that covers your mouth and nose and a nebulizer that emits a fine mist with properly diluted food grade hydrogen peroxide.
Typically, food grade peroxide comes in concentrations of 12%, which must be diluted down to 1% or less before use, as described in the chart below and video above. If you are using 3% hydrogen peroxide, then you would multiply the number in the first column by 4, or divide the second column by 4.
The microscopic mist, similar to smoke or vapor, can be comfortably inhaled deep into your nostrils, sinuses and lungs. Hydrogen peroxide (H2O2) consists of a water molecule (H2O) with an extra oxygen atom, and it is the additional oxygen atom that allows it to inactivate viral pathogens.
Coronaviruses are held together by a lipid (fat) envelope. Soap, being amphipathic — meaning it can dissolve most molecules — dissolves this fat membrane, causing the virus to fall apart and become harmless.
Hydrogen peroxide works in a similar way. You can find more details about the mechanism of action in my previous article, “Could Hydrogen Peroxide Treat Coronavirus?”
Some of your immune cells actually produce hydrogen peroxide to destroy pathogens. By killing the infected cell, viral reproduction is stopped. So, hydrogen peroxide therapy is in essence only aiding your immune cells to perform their natural function more effectively.
Hydrogen peroxide is also a key redox signaling agent that creates oxidative eustress. Contrary to oxidative stress or oxidative distress, oxidative eustress denotes an oxidative challenge that has positive or beneficial effects and is essential in redox signaling.
Many studies have looked into the use of hydrogen peroxide against different pathogens. One of the most relevant is a review of 22 studies, published in March 2020 in the Journal of Hospital Infection. They found 0.5% hydrogen peroxide effectively inactivated a range of human coronaviruses, including those responsible for SARS and MERS, within one minute of exposure.
If you’re already presenting with a runny nose or sore throat, Levy recommends using the nebulizer for 10 to 15 minutes four times a day until your symptoms are relieved. You can also use nebulized hydrogen peroxide for prevention and maintenance, which may be advisable during flu season, or while the COVID-19 pandemic is in full swing. According to Levy:
“As it is a completely non-toxic therapy, nebulization can be administered as often as desired. If done on a daily basis at least once, a very positive impact on bowel and gut function will often be realized as killing the chronic pathogen colonization present in most noses and throats stops the 24/7 swallowing of these pathogens and their associated toxins.
If daily prevention is not a practical option, the effectiveness of this treatment is optimized when somebody sneezes in your face or you finally get off of the plane after a trans-Atlantic flight. Don’t wait for initial symptoms. Just nebulize at your first opportunity.”
Sources and References
- 1, 3 Best Life. April 20, 2020
- 2 BMJ 2020;369:m1324
- 4 Nature 2019; 9 article number 1015
- 5 Infectious Diseases and Therapy 2018; 7(2): 249-259
- 6 New York Times March 29, 2020 (Archived)
- 7 BMC Health Services Research December 16, 2008; 8: 258 (PDF)
- 8 International Journal of Clinical Practice August 6, 2015; 69: 11
- 9 Dermatology 2002;204 Suppl 1:32-6
- 10 MedFox Publishing, Dr. Thomas Levy Curriculum Vitae
- 11, 15 An At-Home Treatment That Can Cure Any Virus, Including Coronavirus by Thomas Levy, MD, JD (PDF)
- 12 Harvard University, January 9, 2017
- 13 Nature Reviews Molecular Cell Biology 2020, DOI: 10.1038/s41580-020-0230-3
- 14 J Hosp Infect. 2020 Mar;104(3):246-251
not science, but these kind of well done, edgy pieces probably have a part to play in raising awareness, too.
David Wolfe
@DavidWolfe
Coincidence Theorists
View: https://twitter.com/DavidWolfe/status/1612994071362146309?s=20
So Geert continues to share the science that leads him to teach and believe that a serious outbreak of COVID is inevitable. He admits he was wrong about the timeline but the inevitable has only been delayed. Geert is a scientist, not a Doctor, so Doctors need to listen to the scientists. My takeaway is that he sees XBB1.5 as a strain of Omnicron. There is still one yet to come that will be catastrophic.Here is Geert on January 6th
He speaks in English ... wait for it, 2 minutes in.
Mutation pressure due to Vaccination | Voice for Science and Solidarity
www.voiceforscienceandsolidarity.org
View: https://twitter.com/robertb63886025/status/1613461969381490693?s=46&t=E1G7y9e_Kvcht6f1EZ1Cfg
So he doesn't think XBB1.5 is the 'geert variant' ? I haven't watched it yet, I hope to watch it later today or tomorrow.So Geert continues to share the science that leads him to teach and believe that a serious outbreak of COVID is inevitable. He admits he was wrong about the timeline but the inevitable has only been delayed. Geert is a scientist, not a Doctor, so Doctors need to listen to the scientists. My takeaway is that he sees XBB1.5 as a strain of Omnicron. There is still one yet to come that will be catastrophic.
Yes the date is Nov. 22. Not sure when xbb1.5 became a thing. Thx HDSo he doesn't think XBB1.5 is the 'geert variant' ? I haven't watched it yet, I hope to watch it later today or tomorrow.
Thank you for the link! Good to hear from him. I still wish he'd do a video about what's going on in China...(and I'm guessing since this one was done in Nov, the Chinese outbreak wasn't yet a 'thing' for him to discuss, but again, haven't watched yet)
HD
I guess it wasn’t until late December that it became a thing because CDC dragged its feet getting the word out.Yes the date is Nov. 22. Not sure when xbb1.5 became a thing. Thx HD
Finally!!!crossin fingers n toes, lightin' candles for those whose lost lives linked together to get us to this point. . .
Dr Aseem Malhotra
@DrAseemMalhotra
BREAKING BBC News:
Cardiologist says likely contributory factor to excess cardiovascular deaths is covid mRNA vaccine and roll out should be suspended pending an inquiry.
We did it. We broke mainstream broadcast media
View: https://twitter.com/DrAseemMalhotra/status/1613837487796850688?s=20
View: https://twitter.com/DowdEdward/status/1614008020585054208?s=20&t=sfVXwOW-X0VK5Zcs9qq25gcrossin fingers n toes, lightin' candles for those whose lost lives linked together to get us to this point. . .
Dr Aseem Malhotra
@DrAseemMalhotra
BREAKING BBC News:
Cardiologist says likely contributory factor to excess cardiovascular deaths is covid mRNA vaccine and roll out should be suspended pending an inquiry.
We did it. We broke mainstream broadcast media
View: https://twitter.com/DrAseemMalhotra/status/1613837487796850688?s=20
I don't trust Johns Hopkins. They have been in cahoots with Fauci thru n thru.....More about nosesprays for covid although this is more mainstream.. (vs the iodine and the xlear recommendations).
(fair use applies)Simple spray could keep COVID away
What if preventing respiratory illnesses such as COVID-19 and influenza could be as easy as a quick spritz of nasal spray every morning?medicalxpress.com
Simple spray could keep COVID away
by Gina Wadas, Johns Hopkins University
January 12, 2023
What if preventing respiratory illnesses such as COVID-19 and influenza could be as easy as a quick spritz of nasal spray every morning?
Numerous bacteria and viruses, including those that cause COVID-19 and influenza, enter the body through the lungs when people breathe, resulting in illness. Johns Hopkins engineers have created thin, thread-like strands of molecules called supramolecular filaments that are designed to be sprayed into the nose, blocking those harmful viruses from entering the lungs.
"The idea is that the filaments will work like a sponge to absorb the COVID-19 virus and other viruses before they have the chance to bind to cells in our airways. Even if the therapeutic can block the virus for an hour or two, that can be helpful when people must be in a public setting," said research team leader Honggang Cui, core researcher at the Institute for NanoBioTechnology and associate professor of chemical and biomolecular engineering at Johns Hopkins Whiting School of Engineering.
The team's results appeared recently in Matter, and the work was done through a collaboration with Hongpeng Jia, assistant professor of surgery, and other researchers at Johns Hopkins School of Medicine.
The key to this approach is the way that the filaments carry a receptor called angiotensin converting enzyme-2, or ACE2. These receptors are also found in cells in the nasal lining, the lung surface, and small intestine, and have many biological roles, such as regulating blood pressure and inflammation. The novel coronavirus enters our bodies primarily through interactions with this receptor. The virus's characteristic spike protein clicks into this receptor, much like a key going into a lock, allowing it to enter the cell and replicate. Once the virus is locked into the cell, it prevents the cell from executing its normal functions, leading to and exacerbating infections.
Researchers have long known that adding extra ACE2 into airways can block virus entry, essentially preventing the virus from binding with ACE2 in the lungs. However, since ACE2 has biological functions, simply delivering more ACE2 to the body may have unforeseeable complications. The research team's newly engineered filament, called fACE2, serves as a decoy binding site for the virus, with each filament offering several receptors for the COVID-19 spike protein to attach to, and silences ACE2's biological functions to avoid potential side effects.
"Our plan is that this would be administered as a nasal or oral spray, allowing it to be suspended in the lungs or settle on the surface of airways and lungs. When a person breathes in the COVID-19 virus, the virus will be fooled into binding to the decoy receptor and not the ACE2 receptors on cells," Cui said.
And because the filaments attract SARS-CoV-2's characteristic spike protein, it should work equally well on any current or future variants, the researchers predict.
The team tested its design in mouse models and found their filament was not only present in the rodents' lungs up to 24 hours later, but also elicited no inflammation or obvious damage to the lungs' structures, suggesting that fACE2 may be retained in the lungs for a period of time, and is safe.
While the team's original approach was to design a preventative therapeutic, they say that it also may have the potential to treat people with active COVID-19 infections by thwarting replication of newly acquired viruses.
"We think that fACE2 could also be used on other respiratory viruses that use the ACE2 receptor to infiltrate cells. The filament design is versatile and can be modified to carry various therapeutic proteins that target different receptors," Jia said.
More information: Caleb F. Anderson et al, Supramolecular filaments for concurrent ACE2 docking and enzymatic activity silencing enable coronavirus capture and infection prevention, Matter (2022). DOI: 10.1016/j.matt.2022.11.027
Journal information: Matter
Provided by Johns Hopkins University