CORONA Main Coronavirus thread

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Beijing mandates COVID vaccines to enter some public spaces
By HUIZHONG WU
42 minutes ago

TAIPEI, Taiwan (AP) — The Chinese capital has issued a mandate requiring people to show proof of COVID-19 vaccination before they can enter some public spaces including gyms, museums and libraries, with exceptions only available to those who cannot be vaccinated for health reasons.

The health app that shows a person’s latest PCR test results has been updated to make it easier to access their vaccination status, according to Li Ang, a spokesperson at Beijing’s municipal health commission.

The list of public places requiring vaccination does not include restaurants and offices. The mandate will go into effect on Monday.

“In the normalization of COVID-19 pandemic controls, getting vaccinated is still the most effective measure at controlling the spread of COVID-19,” Li said in an announcement on Wednesday.

More than 23 million people in Beijing have been vaccinated, Li said, which if accurate would cover the city’s entire population and more. A 2020 census found that Beijing was home to some 22 million long-term residents. It is unclear what makes up the discrepancy in the numbers. The Beijing government did not immediately respond to a faxed request for comment on the new measures.

Li said that more than 3.6 million people over 60 years old have been vaccinated. He did not say if they received two shots or three.

A vaccine mandate is not unusual and some major cities in the U.S. required proof of vaccination for entry into restaurants and bars at some point during the pandemic.

However, those mandates did not include spaces like libraries. Few places in the U.S. now actively require proof of vaccination to enter. Most U.S. cities have also rolled back social distancing measures that were implemented in the first year of the pandemic. Certain spaces, like hospitals, still mandate proof of vaccination.

In Beijing and other cities across China, many government facilities already require people to show proof of vaccination before entry.

Online, the announcement drew some anger and pointed questions. Social media users questioned how to obtain a certificate showing one was unsuitable for vaccination, whether the unvaccinated could ride the subway and other logistics of the new requirement.

Chen Yumei, a 48-year-old Beijing resident, said she hasn’t been vaccinated yet because she suffered from hives that doctors had said made her unsuitable.

“A lot of doctors told me I couldn’t, but who’s going to give me the certification for an exception? No one dares to give you this certification,” she said.

“Something like this is too unreasonable,” Chen said. “We’ve already been cooperating with the PCR tests, no matter how hot it is or how long the line is.”

Another Beijing resident, Leo Zhang, said he was confused whether the new policy meant he needed to get a booster or if two doses were enough. He is planning to get a booster shot as a result.

“At least for me, it doesn’t have a big impact, it’s just getting a booster,” said Zhang, who regularly visits the gym.

Others on social media shared an article from last year from Xinhua, an official state media outlet, that quoted National Health Commission officials forbidding local governments from putting forward policies that prevent people from entering places like supermarkets without proof of vaccination.

It is unclear how Beijing’s new directive will be implemented given the national policy. Additional requirements are already in effect for medical workers, delivery workers and public transportation employees, who are all required to be fully vaccinated.
 

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Hong Kong lifts flight ban citing ‘little effect’ on COVID
By ZEN SOO
an hour ago

HONG KONG (AP) — Hong Kong announced Thursday it is shelving a COVID-19 measure that has resulted in dozens of canceled flights in recent months and thwarted travel plans for thousands.

Starting Thursday, the city will no longer ban arriving airline flights just because they’d brought in passengers infected with COVID-19, the government announced.

“The new measure is a decision made by the government after careful review of relevant data and taking into account the current peak period for international students returning to Hong Kong,” a government spokesperson said.

Previously, a five-day flight route ban was imposed on airlines if at least five passengers or 5% of travelers — whichever is higher — tested positive for the coronavirus on arrival. That caused about 100 flight cancellations since the beginning of the year.

The announcement noted that most imported COVID-19 infections could be detected by the coronavirus tests at the airport and in hotels.

The flight suspension rule had “little effect” on preventing imported infections and the risk of those cases causing infection in the community are “relatively minimal,” the government said.

Travelers had griped that the regulation’s last-minute flight cancellations also affected quarantine hotel bookings. Those impacted often had to postpone their rescheduled trips for weeks because hotels tend to be booked out months ahead.

Despite lifting the flight bans, travelers arriving in Hong Kong will still need to test negative for the coronavirus before arriving in the city, serve a mandatory quarantine period of seven days in a designated hotel in Hong Kong, and undergo a series of rapid tests and nucleic acid tests for the coronavirus over a two-week period.

Hong Kong leader John Lee and health authorities have said they are exploring options to keep Hong Kong open to international travelers, including a possible reduction of mandatory quarantine periods.
 

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Norwegian Cruise Line to drop requirement for COVID-19 test
Wed, July 6, 2022, 12:45 PM

MIAMI (AP) — Norwegian Cruise Line is dropping a requirement that passengers test negative for COVID-19 before sailing unless it is required by local rules.

The company said Wednesday that it will drop the testing requirement Aug. 1 except on ships sailing from places with local testing rules, including in the United States, Canada, Bermuda and Greece.

The Centers for Disease Control and Prevention requires pre-trip testing for passengers on 94 ships taking part in CDC's voluntary COVID-19 program, including Norwegian ships that sail in the U.S.

Norwegian requires vaccinated passengers in the U.S. to show a negative antigen test for COVID-19 within two days of their trip or a negative PCR test within three days of sailing. Unvaccinated children under 12 are subject to more testing when they board and leave the ship.

Norwegian Cruise Line Holdings Ltd. said it will relax its testing policy in other countries to be in line with other sectors of the travel industry “as society continues to adapt and return to a state of normalcy.”

The cruise industry complains that when the pandemic hit, it was singled out for a shutdown by the U.S. Centers for Disease Control and Prevention while airlines were not.

Norwegian, which has its headquarters in Miami, operates the Norwegian, Oceania and Regent Seven Seas lines.
 

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North Carolina Physicians Criticize Study Backing Vaccinations for Children
By Matt McGregor
July 6, 2022

A group of North Carolina physicians is criticizing the study used to back the U.S. Food and Drug Administration’s (FDA) decision to grant emergency use authorization for COVID-19 vaccines for 6-month to 4-year-old children.

“It was a weak and underpowered study that in no way proved the efficacy nor safety given the fact that two-thirds of the children that started the study did not complete the study for reasons that are unclear,” Dr. Kristin Strange, a pediatric member with the North Carolina Physicians for Freedom (NCPF), told The Epoch Times.

There was a negative efficacy between the first and second dose, where there was a 30 percent increase in COVID-19 cases in the vaccine group compared to the placebo, Strange said.

“There was no improvement in clinical outcomes after the second dose, which then prompted an add-on third booster dose for these children,” Strange said. “Since 97 percent of children who contracted COVID-19 during the trial did so before the third dose was given—most of whom had mild symptoms—there were only a few COVID-19 cases to base their conclusions, which showed, in the end, a 70 percent efficacy in the vaccine group compared to the placebo; that efficacy decided on by only 10 total children.”

The only child hospitalized in the study, with COVID-19 infection, fever, and seizures; was from the vaccine group, Strange said.

Dr. Dianna Lightfoot, Dr. Weston Saunders, and Dr. Bose Ravenell—also with NCPF—complied a Q&A (pdf) after fielding concerns from parents about the child vaccinations from their research.

‘Eroded Trust’

Flawed and inconsistent testing methods used to justify the rapid push to vaccinate children for COVID-19 have bred wariness in parents, Strange said, creating even more problems.

“We are seeing a progressive rise in overall vaccine hesitance among families who are second-guessing the other established vaccines for their children due to the mistrust in our public health entities, including the FDA and the CDC, given how this COVID-19 vaccine rollout has gone thus far with the heavy-handedness of vaccine mandates and many people witnessing first hand very concerning side effects in themselves, family members, athletes, and their own children,” Strange said.

The eroded trust between the patient, physician, and family could take years, “if not decades,” to heal, Strange said.

The FDA and the CDC didn’t immediately respond to The Epoch Times’ request for comment.

‘Tremendous Risk’

Given that the vaccine was not properly vetted or verified for safety, and can’t actually prevent disease or transmission of the virus to others, injecting healthy children with a novel genetic vaccine that was rushed into development presents a “tremendous risk” that society can’t afford because it leaves children vulnerable to both short term and still yet unknown long-term side effects, Strange said.

“As pediatricians and medical practitioners, we will have no credibility with families and patients going forward with recommendations for current and future childhood vaccines and medical interventions if this vaccine roll-out—especially in children—continues on its current path,” Strange said. “This whole process may in fact result in a need for us to look more intently at our current vaccine schedule and to review the ongoing need for some of them, along with their timing according to the child’s risk of disease and verifying their safety.”

There should also be a review of how those studies were conducted as well, Strange said.

“This includes making sure any adjuvants added, such as aluminum, are within acceptable ranges to be deemed safe for injecting into a mother carrying a developing baby as well as a young infant with rapid brain and body development in those critical first years of life,” Strange said.

‘Medical Freedom’

To raise any of these concerns, however, brings judgment from medical boards, Strange said, which has removed the medical sovereignty of both patient and physician.

“Not only do patients and parents want medical freedom to make their own health care decisions for themselves and their children, but we must also preserve the medical freedom that physicians and medical practitioners have had with regards to making patient-specific recommendations without fear of reprisal or threat of our medical licensure by our medical and specialty boards,” Strange said.
 

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Judge Sides With Parent, Strikes Down Los Angeles School Vaccine Mandate
By Bill Pan
July 6, 2022

A plan to mandate COVID-19 vaccine shots for hundreds of thousands of students in the Los Angeles Unified School District (LAUSD) will remain on pause after a Los Angeles County judge ruled on July 5 that the district lacks the authority to do so.

In his ruling, Judge Mitchell Beckloff of the Superior Court of Los Angeles County sided with a parent, whose 12-year-old son attends a public magnet school in North Hollywood. The parent filed the complaint in October 2021, about a month after the LAUSD announced its vaccination mandate.

Under the district’s mandate, all eligible students aged 12 and above must show proof of COVID-19 vaccination, or get approved for exemptions by Jan. 10 in order to attend school in person. Those who don’t comply would be transferred into the district’s remote learning program, City of Angels, which offers a mixture of live instruction and self-study.

The suing parent, identified as G.F., argued that it is unfair and unlawful for the child, identified as D.F., to have to lose his hard-earned place at a competitive school just because he and his parent have chosen to not get vaccinated on the basis of personal beliefs.

According to G.F., his son had acquired natural immunity after recovering from COVID-19. He also said he worried that vaccinating the child would put the child’s health in jeopardy.

“Either I get him a vaccine that I fear could harm him, or I send him to a virtual school that I know from experience and LAUSD’s own data would prove academically vastly inferior,” the father said earlier this year in a sworn declaration, reported City News Service. “The idea of dumping him into an online school, free of a rigorous academic program and torn away from his like-minded classmates, breaks my heart.”

Beckloff, who wrote in March in a tentative opinion that he might dismiss the case, agreed with the father in his final ruling, acknowledging that if D.F. refuses to comply with the mandate, he will be forced to accept a very different education.

“The [mandate] is not merely about how education is delivered or who may be physically present on campus as the court previously viewed it. Instead, the [mandate] dictates which school the student may attend, and the curriculum he may continue to receive,” the judge wrote, reported the Los Angeles Times.

The judge also noted that the LAUSD mandate is in conflict with California’s public health law, which allows personal beliefs-based vaccination exemptions.

“Judge Beckloff’s ruling confirms that individual school districts do not have the authority to impose local vaccination requirements in excess of statewide requirements,” Arie Spangler, an attorney for G.F., said in a statement. “We are very pleased with the ruling, as it ensures that no child will be forced out of the classroom due to their COVID-19 vaccination status.”

The decision doesn’t have an immediate impact on LAUSD, since the mandate has already been placed on hold after California Gov. Gavin Newsom announced in April that the state would wait for the federal government to give full approval to the COVID-19 vaccine for young children. The Newsom administration and school district have both said they won’t pursue the pediatric vaccine mandate until at least the summer of 2023.
 

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Nearly 22,000 DHS Employees Seek COVID-19 Vaccine Mandate Exemptions
Watchdog urges government to resolve requests
By Zachary Stieber
July 6, 2022

Nearly 22,000 Department of Homeland Security (DHS) employees have sought exemptions to the U.S. government’s federal COVID-19 vaccine mandate, but the requests all remain in limbo, according to newly obtained documents.

Key agencies within DHS could face a massive loss of workers if the requests aren’t resolved, a watchdog warns.

More than 8,100 Customs and Border Protection employees, who include Border Patrol agents, have asked for a medical or religious exemption to the mandate that was imposed by President Joe Biden in 2021. In addition, more than 5,800 Transportation Security Administration workers have requested accommodations, while more than 2,800 Immigration and Customs Enforcement employees have sought exemptions on religious or medical grounds.

None of the requests have been acted upon yet, DHS told the Functional Government Initiative (FGI), the watchdog that obtained the data.

Mandate Halted

Biden ordered agencies to implement the mandate in September 2021. While the government workers were told to get vaccinated, they were also advised that they could apply for medical or religious exemptions.

The Biden administration was sued over the mandate, with lawsuits alleging it was unconstitutional. Feds for Medical Freedom, a group of government workers, filed one of the suits.

The group won an injunction against the mandate in January. U.S. District Judge Jeffrey Brown, a Trump appointee, said the mandate fell outside of the president’s powers.

The government’s vaccine workforce, based on the ruling, told agencies to “take no action to implement or enforce” the mandate.

In compliance with the injunction, “DHS halted the review process and has not taken any action to implement or enforce the vaccination requirement” as of Jan. 24, Rosemary Law, a DHS Freedom of Information Act officer, told FGI in documents reviewed by The Epoch Times.

That means no exemptions have been granted, she indicated.

Limbo

The watchdog asserts the government should continue processing the requests, so that employees know if they’re in danger of being fired.

“They absolutely should have been processing these so that the people who have filled out these exemption requests kind of have an idea of where it’s going to go because, right now, we have 22,000 people wondering if they’re going to have a job,” Pete McGinnis, a spokesman for FGI, told The Epoch Times.

Many of the employees who have asked for an exemption work on immigration matters, including thousands stationed at or near the U.S.–Mexico border. The Biden administration already is grappling with an illegal immigration crisis that has broken records for the number of arrests at the border, and firing immigration officers would make things worse, McGinnis added.

DHS officials didn’t respond to a request for comment.

Of the other DHS components, the number of workers who have asked for exemptions are: more than 1,700 at the Federal Emergency Management Agency, nearly 1,300 at the U.S. Citizenship and Immigration Services, 680 with the U.S. Coast Guard, nearly 500 at the U.S. Secret Service, 333 at DHS headquarters, 167 at Federal Law Enforcement Training Centers, and just over 100 with the Cybersecurity and Infrastructure Security Agency.

The case regarding the mandate has since moved forward. An appeals court panel overturned Brown’s decision, but later dissolved that ruling as the full court prepares to hear arguments from the parties.
 

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Doctor Issues Warning About Giving COVID-19 Vaccines to Babies
'The first thing you look at is risk-to-benefit ratio, and the risk of the vaccine far outweighs the benefit.'
By Patricia Tolson
July 6, 2022

On June 18, Rochelle Walensky, director of the U.S. Centers for Disease Control and Prevention (CDC), “endorsed the Advisory Committee on Immunization Practices’ (ACIP) recommendation that all children 6 months through 5 years of age should receive a COVID-19 vaccine.”

However, another doctor is issuing a warning about the risks of vaccinating babies.

According to Dr. Syed Haider—an internal medicine specialist and founder of mygotodoc.com—”the risk of the vaccine far outweighs the benefit.”

As The Epoch Times reported May 26, Haider has focused on the prevention and treatment of the CCP (Chinese Communist Party) virus through his online initiative by providing easy online access to off-label prescriptions such as ivermectin, hydroxychloroquine, budesonide, and protocols for COVID, long-COVID, and vaccine injuries.

Haider began this journey in December 2020, after realizing that the United States had offshored almost all prescription drug manufacturing to unfriendly nations like China.

According to Haider, dissenting voices in the debate over how to manage and treat the CCP virus have been muzzled and censored from the very onset of the pandemic and they are now being threatened with the loss of their medical licenses. Because of this, Haider has had to retain an attorney.

Despite the threats, Haider said he refuses to remain silent when the government issues a recommendation that children as young as 6 months old be vaccinated for a disease that poses little, if any, threat to their lives.

Risks and Benefits

“Whenever you are evaluating whether or not to carry out a medical intervention the first thing you look at is risk-to-benefit ratio,” Haider told The Epoch Times, “and the risk of the vaccine far outweighs the benefit.”

As Haider explained, “the supposed benefit of the vaccine is that it’s going to prevent COVID, reduce the severity of COVID, and prevent you from dying of COVID.”

According to Haider, “the risk of COVID in children is zero.” Data released by the CDC seems to confirm his opinion.

According to the latest data from the CDC, 431 children—newborn to age four—have died of COVID. Conversely, the deaths of more than 1 million people over the age of 19 have been attributed to COVID, and 521,293 of those were older than 75.

When asking what really caused the deaths in children diagnosed with the CCP virus, the answer will depend on who is speaking.

The Mayo Clinic says “babies under age 1 might be at higher risk of severe illness with COVID-19 than older children.” Johns Hopkins University says “COVID-19 symptoms in kids and babies are generally milder than those in adults, and some infected children may not have any signs of being sick at all.”

The CDC says that while serious cases have occurred, the majority of newborns who test positive for the CCP virus have only mild symptoms or none at all and they recover from the illness.

“Maybe you can say one in a million or one in ten million children might die of COVID,” Haider said. “But even then it may not have been COVID. It’s usually that they die of something else, they had cancer or some other autoimmune disease, something else serious that killed them. It wasn’t COVID itself.”

A 2020 report by the CDC showed that nearly three-quarters of COVID-associated deaths among infants, children, adolescents, and young adults have occurred in patients aged 10 to 20 years old, with a disproportionate percentage among young adults aged 18 to 20 years and among Hispanics, blacks, American Indians, Alaska Natives, and those with underlying medical conditions.

In another 2020 report by the CDC, 75 percent of those under 21 who died of the CCP virus “had underlying medical conditions, such as asthma, obesity, neurologic/developmental conditions, and cardiac conditions.” Virtually all of the pediatric deaths “met the COVID-19 case definition” and 12 percent “met the multi-inflammatory syndrome in children.”

‘Problems With the Trials’

According to Haider, there are also “a number of problems with the trials.”

As Haider explained, the serious adverse event rate in the trials was one out of 71 children, but the trials were too small to evaluate whether any children would have been prevented from dying. The data from the Pfizer trial (pdf) showed there were 5,000 child participants, and the trial was stopped after two shots based on the assumption that these would be effective.

But once the researchers actually ran the numbers and got the final efficacy numbers, they realized it was not effective.

“They had already unblinded the trial and vaccinated about 58 percent of the placebo group. So you lost the placebo group,” Haider said. “It’s no longer a randomized trial. It’s no longer double-blinded. Then they decided to extend this complete sham of a trial and give it a third dose. Throughout the trial, for all of the efficacy numbers they report at 80 percent efficacy in the Pfizer trial seven days after the third dose, and that’s based on 10 cases of COVID-19, seven in the placebo group and three in the vaccine group. The problem with all of their efficacy numbers, including this 80 percent number, is that none of them are statistically significant.

“Remember, one in 70 children had a serious adverse event in the trial,” Haider reiterated. “This is the best possible data Pfizer can present? I am sure the actual adverse event rate is far higher and the actual efficacy is far lower. They fudge the numbers. A court is going to have to order the release of the actual documents, just like they had to order it for the adult trials. Then we’ll know the truth. We’re now finding the truth about the adult trials and we’re discovering it was never actually 95 percent effective.”

Table 20 showing First COVID occurrence after one dose for children between two to five years old. This table shows the first occurrence of COVID-19 infection after one dose of the vaccine for children 2 to 5 years old, from the Vaccines and Related Biological Products Advisory Committee Meeting report dated June 15, 2022. (Food and Drug Administration)

According to a report by The New York Times, efficacy and effectiveness are related to each other, but they’re not the same thing, and it’s crucial not to mix them up.

“Efficacy is just a measurement made during a clinical trial,” Naor Bar-Zeev, an epidemiologist at the Johns Hopkins Bloomberg School of Public Health, told The New York Times. “Effectiveness is how well the vaccine works out in the real world.”

According to Toby Rogers of Children’s Health Defense, “Pfizer’s manipulation and misrepresentation of its Phase 2/3 clinical trial date for COVID-19 vaccines for kids under 5 is dishonest and unethical and makes the data functionally useless for making decisions.”

In an article posted to the Children’s Health Defense website, Rogers said Pfizer began vaccinating the placebo group in the children’s vaccine trial “to destroy the control and eliminate any long-term safety data.”

Then in early December 2021 when the data showed the trial had failed, Pfizer enrolled more children to administer a third dose in an attempt to save the trial, Rogers said.

“It was always probably around 20 percent at best, if not negative efficacy,” Haider insisted, “and that was based on examining the data Pfizer actually collected and now people are going back and looking at it and seeing Pfizer was not being honest with us. They weren’t being open. They didn’t show us everything that they knew. So I have serious reservations about these vaccines.”

The Epoch Times has reached out to Pfizer for comment.

Antibody-dependent Enhancement

“People need to wake up,” Haider warned. “The phones of congresspeople should be ringing off the hook. We should be demanding that this stop. People need to be marching in the streets. Unfortunately I feel like I’m preaching to the choir because the only media outlets that give me a voice are outlets that people go to who already mostly agree with what I’m saying. But that choir needs to get out into the streets and raise hell until people wake up. We’re standing by and allowing a genocide. We have to stop mincing words. Luc Montagnier, before he died, warned [about] antibody-dependent enhancement.”

Montagnier, the late French virologist who won the Nobel Prize in 2008 for his work identifying HIV as the virus that causes AIDS, said in May 2021 that the COVID-19 vaccines were creating the variants and leading to a condition called antibody-dependent enhancement (ADE).

As Haider explained, the way ADE works is the first time a person is exposed to the infection after getting the COVID vaccine, they may be OK with it. The second time, they might feel a little worse. The third time is when the ADE really kicks in. After the third exposure, they may have a more enhanced infection because of the unnatural vaccine antibodies.
These antibodies actually trigger a worse infection, and that’s the greatest risk here, he said.

Haider said that in all vaccine trials ever performed on animals, all of them ended up with ADE enhancement, and repeated exposure to the infection they were vaccinated against eventually caused all of them to die
“This is the first coronavirus vaccine trial in human beings, and even though we’ve gotten rid of the placebo group in all the trials, it’s still a trial,” Haider asserted. “The trials are over and there are so many problems with the children’s trial. It’s so egregiously wrong. The adult trial was bad to being with, but not near as bad as this one.”

Haider is also aware that social pressure to vaccinate babies is strong.

“I would just tell people to imagine lemmings running off the cliff and you’re one of them,” he said.

What are the chances of a child actually dying from the vaccine? Haider said some estimates are as high as one in 100. Some are as low as one in 1,000.

“Let’s say someone puts a gun to your child’s head and says there’s a one in 1,000 chance that when I pull the trigger, I will kill them,” Haider suggested. “We have to reframe the discussion for people to try to kick them out of this trance they’re in. In a just and sane society, we would be removing children from these parents or putting the parents in jail, and the doctors in jail, and the Pfizer executives and most of the White House and everyone at the CDC in jail.”

“The evidence is there,” Haider insisted. “It’s staring people in the face. You don’t even have to say there’s a conspiracy.
The data speaks for itself.”
 

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Evil In Our Time: Naomi Wolf on the Covid Response
By Thorsteinn Siglaugsson
July 6, 2022

What changed in March 2020? How have things played out? What are the causes? What can we expect, looking ahead?

Those are the key questions Dr. Naomi Wolf addresses in her new book, The Bodies of Others – The New Authoritarians, COVID-19 and The War Against the Human (All Seasons Press, Fort Lauderdale, May 2022).

Naomi Wolf is perhaps best known as a chief spokeswoman for third-wave feminism, a bestselling author and advisor to the campaigns of Bill Clinton and Al Gore. In her new book, Wolf‘s subject is not so much the SARS-CoV-2 virus as the worldwide reactions to its spread, and the consequences of those reactions. Reactions unprecedented in their severity; never before have whole nations been locked up in their homes for weeks, even months on end, to battle a respiratory virus.

Wolf‘s book is a travel through time, starting in March 2020, ending this spring. She switches between discussion and analysis of the situation at each stage and different aspects of it, and a kind of personal diary of how she and those around her were affected.

The book starts with a description of normal pre-pandemic life. The author is at a conference in London surrounded by friends, when she first hears about the lockdown in Italy. This is March 8, 2020. Reflecting, Wolf now sees the news of this first lockdown in Europe as an indication of a strike against the foundation of free Western society: “The flower of Europe was being struck down.”

She moves on to give us a vivid picture of normal life in her New York neighbourhood in the Bronx, its bustling life in all its diversity, suddenly struck down by the lockdown. She and her husband leave the city: “We had both been in conflict areas and we had both lived in close societies – we recognized their movements. We both knew something very bad was on its way; whether natural or political, or both, we could not yet tell.”

To Wolf, lockdown is more than just a way to slow the spread of a virus; it is an abandonment of free society; it signifies a new kind of society; a totalitarian oligarchy, and the fact that we allowed it means we have lost our freedom for the unforeseeable future.

Wolf was not a skeptic from the outset. At first she believed the official narrative, feared for herself and her loved ones, but slowly she started to discover the strange discrepancy between the narrative and the facts. She started questioning the data presented, the usefulness of the countermeasures, the psychological harm of mask-wearing, especially to children, and she describes how perplexed she was witnessing the utter lack of critical thinking on behalf of the media. She discovers how the fear of the virus has turned into a cult, the virus taking on the form of “Milton’s Satan.”

Wolf discusses the interests at play and explains how lockdowns have benefited certain business sectors, especially Big Tech, large corporations at the expense of small businesses. She suggests the proliferation of restrictions may have been driven by the elites, with a goal of disempowering the masses in order to grab their assets. The fact that someone benefits from a situation is of course not proof they caused it. But the financial interests are certainly there and there is little doubt that once the lockdowns and restrictions were in place, many of those who gained the most by them have certainly done much to support the narrative.

To Wolf, this is not about a conspiracy, but a mindset of arrogance and indifference among the elites of society: “But the point was that these people did not need to gather in the shadows or be part of a cabal. Why would this group need a secret sign or a secret meeting? They simply owned the global stratum in which they operated, and they were accountable only to one another.”

In the early days of the Covid-19 pandemic, Italian philosopher Giorgio Agamben analyzed the situation based on three key concepts in his philosophy, Homo Sacer, the State of Exception and Bare Life. Homo sacer is someone who is at the same time sacred and excluded. Homo sacer has in some way broken the taboos of society and is therefore already consecrated to the gods, he can be killed with impunity, but he cannot be sacrificed; he is subject to the power of government, but not protected by the law.

Homo Sacer is condemned to bare life, zoe in the original Greek sense; existing not as a citizen, but as a human stripped of all rights to take an active part in society. The state of exception is realized when law and constitution are abandoned and the executive arm of the state takes the reins, usually based on a declaration of a state of emergency.

As Agamben explains his seminal work, State of Exception, the Third Reich was based on a state of emergency throughout, as the Weimar constitution was in fact “unplugged” right at the beginning, while formally being unchanged the whole time.

Who are the homines sacri? In Biblical times the lepers, in modern times the prisoners of Auschwitz, refugees; homeless, stateless, at the mercy of the charity of foreign rulers.

Agamben’s suggestion, in his first blog posts on the coronavirus in 2020, is that with the lockdowns and other restrictions we have all become homines sacri; we are outside civil society, yet subject to the power of the rulers, unlimited now, based on the emergency declarations.

We are all homines sacri now, Agamben says; a long-term development has culminated in biopolitical totalitarianism. But as Wolf shows us, we may need a bit deeper analysis: She describes the joy of meeting up with her health-freedom friends in the woods late last year, away from the prying eyes of the police and the panicked, vaccine touting self-righteous majority.

And those people, the health-freedom group in the woods, they may be the homines sacri of our time, outside of society, they have broken the taboos, they are a threat to the obeying mass, to the friends who refuse to meet up with an unvaccinated person.

But still, those people, hiding away in the woods, talking, hugging, free from fear; those people are free. Free in the sense they can live and interact as normal human beings. It is here where the glimpse of hope lies according to Wolf; within the biopolitical regime, it is the outlaw, homo sacer, who still enjoys some level of freedom.

Then, let us look at the citizens of Wuhan in early 2020 or in Shanghai just now. Stripped of their citizen’s rights for sure, but more importantly now stripped of even life as an outcast, as homo sacer. Isolation, deprivation of human connection; this is the essence of the lockdowns; they signify the abolition, not only of rights and freedom, but of our existence as humans.

And what of those still in the grip of an absurd narrative, those who obey without questions, who ostracize their neighbours for not wearing a mask, for refusing the vaccine? They are surely still part of society, but are they free? “A fat servant is not a great man. A beaten slave is a great man, for it is in his heart that freedom resides,” to quote Icelandic author Halldor Laxness’s 18th century historical roman Iceland’s Bell.

Broadly speaking we can distinguish between three layers of freedom. The outermost layer is the freedom to work, to make money and keep the proceeds of your work. This is what political debate is mostly about in a free democratic society; how high should taxes be, to what extent should business be regulated and so forth.

The next layer is the freedom of expression and freedom to influence society through political participation. This layer of freedom is generally not debated in free democracies.

But within this layer there is yet another one; the freedom to live as a human being. The freedom to go to a restaurant or go shopping, to go for a walk, the freedom to meet your friends in the park, the freedom to recognize facial expressions, the freedom to smile and be smiled at. And of course the freedom to decide for yourself whether or not to be medicated. It is this layer of freedom that was being attacked during the coronavirus scare, by the authorities, by the media, and, first and foremost, by a hypnotized mass scared out of their wits over a virus.

This layer of freedom is so fundamental that it isn’t even a part of the definition of freedom. It is like the freedom of the horse to sprint, of the dog to bark. It is our freedom to live according to our nature.

The Bodies of Others is a valuable account of an unprecedented situation. Wolf paints a vivid picture of the contrast between normal human life and life under Covid restrictions. She describes the despair of the children deprived of the company of their peers, the emptiness in the eyes of the old and frail kept away from their loved ones by force, withering away in isolation, the crushed communities.

How basic moral principles, empathy and respect for other people’s privacy evaporate as the state assumes a “central role, and limitless authority, in managing our own bodies and the bodies of others.”

Wolf wonders about the possible causes. Unlike many authors, she does not offer a single, simple explanation, no single culprit; no conspiracy at play. “How could otherwise nice people have come to do such evil?” she asks. “How could they have allowed the suppression of young children’s respiration or consigned friends and colleagues to eat in the street like outcasts? How could it have happened in “enlightened” New York City that cops would have been sent to arrest a woman with a terrified nine-year-old child for trying to visit the Museum of Natural History without “papers?” To Wolf, this suggests “evil beyond human imagination,” a “spiritual dimension of evil.”

To her own surprise, and as it seems a bit of embarrassment as an enlightened modern intellectual, Wolf turns to her Jewish religious tradition “in which Hell (or “Gehenom”) is not the Miltonic hell of the later Western imagination, but rather a quieter interim spiritual place.”

And this is where the battle takes place, “between the forces of God and negative forces that debase, that profane, that seek to ensnare our souls. We have seen this drama before, and not that long ago.”The Bodies of Others is a personal, deeply empathic and excellently written tribute to the innermost layer of freedom, the very core that defines us as human beings. Or in Naomi Wolf’s own words: “The object of this spiritual battle? It seemed to be for nothing short of the human soul.”
 

Heliobas Disciple

TB Fanatic
(fair use applies)

University Vaccine Mandates Must End Now
By Cathy Stein
July 6, 2022

Last academic year saw most colleges and universities impose some sort of requirement for students, faculty and staff to take the COVID-19 vaccine. While some universities allowed exemptions for religious and/or medical reasons, some did not.

Now a new academic year is around the corner, and things have changed slightly. Some universities have dropped their mandates, others have become more equitable in allowing religious and/or medical exemptions in light of lawsuits either they have faced or neighboring institutions have faced, and still others are still mandating the vaccine, requiring students, faculty and staff to renew exemptions if they had them.

While the scientific justification and ethical basis behind these mandates was questionable last year, with an additional year of research, mandates are even more controversial. Here I present the latest objections to these mandates.

Mandates are not scientifically justified

Scientific studies, reports by health agencies, and other public data have generally shown that vaccination does not prevent infection, thereby not preventing transmission.

Multiple studies (published by the CDC, researchers at the University of Wisconsin, and researchers at Oxford in the UK) have shown that viral loads and/or infection rates are similar in vaccinated and vaccinated individuals. This is important because it is generally understood in infectious disease epidemiology that transmission probability is highest in individuals with the highest viral loads. Another study showed that the Delta variant can transmit easily from vaccinated people to their household contacts, and that the peak viral load in vaccinated remained similar to the unvaccinated.

Even the WHO warned that “There is now consistent evidence that Omicron is spreading significantly faster than the Delta variant” and “And it is more likely people vaccinated or recovered from COVID-19 could be infected or re-infected”. They further suggested that the omicron variant of COVID-19 is “markedly resistant” to the current COVID-19 vaccines, antibody treatments and COVID-19 vaccine booster shots.

A recent tweet by Dr. Vinay Prasad illustrates the vaccine’s decreased effectiveness over time, especially in response to specific variants of the virus. Here is the figure from that tweet, showing how vaccine effectiveness plummeted once the omicron variant became the predominant variant.

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This is consistent with several reports in the media, multiple scientific studies, and multiple op-eds by doctors showing waning effectiveness of the vaccine and high case numbers in population groups with high vaccine coverage.

Moreover, studies from the Cleveland Clinic, researchers in Israel, and another study out of Israel have also shown that protection against future infection is equivalent between vaccinated individuals and individuals who have acquired immunity naturally. Dr. Martin Kuldorff has written on this as well. However, universities have stated that immunity, demonstrated by positive antibody responses, do not count towards the vaccine mandate. If immunity doesn’t matter, what is the point of the vaccine mandate?

Mandates are unethical

The ethicality of vaccine mandates has been examined elsewhere in articles by a faculty person in philosophy and humanities, discussing the importance of not violating one’s conscience, and my previous article with an interview with Dr. Alvin Moss, the Director of the West Virginia University Center (WVU) for Health Ethics and Law.

In short, because these mandates threaten an individual’s education and/or career stability, they are coercive and impose an undue influence. Both of these factors violate informed consent, a keystone of medicine. My interview with Dr. Moss also tore apart other arguments in favor of mandates, such as “community ethics” and the idea that “public health ethics supersedes all other ethics.” This argument falls apart because the vaccine is not effective, as described above.

Another issue is that forced vaccines violate sincerely held religious beliefs. The Christian perspective on this is described nicely by the Warrenton Declaration, written by a group of pastors.

Last is the issue of risk. While public health professionals, academics, and health care professionals disagree about the degree of risk associated with these vaccines, the fact is that the risk is non-zero. Dr. Paul Alexander’s substack provides a succinct list illustrating these risks. One recent article suggested that the FDA glossed over important severe adverse effects associated with the vaccine.

Even the peer-reviewed scientific literature describes the severe reactions due to the vaccine. A systematic review of the literature summarized adverse reactions to the vaccine, including thrombocytopenia, thrombosis, anaphylaxis, and even death. While in many instances causality could not be proven, it could not be excluded either.

The authors stated that although these severe adverse events are rare, when a global population is exposed to this vaccine, the numbers could still be significant. Another mini-review adds pericarditis, myocarditis, and Guillain-Barré syndrome to this list of adverse reactions.

Most recently, a large national study in France, published in Nature Communications, found that vaccination with both these mRNA vaccines was associated with an increased risk of myocarditis and pericarditis within the first week after vaccination, and that this was most pronounced in younger individuals.

Further, these authors discussed that there is likely a causal link between the vaccine and these events. A recent article in the Brownstone Institute by Dr. Martin Kuldorff also closely examined the adverse effects associated with the vaccine. In summary, severe adverse reactions do occur, and might be more likely in younger (college-aged) individuals. When there is a risk of severe outcome in a population group where the COVID-19 infection fatality rate is low, vaccine mandates are unethical.

Mandates don’t even work

While there are likely many examples of the failure of vaccine mandates on college/university campuses, two are noteworthy. First, a tweet by Dr. Andrew Noymer, faculty at UC Irvine, presented that university’s COVID-19 dashboard, noting that in order to work at or attend UC Irvine, one had to be fully vaccinated and boosted with very rare exceptions.

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Dr. Noymer’s tweet goes on to state that he in fact was both vaccinated and boosted, but also noting “It’s a big deal to fire someone. Doing so for such a leaky vaccine is not without its issues.”

In another example, back in the fall semester, a twitter thread by Dr. Aaron Kheriaty put a spotlight on Cornell University, which shut down its campus due to high COVID-19 case counts . Dr. Kheriaty’s tweet stated that Cornell had a vaccine mandate, “purging” all unvaccinated students. The 3% positivity rate was called “significant” by the university’s president, but none of the cases were severe, and virtually every case occurred in fully vaccinated individuals.

These situations are similar to outbreaks reported on cruise ships. Cruise ships have extremely strict vaccine mandates, requiring all passengers to be fully vaccinated. And yet, a Carnival Cruise Ship that left Miami on April 17 was investigated for an “outbreak” because 0.3% of the people on the ship tested positive for COVID-19. Additional instances like this have been reported in the media. In sum, strict vaccine mandates do not result in zero transmission.

Conclusion

One of the most nonsensical aspects of continuing COVID-19 vaccine mandates is that individuals who survived the mandates last year – that is, were fortunate enough to be granted religious and/or medical exemptions – have to reapply this year.

Did these religious reasons suddenly change without the person complying with the mandate initially? Did these medical reasons that were severe enough to compel a physician to write an exemption suddenly go away?

Maybe either possibility did happen in some cases. But more likely, this is an exercise in obedience, or perhaps to wear down the morale of the individual. Both possibilities are not conducive to a healthy learning or working environment.
 

Heliobas Disciple

TB Fanatic
(fair use applies)

Uruguayan Judge Demands Government, Pfizer Turn Over Documents as Court Considers Request to Halt COVID Vaccines for Kids
Uruguayan government officials and Pfizer d to appear in court Wednesday to provide documents for review regarding vaccine ingredients, adverse effects and contracts shielding the pharma giant from liability.
By Megan Redshaw
07/06/22

Uruguayan government officials and Pfizer on Wednesday appeared in court after a judge gave them 48 hours to present detailed information on Pfizer’s COVID-19 vaccine while the court considers an injunction request to halt COVID-19 vaccinations for children 5 and older.

Judge Alejandro Recarey of the Administrative Litigation Tribunal used his inquisitorial powers to demand the Uruguayan Ministry of Public Health, State Health Services Administration and the President’s Office submit all information regarding the contracts for the purchase of COVID-19 vaccines, including contractual information related to any clauses of civil indemnity or criminal impunity of the suppliers in the event of adverse effects.

According to a court order released on Saturday, Judge Recarey ordered Pfizer and government officials to:
  • Provide full and unredacted, certified copies of “each and every one of the purchase contracts (as well as any other related negotiation agreement), of the so-called anti-COVID vaccines that you have signed, own or are simply within your reach.”
  • Explain whether “these instruments” contain clauses of “civil indemnity and/or criminal impunity of the suppliers regarding the occurrence of possible adverse effects.”
  • Provide extensive detail about the biochemical composition of “so-called vaccines against SARS-CoV-2 in supply to the national population, especially the one aimed at children.”
  • Explain if the “different doses are distributed in batches or differential (different) items,” and if so, “clarify for what reason, and based on what criteria, each would be provided to different population levels, whether the drugs in each batch are diverse by their content and how and for whom they would be distinguishable. If it “turns out to be the real existence of different lots,” doses of each are “requested for judicial expert examination.”
  • Specify if the “so-called vaccines” contain messenger RNA by explaining, if necessary, what that means. Explain what “therapeutic or extra therapeutic consequences — adverse or not — [mRNA] can have for the person inoculated with it. It must be specified with regard to the latter, and in a negative hypothesis in terms of alleged damages, if there is indeed — with scientific rigor — the possible safety of the messenger RNA, or if there is simply a lack of information on the point.”
  • State “very specifically and beyond what has been inquired, it is requested that it be said if it is known to you that those labeled as vaccines contain or may contain nanotechnological elements. Clarifying, if not, whether such a temperament would arise from an effective verification of its absence, or from mere ignorance of the components of the referred ‘vaccinal’ substances.”
  • Certify whether the substances contained in the “so-called vaccines” supplied in Uruguay are experimental or not. That is, “explain in full and detail whether they are approved by the U.S. Food and Drug Administration (FDA), or equivalent body, according to the usual protocols, or if they have some other type of emergency permission.” If this is the case, explain “granted by whom and with what guarantees and based on what regulations.”
In short, you “must also respond if you are aware that either the manufacturer and/or supplier, or any academic or governmental body (domestic or foreign), have admitted — in any way that may be — the experimental nature of the aforementioned vaccines.”
  • Present complete and up-to-date information in your possession about “what is scientifically known — and what is not known — about the effectiveness of those labeled as vaccines” and their possible short, medium and long-term adverse effects.
  • “Provide official figures that demonstrate the negative or positive incidence of so-called vaccination in the number of infections and deaths diagnosed with COVID from the beginning of the campaign to date.”
  • State whether “studies have been carried out to explain the noticeable increase in deaths for COVID-19 since March 2021 or if information is in your possession — with sufficient scientific support and evidence — about it.”
  • Provide information on the total number of deaths in Uruguay due to COVID-19 since the beginning of the “so-called pandemic,” the global average age and how many were for “COVID-19 in an exclusive causal relationship” and how many were “with COVID-19” — that is, with the presence of the virus, but was not the main cause of death.
  • “Demonstrate scientifically — with evidence of national or international studies that have been done — whether the status of non-vaccinated poses a health hazard to the entire population or third parties.“
If it is the case, two other things will be required: the determination and demonstration of the degree of danger, and the reason that explains why, if this were eventually the case,” vaccination would not have been mandated. Prove whether both the vaccinated and unvaccinated infect equally. If they do not, explain what this would be like and in what proportions — and prove what is stated.
  • Clarify the reasons for the “lack of preview informed consent, in relation to the act components of what the government itself presents as a vaccination campaign.”
  • “Detail, with first and last names, the identity of the professional technicians who have directed and direct the aforementioned campaign, or anyone who has provided advice at any level.”
Also provide relevant data for their location “for their judicial interrogation, adding to the required information, data about whether any of them are part of any foreign governmental or para governmental organization, or they have worked for one of them in any way, or, where appropriate, manage in a multinational company” focused on healthcare. “Detail, if necessary, the personal names and organizations or companies involved.”
  • Explain if alternative therapies for COVID-19 have been studied for any variants. If not, clarify why those were not explored. “If positive, give the research results — giving an account of whether those were used in Uruguay or not.”
For the latter option, provide the reasons that would have been taken to discard the use of alternative therapies, adding whether or not “you know that they have been used in other countries successfully, still relative, or not.”

The order also required Pfizer to state within 48 hours whether it has “admitted, in any area, internal or external to it and its partners, the verification of adverse effects” of its COVID-19 vaccines in children.

“I applaud Uruguayan judge Recarey for posing many tough questions to Pfizer over its COVID shots and the contracts it imposed on Uruguay,” Mary Holland, president of Children’s Health Defense (CHD), told The Defender in an email.

“From the beginning, Pfizer has hidden its data and liability-free contracts to avoid liability from the shots,” Holland said.

She explained:

“Many countries, including those in Latin America, have relied on U.S. regulatory agencies in the past to guide health policy. But the U.S. regulatory bodies have failed regarding COVID.

“There is no scientific or ethical justification to authorize COVID shots for children, as some countries, including Denmark, now acknowledge. We know that children are at almost zero risk of dying from COVID. The FDA has extended Emergency Use Authorization for the Pfizer-BioNTech vaccine while illegitimately ‘approving’ Comirnaty, thus engaging in a fraudulent ‘bait-and-switch’ scheme to avoid all liability while hawking ‘approved’ vaccines.”

Holland said CHD is currently pursuing two lawsuits against the FDA for its arbitrary and capricious decisions on COVID-19 shots, and she is “pleased to see that other countries are stepping into the scientific and legal breach.”

“I hope Pfizer complies with the judge’s order, but given its long criminal rap sheet, it remains to be seen,” Holland added.

Dr. Salle Lorier on Twitter called Judge Recarey’s historic ruling a “judicial Maracanazo,” and posted a video explaining the order.

Fallo historico en Uruguay, un verdadero “Maracanazo judicial”;Juez ordena al Gobierno mostrar contrato de las vacunas y múltiples medidas investigativas, como por ejemplo, declaración de autoridades de Pfizer. Video explicativo del fallo del Juez Recarey https://t.co/35tSe599CP
— Dr. Salle Lorier (@sallelorier) July 2, 2022

Although Judge Racarey took it upon himself to review data presented by Pfizer and government officials on COVID-19 vaccines, Uruguay is one of 47 co-sponsoring countries that agreed to the Biden administration’s amendments to the World Health Organization’s (WHO) 2005 International Health Agreements that attempted to place member states’ health sovereignty in the hands of WHO Director-General Tedros Adhanom Ghebreyesus and its regional directors.

U.S. judge requires FDA to turn over Pfizer COVID-19 documents

This is not the first time government officials or Pfizer have been required to turn over data regarding COVID-19 vaccines.

A federal judge on Feb. 2 rejected a bid by the FDA, with the support of Pfizer, to delay the court-ordered release of nearly 400,000 pages of documents pertaining to the approval of Pfizer’s COVID-19 vaccine.

Federal Judge Mark Pittman of the U.S. District Court for the Northern District of Texas issued an order requiring the FDA to release redacted versions of the documents in question according to the following disclosure schedule:
  • 10,000 pages apiece, due on or before March 1 and April 1, 2022.
  • 80,000 pages apiece, to be produced on or before May 2, June 1 and July 1, 2022.
  • 70,000 pages to be produced on or before Aug. 1, 2022.
  • 55,000 pages per month, on or before the first business day of each month thereafter, until the release of the documents has been completed.
The ruling was part of an ongoing court case that began with a Freedom of Information Act (FOIA) request filed in August 2021 by Public Health and Medical Professionals for Transparency (PHMPT).

PHMPT, a group of more than 30 medical and public health professionals and scientists from institutions such as Harvard, Yale, and UCLA, in September 2021 filed a lawsuit against the FDA after the agency denied its original FOIA request.

In that request, PHMPT asked the FDA to release “all data and information for the Pfizer vaccine,” including safety and effectiveness data, adverse reaction reports, and a list of active and inactive ingredients.

The FDA argued it didn’t have enough staff to process the redaction, claiming it could process only 500 pages per month. This would have meant the cache of documents would not be fully released for approximately 75 years.

In his Jan. 6 order, Pittman rejected the FDA’s claim and instead required the agency to release 12,000 pages of documents by Jan. 31 and an additional 55,000 pages per month thereafter.

Pfizer responded to the Jan. 6 order with a request to intervene in the case for the “limited purpose of ensuring that information exempt from disclosure under FOIA is adequately protected as FDA complies with this court’s order.”

Pfizer claimed to support the disclosure of the documents, but asked to intervene in the case to ensure that information legally exempt from disclosure will not be “disclosed inappropriately.”

Lawyers for PHMPT, in a brief submitted Jan. 25, asked Pittman to reject Pfizer’s motion, prompting the Feb. 2 order.

The first batch of documents produced in Nov. 2021, which totaled a mere 500 pages, revealed more than 1,200 vaccine-related deaths within the first 90 days following the release of the Pfizer-BioNTech COVID-19 vaccine.

Since then, thousands of documents released as a result of Pittman’s court order raise serious questions about the data used by U.S. regulatory agencies to justify the authorization and approval of Pfizer and BioNTech’s COVID-19 vaccines.
 

Heliobas Disciple

TB Fanatic
(fair use applies)

England: Excess Deaths on the Rise But NOT Because of COVID – Experts Call for Investigation
By Jim Hoft
Published July 6, 2022 at 9:25pm

The death toll in England and Wales continues to rise, even though Covid-related deaths have dropped.

As a result, health experts have requested an immediate investigation into the source of the rising non-Covid excess death.

Recent data from the Office for National Statistics (ONS) showed 1,540 excess deaths in the week ending on June 24. However, only about 10% of those deaths were caused by Covid-19, the Telegraph reported.

Health experts are still looking for answers and have called for an urgent investigation. They believed that the pandemic response, lack of access to healthcare, and even the cost of living crisis might be to blame.

“Before the end of March, deaths in England and Wales were lower than usual this year despite hundreds of people dying from Covid. Yet in the last three months, the situation has reversed, with overall deaths rising even though Covid deaths have been falling,” the news outlet added.

We’ve reached the excess deaths are on the rise but not because of covid stage of the pandemic Excess deaths are on the rise – but not because of Covid
— Frank Grimes Jr. (@FrankGrimes_Jr) July 6, 2022

More from Telegraph:

‘The reality is going to be quite complex’
Prof Paul Hunter, professor in medicine, at the University of East Anglia, said some of the excess could be people whose health was weakened by Covid. The infection is known to increase the risk of stroke and heart attacks. But he warned that there may be other more complex factors at play.
“Some might also be down to other impacts of the pandemic, such as problems in accessing health care, delayed referrals for treatment and then things related to the restrictions we lived under, such as reduced activity and sedentary lives,” he said.
“I think the reality is going to be quite complex but it’s something we do need to be aware of and actually try and understand.
“We know there is a relationship between excess deaths and deprivation so maybe the current financial situation we are in is exacerbating that.
“There is despair from your livelihood disappearing up the swanny. It doesn’t have to lead to suicide, chronic stress can lead to all sorts of problems.”
Dr Charles Levinson, the chief executive of the private GP company DoctorCall, also called for a government inquiry into what was causing so many deaths at home.
The ONS reported 752 excess deaths in the home in the latest week, 30 per cent more than usual, and more than hospitals and care homes put together.
“This is exactly why a proper government investigation is required,” he said. “This is not just displacement from hospitals… I do not understand how this is not being properly discussed.”
Dr Levinson added: “The reasons behind these horrific numbers are complicated and none of us fully understand them, so that is exactly why there should be an urgent and comprehensive Government inquiry.
“If anything, the situation seems to be worsening. Considering the relentless focus on one virus for more than two years, requesting answers from Government on thousands and thousands of non-Covid excess deaths is entirely reasonable.”

The Gateway Pundit previously reported that there has been a shocking spike in unexplained deaths reported in the past year among teenagers and young adults.

Below is the list of articles reported by so-called health experts to explain the recent spike in “Sudden Arrhythmic Death Syndrome” (SADS).

Notice what DIDN’T make the list!

The US Sun: Urgent warning to gardeners as soil ‘increases risk of killer heart disease’
  • “Medics found that pollutants in the soil could have a ‘detrimental effect on the cardiovascular system’. Writing in Cardiovascular Research, a journal of the European Society of Cardiology, the authors said soil pollutants include heavy metals, pesticides, and plastics. They state that contaminated soil could then lead to increasing oxidative stress in the blood vessels, which in turn leads to heart disease. Dirty soil can get into the blood stream, through inhalation.”
Daily Mail: Expert warns that shoveling snow can be a deadly way to discover underlying cardiovascular conditions as straining the heart with physical activity could cause sudden death
  • “Dr John Bisognano, head of preventive cardiology at the University of Michigan Health Frankel Cardiovascular Center, warned that people who live stagnant lives could end up straining themselves to the point of death while shoveling snow. ‘Many people haven’t done a lot of exercise for the rest of the year and shoveling snow is not only a heavy exercise, but an exercise that really stresses the entire cardiovascular system,’ Bisognano said in a university release.
Wales Online: Energy bill price rise may cause heart attacks and strokes, says TV GP
  • “A doctor has warned that today’s huge hike in gas and electricity prices for 22million homes across the Uk could mean a rise in heart attacks and strokes. Dr Amir Khan spoke out on ITV’s Lorraine this morning, as he fears the huge new bills will have a devastating effect on people’s health. As a doctor, he said he knows he will see the effects on patients attending his GP practice.”
Wales Online: Sweating more than usual and at night could be a sign of heart attack
  • “Sweating more than usual could be a sign of an impending heart attack, experts say. Night sweats are also a sign for women that they have heart issues. It’s well-known that heart attacks can be life-threatening and the sight of someone in a TV drama clutching their chest as they struggle for breath is a common one. However, in real life there are several early warning signs to be aware of.”
Health Line: Can Snoring Lead to Heart Failure?
  • “Snoring is not only a noisy nuisance — it may also be a sign of sleep apnea. Not everyone who snores has this underlying condition. For those who do, snoring can lead to heart failure.”
CBS News: Watching less TV can reduce heart disease risk, research suggests
  • “A new study finds that if we could limit our daily television viewing, we could reduce our risk of heart disease. They found that people who watched more than four hours of TV a day were at the greatest risk of developing heart disease while those who watched less than an hour of TV a day had a 16-percent lower rate. Interestingly, time spent using a computer did not appear to influence heart disease risk.”
Daily Mail: Entirely new kind of ‘highly reactive’ chemical is found in Earth’s atmosphere – and it could be triggering respiratory and heart diseases and contributing to global warming, scientists claim
  • “Scientists have detected a new type of extremely reactive substance in the Earth’s atmosphere that could pose a threat to human health, as well as the global climate. The research team claims that the hydrotrioxides are likely to be able to penetrate into tiny airborne particles, known as aerosols, which pose a health hazard and can lead to respiratory and cardiovascular diseases.”
The US Sun: Summer holidays warning as flight delays increase risk of silent killers
  • “Experts have now warned that the stress that builds up due to travel issues could be putting you at risk of silent killers. Superintendent pharmacist Abbas Kanani at ChemistClick said unexpected events such as grounded flights and refund issues could trigger physical changes in the body. He explained: “Holidaymakers deciding to sleep in airports, buy unhealthy meals and increase the consumption of alcohol when faced with continuous uncertainty could be at risk of high cholesterol which can lead to the life threatening condition, heart disease.”
Toronto Sun: Daylight savings may increase chance of heart disease, strokes: Studies
  • “Scientific research has found that the transition to daylight saving time, could be linked to heart disease and strokes, according to a report from the American Heart Association.”
New Scientist: Taller people may have a higher risk of nerve, skin and heart diseases
  • “Being taller may increase your risk of developing nerve, skin and some heart diseases, according to the largest study linking height and disease to date. The findings suggest that height could be used as a risk factor to prioritise screening tests for those at greatest risk of certain diseases.”
News Medical: Neighborhood ‘redlining’ may increase risk of cardiovascular diseases
  • “The historical discriminatory housing policies known as “redlining” are associated with heart disease and related risk factors today in impacted neighborhoods, more than 60 years after they were banned, according to a study published today in the Journal of the American College of Cardiology. Health disparities have been linked to a variety of socio-economic, environmental and social factors, and this study adds to growing evidence of the long-term cardiovascular impacts disparities can have on vulnerable populations.”
Medical News Today: What is the link between cold weather and heart attacks?
  • “Cold weather exposure can increase the risk of cardiac responses, including heart attacks. This is because blood vessels respond to low temperatures by constricting, which increases blood pressure and reduces circulation, putting strain on the heart.”
New York Post: Falling asleep with the TV on could bring early death: study
  • “Millions of Americans fall asleep each night in front of the TV — but a new study has found the practice could contribute to an early death. Researchers at the Northwestern University School of Medicine examined the impact of ambient light on the health and sleeping habits of 552 people between the ages of 63 and 84.”
New Scientist: Solar storms may cause up to 5500 heart-related deaths in a given year
  • “Solar storms that disrupt Earth’s magnetic field may cause up to 5500 heart-related deaths in the US in some years. The sun goes through cycles of high and low activity that repeat approximately every 11 years.”
Express: Blood clots: How do you sleep? One position may increase the risk of deep vein thrombosis
  • “Harvard Health writes: “Sleeping sitting up in a recliner […] could in some cases raise your risk of deep vein thrombosis. A blood clot in a limb can occur if your arms or legs are both bent motionless for hours. “But provided you are comfortable and can recline back slightly, there should be few risks to sleeping upright, assuming it doesn’t interfere with your ability to get a good night’s sleep.” Sleeping upright is not the only sleeping position with health risks, however. According to experts at Mayo Clinic, sleeping on the back can cause the tongue and jaw to slant down, crowding the airway.”
 

Heliobas Disciple

TB Fanatic
View: https://www.youtube.com/watch?v=7f45S6vmQgA
Non covid excess deaths
18 min 31 sec
Jul 6, 2022
Dr. John Campbell


Why are people dying more than normal? UK, excess deaths https://www.telegraph.co.uk/news/2022... Hundreds more people than usual are dying each week in England and Wales Not from Covid https://www.ons.gov.uk/peoplepopulati... Covid deaths, UK w/e 24 June, 346 w/e 17 June, 309 Total deaths registered in the UK 12,278 15.9% above the five-year average Latest breakdown, (England and Wales) Excess deaths = 1,540 Covid deaths, 285 58.2% of this 285 gave covid as the underlying cause So, 166 from covid 119 with covid Non covid excess deaths, 1,540 – 166 = 1,374 https://www.ons.gov.uk/peoplepopulati... https://www.ons.gov.uk/peoplepopulati... England and Wales data (5 years up to 2019) England and Wale, 16.6% Wales, 18.2% Where excess deaths occurred (above the five-year average) Private homes, 31.5% above Hospitals, 12.1% above Care homes, 10.3% above Other settings, 10.1% above Health experts call for urgent investigation Pandemic response Lockdown and restrictions stress Reduced physical activity Lack of access to healthcare Delayer referrals for diagnosis and treatment Cost of living crisis People whose health was / is weakened by covid Known increase risk of stroke and heart attacks Vaccination Increasing autoimmune disease New medications used as covid treatments Prof Paul Hunter, University of East Anglia I think the reality is going to be quite complex but it’s something we do need to be aware of and actually try and understand. There is despair from your livelihood disappearing up the swanny. It doesn’t have to lead to suicide, chronic stress can lead to all sorts of problems. Dr Charles Levinson, DoctorCall The reasons behind these horrific numbers are complicated and none of us fully understand them, so that is exactly why there should be an urgent and comprehensive Government inquiry. If anything, the situation seems to be worsening. Considering the relentless focus on one virus for more than two years, requesting answers from Government on thousands and thousands of non-Covid excess deaths is entirely reasonable. User guide to mortality data https://www.ons.gov.uk/peoplepopulati...
 

Heliobas Disciple

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View: https://www.youtube.com/watch?v=MPIaM7yPeMQ
No, BA.5 Does NOT Cause More Severe Disease Than BA.1 or BA.2
44 min 32 sec
Streamed live 7 hours ago
Drbeen Medical Lectures


No, BA.5 Does NOT Cause More Severe Disease An article written in a commercial online site has presented a set of in-vitro studies to demonstrate that BA.4 and BA.5 are more severe than BA.1 and BA.2. Let's review the data. If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/
 

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Study shows increase in COVID-19 vaccine acceptance around the world
by CUNY School of Public Health
July 6, 2022

COVID-19 vaccine acceptance increased 3.7% between 2020 and 2021, according to a new study from researchers at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), the Barcelona Institute for Global Health (ISGlobal), the Dalhousie University and the University of Calgary.

In a June 2021 survey of over 23,000 individuals across 23 countries, the researchers found that more than three-quarters (75.2%) of respondents reported vaccine acceptance, up from 71.5% one year earlier.

The study, which was published Monday in Nature Communications, was carried out within the context of a year of substantial but very unequal global COVID-19 vaccine availability and acceptance, which necessitated new assessments of the drivers of vaccine hesitancy and the characteristics of people not vaccinated.

Concerns about vaccine safety and efficacy and mistrust in the science behind vaccine development were the most consistent correlates of hesitancy. Other factors associated with vaccine hesitancy varied by country and included personal experience with COVID-19 (e.g., sickness or loss of a family member) and demographic characteristics (e.g., gender, education, and income).

The authors found that vaccine hesitancy did not significantly correlate with a country's current COVID-19 case burden and mortality. In June 2021, vaccine hesitancy was reported most frequently in Russia (48.4%), Nigeria (43%), and Poland (40.7%), and least often in China (2.4%), the United Kingdom (UK) (18.8%), and Canada (20.8%).

"In order to improve global vaccination rates, some countries may at present require people to present proof of vaccination to attend work, school, or indoor activities and events," says CUNY SPH Senior Scholar Jeffrey Lazarus. "Our results found strong support among participants for requirements targeting international travelers, while support was weakest among participants for requirements for schoolchildren."

Support for vaccine mandates was substantially lower among those who were hesitant to get vaccinated themselves. "Importantly, however, recommendations by a doctor, or to a lesser extent by an employer, might have an impact on a respondent's views on vaccination in some countries," said CUNY SPH Dean Ayman El-Mohandes.

Although some countries are currently disengaging from evidence-based COVID-19 control measures, the disease has by no means been controlled or ended as a public health threat. The authors note that for ongoing COVID-19 vaccination campaigns to succeed in improving coverage going forward, substantial challenges remain. These include targeting those reporting lower vaccine confidence with evidence-based information campaigns and greatly expanding vaccine access in low- and middle-income countries.

The role of social networks

ISGlobal and the Institute #SaludsinBulos, together with the Severo Ochoa Foundation and representatives of Spanish scientific and professional societies and patient associations, held a meeting on 20 June 2022 to advance the development of a consensus on addressing vaccine hesitancy. According to data presented from a European survey carried out by the Vaccine Confidence Project, the population group most exposed to social networks—young people under 24 years of age, with secondary or university studies and living in urban areas—are the most reluctant to be vaccinated. Additionally, messages that call for vaccination as a "moral obligation" are strongly rejected compared to those that call for "protection," which are more commonly well received.

As reflected in similar studies, one of the most popular ways of conveying anti-vaccine messages has been humor. Therefore, participants in the meeting agreed on the need to disseminate the benefits of vaccines using this same tool, but without making fun of those who have mistaken beliefs about vaccines. In the face of misinformation, it is important to improve information on vaccination using simple language and channels that reach the population, such as social networks, the participants concluded.
 

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How omicron dodges the immune system
by University of Geneva
July 6, 2022

By comparing the neutralization capacity induced by the different variants of SARS-CoV-2, a team from the UNIGE and the HUG reveals the exceptional capacity of omicron to evade our immunity.

The current wave of COVID-19 highlights a particularly high risk of reinfection by the omicron variant of SARS-CoV-2. Why is this? A team from the Center for Emerging Viral Diseases of the University of Geneva (UNIGE) and of the Geneva University Hospital (HUG) analyzed the antibody neutralization capacity of 120 people infected with the original SARS-CoV-2 strain, or with one of its alpha, beta, gamma, delta, zeta or omicron (sub-variant BA.1) variants. And unlike its predecessors, omicron appears to be able to evade the antibodies generated by all other variants. In vaccinated individuals, while the neutralization capacity is also reduced, it remains far superior to natural immunity alone. This could explain why omicron is responsible for a net increase in vaccine break-through infections, but not in hospitalizations. These results can be read in the journal Nature Communications.

Since the beginning of the pandemic the HUG outpatient test center offers SARS-CoV-2 testing for the community. "As a national reference center for emerging viral diseases, we have the capacity to sequence a large proportion of positive cases to monitor the appearance of new variants," explains Isabella Eckerle, professor in the Department of Medicine at the UNIGE Faculty of Medicine and head of the HUG-UNIGE Center for Emerging Viral Diseases, who led this work. "Since the beginning of 2020, we have collected samples of the original virus and all its variants that appeared in Switzerland, even the rarest ones such as gamma or zeta. This makes it a comprehensive collection of samples from individuals with different infection backgrounds, collected according to an identical protocol."

The research team took blood samples from 120 volunteers previously infected with one of the different variants, unvaccinated, or vaccinated and infected, either before or after vaccination. "With a mean age between 28 and 52 years, without major co-morbidities and a mild to moderate form of COVID-19, this cohort represents the majority of cases in the community," Isabella Eckerle explains.

Antibody levels ten times higher with vaccination

The aim was to determine how well the antibodies generated during the first infection were able to neutralize the different variants of SARS-CoV-2. "Omicron proved to be the most effective at evading pre-existing natural immunity, as well as, to a lesser extent, that induced by vaccination," explains Benjamin Meyer, researcher at the Center for Vaccinology at the Department of Pathology and Immunology of the Faculty of Medicine of the UNIGE. Indeed, antibody levels against ancestral SARS-CoV-2 in vaccinated people are roughly 10 times higher than in people who have only developed post-infection immunity. Moreover, the combination of the two, known as hybrid immunity, seems to maintain even higher and broader reactive antibody levels.

"Thus, omicron can evade existing immunity and cause an infection, but hospitalization and death due to COVID-19, even with Omicron, is still reduced after vaccination." Nevertheless, SARS-CoV-2 retains an astonishing ability to mutate, which also appears to be accelerating. "Vigilance is still required, especially as the epidemiological curves have been rising sharply since the appearance of BA.5, the most recent omicron sub-variant," adds Isabella Eckerle.

The scientists also performed antigenic mapping of the different variants, based on the same model used to determine the antigenic changes of influenza. "This computational method makes it possible to represent the distance between the characteristics of the antigens of the variants concerned: the further away they are, the less effective the antibodies generated during previous infections will be. It turns out that the omicron serotype is totally different from the others, as was the zeta variant, which disappeared rapidly," reports Meriem Bekliz, a post-doctoral researcher in Isabella Eckerle's lab and first author of this study.

Advances in virus understanding

Never before has a respiratory virus been scrutinized so closely. "This virus, which belongs to the same family of coronaviruses that cause almost a third of common colds, can, in the absence of measures, spread like wildfire in populations with no immunity to fight it," explains Benjamin Meyer. "We now have sequencing and molecular observation tools that were unknown a few years ago; the discoveries we are making today open up perspectives and understanding that will be useful far beyond SARS-CoV-2."

The COVID-19 pandemic has also allowed an unprecedented acceleration in vaccine research. Several teams are now working on nasal spray vaccines, which are easier to administer and, above all, can act directly in the mucous membranes of the nose and throat, where they are most useful.
 

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Messenger RNA technology shows promise for developing infectious disease therapeutics
by US Army Medical Research Institute of Infectious Diseases
July 6, 2022

Army scientists and industry partners were among the first to demonstrate that messenger RNA (mRNA)—the technology recently used in COVID-19 vaccines and others—could also be used to develop treatments for infectious diseases. Their work appears in the June 2022 issue of the journal Molecular Therapy Nucleic Acids.

Investigators at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) collaborated on the study with scientists from CureVac, a biopharmaceutical company focused on developing a new class of drugs based on mRNA. Their central principle is to use mRNA as a data carrier for information that the body can use to produce its own therapeutic, effectively warding off disease.

The team set out to examine the capabilities of nucleic acid technology apart from vaccine development. To demonstrate proof of concept, they used several mRNAs carrying the "blueprint" for three separate monoclonal antibodies (mAbs)—proteins that help to produce an immune response. According to the lead author Eric Mucker, Ph.D., when the mRNAs were administered to the same rabbit, all three mAbs were shown to be circulating in the blood within just one day.

"We are pleased that with this project we were able to show, for the first time, significant systemic levels of functional antibody transcribed from an mRNA upon intramuscular injection," said Patrick Baumhof, Senior Vice President for Technology at CureVac. "The possibility of simultaneous expression of three distinct antibodies within the same animal shows the potential of mRNA antibody technology."

The work was supported by the Defense Advanced Research Projects Agency's ADEPT: PROTECT program, which is aimed at early detection and rapid response to disease outbreaks.

"This study and similar projects conducted under the ADEPT: PROTECT program were truly innovative," said Mucker, adding that they effectively laid the groundwork for mRNA vaccines years before the COVID-19 pandemic.

Notably, the three mAbs tested in the study also had previously demonstrated some potential activity against poxviruses—making the publication of this work especially timely in light of the simultaneous monkeypox outbreaks occurring around the world.

"USAMRIID has an extensive track record for developing models, tools, and countermeasures to combat smallpox and monkeypox diseases," commented USAMRIID senior author Jay Hooper, Ph.D. "While this study is primarily technology based, it specifically contributes to future-generation countermeasures to prevent and treat diseases caused by pathogenic poxviruses."
 

Heliobas Disciple

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My Rather Public Reply To The Threat Made Against Me By The American Board Of Internal Medicine
I published an Op-Ed to defend from the attacks by State Medical Boards and National Certifying Bodies against experts whose opinions conflict with numerous, demonstrably false "Covid Narratives."
Pierre Kory, MD, MPA
10 hr ago

A month ago, I received a letter from the American Board of Internal Medicine accusing me of spreading misinformation and threatening to revoke my certification based on their new policy “against misinformation.” I initially laughed and tossed it into a pile of papers, dismissing it as just the latest in a string of (non-evidence based) attacks on me from.. well, everywhere. I will include the letter and my Op-Ed response to it below.

First, for the non-doctors among my subscribers (many of you?), you probably need a quick primer as to the differences between “Licensing” Boards and “Certifying” Boards in Medicine.

To practice medicine in the United States, you first need to be licensed by a State Medical Board (not done at the Federal level thank God). Meaning, when you graduate from medical school and then complete a “residency” training program, you can apply for a license to practice medicine in the state where you will be caring for patients. Fun fact: the word “residency,” which describes the apprenticeship model of training after medical school (typically lasting 3-8 years depending on specialty), is called that because physician “apprentices” literally used to live and work in the hospital 24-7, i.e. they were “residents” of the hospital!

Anyway, most doctors see patients in only one state and thus one state license is all you need. If you want to see patients in more than one state (like many Tele-Health practices do), you have to apply for multiple state licenses which cumulatively can add up to a fortune. A fun fact that I discovered while applying for licenses to expand my COVID and Vaccine Injury Tele-Health practice: Louisiana charges $250 for a license for 2 years while California asks for $1500. Clown world.

Now, before we get to the ABIM letter, let’s first talk about what is happening at my state medical licensing board which actually has the authority to revoke my license. That Board has relayed to 11 different complaints they received, but not one was from a patient. All were from anonymous doctors, pharmacists, and laypeople complaining to them that I disseminate mis-information around ivermectin. My responses to these ill-informed complaints were almost fun to write as it was like shooting fish in a barrel with a machine-gun of data. I am still waiting to hear of my punishment but my sense (hope) is that there will be nothing substantive. One of my many defenses was citing the increasing number of states passing legislation to protect doctors who use repurposed medicines from such Board actions. However, although I have multiple state licenses, if one state revokes your license, you have to inform the others, and they might follow suit.
Ugh.

So, what is the American Board of Internal Medicine (ABIM) then? The ABIM is a “Certification” Board, with their certification purportedly denoting a higher level of knowledge and skill than the supposedly “average,” non-Board certified physician. To achieve this distinction, all you need to do is pay an increasingly obscene Board exam fee and then pass the test. It should go without saying that these tests have high passing rates. Anyway, pass the test, and voila, you become “Board Certified.” It gives off an appearance of higher credibility so you can introduce yourself or be introduced with, “Dr. Kory is Board Certified in Internal Medicine, Pulmonary Disease, and Critical Care Medicine.” It also helps when you serve as an expert witness in malpractice cases, such as when I was the expert witness in the George Floyd civil suit (I definitely would not have been selected if I was not Board certified - the opposing lawyer would have been able to present me in an unfavorable light as a result).

Fun fact: When I was becoming an expert in critical care ultrasonography, I studied, paid for, and passed the National Board of Echocardiography Exam, but I did not receive a board certification from them because… they would not bestow that on a non-cardiologist! They instead granted me “Testamur” status, a word meaning witness. I “witnessed” the exam I guess. Whatever. Another fun fact is that at the time I was one of the very few non-cardiologists who had ever taken, let alone passed the exam. Two reasons for that; one is that nobody outside of cardiology ever tried to learn echocardiography to that extent (I studied and practiced obsessively for months) and second is that it was a notoriously difficult exam with around a 65% passing rate even among cardiologists. That is why the absolute joy I felt when I received the letter telling me I passed was not one bit lessened when I discovered I had literally passed the exam… by one correct answer.

Anyway, every physician specialty and sub-specialty has one of these “Certifying” organizations which perform increasingly deeper wallet biopsies over time. All these boards are governed under the umbrella of the American Board of Medical Specialties (ABMS), a.k.a El Capo de Tutti Capi. The ABIM itself only certifies adult medical (not surgical) specialties, i.e. cardiology, pulmonology, gastroenterology, rheumatology etc. Note that internal medicine is just one of the “5 families” that physicians belong to, i.e. Internal Medicine, Surgery, Pediatrics, Psychiatry, and Ob-Gyn.

Recently, when the ABIM added more costly and burdensome requirements beyond the exam, doctors across the country revolted and brought a class action lawsuit. They argued that the ABIM was a monopoly extorting money out of physicians purportedly with the goal of improving knowledge and skill but without evidence that it was actually accomplishing that. The suit actually argued that the ABIM's MOC program was designed chiefly to produce revenue for their board as detailed in this article by the investigative journalist and Pulitzer prize finalist Kurt Eichenwald. Further, they fought the ABIM because increasing numbers of health insurance companies and health systems began requiring doctors to be “Board Certified” in order to be employed or part of a health insurance network. Hence the feeling of being extorted by a monopoly power.

Anyway, when I laughed at the ABIM letter, it was because I am now in private practice where I am my own boss and I don’t (can’t) take insurance so losing my Board Certification would have zero negative impact on my ability to care for patients. However, it started to slowly dawn on me that if they took away my ABIM Certification, I might not be able to work in an ICU again (not that I see that happening until the system comes to its senses). So maybe it isn’t so funny. Kind of like everything else going on in the world.

Anyway, here is the ABIM letter to me followed by my Op-Ed published in RealClear Politics (note I wrote the Op-Ed before starting work on my “official” response letter).








My favorite part of the letter is on the last page where they promise me that after they sanction me (strip me of my certification?), I will get to appeal… in a hearing with a panel of physicians! Bring. It. On.

I also have to laugh because I am picturing Steve Kirsch burning with jealousy over this opportunity. He has been trying to get someone, anyone from medical academia or the health agencies to come out from behind closed doors and participate in an open scientific debate of the data (not) supporting the “safety and efficacy” of the mRNA vaccines. He has even been offering experts $1 million to do so.. and they have all refused. Well Steve, looks like I get to participate in one of those debates for free!

Now, my Op-Ed:

Stop the War on Doctors
By Pierre Kory
July 02, 2022

Anyone in America who deviates from the group-think enforced by public health bureaucrats runs the risk of cancellation. Politicians, parents, comedians, teachers – now they’re even coming for the doctors.

As a lung and ICU specialist, I have practiced medicine for 14 years and successfully treated more than 450 patients during the pandemic. Long before anyone had heard of Covid-19, I was studying and implementing cutting-edge methods to treat critically ill patients. I’m the Senior Editor of a best-selling textbook in my field, now in its second edition, which has been translated into seven languages.

For my efforts, I now find myself on the receiving end of “disciplinary sanctions” from the American Board of Internal Medicine (ABIM), who sent me a letter threatening “suspension or revocation of board certification.”

The “sin” threatening to end my medical career was my unwillingness to go along with Fauci’s monolithic vaccines-above-all-else strategy. The failure of this approach is plain to see, and anyone with an ounce of curiosity knows there are many methods of treating the virus.

Ivermectin is one of them. This cheap, readily available generic medicine is approved by the FDA for certain uses in humans – but not for Covid-19, despite 85 controlled trials from around the world demonstrating its effectiveness. In Brazil, the largest study to date found a reduction in Covid mortality rate of 70%. In India, the second most populated country in the world, the drug has been credited with near eradication of the disease. Studies attempting to discredit ivermectin have been debunked again and again.

Other trials, such as the recent TOGETHER trial, are designed to fail from the start to drive a desired narrative. In the National Institutes of Health’s ACTIV-6, despite starting the majority of patients on treatment after five days of Covid-19 symptoms at a lower than recommended dose, they found a statistically significant reduction in the time to recovery, particularly among the most severely ill. Unsurprisingly, major newspapers reported that the study showed ivermectin was ineffective.

Despite ivermectin’s proven effectiveness, in the opinion of the ABIM, advocating for its usage is a form of “disinformation” and carries the penalty of losing one’s medical license and livelihood.

Throughout the pandemic, I’ve maintained an open mind, analyzed what works for patients, discussed strategies with fellow doctors, and conducted my own extensive research. When new data arose that changed my understanding, I admitted as much and changed course—like with the vaccines. If only the powers that be at the ABIM and our government could say the same.

Consider the evolution of accepted facts about Covid-19 safety measures from Fauci and his ilk. Despite government mandates, neither lockdowns nor cloth masks prevent transmission. They never have. It turns out former Surgeon General Jerome Adams had it right when he tweeted in March 2020 that masks are, “NOT effective in preventing general public from catching #Coronavirus” – a comment for which he was pilloried. We are only beginning to learn the impact of the societal costs of these early preventative measures, a price our children who were kept home from school will be paying for years.

Second, there is no evidence the vaccines stop Covid-19, despite the constant lecturing from the Biden Administration and the mainstream media. In the United States and globally, cases continue to rise and fall without any correlation to the pace or percentage of population vaccinated. This is not what we were promised. In 2021, Fauci said vaccinated people were “dead ends” for the virus, and President Biden declared, “You’re not going to get COVID if you have these vaccinations.” Today, approximately 110,000 cases are announced daily in America, where more than two thirds of the population is fully vaccinated.

There is a backlash brewing in America right now, and it goes beyond inflation rates and gas prices. People are tired of arrogant public officials and compromised institutions who believe they have all the answers but constantly get it wrong and make no apologies as they steamroll those who don’t support the current narrative. The ABIM’s sudden (and suspiciously well-funded) persecution of doctors who stray from the party line is only the latest example.

Doctors on the ABIM’s board and across the country need to stand up against this witch hunt. It’s demeaning to honest doctors and dangerous to the patients we’ve dedicated our careers to serving.

Pierre Kory, M.D., is president and chief medical officer of the Front Line COVID-19 Critical Care Alliance.

I just want to say how much I appreciate all the subscribers to my substack, and especially the paid ones! Your support is so greatly appreciated.

P.S I opened a tele-health clinic providing care not only in the prevention and treatment of acute COVID, but with a specialized focus on the study and treatment of both Long-Haul and Post-Vaccination injury syndromes. If anyone needs our help, feel free to visit our website at www.drpierrekory.com.
 

Heliobas Disciple

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"A Peasants Revolt"
FDA and the CDC are on Notice/The Casket Industry is Booming
Etana Hecht
15 hr ago

Caskets

I spoke to the family who owns one of the largest casket manufacturers in North America. They supply caskets to huge chains across the US and manufacture Prime Caskets, among others. It’s horrific to have to report on such a thing, but the owners said that their sales of typical caskets have increased by 20%, and since Dec 2021 their sales of small-size caskets (under 5 feet, i.e, for children) have increased by 400%. He’s not the only one talking about it, those in the funeral industry are well aware of the sudden change in the nature of their business.


For the first time in over 30 years in business, they’ve begun to receive orders for small-size caskets in bulk. That sentence makes me nauseous to type, so armed with that painful piece of information, let’s focus on the tremendous efforts to keep the kids healthy. Of course, the casket numbers themselves aren’t proof that the vaccine is harmful or fatal for some children, but it sure is yet another blaring red signal.

On Offense

Dr. Naomi Wolf appeared on Warroom and announced some positive developments in the efforts to save children from the Covid vaccines, amidst a flurry of activity as the responses to the FDA authorization of Covid vaccines for babies ramp up. As Steve Bannon put it, this should be a “peasant’s revolt against the administrative state”, and thanks to the efforts of Daily Clout and its supporters, along with other amazing grassroots organizations, that’s exactly what’s happening.


Link to Video

11 min 27 sec


“A Shot Across the Bow”
: Dr. Naomi Wolf of Daily Clout and the Health Freedom Defense Fund fund filed a citizen’s petition with the FDA to request a reversal or suspension of their EUA for Covid-19 vaccines for children. They requested attention for the more than 130,000 comments regarding the EUA that were submitted by the public. Scott Street and John Howard are among the attorneys who successfully put a stop to the forced masking on airplanes, to the huge relief and gratitude of millions of people. They’re now representing Daily Clout and the HFDF in the efforts to end the Covid vaccines for children.

The letter included a part from Dr. Naomi Wolf herself, where she notes the negligible risk of Covid-19 for children and the fact that neither safety nor efficacy has been proven for the vaccines. Healthy kids are more at risk from seasonal flu than Covid, and there’s no justification to expose the kids to the known and unknown risks of an experimental vaccine. The letter ended with a fantastic line from the lawyers:

“The FDA is charged with protecting public health, not marketing the products of arguably the most powerful industry in the world”



The entire petition can be read here, and a summary by the HFDF can be read here.

Additionally, The Children’s Health Defense has also served a legal letter to the FDA to halt the children’s Covid-19 vaccine.

These letters serve as a warning shot to the health agencies that if they don’t do as the petition requests, there will be legal action taken. The pressure is most definitely mounting as each of these actions creates another chink in their bureaucratic armor.

Remdesivir in Oklahoma: The Daily Clout legal team sent a letter to Ascension Health Group informing them that they’re on notice to stop using Remdesivir due to the data that shows it’s killing people, along with a request to research therapeutics.

CDC On Notice: Oregon State Senators Kim Thatcher and Dennis Linthicum along with Dr. Henry Healy have officially received a response from the CDC regarding their notification of a demand for a grand jury investigation. The response was negative as expected, but the response triggered a 60-day timeline for the CDC to take substantive action, or the next stage toward a grand jury investigation will advance.

A Demand for Answers: Administrative Judge Alejandro Recarey is a judge in Uruguay. As reported by Rio Times Online, an official complaint was filed to request an injunction of the children’s Covid vaccinations, a request that they are immediately suspended. In response, Judge Recarey ordered that the government health agencies, as well as Pfizer, must appear in by today, Wed July 6 at 9:00 AM and provide answers to the following questions, among others:
  • Contracts between the Uruguayan government and Pfizer. Included in that must be any information regarding compensation for victims of side effects.
  • Information about how the vaccine batches were distributed, and what quality control measures are taken.
  • “Detailed information on the biochemical composition of the vaccine – including whether graphene oxide and nanotechnology components are included”
  • Evidence that the mRNA they used is harmless.
  • A definitive statement on if any part of the vaccine, or the vaccine itself is experimental.
  • Data showing the safety and efficacy of the vaccination.
  • Information about the average age of “Covid-19 deaths” and how many of those had co-morbidities.
  • Information about what, if any, studies are being done to investigate an increase of deaths in Uruguay from March 2021.
  • Scientific evidence that unvaccinated people pose a risk.
  • Information on connections that exist between the people who are the driving force behind the vaccine campaign, and pharmaceutical companies or NGOs.
  • Information on how thoroughly alternative therapies against covid-19 have been researched and considered.
All eyes on Latin America!
.
 

Heliobas Disciple

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A few notes on Ba.4 and Ba.5
General background on the mutations and the downstream effects.
Modern Discontent
13 hr ago

With Ba.4 and Ba.5 reaching the US there’s been another emergence of hysteria from all sides as to what this would mean, and yet in this context there doesn’t appear to be any information as to what mutations within Ba.4 and Ba.5 we should all be concerned about.

So this seems like a good time to review a bit about Ba.4 and Ba.5 and also examine whether this is something akin to vaccine escape or really just a consequence of a typical viral mutation.

In regards to Ba.4 and Ba.5

Before we begin, for those wanting to find additional information on Ba.4 and Ba.5 I suggest this article from Forbes. Strangely, Forbes has been one of the only mainstream outlets out there that actually includes a good bit of the science know-how in their COVID reporting, although I believe that is likely due to the contributor more than the outlet itself.

Also, yesterday Stephanie Brail of Wholistic posted this new article in the NEJM1 with this nice little mutation lineage of Ba.4 and Ba.5 (the Forbes article also contains a mutation lineage as well). Mutation lineages are an outline as to what mutations a subvariant may contain relative to other subvariants. Here, we can see all of the mutations that arose in all of the Omicron subvariants.

Note that, although Ba.4 and Ba.5 are distinct they appear to be clumped together due to both having similar mutations. Ba.4 and Ba.5 appear to have diverged from the Ba.2 lineage of Omicron and so far only appears to have a few mutations of note within the spike protein:


From Hachmann, et. al. A mutational lineage shows the various mutations across Omicron subvariants relative to Wuhan. Colors indicate which subvariants carry which mutations.

As we can see above there’s about 4 distinct mutations of note here: the addition of the 69-70 deletion that was originally seen with the first strain of Omicron, the L452R mutation, the F486V mutation, and the Q493 reversion. The last one (Q493 reversion) may be the most fascinating of the bunch, as it’s a reversion back to the original glutamine amino acid seen in the prior strains of Wuhan, Alpha, Beta, and Delta.

So we know what mutations differ Ba.4 and Ba.5 from other lineages, the important thing to look at now is to examine what these mutations do and how they may affect neutralizing antibodies.

Before we Begin

In order to look at the relationship between viral mutations and antibodies we first need a bit of a background in amino acids. Amino acids are the building blocks of proteins. Generally there are 20 commonly found amino acids, although there are actually many more that are typically found in the human body.

These 20 amino acids2 are usually grouped by their side chains, which is the structure that differs between all amino acids and confers it’s biochemical properties. These side chains can usually contain a positive charge (as seen with R, H and K below) or they may provide a negative charge (with D and E below). The side chains are the structures shown below the typical amide backbone:


Amino acids derive their functionality from their side chains and how they interact with other amino acids.

Ionic/Electrostatic Interactions

For example, the charged amino acids are an example of opposites attracting, such that positively charged amino acids favor interacting with negatively charged amino acids (R likes D, for instance). This is an example of an ionic interaction and is one of the strongest interactions when it comes to interactions between amino acids.

There are some rare circumstances where two similarly charged amino acids may interact, such as the case for when salt bridges are available. Salt bridges occur when an ionic atom is sandwiched between two amino acids. The amino acids must share a similar charge while the ion must be opposite. An example of this would be a D-Potassium Ion-E salt bridge, such that the two anionic amino acids D and E have a positively charged Potassium Ion (K+) situated between the two amino acids.

This tends to be the most typical viral mutation, which generally swaps one amino acid for another that is ionic in nature, and one that can typically interaction with an oppositely charged amino acid on something such as a receptor.

Hydrogen Bonding

The next favorable interaction is called hydrogen bonding. For the sake of this discussion, we’ll limit hydrogen bonding to discuss amino acid side chains that either contain Oxygen or Nitrogen atoms. Oxygen and Nitrogen sit in an interesting spot on the period table, such that their high electronegativity means that they can both share and receive weak polar bonds made with Hydrogen atoms. When Oxygen or Nitrogen is bonded to a Hydrogen atom, their bond is polar and thus not a full covalent bond. This polarity causes the Hydrogen atom to have a slightly positive charge which can attract other Nitrogen/Oxygen atoms to form their own partial bond to this Hydrogen. Essentially, there’s a shared partnership going on in Hydrogen bond formation.

If A Nitrogen/Oxygen atom is sharing their hydrogen, they are considered to be hydrogen bond donors since they are donating their Hydrogen. Nitrogen/Oxygen atoms who can form bonds to Hydrogen are called hydrogen bond recipients. Although these bond formations are generally weaker than ionic interactions, the overall net effect of many hydrogen bonding interactions occurring is what makes this interaction so strong. It’s essentially the sum of all of its interactions, and the ease of such interactions that makes hydrogen bonds so powerful. When looking at which amino acids can hydrogen bond, remember that hydrogen bonding is possible between ionic amino acids as well as the polar amino acids due to the existence of Oxygen and Nitrogen atoms.


From chemistrylearner.com. Several examples of hydrogen bonding are shown above. Hydrogen bonding occurs between the hydrogen of one molecule and the lone pair of an atom such as Oxygen or Nitrogen. The red dashed line shows the hydrogen bond being formed.

Although there are a few other amino acid interactions, these two are the most important ones for this discussion so we will limit talks to just these two.

Why this Matters

At this point this all may seem trivial are a bit too technical. Remember that science is technical, and in order to understand what is going on one must understand the nuanced nature of science.

Amino acids comprise nearly all living matter- we’re all made up of tons and tons of different proteins, including structural proteins as well as enzymes.

Interactions between amino acids drive biochemical reactions. In the case of viruses, interactions between the amino acids of a virus’ exposed proteins and with our own receptors are what dictates infectivity and pathogenicity of a virus.

Interactions with antibodies- which have paratopes that are amino acid based- and viruses are also dictated by amino acid interactions. Essentially, in order to understand why a virus binds better to a receptor, or why antibodies may lose effectiveness with emerging mutations we must look at the amino acid interaction occurring in order to gain proper insight.

For more, I have written previously on the effects of the N501Y mutation, as well as a bit about the E484K mutation and D614G mutation previously:


Remember to keep all of this in mind when looking at some of the mutations in Ba.4 and Ba.5.

The 69/70 Deletion

So there’s not quite much to discuss in regards to this deletion, mostly because it has appeared in a few of the commonly circulating variants beforehand. This deletion first emerged with Alpha and was found with the first strain of Omicron.
However, other subvariants did not have this deletion until the emergence of Ba.4 and Ba.5.

[continued in next 2 posts]
 

Heliobas Disciple

TB Fanatic
[continued from post above - part 2 of 3]

Because this is a deletion, a loss in antibody binding likely stems from not having the proper epitopes for antibodies to target. Therefore, just the absence of these amino acids is likely to prevent antibodies that target this region from binding.
William Haseltine from the Forbes article posited this remark about this deletion:

There is also a deletion of positions 69 and 70 in the N-terminal domain. This is a common mutation found in natural variants and likely knocks out an antibody binding site, meaning this specific mutation could impact overall immune evasion.

Running counter to the immune escape hypothesis above is a study from Meng, et. al.3, in which the researchers suggest that this deletion does not confer immune escape, but likely emerged along with other mutations as a way to balance out reduced binding affinity to the ACEII receptor:

We find that ΔH69/V70 does not significantly reduce the sensitivity of spike to neutralizing antibodies in serum from a group of recovered individuals or binding of multiple mAbs directed against the NTD. In addition, we have shown that repair of ΔH69/V70 does not appreciably alter the potency of NTD antibodies against the B.1.1.7 spike. Thus, the deletion is unlikely to be an immune escape mechanism. Instead, our experimental results demonstrate that ΔH69/V70 is able increase infectivity of the Wuhan-1 D614G spike PV as well as the PV bearing the additional RBD mutations N439K or Y453F, explaining why the deletion is often observed after these immune escape mutations that carry infectivity cost (Motozono et al., 2021; Thomson et al., 2021).

So this deletion may actually serve as some sort of compensatory mechanism for the virus, although it’s worth noting that Omicron does not carry any mutations within the N439 or Y453, although there is a mutation in the 440 position of the original Omicron strain as well as the L452R mutation of the Ba.4 and Ba.5 sublineages.

In short, the 69-70 deletion has appeared in several variants, and although a deletion would be assumed to indicate immune escape, it also suggests a possible mechanism that makes up for loss of binding from other mutations, highlighting the importance of examining multiple factors when assessing what is actually happening. So for now, it may be premature to suggest that this deletion itself is an indication of immune escape or loss of neutralizing antibody activity.

The L452R Mutation

When reading mutations note that the first letter indicates what the original amino acid was (in this case a Leucine). The middle number indicates which amino acid position carries the mutation (the 452nd amino acid). The last letter then indicates which amino acid is now in that position (in this case the Leucine is replace with an Arginine).

The L452R mutation is a mutation that has emerged quite frequently. For example, this mutation was seen in the Epsilon variant (the variant that emerged in California; B1.427/429) which spread throughout the US until late 2021 alongside Delta, which also carries this mutation. This mutation also apparently emerged from a mink population in Denmark (B.1.1.298), although it was relatively short-lived.

Using the information above, we can look at this mutation and infer what we would expect to occur.

This mutation is from a nonpolar amino acid Leucine to a positively charged, hydrogen bond competent amino acid Arginine. As such, we may expect that these new interactions may confer some greater fitness to the virus.

In one study by Motozono, et. al.4, researchers found that the L452R mutation led to great infectivity and fusogenicity of the virus, likely aiding in the virus’ overall fitness.


From the graphical abstract from Motozono, et. al. Note that at the time of publication Epsilon was gaining in the US, although its dominance was likely superseded by other variants such as Delta and Omicron.

One suggestion for this increased fitness is an interaction between this new positively charged Arginine and various negatively charged amino acids on the ACEII receptor:


From Fig 2. of Motozono, et. al. The 3D structure of SARS-COV2’s spike is shown in white while the 3D structure of the ACEII receptor is shown in dark grey. The right image shows electrostatic mapping, with greater regions of red indicating negatively charged regions while regions with more blue suggest more positive regions. Note that the shift from Leucine to Arginine (from top to bottom) leads to an enrichment of positive charge nearby negatively charged amino acids on the ACEII receptor. This more favorable interaction is suggestion to increase binding affinity.

The researchers note this in their discussion:

In the present study, we demonstrate that at least two naturally occurring mutations in the SARS-CoV-2 RBM, L452R and Y453F, escape HLA-restricted cellular immunity and further promote affinity toward the viral receptor ACE2. We also demonstrate that the L452R mutation increases the stability of the S protein and viral infectivity and thereby enhances viral replication. Our data suggest that the L452R mutant escapes HLAA24-restricted cellular immunity and further strengthens its infectivity. Consistent with our findings, Deng et al. performed a pseudovirus assay and showed that the L452R mutation increases viral infectivity (Deng et al., 2021). However, the mechanism of action was not revealed. Here, we demonstrated that the L452R mutation increases viral fusogenicity.

Similar sentiments were provided in a short study by Zhang, et. al.5:

Compared with parental virus and previous variants, the Omicron variant is characterized by decreased hospitalization rates and less severe disease in patients.2 However, how the Omicron variant reduces pathogenicity remains unclear. The Omicron variant has diminished fusogenicity, although the underlying mechanism is unknown. Fusogenicity was shown to be associated with pathogenicity in SARS-CoV-2 patients.3 The L452R mutation, one of the most frequent mutations (Fig. 1a, b), is the only RBD domain mutation that emerges in the Delta variant but is absent in the Omicron variant (Fig. (Fig.1c).1c). It has been reported that L452R mutation increases SARS-CoV-2 fusogenicity and infectivity.4 Here, we developed an L452R mutated Omicron variant (Omicron-L452R) and found that the Omicron-L452R variant rescued fusogenicity and strengthened the high infectivity by enhancing the cleavage of the spike protein. Notably, Omicron-L452R greatly enhanced the ability of Omicron to infect lung tissues of humanized ACE2 mice. Furthermore, the Omicron-L452R variant dramatically enhanced glycolysis in host cells. Our data suggest that the decreased fusogenicity of the Omicron variant is due to a lack of the L452R mutation present in the Delta variant.

It’s interesting that this additional mutation has likely made Ba.4 and Ba.5 behave similar to Delta. Remember that Delta was considered to be more virulent compared to prior strains, and thus this does raise a few concerns as to whether this mutation may make Ba.4/Ba.5 infection more severe.

What’s important for the layperson may be how this affects prior immunity. As can be seen in the mutational lineage above, the L452R mutation occurs in the Receptor Binding Domain (RBD) of the spike protein. More specifically, it’s part of the Receptor Binding Motif (RBM). The RBM is the actual point of contact between the spike protein and the ACEII receptor.

Usually, these regions serve as double-edged swords: if a virus mutates to gain a fitness advantage, this mutation may carry this strain of the virus forward and allow it to propagate further. However, if a mutation arises that reduces binding affinity, this strain would likely be less fit and thus eventually die out.

Remember that the story of variants is a story told by the victor. We only hear of variants with greater fitness because those that have mutated to be less fit will die off, never to be heard from again.

With that being said, most antibodies target the RBD of the spike protein and elicits neutralizing capabilities. However, if the sequence in the RBD mutates antibodies are likely to lose their binding abilities. Generally speaking, mutations in the RBD are usually the main reason why antibodies no longer bind or neutralize a virus. On that note, we can infer that the placement of this mutation is likely to play a role in reduced neutralization.

However, considering that this mutation was also seen in both Epsilon and Delta, it does raise questions as to whether people infected during this timeframe actually have antibodies that target epitopes containing the L452R mutation, which would suggest that these people may be more protected against Ba.4 and Ba.5 relative to other individuals.

This possibility is made very unclear, mostly because many people are unaware of which variant they are infected with. Paired with lack of information on the longevity and breadth of natural immunity we are somewhat left in the dark as to exactly what antibodies and B/T cell responses would hold up against Ba.4/Ba.5. This is just another problem among a host of other problems where we are left to speculate about possibilities due to lack of investigation by the scientific community.

[continued in next post]
 

Heliobas Disciple

TB Fanatic
[continued from post above and above that - part 3 of 3]

The F486V mutation

This mutation is pretty interesting. It’s a mutation from a nonpolar Phenylalanine (F) to a nonpolar Valine (V). Generally speaking, this mutation that keeps within similar side chain groups may not confer much in the ways of enhanced/reduced pathogenicity. One factor that may be important is the bulky phenyl group that is part of Phenylalanine, and the loss of that group may alleviate some steric hindrance in the protein. However, even with that said general such a slight variation is usually not one to raise many alarms.

In one study by Tsai, et. al.6 researchers used in silico (computer) modeling to see the effects of various RBD mutations on antibody binding.

For F486 they modeled an antibody called MR-17 (an antibody derived from a llama) that interacts with this amino acid (along with other amino acids) to see if mutations within the spike protein would reduce binding to this antibody.


From Tsai, et. al. The modeled interaction between the RBD of SARS-COV2 spike (in green) and an antibody (MR17, in cyan). F486 is boxed in red above.

Interestingly, modeling suggests that the sidechain of F is not responsible for interactions with the antibody, but that the oxygen atom from the amide backbone of F may be responsible for interacting with R residues on the antibody.


A diagram outlining the possible interactions between F486 of the spike protein and the R59 residue of the M17 antibody. It is suggested that the Oxygen (in red) from the amide functional group of F486 is what is responsible for interacting with R59 via a dipole interaction.

Heatmap analyses generally showed that any mutation away from Phenylalanine to other amino acids led to reduced binding stability to the M17 antibody. These results are rather strange, considering that for various heatmaps provided even mutations towards a Tyrosine or Tryptophan residue suggests that these mutations are unfavorable for binding to antibodies. All but one heatmap (Foldx) showed reduced antibody association while the heatmap from Foldx showed an increased association if Phenylalanine was changed to Valine. All of this is likely a consequence of in silico analyses which are likely to produce highly variable results due to whichever variables are added to the computational algorithm. Or, it could be due to the more malleable nature of the M17 antibody as compared to the ACEII receptor.

Keep in mind that this study only provides a very narrow window into the role of this F486 mutation and immunity escape. It doesn’t tell us what interactions may occur with human antibodies, and whether this slight change may alter anything significantly.

In short, this mutation is likely to be the least of the concerns here, since the F486V mutation is not one to drastically change the behavior of the spike protein. More information would be needed to sort out if this mutation may be responsible for a host of possible problems down the line.

The Q493 Reversion

Reversions are likely to be a rare occurrence. Usually a mutation would confer some greater fitness onto the virus, and the idea that a dominant subvariant contains a reversion means that more is likely to be at play.

But in order to answer why a reversion may have occurred, we should see what fitness the Q493R mutation provided.

The Q493R mutation is a shift from a Glutamine (polar, uncharged side chain) to an Arginine (polar, positively charged side chain). From there, we may posit that a change to an Arginine with the positive charge may provide fitness to interact with negatively charged residues on the ACEII receptor. This amino acid is located within the RBM, so it is likely to play a critical role in binding to ACEII.

What’s interesting about this mutation is that the Q493R mutation is one of the sole reasons many of the antibodies in prior use generally saw loss of binding activity.

This mutation is responsible for the loss of functionality for Eli Lily’s dual therapy of Bamlanivimab and Etesevimab.
Although R is a charged residue, the evidence suggests that the longer side chain length may have led to steric hindrance (too crowded) which may have affected hydrogen bonding7:

The mutation Q493R can induce the disappearance of hydrogen bonds or the collision of antibody CDRH3 region by causing the change of amino acid spatial structure, which may explain the neutralization failure of Etesevimab (class 1/group A) and Bamlanivimab (class 2/group C).

In fact, there is plenty of evidence within the literature to suggest that monoclonal therapy in immunocompromised individuals may lead to selection for a Q493 mutation.

For example, the CDC cites8 the emergence of the Q493R mutation in a 73-year old cancer patient who was given an infusion of Bamlanivimab/Etesivimab. In another case9 an immunocompromised man treated for persistent COVID was provided several doses of Remdesivir and was eventually provided Regeneron on day 143 of his infection. Sequencing analysis indicated the emergence of a Q493K mutation, and was likely to have emerged through persistent infection.
Note that both of the mutations above were mutations towards a positively charged amino acid. This would indicate that this mutation likely favored interactions with negatively charged amino acid residues of the ACEII receptor.

Now, this does raise questions as to whether there may be some association between mAB use and the emergence of these mutations, but keep in mind that mABs are isolated from people who have been naturally infected by COVID, and therefore these antibodies are ones that our bodies are likely to produce ourselves. Essentially, this means that ALL of us- either naturally immune or vaccinated, may select for this mutation.

Interestingly, this reversion back to the Q493 residue carries with it an interesting conundrum. For those of us who were infected with the original Omicron, may we expect that we do not have proper antibodies to target epitopes that contain this amino acid? Would those who were originally infected with variants such as the Wuhan strain, Alpha, or even Delta be protected since they likely have antibodies against this epitope?

William Haseltine from the Forbes article suggests that prior monoclonals may work against Ba.4 and Ba.5, however the existence of other mutations may halt that possibility (Focosi, et. al.):

E484, F490, Q493, and S494 are the 4 aa residues within the spike protein receptor-binding motif that are known to be critical for bamlanivimab binding. Q493 is also among the many more receptor-binding motif residues crucial for interactions with etesivimab.

To provide additional context, Bamlanivimab first loss effectiveness during the emergence of Alpha, which caused Eli Lily to withdraw their EUA approval and return later on with the addition of Etesivimab. Interestingly, Bamlanivimab/Etesivimab suffer from the cardinal sin in monoclonal therapy- your antibodies should not share epitopes. Essentially, both Bamlanivimab and Etesivimab share similar epitopes on the RBD of the spike protein, and as soon as a mutation such as the Q493 emerged both lost effectiveness. Granted, Bamlanivimab lost effectiveness around Alpha, which raises question as to why Bamlanivimab was included along with Etesivimab in the first place.

What this would mean is that Etesivimab may show some promise against Ba.4/Ba.5 while Bamlanivimab may still be considered ineffective. This may also suggest that Regeneron may be considered effective in tackling Ba.4 and Ba.5. Further research would be needed in order to figure out which epitopes Regeneron targets, but this may be a time for many medical professionals to reconsider utilizing these monoclonal antibodies once again in the wake of Ba.4/Ba.5 due to this reversion in mutation.

For more on Monoclonal Antibodies in the wake of Omicron, I suggest my Monoclonal Anthology Series.

With all that being said, we need to make sense of the existence of this reversion.

It appears we can make a case that the Q493R mutation may have provided greater affinity to the ACEII receptor. One computer model10 suggests that a Q493K mutation adds additional hydrogen bonding capabilities. Therefore, something similar may arise with Arginine. In general, this would suggest that a reversion back to a Q493 residue should reduce some binding affinity of the spike protein.

So if this reversion is detrimental, why did it come about?

It’s likely that the L452R mutation is aiding the virus the most in its virulence. It could be that the overall net fitness would favor a variant that carried both the L452R mutation as well as the Q493 reversion. Having those two around may be better than not having the L452R mutation present in general.

However, there is a possibility that the 69-70 deletion may have worked here to provide some compensatory mechanism for the reversion. Essentially, the deletion may have come about in response to the Q493 reversion.

This is a bit of a speculation since the emergence of Q493R with Ba.1 came with this deletion. However, a combination of the other mutations may have led to a favoring of the 69-70 deletion, such as the L452R mutation, which actually fits more closely to the results from the Meng, et. al., and may be the primary reason for the 69-70 deletion along with Q493 reversion.

Overall, this reversion is one of the strangest aspects of Ba.4/Ba.5. It likely offers no greater fitness, and actually raises questions as to what this means for prior immunity, or even monoclonal antibody treatments that were revoked as soon as Omicron gained dominance.

The complexities of variants

Ba.4/Ba.5 present with an interesting scenario. Two of the mutations are ones we have seen before (69-70 deletion and L452R) while one is a reversion back to old strains (Q493).

However, in this context there are serving as add-ons (add-offs for Q493?) to Ba.1, which already presented with several dozen mutations of its own. Although we are left wondering how natural immunity or the vaccines will interact with Ba.4/Ba.5, it’s the combination of these mutations within Omicron that makes for a complex scenario.

And it’s the complex scenario that we must make sure to keep in mind. As of now, plenty of conspiracies are running about as to this subvariant, with a few suggesting that this is a variant of the vaccinated, even if most of these assumptions aren’t derived from the literature. It’s easy to look at case rates and make assumptions, but in order to examine the nuances and complexities to suggest that this is a variant of the vaccinated, we need to examine all of the factors required to make such an assumption.

Since this article has gone on too long, the next article will provide a review into immunity variables and whether we can extrapolate anything meaningful to make suppositions, or if a lot of the current assumptions are up in the air (for the time being).
.
 

Heliobas Disciple

TB Fanatic
(fair use applies)

J’ACCUSE! THE SPIKE ANTIBODY/FC-RECEPTOR COMPLEX IS SOURCE OF SEVERE COVID AND THE INDUCTION OF SYSTEMIC AUTOIMMUNE DISEASE: ONE SIDE OF THE AUTOIMMUNE/AMYLOIDOSIS SARS-CoV-2 COIN - AND IT WAS KNOWN!
Paper Published Feb 2020 by Shi Zhengli (clearly written before pandemic appeared) as Smoking Gun
Walter M Chesnut
5 hr ago

I believe I have discovered the mechanism by which the Spike Protein is causing severe disease and autoimmune disease. In both cases, the mechanism is the same. Autoimmunity and Amyloidosis are the two sides of the SARS-CoV-2 coin. And they are present in both the acute phase and the so-called Long COVID (or PASC) phase (rapid and indolent, respectively).

THE HISTORY

In June 2018, a paper was published in the Hong Kong Medical Journal called Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS. The paper has a very interesting Discussion:

The findings of this study partially invalidated our initial hypothesis that antibody-mediation would, by widening tropism of SARS-CoV toward immune cells, elicit an altered profile of immune mediators that impair homeostasis of the immune system and ultimately contribute to SARS pathogenesis.

BUT! In the very next sentence, the authors go on to say:

Nonetheless, it is still intriguing to us that triggering an enhanced infection of cornerstone innate immune cells such as macrophages would have no consequences. It is true that in contrast to studies that showed cell perturbation following ADE-infection, others have documented fewer, barely discernible consequences. Hence it is possible that ADE of SARS-CoV infection is happening without deleterious consequences to the target cells.

The paper then concludes:

Our results suggest the rational development of vaccination strategies in the event of a SARS-like virus outbreak, with reasonable concerns about the occurrence of severe adverse effects.

MOVE AHEAD TO FEBRUARY 2020, MERE WEEKS BEFORE THE PANDEMIC WAS DECLARED

A PAPER PUBLISHED BY NONE OTHER THAN SHI ZHENGLI MADE THE FOLLOWING DISCOVERY:



The authors found that MERS-CoV and SARS-CoV DO have Fc receptor mediated and DOSAGE DEPENDENT mediated Antibody Dependent Enhancement (ADE)! This may, at long last, explain why there seems to be more severe disease at points post vaccination and why, if the virus is not cleared, the DOSAGE of antibodies within the body from infection can then cause progression of the disease! (Please note the mention of the placenta, as well, in the following quote.)

Finally, we analyzed ADE of coronavirus entry at different antibody dosages. MERS-CoV entry into cells expressing both viral and Fc receptors demonstrates complex MAb-dosage-dependent patterns. As the concentration of MAb increases, (i) viral entry into DPP4-expressing cells is inhibited more efficiently because MAb binds to the spike and blocks the DPP4-dependent entry pathway, (ii) viral entry into Fc receptor-expressing cells is first enhanced and then inhibited because MAb binds to the Fc receptor to enhance the ADE pathway until the Fc receptor molecules are saturated, and (iii) viral entry into cells expressing both DPP4 and Fc receptor is first inhibited, then enhanced, and finally inhibited again because of the cumulative effects of the previous two patterns. In other words, for viral entry into cells expressing both DPP4 and Fc receptor, there exists a balance between the DPP4-dependent and antibody-dependent entry pathways that can be shifted and determined by MAb dosages. Importantly, ADE occurs only at intermediate MAb dosages. Our study explains an earlier observation that ADE of dengue viruses occurs only at certain concentrations of MAb. While many human tissues express either DPP4 or Fc receptor, a few of them, most notably placenta, express both of them. For other viruses that use viral receptors different from DPP4, there may also be human tissues where the viral receptor and Fc receptor are both expressed. The expression levels of these two receptors in specific tissue cells likely are determinants of MAb dosages at which ADE would occur in these tissues. Other determinants of ADE-enabling MAb dosages may include the binding affinities of the MAb for the viral and Fc receptors. Overall, our study suggests that ADE of viruses depends on antibody dosages, tissue-specific expressions of viral and Fc receptors, and some intrinsic features of the antibody.



THE SPIKE PROTEIN ANTIBODY/Fc RECEPTOR COMPLEX AND SYSTEMIC AUTOIMMUNITY

This then brings us to those who survive the acute infection. Given the previously mentioned paper, everything may be related to LEVELS of antibodies. Could it be that those who “lose” antibodies more quickly post-infection, ironically, fare better in the long run?

On March 24 of this year, a paper was published in Communications Biology entitled Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interaction.

In this paper they reveal a novel ADE mechanism of SARS-CoV-2 pseudovirus in vitro, FcγRIIB-mediated uptake of SARS-CoV-2/mAb complex with bivalent interaction.

What does this mean?

I believe this is keystone of the systemic autoimmunity we are observing. Based on recent studies of autoimmune diseases in mice, it is activating FcRs which has been shown to promote disease development, whereas the inhibitory FcR FcγRIIB maintains peripheral tolerance. However! This is the VERY RECEPTOR which the COMPLEX INTERACTS WITH!



After all, is not the panoply of Kawasaki disease (MIS-C, MIS-A), dermatomyositis and antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis, systemic lupus erythematosus, polymyositis and catastrophic antiphospholipid syndrome among others what we are observing?

AND! PERHAPS THE MOST FASCINATING POINT! IS IT THE LEVELS OF ANTIBODIES PRESENT WHICH DETERMINE WHO DEVELOPS MIS-C, FOR EXAMPLE? DOES THIS SOLVE THE LONGSTANDING MYSTERY?

I believe it may.

The therapeutic question in all of this is: Could Therapeutic Intravenous Immunoglobulin be an effective therapeutic?

Intravenous immunoglobulin therapy in rheumatic diseases
Intravenous immunoglobulin therapy in rheumatic diseases - Document - Gale Academic OneFile

Roles of Fc receptors in autoimmunity
Roles of Fc receptors in autoimmunity - Nature Reviews Immunology

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry
Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interaction
Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interaction - Communications Biology

Antibody-dependent enhancement of SARS coronavirus infection
https://www.hkmj.org/system/files/hkm1603sp4p25.pdf
 

Heliobas Disciple

TB Fanatic
(fair use applies)

Australia, et tu on vanishing COVID vaccine mandates? Et Tu? Rabid punishing you, Mr. Australia? jailing people who refused, who had natural immunity? you now slinker away you freak coward govn!!!
This week, & hardly a whisper from its chief public health officers, Australia largely abandoned its vaccine mandates. There has been no explanation given as to why unvaccinated workers can now return
Dr. Paul Alexander
17 hr ago

“This week, with hardly a whisper from its chief public health officers, Australia largely abandoned its vaccine mandates. For the most part, they remain in force only for those working in health and aged care or with those with disabilities. There has been no explanation given as to why unvaccinated workers can now be ‘welcomed back’ into workplaces. There has been no apology to those who lost their jobs for refusing to be jabbed, or who lost their lives, or their good health, following vaccination.”

“So far, 889 deaths have been reported to the Therapeutic Goods Administration (TGA) which may have been caused by vaccination and almost 133,000 people have reported a vaccine injury including more than 140 heart attacks, 360 myocardial infarctions, 500 strokes, 1,400 cases of deep vein thrombosis and 1,500 pulmonary embolisms.”

“Increased vulnerability to infection might explain why, in NSW, teachers who were forced to be double vaccinated to retain their jobs were off sick for a combined 430,351 days in the first six months of this year, an increase of 145,491 days compared to pre-pandemic levels.”

“It might also explain why excess mortality continues to run at a record high. Excess deaths in March were still almost 10 per cent above the historical baseline and deaths for the first three months of the year were 17.5 per cent higher than the historical average.

This spectacular public health failure was undoubtedly exacerbated by the failure to heed the lessons of early treatment of Covid-19. This time last year, on 26 June, NSW entered its long Delta lockdown. At that time, India was just emerging from its Delta spike. On 26 June 2021, Covid deaths in India were 284 per million, while in Australia they were only 35 per million. A year later on 26 June, deaths per million in Australia and India are identical – 376 per million. What happened?

A year ago, health officials in Uttar Pradesh, the most populous state in India, with 240 million inhabitants, advised that they were using a multi-drug cocktail of repurposed medications including ivermectin and hydroxychloroquine to treat Covid with astonishing success. From a peak of 34,455 on 29 April, cases plunged to 178 on 26 June. A year later there is an average of one death per day.

The contrast with Australia could not be more stark. Australia’s public health officers weren’t content simply to disregard the evidence of Uttar Pradesh’s success with a multi-drug therapy that included ivermectin, the TGA went further than any other country in the world and on 10 September 2021 banned the use of ivermectin for the treatment of Covid.”

SOURCE:

Vanishing vaccine mandates; No apology from our once-so-zealous public health officials
 

Heliobas Disciple

TB Fanatic
(fair use applies)

Immuno-epidemiologic ramifications of the C-19 mass vaccination experiment: Individual and global health consequences.
Geert Vanden Bossche, DVM, PhD
General Manager at Voice for Science and Solidarity | The biggest challenge in vaccinology: Countering immune evasion
Jul. 4, 2022, 9:30 a.m.

Opinion Article

The mass vaccination program has driven natural selection and adaptation of more infectious SARS-CoV-2 (SC-2) variants that have now evolved to causing enhanced susceptibility of vaccinees to infection (due to antibody-dependent enhancement of infection; ADEI). The resulting recurrence of infectious episodes leads to hyperactivation of cytotoxic CD8+ T cells that are directed at a universal (i.e., MHC-unrestricted) T cell epitope comprised within the SC-2 spike (S) protein. As these cytotoxic CD8+ T cells enable prompt abrogation of productive infection and as this epitope is shared amongst some other glycosylated viruses causing acute self-limiting infection or disease, more and more cases of asymptomatic infections are to be expected in vaccinees, especially in those endowed with a mature and fully functional innate immune system. These asymptomatic infections are not limited to more infectious and antigenically shifted SC-2 variants but also include other infections that use the same cytotoxic T cells (CTLs) to abrogate productive infection (e.g., influenza virus, poxvirus, respiratory syncytial virus [RSV]). However, as prevention of disease in vaccines is, therefore, no longer based on prevention of infection by neutralizing antibodies, asymptomatic vaccinees abundantly spread highly infectious SC-2 immune escape variants as well as other highly infectious, immunogenically related viruses to other parts of the population. Consequently, in a highly vaccinated, well-mixed population, vaccinees with a mature and healthy innate immune system are now to be considered an asymptomatic reservoir for transmission of new, highly infectious SC-2 immune escape variants and other highly infectious diseases to the remainder of the population. The resulting enhanced viral transmission rate is likely to ignite new pandemics (see fig. 1), not only of new, highly infectious, and antigenically shifted SC-2 variants (typically labeled as ‘variants of concern’) but also of avian influenza virus and monkeypox virus. Elderly vaccinees could serve as an asymptomatic reservoir for less infectious immunogenetically related viruses such as RSV or common influenza strains. Transmission of RSV or influenza virus from asymptomatic vaccinated elderly to young children could disconnect the occurrence of these diseases from seasonality and hence, lead to a ‘childhood’ pandemic of RSV and influenza (currently already causing hospitalizations of children). Pseudo herd immunity (i.e., generated by continuous activation of cross-reactive cytotoxic CD8+ T cells) is currently mitigating the severity of the three major pandemics (i.e., P1, P2, P3: see chart attached below) in that it largely prevents cases of severe infectious disease in the bulk of highly vaccinated populations with cases of severe disease now only occurring in a limited number of young children. However, this situation is anything but stable and will only last for as long as the dominant Omicron (sub)variants are not fully resistant to the vaccine-induced infection-enhancing antibodies (Abs). In the meantime, though, continuous boosting of highly vaccinated populations by the circulating Omicron (sub)variants is highly likely to soon enable the virus to break through this adaptive immune defense. When this happens, no single immune defense mechanism will be left to fight off the virus, which will take advantage of the infection-enhancing effect of the vaccinal Abs to cause ADEI-facilitated enhanced disease (so-called Ab-dependent enhancement of disease; ADED) in vaccinees. Without early antiviral treatment, this C-19 super pandemic (referred to as P4 in the chart appended below) will likely result in a fulminant increase in the mortality rate in the vaccinated population before any of the other pandemics can cause the same type of damage. The first signal of this catastrophic evolution will be reflected by a rapid shift and steep increase of the C-19 hospitalization rate of vaccinees to unvaccinated from below 1 (<1) to above 1 (>1) in the age group between 10 and 60y (see fig. 2 below). Vaccination of young children will only simulate the effect of infection-enhancing Abs blowing through the innate immune system, even before new circulating immune escape variants enable ADED in the remainder of the vaccinated population.

At the same time, hyperactivation of poorly MHC-restricted cytotoxic CD8+ T cells leads to depletion of CTLs that normally collaborate with innate immune effector cells to keep other glycosylated, immunogenically unrelated pathogenic agents in check, such as glycan-associated cancer antigens or glycosylated pathogens causing chronic self-controlling microbial infections (e.g., EBV, CMV, herpetic infections, HIV, tuberculosis…). Depletion of CTLs may, therefore, promote cancer metastasis or cause microbial disease due to recurrence/ reactivation of such latent/ dormant infections in vaccinees.

Depending on the immune status of both the cell-based innate immune system (CBIIS; i.e., untrained as opposed to well-trained or moderately trained) and the Ab-based adaptive immune system (i.e., no S-specific Abs in the unvaccinated as opposed to S-specific infection-enhancing Abs in the vaccinated) in other subsets of the population at this stage of the C-19 pandemic, exposure may lead to mitigated or more severe symptoms of disease (see chart below).

In addition, SC-2 variants[1] may also spill over from these human reservoirs to several other immunologically naïve (i.e., in terms of adaptive immunity) animal species, many of which have a reasonably high level of sequence homology in their ACE-2 receptor. This particularly applies to animal subpopulations that develop antigen-specific Abs upon exposure as a result of a weakened CBIIS. Re-exposure of such animal population to antigenically shifted viral variants that originate from the human reservoir is likely to cause severe disease and death in these animal subpopulations (due to enhanced susceptibility to disease as a result of ADEI). The resulting increase in viral infectious pressure could subsequently ignite similar pandemics in one or more animal populations, including livestock.

On the other hand, the monkeypox and avian influenza pandemic will particularly hit human populations that combine relatively low vaccination rates with low levels of trained innate immunity (e.g., due to stringent infection-prevention measures combined with a tolerant vaccine policy, as is, for example, the case in China). Countries that combine low vaccine coverage rates and with well-trained innate immunity and are relatively young will suffer much less from any of these pandemics and only for as long (short?!) as asymptomatic reservoirs in highly vaccinated countries exist. Africa will win!

Annex: Figures and chart

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Fig. 1: as presented by Dr. G. Vanden Bossche at 2nd C-19 World Congress of Doctors for Life and WCH. June 30- July 3, 2022; Foz do Iguaçu, Brasil

The chart below summarizes the type of disease the above-mentioned pandemics are expected to cause in a well-mixed, highly vaccinated population and how the incidence rate of severe disease (and hence, the hospitalization rate) is expected to evolve in the vaccinated as compared to the unvaccinated part of the population, depending on the maturity/strength and training of the CBIIS. Enhanced viral transmission from the asymptomatically infected group of C-19 vaccinees to other parts of the population will cause 2 new types of pandemics[2], i.e., a pandemic of acute, self-limiting or chronic, self-controllable microbial infections (P2) and a pandemic of acute, self-limiting microbial diseases (P4) on top of the further expansion of the ongoing pandemic of ‘more infectious’ SC-2 variants (P1) that will finally transform in a much more severe pandemic which will only affect highly vaccinated countries (P4). The health impact of the commencing pandemics (i.e., P2 and P3) and those currently ongoing or lying ahead (i.e., P3 and P4, respectively) in a highly vaccinated population will be described in more detail in the full manuscript (to be published soon).

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Abbreviations:
Abs: Antibodies
ADED: Antibody-dependent enhancement of disease
ADEI: Antibody-dependent enhancement of infection
AF: Avian Flu (influenza)
ASLMI: Acute self-limiting microbial infection
C-19 vaccinated/ vaccinee or C-19 unvaccinated: relates to individuals/ populations that have been vaccinated or not been vaccinated with Covid-19 vaccines, respectively
ASLVD: Acute self-limiting viral disease
CBIIS: Cell-based innate immune system
CSCMI: Chronic self-controllable microbial infection (i.e., self-controllable by the host immune system)
IE2: 2nd immune escape event (triggering resistance to virulence-neutralizing activity of infection-enhancing Abs
MP: Monkeypox
P1: new C-19 pandemic that has been initiated as a result of the mass C-19 vaccination program and is continuously fueled by natural selection and adaptation of ‘more infectious,’ antigenically shifted SC-2 variants (variants of concern). This is the family of more infectious C-19 pandemics (i.e., caused by ‘more infectious’ SC-2 variants).
P2: new and already ongoing pandemic of ASLMIs and CSCMIs
P3: new and already ongoing pandemic of ASLVDs (AI + MP)
P4: upcoming C-19 super-pandemic of new viral variants that trigger ADEI-mediated disease (i.e., ADED) in vaccinees. This is the C-19 pandemic of ‘highly virulent’ variants.
sFlu: seasonal Influenza; refers to common Influenza virus types

Notes related to the chart above:

- The age groups don’t exactly correspond to the status of the CBIIS described and only provide a ballpark figure on the age range of groups comprising the majority of people with the indicated CBIIS status

- For the purpose of this contribution, the term ‘vulnerable’ refers to the CBIIS status of people/ individuals with co-morbidities/ underlying diseases are who are otherwise immunosuppressed or immunodeficient

- For the purpose of this contribution, the term ‘elderly’ refers to people/ individuals with an immunosenescent CBIIS (i.e., alteration of its immune functions due to aging).

- For the purpose of this contribution, the term ‘young children’ refers to people/ individuals with an immature CBIIS

- ‘Severe’ disease is highlighted in bold when the incidence is predicted to increase; this should provide guidance on the upcoming need for larger hospitalization capacity

- Smaller text fonts are used for indicating diseases predicted to occur upon exposure of young children as the majority of them are not yet vaccinated

- Purple text fonts indicate the asymptomatic reservoir responsible for igniting the P1 pandemic and the types of disease caused by viral transmission to different groups of the population. Because ‘more infectious’ variants raise the infection rate in the population, they compromise innate immunity in young unvaccinated children, whereas they improve innate immune training in the remainder of the unvaccinated population. As ‘more infectious’ variants become more and more resistant to potentially neutralizing vaccinal Abs, they bind more readily to infection-enhancing Abs. The latter are capable of blocking trans infection and trans fusion in vaccinees and thereby enhance abrogation of productive infection (via cytotoxic CD8+ T cells), which results in reduced virulence and diminished viral shedding, respectively.

- Red text fonts indicate the asymptomatic reservoir responsible for igniting the P2 pandemic and the types of disease caused by viral transmission to the different groups of the population

- Black text fonts indicate the asymptomatic reservoir responsible for igniting the P3 pandemic and the types of disease caused by viral transmission to the different groups of the population

- Green text fonts indicate the asymptomatic reservoir responsible for igniting the P4 pandemic and the types of disease caused by viral transmission to the different groups of the population. As currently circulating Omicron (sub)variants become more and more resistant to potentially virulence-neutralizing vaccinal Abs (i.e., capable of enhancing trans infection and trans fusion in this part of the population) via glycan-mediated shielding, infection by these variants will rapidly become highly virulent in vaccinees, but not in the unvaccinated.

Fig. 2 below illustrates the predicted trend of the relative[3] change in the rates of severe C-19 disease (requiring hospitalization) within the C-19 vaccinated versus C-19 unvaccinated people based upon the same criteria used in the table attached (highly vaccinated population). Only columns colored in yellow represent hospitalization rates due to Covid-19. Framed columns represent the part of the population with a poorly functional CBIIS (mostly young children, elderly, and other vulnerable people) in the unvaccinated or vaccinated part of the population (1, 2, 3 or 1’, 2’, 3’, respectively) whereas frameless columns represent unvaccinated or vaccinated people with a mature and trained CBIIS (A, B, C or A’, B’, C’, respectively). Up and down arrows indicate whether the change in hospitalization rate is expected to increase or decrease, respectively, whereas the arrow length indicates the expected magnitude of change. The chart does not include vaccinated young children as - even in highly vaccinated populations - the vast majority of young children has not yet been vaccinated.

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As SC-2 will evolve to become more and more resistant to the ‘trans infection’-blocking capacity of the infection-enhancing Abs, the case fatality rate in the vaccinated population will rapidly and dramatically increase, first in the vaccinated elderly (+ the vulnerable) and soon thereafter also in the rest of the vaccinated population (cfr. 3’ followed by D’). However, as the virus increases the pace of evolution across the fitness valleys required to escape to the population-level immune pressure exerted on its virulence, the ADED-enabling immune escape will first become apparent in the group aged between > 5(10) y and < 60 (65) y (cfr. C’). This is because their CBIIS can clear a substantial part of the viral load and can, therefore, reduce the amount of free-circulating virus to a concentration that is low enough to become more sensitive to a relatively small change in the virulence-neutralizing capacity of non-neutralizing S-specific Abs. Consequently, it is reasonable to assume that waning of the virulence-neutralizing capacity of these Abs will first become manifest (and hence, cause an increased incidence of severe C-19 disease) in the part of the vaccinated population that has the stronger innate immune capacity. However, once the affinity of the virulence-neutralizing Abs (which still serve as ‘infection-enhancing’ Abs at the upper respiratory tract!) has reached a level that is low enough to no longer bind to the infection-enhancing site on the N-terminal domain (NTD) of spike protein expressed on ‘trans infection-competent’ virions (i.e., not free-circulating but tethered to the surface of migratory dendritic cells[4]), these Abs will start to massively bind to the infection-enhancing site of S-NTD as expressed on the free-circulating virion. In immunosenescent or vulnerable people, this will undoubtedly lead to a sudden and spectacular shift from protection against severe disease to enhanced susceptibility to severe disease (ADED), but it will very soon also leave the mature CBIIS of the bulk of the vaccinated population without any compensation mechanism to buffer the enhanced infectiousness of the virus. This leads to the following sequence of ADED manifestations: C’ rapidly followed by 3’ and D’.

As the second viral immune escape event (enabling ADED) does not affect the unvaccinated, the proportion between vaccinated and unvaccinated people needing hospitalization because of severe C-19 disease is expected to rise rapidly in the age group between 10 and 60 years (i.e., [C’:C] > [B’:B). This will be the most sensitive, and hence, first measurable signal of the evolution of SC-2 toward an infectious behavior that will be responsible for initiating a massive ADED-mediated incidence of severe disease and hospitalization in the overall vaccinated part of the population.

Once the immune escape variant spreads to the remainder of the vaccinated population that is even more susceptible to severe disease (although it exerted much less immune pressure on the life cycle of the virus!) because of its poorly functional innate immune system, the ratio of C-19-related hospitalizations in the vaccinated as compared to the unvaccinated group will increase even more spectacularly when calculated on the basis of the overall population, i.e., ([3’ + C’] : [3 + C]) > ([2’ + B’] : [2 + B]) and ([3’ + C’] : [3 + C]) >> [C’:C].


[continued in next post]
 

Heliobas Disciple

TB Fanatic
[continued from post above]

[1] Viruses that are largely controlled by non-specific innate immunity also have relatively low receptor specificity

[2] ‘Pandemics’ and not ‘epidemics’ as the spread and transmission of these infectious pathogens will not be restricted to highly vaccinated countries

[3] As it is the purpose to illustrate changes within each group, column height should not be compared between the vaccinated and unvaccinated group

[4] https://www.voiceforscienceandsolidarity.org/scientific-blog/predictions-gvb-on-evolution-c-19-pandemic

The mass vaccination program has driven natural selection and adaptation of more infectious SARS-CoV-2 (SC-2) variants that have now evolved to causing enhanced susceptibility of vaccinees to infection (due to antibody-dependent enhancement of infection; ADEI). The resulting recurrence of infectious episodes leads to hyperactivation of cytotoxic CD8+ T cells that are directed at a universal (i.e., MHC-unrestricted) T cell epitope comprised within the SC-2 spike (S) protein. As these cytotoxic CD8+ T cells enable prompt abrogation of productive infection and as this epitope is shared amongst some other glycosylated viruses causing acute self-limiting infection or disease, more and more cases of asymptomatic infections are to be expected in vaccinees, especially in those endowed with a mature and fully functional innate immune system. These asymptomatic infections are not limited to more infectious and antigenically shifted SC-2 variants but also include other infections that use the same cytotoxic T cells (CTLs) to abrogate productive infection (e.g., influenza virus, poxvirus, respiratory syncytial virus [RSV]). However, as prevention of disease in vaccines is, therefore, no longer based on prevention of infection by neutralizing antibodies, asymptomatic vaccinees abundantly spread highly infectious SC-2 immune escape variants as well as other highly infectious, immunogenically related viruses to other parts of the population. Consequently, in a highly vaccinated, well-mixed population, vaccinees with a mature and healthy innate immune system are now to be considered an asymptomatic reservoir for transmission of new, highly infectious SC-2 immune escape variants and other highly infectious diseases to the remainder of the population. The resulting enhanced viral transmission rate is likely to ignite new pandemics (see fig. 1), not only of new, highly infectious, and antigenically shifted SC-2 variants (typically labeled as ‘variants of concern’) but also of avian influenza virus and monkeypox virus. Elderly vaccinees could serve as an asymptomatic reservoir for less infectious immunogenetically related viruses such as RSV or common influenza strains. Transmission of RSV or influenza virus from asymptomatic vaccinated elderly to young children could disconnect the occurrence of these diseases from seasonality and hence, lead to a ‘childhood’ pandemic of RSV and influenza (currently already causing hospitalizations of children). Pseudo herd immunity (i.e., generated by continuous activation of cross-reactive cytotoxic CD8+ T cells) is currently mitigating the severity of the three major pandemics (i.e., P1, P2, P3: see chart attached below) in that it largely prevents cases of severe infectious disease in the bulk of highly vaccinated populations with cases of severe disease now only occurring in a limited number of young children. However, this situation is anything but stable and will only last for as long as the dominant Omicron (sub)variants are not fully resistant to the vaccine-induced infection-enhancing antibodies (Abs). In the meantime, though, continuous boosting of highly vaccinated populations by the circulating Omicron (sub)variants is highly likely to soon enable the virus to break through this adaptive immune defense. When this happens, no single immune defense mechanism will be left to fight off the virus, which will take advantage of the infection-enhancing effect of the vaccinal Abs to cause ADEI-facilitated enhanced disease (so-called Ab-dependent enhancement of disease; ADED) in vaccinees. Without early antiviral treatment, this C-19 super pandemic (referred to as P4 in the chart appended below) will likely result in a fulminant increase in the mortality rate in the vaccinated population before any of the other pandemics can cause the same type of damage. The first signal of this catastrophic evolution will be reflected by a rapid shift and steep increase of the C-19 hospitalization rate of vaccinees to unvaccinated from below 1 (<1) to above 1 (>1) in the age group between 10 and 60y (see fig. 2 below). Vaccination of young children will only simulate the effect of infection-enhancing Abs blowing through the innate immune system, even before new circulating immune escape variants enable ADED in the remainder of the vaccinated population.

At the same time, hyperactivation of poorly MHC-restricted cytotoxic CD8+ T cells leads to depletion of CTLs that normally collaborate with innate immune effector cells to keep other glycosylated, immunogenically unrelated pathogenic agents in check, such as glycan-associated cancer antigens or glycosylated pathogens causing chronic self-controlling microbial infections (e.g., EBV, CMV, herpetic infections, HIV, tuberculosis…). Depletion of CTLs may, therefore, promote cancer metastasis or cause microbial disease due to recurrence/ reactivation of such latent/ dormant infections in vaccinees.
 

Heliobas Disciple

TB Fanatic
Interview between Dr. Paul Alexander and Geert Vanden Bossche.

The video cuts off at the end, they apparently run of out time.


Dr. Geert Vanden Bossche: These vaccines are extremely dangerous for children
PAlexanderPhD
Published July 6, 2022
38 minutes 09 seconds

Dr. Paul Elias Alexander discusses the COVID vaccine with Dr. Geert Vanden Bossche. July 6, 2022
My content is available for free. I have lost extensive income due to my advocacy for early treatment and my stance against the COVID vaccines, especially for children. Your kindness and generosity is very much appreciated in my sharing of research and the fight against scientific censorship where several good and brilliant doctors and scientists are silenced and cancelled, including myself. It is absolutely imperative that people/populations are given accurate information about the benefits and harms of societal restrictions or medical interventions such as vaccines. Only then can people make informed decisions about what is best for them.
 

Heliobas Disciple

TB Fanatic
ETA: Apologies - this is a dupe. I see Zoner posted this a few pages up. worth the watch again though so no harm done....


Video done by Geert Vanden Bossche (by himself) to warn parents against vaccinating their children.


Don't vaccinate your children with covid-vaccines! Ever!
Voice for Science and Solidarity
Published July 3, 2022
16 min 42 sec

Dr. Vanden Bossche goes over his theory why vaccinating children is dangerous for their immune systems and advises parents against vaccinating their children.
 
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Zoner

Veteran Member

The immuno-epidemiological consequences of the mass vaccination experiment - summary

Geert Vanden Bossche




Dear all,
For the past two weeks I have been working on a document summarizing my conclusions on the immuno-epidemiological consequences of the mass vaccination experiment.

The result of this is even more frightening than I had predicted. I’ve, therefore, appended a summary of my manuscript by way of ‘tsunami warning’.

In a nutshell, here is what I am 100% certain of:

The current SC-2 pandemic is still expanding as it is a pandemic of ‘more infectious’ variants and is thus enhancing the susceptibility of vaccinees to infection (infection-enhancing antibodies) while diminishing the susceptibility of the unvaccinated (infection-mediated training of innate cell-mediated immunity).
  • In the pre-Omicron era, we saw more infectious variants becoming dominant; however, thanks to the neutralizing antibodies, vaccinees were still protected against disease. However, with the advent of Omicron and its growing resistance to neutralizing antibodies, vaccinees became more susceptible to infection; what we are now seeing is more virulent variants becoming dominant (Omicron subvariants BA.4 and BA.5[1]). however, thanks to the virulence-neutralizing antibodies (which are the same as those enhancing infection at the upper respiratory tract!), vaccinees were still protected against severe disease (e.g., in case of BA.1 and BA.2). I’ve no doubt, however, that with the growing resistance of BA.4 and BA.5 to the virulence-neutralizing Abs, vaccinees will now rapidly become more susceptible to virulence.
  • Due to repetitive activation of the immune system in C-19 vaccinees, several infectious diseases can now be spread asymptomatically by vaccinees. Due to widespread asymptomatic transmission in highly vaccinated countries and the subsequent rise in infectious pressure, infection-mediated immunity in certain subsets of the population no longer suffices to prevent productive infection. This is now basically igniting the global spread of a number of acute, self-limiting microbial infections (e.g., ‘seasonal’ Flu, RSV but also vaccine-preventable viral and bacterial infections in countries that interrupted their childhood vax program due to Covid crisis) and also of some acute, self-limiting viral diseases (e.g., monkeypox, pandemic [avian H5N1] flu). In addition, depletion of cytotoxic CD8 T cells due to repetitive cycles of re-infection has also led to an increased recurrence/reactivation rate of chronic infections (e.g., herpetic diseases + CMV, EBV, CMV, HIV, tuberculosis..) and relapse or metastasis of certain cancers in vaccinees.
  • In the summary appended, I am sharing my informed predictions on the health impact these pandemics will entail in different subgroups of a highly vaccinated population. While these new pandemics are developing, the super C-19 pandemic I’ve been warning about is coming our way soon. In highly vaccinated countries, it will definitely overhaul the pandemics mentioned above. This is because massive replacement of ‘natural infection-acquired’ immunity to SC-2 by ‘imperfect’ vaccine-induced immunity is now driving the evolution of the C-19 pandemic in highly vaccinated countries. This will not be the case in poorly vaccinated countries where natural immunity has been largely preserved and the population is often much younger (e.g., African countries).
Last, I’d like to repeat my advice: If you’re C-19 vaccinated: Make sure you’ve access to antivirals and antibiotics and that you’ve established a contact with an MD you can trust.
  • If you’re not C-19 vaccinated: You should under no condition get the seasonal Flu shot as vaccination with inactivated Flu vaccines will dramatically increase the risk of catching ADEI in the event you get exposed to avian flu. Under no condition should you get a non-replicating smallpox vaccine. Since surface proteins of smallpox (using cowpox as live attenuated immunogen) are different from those decorating monkeypox, and as the non-replicating vaccine primarily induces antibodies (Abs), you could expose yourself to a real risk of ADEI. However, C-19 unvaccinated people don’t need a smallpox jab at all (and they don’t need an avian Flu vaccine either – in case the industry comes up with a pandemic flu vaccine!) regardless of whether they got the smallpox vaccine in the past. Training of our innate immune system against Coronavirus (i.e., SC-2) during the C-19 pandemic will not only provide strong innate immune protection against influenza virus and poxviruses but also against other glycosylated viruses causing acute, self-limiting infection (e.g., RSV, other common cold CoV). I can explain this, but that would take somewhat longer.
    [*]Upon exposure to smallpox or avian Flu, a C-19 unvaccinated person who is in good health and experienced mild or moderate C-19 symptoms as a result of previous natural infection (‘thanks’ to the C-19 pandemic) may still get some mild illness but that’s it! This will just induce additional antibodies to fully protect you next time around, pretty much like a live attenuated viral vaccine does. There is even a high likelihood that there won’t be a ‘vaccine take’ when you become vaccinated with live attenuated smallpox as your trained NK cells may kick out the vaccinal virus right away. However innate immune training against CoV (e.g., SC-2) will not protect against measles, mumps, rubella or varicella (M, M, R, V). So, I simply continue recommending you to vaccinate your child against these childhood diseases before local outbreaks/ epidemics occur. It’s never a good idea, and could be dangerous for the child, to get the MMRV shot during a situation of high infectious pressure. Also, it is not recommended to vaccinate older children / adults/ elderly with these live attenuated vaccines if they’ve not been vaccinated against those diseases before. So, those who didn’t receive these childhood vaccines and did not acquire natural immunity as a result of previous natural infection are at risk of contracting the disease in case of an outbreak.
    [*]Unvaccinated elderly and vulnerable people (e.g., with co-morbidities) have a risk of contracting moderate to severe disease from Flu or RSV. The likelihood for developing severe disease increases when the innate immune system is weakened, especially in case of exposure to high infectious pressure (the latter could, for example, rapidly build up in areas of high population density such as nursing homes. I would, therefore, recommend removing your parent/ grand-parents from nursing homes ASAP.
    [*]Live attenuated smallpox vaccine will not work in C-19 vaccinees because host cells that are infected with vaccinal virus will be readily recognized and killed by cytotoxic CD8 T cells that are continuously activated due to the enhanced susceptibility of vaccinees to re-infection.
    [*]C-19 vaccination of children must stop immediately. Not only will the C-19 vaccines fully prevent innate antibodies from neutralizing the virus, but they will also irreversibly prevent the innate antibodies (in association with the virus) from educating the cell-based innate immune system (e.g., NK cells). Instead, the vaccinal antibodies will enhance viral infectiousness and enable the virus to blow straight through the innate immune defense, thereby causing severe C-19 disease. It will also prevent the child from educating its innate immune system (a corner stone of natural immunity!) to recognize several other (glycosylated) pathogens while discriminating those from self-antigens. This could lead to severe disease caused by several other (glycosylated) pathogens which the child has not been vaccinated against as well as to severe immune pathology! It will also no longer be possible to vaccinate children with other live attenuated childhood vaccines once they’ve gotten the Covid-19 shot for these vaccines could now cause severe disease. So, the C-19 vaccine could be a death sentence for a young child!

You’ll find more details on these recommendations highlighted in the full manuscript I am still working on.
As far as the evolution of the C-19 pandemic is concerned, this is what you need to track if you want to know when the super C-19 pandemic is about to kick off:

When the ratio of the vaccinated to unvaccinated people in the age group 10-60 years old, who are hospitalized because of Covid-19, starts to rapidly increase, we will know that the super C-19 pandemic has begun. That’s the most sensitive criterion!

My heart goes out to the vaccinated people. The only way to bypass the malicious C-19 priming is to properly educate the vaccinee’s innate immune effector cells in the absence of replicating virus. It will be critical to treat them as of the early onset of symptoms. Treatment with antivirals shortly after infection could possibly train their innate immune system without boosting their infection-enhancing antibodies[2].

[1] https://www.biorxiv.org/content/10.1101/2022.05.26.493539v1.full.pdf

[2] Q&A #17 : What advice could one offer to vaccinees in the event that an immune escape Sars-CoV-2 variant adapts to the highly vaccinated population such as to enable high infectiousness combined with high virulence? | Voice for Science and Solidarity

http://applewebdata//F1DDAE4E-7B7C-42B6-A5FA-7F0E7CC316A0#_ednref1 For more info on approved replicating and non-replicating smallpox vaccines: MVA-BN smallpox vaccine | Bavarian Nordic;Vaccines | Smallpox | CDC
The original article can be found on TSN TrialSite News https://www.trialsitenews.com/a/immuno-epidemiologic-ramifications-of-the-c-19-mass-vaccination-experiment-individual-and-global-health-consequences.-1935ddcf


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Mass infection prevention and mass vaccination with leaky Covid-19 vaccines in the midst of the pandemic can only breed highly infectious variants.
 

Zoner

Veteran Member
Good Lord Dr GVB!
He’s terrifying to read.
But I trust what he says. He’s not been wrong, once.
Yes, it is terrifying. Even the doctors who interview him realize his expertise and others like Dr. Malone the discoverer of the mRNA messaging system and Dr. Weinstein, Dr. Jonathan Weissman, Dr. Paul Alexander and Dr. McCollough acknowledge his expertise.
God is present for those needing the peace only Jesus can provide. "Peace I leave with you, My peace I give to you; not as the world gives do I give to you. Let not your heart be troubled, neither let it be afraid."
The world as I see it is in the beginning of great troubles and tribulation.
"The Lord is my Refuge and strength, a very present Help in trouble." -Psalm 46
 

Zoner

Veteran Member
GVB "I’ve no doubt, however, that with the growing resistance of BA.4 and BA.5 to the virulence-neutralizing Abs, vaccinees will now rapidly become more susceptible to virulence."

He has no doubts...
 

Zoner

Veteran Member

This article by GVB is too scientific for me. But I will quote this:

"C-19 mass vaccination has transformed the globe into a breeding ground for more and more infectious pandemics.

The list of starting/ ongoing pandemics is only growing (see fig. 2). The impact of these pandemics on individual, global and animal health has already been discussed.

Although all these pandemics will primarily generate disease in unvaccinated (parts of the) population(s) [see fig. 1], the latter should not be vaccinated because vaccination, especially with non-replicating viral vaccines, will only enhance immune escape and increase the likelihood for vaccinated individuals to contract ADEI or even ADED."
 
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Zoner

Veteran Member
Although all these pandemics will primarily generate disease in unvaccinated (parts of the) population(s) [see fig. 1], the latter should not be vaccinated because vaccination, especially with non-replicating viral vaccines, will only enhance immune escape and increase the likelihood for vaccinated individuals to contract ADEI or even ADED."
So he is saying that the unvaccinated will not be immune to further pandemics. But to get into good health, have plenty of antivirals including ivermectin, and stay away from crowds. We are living in a 'sick world' literally speaking.
 

Tristan

Has No Life - Lives on TB
(fair use applies)

England: Excess Deaths on the Rise But NOT Because of COVID – Experts Call for Investigation
By Jim Hoft
Published July 6, 2022 at 9:25pm

The death toll in England and Wales continues to rise, even though Covid-related deaths have dropped.

As a result, health experts have requested an immediate investigation into the source of the rising non-Covid excess death.

Recent data from the Office for National Statistics (ONS) showed 1,540 excess deaths in the week ending on June 24. However, only about 10% of those deaths were caused by Covid-19, the Telegraph reported.

Health experts are still looking for answers and have called for an urgent investigation. They believed that the pandemic response, lack of access to healthcare, and even the cost of living crisis might be to blame.

“Before the end of March, deaths in England and Wales were lower than usual this year despite hundreds of people dying from Covid. Yet in the last three months, the situation has reversed, with overall deaths rising even though Covid deaths have been falling,” the news outlet added.

We’ve reached the excess deaths are on the rise but not because of covid stage of the pandemic Excess deaths are on the rise – but not because of Covid
— Frank Grimes Jr. (@FrankGrimes_Jr) July 6, 2022

More from Telegraph:

‘The reality is going to be quite complex’
Prof Paul Hunter, professor in medicine, at the University of East Anglia, said some of the excess could be people whose health was weakened by Covid. The infection is known to increase the risk of stroke and heart attacks. But he warned that there may be other more complex factors at play.
“Some might also be down to other impacts of the pandemic, such as problems in accessing health care, delayed referrals for treatment and then things related to the restrictions we lived under, such as reduced activity and sedentary lives,” he said.
“I think the reality is going to be quite complex but it’s something we do need to be aware of and actually try and understand.
“We know there is a relationship between excess deaths and deprivation so maybe the current financial situation we are in is exacerbating that.
“There is despair from your livelihood disappearing up the swanny. It doesn’t have to lead to suicide, chronic stress can lead to all sorts of problems.”
Dr Charles Levinson, the chief executive of the private GP company DoctorCall, also called for a government inquiry into what was causing so many deaths at home.
The ONS reported 752 excess deaths in the home in the latest week, 30 per cent more than usual, and more than hospitals and care homes put together.
“This is exactly why a proper government investigation is required,” he said. “This is not just displacement from hospitals… I do not understand how this is not being properly discussed.”
Dr Levinson added: “The reasons behind these horrific numbers are complicated and none of us fully understand them, so that is exactly why there should be an urgent and comprehensive Government inquiry.
“If anything, the situation seems to be worsening. Considering the relentless focus on one virus for more than two years, requesting answers from Government on thousands and thousands of non-Covid excess deaths is entirely reasonable.”

The Gateway Pundit previously reported that there has been a shocking spike in unexplained deaths reported in the past year among teenagers and young adults.

Below is the list of articles reported by so-called health experts to explain the recent spike in “Sudden Arrhythmic Death Syndrome” (SADS).

Notice what DIDN’T make the list!

The US Sun: Urgent warning to gardeners as soil ‘increases risk of killer heart disease’
  • “Medics found that pollutants in the soil could have a ‘detrimental effect on the cardiovascular system’. Writing in Cardiovascular Research, a journal of the European Society of Cardiology, the authors said soil pollutants include heavy metals, pesticides, and plastics. They state that contaminated soil could then lead to increasing oxidative stress in the blood vessels, which in turn leads to heart disease. Dirty soil can get into the blood stream, through inhalation.”
Daily Mail: Expert warns that shoveling snow can be a deadly way to discover underlying cardiovascular conditions as straining the heart with physical activity could cause sudden death
  • “Dr John Bisognano, head of preventive cardiology at the University of Michigan Health Frankel Cardiovascular Center, warned that people who live stagnant lives could end up straining themselves to the point of death while shoveling snow. ‘Many people haven’t done a lot of exercise for the rest of the year and shoveling snow is not only a heavy exercise, but an exercise that really stresses the entire cardiovascular system,’ Bisognano said in a university release.
Wales Online: Energy bill price rise may cause heart attacks and strokes, says TV GP
  • “A doctor has warned that today’s huge hike in gas and electricity prices for 22million homes across the Uk could mean a rise in heart attacks and strokes. Dr Amir Khan spoke out on ITV’s Lorraine this morning, as he fears the huge new bills will have a devastating effect on people’s health. As a doctor, he said he knows he will see the effects on patients attending his GP practice.”
Wales Online: Sweating more than usual and at night could be a sign of heart attack
  • “Sweating more than usual could be a sign of an impending heart attack, experts say. Night sweats are also a sign for women that they have heart issues. It’s well-known that heart attacks can be life-threatening and the sight of someone in a TV drama clutching their chest as they struggle for breath is a common one. However, in real life there are several early warning signs to be aware of.”
Health Line: Can Snoring Lead to Heart Failure?
  • “Snoring is not only a noisy nuisance — it may also be a sign of sleep apnea. Not everyone who snores has this underlying condition. For those who do, snoring can lead to heart failure.”
CBS News: Watching less TV can reduce heart disease risk, research suggests
  • “A new study finds that if we could limit our daily television viewing, we could reduce our risk of heart disease. They found that people who watched more than four hours of TV a day were at the greatest risk of developing heart disease while those who watched less than an hour of TV a day had a 16-percent lower rate. Interestingly, time spent using a computer did not appear to influence heart disease risk.”
Daily Mail: Entirely new kind of ‘highly reactive’ chemical is found in Earth’s atmosphere – and it could be triggering respiratory and heart diseases and contributing to global warming, scientists claim
  • “Scientists have detected a new type of extremely reactive substance in the Earth’s atmosphere that could pose a threat to human health, as well as the global climate. The research team claims that the hydrotrioxides are likely to be able to penetrate into tiny airborne particles, known as aerosols, which pose a health hazard and can lead to respiratory and cardiovascular diseases.”
The US Sun: Summer holidays warning as flight delays increase risk of silent killers
  • “Experts have now warned that the stress that builds up due to travel issues could be putting you at risk of silent killers. Superintendent pharmacist Abbas Kanani at ChemistClick said unexpected events such as grounded flights and refund issues could trigger physical changes in the body. He explained: “Holidaymakers deciding to sleep in airports, buy unhealthy meals and increase the consumption of alcohol when faced with continuous uncertainty could be at risk of high cholesterol which can lead to the life threatening condition, heart disease.”
Toronto Sun: Daylight savings may increase chance of heart disease, strokes: Studies
  • “Scientific research has found that the transition to daylight saving time, could be linked to heart disease and strokes, according to a report from the American Heart Association.”
New Scientist: Taller people may have a higher risk of nerve, skin and heart diseases
  • “Being taller may increase your risk of developing nerve, skin and some heart diseases, according to the largest study linking height and disease to date. The findings suggest that height could be used as a risk factor to prioritise screening tests for those at greatest risk of certain diseases.”
News Medical: Neighborhood ‘redlining’ may increase risk of cardiovascular diseases
  • “The historical discriminatory housing policies known as “redlining” are associated with heart disease and related risk factors today in impacted neighborhoods, more than 60 years after they were banned, according to a study published today in the Journal of the American College of Cardiology. Health disparities have been linked to a variety of socio-economic, environmental and social factors, and this study adds to growing evidence of the long-term cardiovascular impacts disparities can have on vulnerable populations.”
Medical News Today: What is the link between cold weather and heart attacks?
  • “Cold weather exposure can increase the risk of cardiac responses, including heart attacks. This is because blood vessels respond to low temperatures by constricting, which increases blood pressure and reduces circulation, putting strain on the heart.”
New York Post: Falling asleep with the TV on could bring early death: study
  • “Millions of Americans fall asleep each night in front of the TV — but a new study has found the practice could contribute to an early death. Researchers at the Northwestern University School of Medicine examined the impact of ambient light on the health and sleeping habits of 552 people between the ages of 63 and 84.”
New Scientist: Solar storms may cause up to 5500 heart-related deaths in a given year
  • “Solar storms that disrupt Earth’s magnetic field may cause up to 5500 heart-related deaths in the US in some years. The sun goes through cycles of high and low activity that repeat approximately every 11 years.”
Express: Blood clots: How do you sleep? One position may increase the risk of deep vein thrombosis
  • “Harvard Health writes: “Sleeping sitting up in a recliner […] could in some cases raise your risk of deep vein thrombosis. A blood clot in a limb can occur if your arms or legs are both bent motionless for hours. “But provided you are comfortable and can recline back slightly, there should be few risks to sleeping upright, assuming it doesn’t interfere with your ability to get a good night’s sleep.” Sleeping upright is not the only sleeping position with health risks, however. According to experts at Mayo Clinic, sleeping on the back can cause the tongue and jaw to slant down, crowding the airway.”



Maybe, just maybe - the tide is turning?
 

Heliobas Disciple

TB Fanatic
Yes, it is terrifying. Even the doctors who interview him realize his expertise and others like Dr. Malone the discoverer of the mRNA messaging system and Dr. Weinstein, Dr. Jonathan Weissman, Dr. Paul Alexander and Dr. McCollough acknowledge his expertise.
God is present for those needing the peace only Jesus can provide. "Peace I leave with you, My peace I give to you; not as the world gives do I give to you. Let not your heart be troubled, neither let it be afraid."
The world as I see it is in the beginning of great troubles and tribulation.
"The Lord is my Refuge and strength, a very present Help in trouble." -Psalm 46

I think he's getting more frustrated, and more worried. In one of the more recent interviews he commented that he may not 'published' doctor but he was working on patents not publishing and yes, he was 'only a vet' but then went through his GAVI and Gates foundation background. So I think those must be the responses he's been getting when the medical establishment dismisses his warnings. I think that is unfair and dangerous because he has more experience and more knowledge than all of them put together/my words, not his. We've seen with some of the substacks that non-medical people are smarter and more aware of what's going on than the average doctor, FOR SURE, and more knowledge than Fauci and Walenski and the more vocal, tv type 'authorities' who everyone looks up to and spew nonsense. I am continually impressed with the substack content, all of those writers are heros in my book.

HD
 

Heliobas Disciple

TB Fanatic

This article by GVB is too scientific for me. But I will quote this:

"C-19 mass vaccination has transformed the globe into a breeding ground for more and more infectious pandemics.

The list of starting/ ongoing pandemics is only growing (see fig. 2). The impact of these pandemics on individual, global and animal health has already been discussed.

Although all these pandemics will primarily generate disease in unvaccinated (parts of the) population(s) [see fig. 1], the latter should not be vaccinated because vaccination, especially with non-replicating viral vaccines, will only enhance immune escape and increase the likelihood for vaccinated individuals to contract ADEI or even ADED."

that link is dead (says page not found when I click on it), I see it came from an email. Do you have another link to that article? I like to read everything he puts out, even if I only understand 1/4 of it ;)

HD
 

Heliobas Disciple

TB Fanatic
So he is saying that the unvaccinated will not be immune to further pandemics. But to get into good health, have plenty of antivirals including ivermectin, and stay away from crowds. We are living in a 'sick world' literally speaking.

In the interview with Dr. McMillan he touched on this too and I thought it didn't match up with what he had been saying so I'm glad it's all coming together. What he said was that the vaccinated for Covid won't be protected from the next serious covid mutation, but they will be protected from flu and monkeypox because one of their antibodies is elevated (I forget which one now, t cells or killer cells or innate ?, it's really all confusing to a non-scientist, I try to get the big picture and not get caught in the weeds). But because of that elevation (that won't help them with covid) as a group they are stronger for other viruses and he expects to see worse outbreaks of monkeypox in the unvaxxed areas.

And he does repeat now that the unvaxxed can still get sick (with Covid as well as the other diseases) but that they have a stronger immune system now after defeating covid and they will probably not get very sick but to be safer, stay away from crowded indoor places.

I have my own theory - and that's because at one point in my youth I worked as a server in a fancy restaurant - and let me tell you, those dishwashers shouldn't be called dishwashers, they should be called dirty water circulators. It was disgusting. So I think one of the reasons covid numbers went back up when restaurants went back was not only due to everyone sitting on top of each other, but because they were sharing silverware and glasses (and to a lesser degree dishes since those may get the circulating water but lips don't touch them) that weren't truly sanitized. We started going out to restaurants (not often, maybe once or twice a month) and I bring my own plastic utensils (I have a ton of them from the last two years of to-go orders that are nicely wrapped) and don't order anything to drink. Those cups are nasty, I suppose if I really need a drink I'd ask for my water in a to-go cup. I also wear nitrile gloves when I go in and am handed the menu, and don't take them off until I return the menu to the server. Tons of germs on those menus too. They do not get wiped down between customers. I know this sounds excessive, but if covid gets worse or monkeypox hits your area and you are determined to still eat out, it will help you if you follow those easy steps;).

HD
 
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