MNKYPOX Mpox (Monkeypox) clade 1b International Emergency Thread

phloydius

Veteran Member
Continuation of thread: HEALTH - Monkeypox - more bad news

From that thread:
  • Sweden detects first case of Mpox clade 1 (Post #900)
  • Pakistan Detects 3 Mpox cases from UAE arrivals (Post #1004)
  • China to screen arrivals for Mpox (Post #1009)
  • Found in the Congo (DRC), Burundi, Rwanda, Uganda, CAR, Cote d’Ivoire, Cameroon, Ghana, Liberia, Nigeria, South Africa, and Kenya.
When looking up information on Monkeypox use the date and clade to determine which version the article is referencing. There are many differences between the 3 versions/clades.

In General --

Mpox clade 2 is the less deadly harder to transmit version of Monkeypox (and the one from the 2022 outbreak).

Mpox clade 1 is the more deadly easier to transmit version of Monkeypox from the Congo (DRC).

Mpox clade 1b is a new variant (discovered in Apr 2024) that is reported to be even easier to transmit via air and more casual touch than clade 1 that is currently spreading.


Because Mpox clade 2 was harder to transmit, it stayed primarily focused in the homosexual communities because that is where it first spread internationally. Mpox clade 1b spreads easier and is hitting children hard in the DRC because they play together. Children under the age of 15 represent 70% of the Mpox clade 1b cases and 85% of deaths in the Congo.

In Africa clade 2 had a mortality rate of around 1% (which fell to 0.2% outside of Africa in 2022); whereas in the past clade 1 has often been quoted with a mortality rate of 10%. In the most recent outbreak in Congo, which is a mixture of clade 1 and clade 1b, the mortality rate is just above 5% and about 10% require hospitalization.

  • Please keep this thread to serious news, preparation & discussion.
  • Please no memes. Here is the meme thread:

[Please note that I started the thread for helen, but this is HER thread. Not mine.]
 
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phloydius

Veteran Member
For the first few infectious days, Monkeypox may be mistaken for a cold, covid, or the flu.
Patient become infectious to others at the very first sign of symptoms, typically via airborne transmission.

Transmission methods (in general order of ease of contracting Mpox clade 1b):

Close physical contact, coming in direct contact with puss, improperly cooked infected meat, kissing, infected clothing or bedding, skin to skin contact without blisters, cough moisture, sweat, other fomites (infected objects), sustained moist infected air.​

Information for Clade 2, modified for what I have been able to find for Clade 1 & 1b, but it is very early still:

Simple Summary
Early Symptoms: Cough, sore throat, fever, headache, muscle & back pain, fatigue, chills, swollen lymph nodes
Middle Symptoms: Painful rash & pimples
Later Symptoms: Sores that resemble blisters & abscesses
Final Symptoms: Score scab over, dry, and fall off

Detailed Summary
Day 0: Infection Date
+4-17 Days: Start of first symptom (Mean of 8 Days)
+3-7 Days : Flu/Covid like symptoms
+7-21 Days: Rash/Blister symptoms phase
+30-60 Days: Ultra Severe cases (Rash/Blister Phase)


First Symptoms (for 1-3 Days): light dry cough, tickle in the throat (caused by infectious sores lower in the throat).

Second Symptoms (for 2-4 Days): Worse cough, hacking, shortness of breath, turn into flu-like tiredness & body aches, slight headache, loss of concentration. Sores or ulcers in the throat and mouth (may be very small and hard to see), chills, mild fever (99F-100F), enlarged lymph nodes.

Third Symptoms(1-3 Days): A flat red rash may appear on the face (1990's outbreak), or near the site of infection and face (outbreak in 2022), or the face, hands, and chest (clade 1), or areas covered by clothing (clade 1b). In clade 1b this stage will look very similar to chicken pox or shingles (but is not related). Some people skip this step entirely, or it may last only a few hours.

Fourth Symptoms: Red inflamed bump similar to a bug bite or pimple in body-wide random locations (not isolated to only one part of the body) or small round weeping wound with a white border. Sores in full digestive track that may cause blood or puss in stool. Increase in fever (up to 103F). Tiredness, body aches, and headaches become severe.

Fifth Symptoms: Inflamed bumps turn into blister-like, or syphilis-like oozing wounds. Severe itching. Wounds in the mount may make eating painful. Wounds turn deeper with a thicker wound edge. Fever (up to 104F). Morphine may not eliminate severe pain in more severe cases.

Final Phase (Recovery or Death): Recovery -- Fever & headache start reducing in severity. Wounds start to regress and itches starts to lessen over several weeks. Stay very weak & tired with lagging cough.


Note: This information is based on subjective reports on social media from [the 2022 outbreak] patients as well as official information, and some new information coming for clade 1 & 1b. It is entirely possible that there are errors, and is the information to the best of my knowledge -- but should NOT be considered medical advice!


------------

Chickenpox (varicella virus) is a herpes virus.
Smallpox (variola), Cowpox (vaccinia), horsepox (HSPV), and monkeypox (MPXV) are all Orthopoxviruses.

Having a vaccine for any of the Orthopoxviruses, provides at least some protection for all the other Orthopoxviruses. Having Chickenpox provides no protection for any Orthopoxviruses.

Companies that recently developed a monkeypox vaccine: Bavarian Nordic (Imvanex/Jynneos), Emergent BioSolutions (ACAM2000), [and smallpox antiviral] Chimerix (Tembexa), (Imvamune). Tonix Pharmaceuticals is developing a vaccine.
 
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phloydius

Veteran Member

WHO Director-General declares mpox outbreak a public health emergency of international concern​


14 August 2024 News release Reading time: 3 min (789 words)

WHO Director-General Dr Tedros Adhanom Ghebreyesus has determined that the upsurge of mpox in the Democratic Republic of the Congo (DRC) and a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the International Health Regulations (2005) (IHR).

Dr Tedros’s declaration came on the advice of an IHR Emergency Committee of independent experts who met earlier in the day to review data presented by experts from WHO and affected countries. The Committee informed the Director-General that it considers the upsurge of mpox to be a PHEIC, with potential to spread further across countries in Africa and possibly outside the continent.

The Director-General will share the report of the Committee’s meeting and, based on the advice of the Committee, issue temporary recommendations to countries.

In declaring the PHEIC, Dr Tedros said, "The emergence of a new clade of mpox, its rapid spread in eastern DRC, and the reporting of cases in several neighbouring countries are very worrying. On top of outbreaks of other mpox clades in DRC and other countries in Africa, it’s clear that a coordinated international response is needed to stop these outbreaks and save lives.”

WHO Regional Director for Africa Dr Matshidiso Moeti said, “Significant efforts are already underway in close collaboration with communities and governments, with our country teams working on the frontlines to help reinforce measures to curb mpox. With the growing spread of the virus, we’re scaling up further through coordinated international action to support countries bring the outbreaks to an end.”

Committee Chair Professor Dimie Ogoina said, “The current upsurge of mpox in parts of Africa, along with the spread of a new sexually transmissible strain of the monkeypox virus, is an emergency, not only for Africa, but for the entire globe. Mpox, originating in Africa, was neglected there, and later caused a global outbreak in 2022. It is time to act decisively to prevent history from repeating itself."

This PHEIC determination is the second in two years relating to mpox. Caused by an Orthopoxvirus, mpox was first detected in humans in 1970, in the DRC. The disease is considered endemic to countries in central and west Africa.

In July 2022, the multi-country outbreak of mpox was declared a PHEIC as it spread rapidly via sexual contact across a range of countries where the virus had not been seen before. That PHEIC was declared over in May 2023 after there had been a sustained decline in global cases.

Mpox has been reported in the DRC for more than a decade, and the number of cases reported each year has increased steadily over that period. Last year, reported cases increased significantly, and already the number of cases reported so far this year has exceeded last year’s total, with more than 15 600 cases and 537 deaths.

The emergence last year and rapid spread of a new virus strain in DRC, clade 1b, which appears to be spreading mainly through sexual networks, and its detection in countries neighbouring the DRC is especially concerning, and one of the main reasons for the declaration of the PHEIC.

In the past month, over 100 laboratory-confirmed cases of clade 1b have been reported in four countries neighbouring the DRC that have not reported mpox before: Burundi, Kenya, Rwanda and Uganda. Experts believe the true number of cases to be higher as a large proportion of clinically compatible cases have not been tested.

Several outbreaks of different clades of mpox have occurred in different countries, with different modes of transmission and different levels of risk.

The two vaccines currently in use for mpox are recommended by WHO’s Strategic Advisory Group of Experts on Immunization, and are also approved by WHO-listed national regulatory authorities, as well as by individual countries including Nigeria and the DRC.

Last week, the Director-General triggered the process for Emergency Use Listing for mpox vaccines, which will accelerate vaccine access for lower-income countries which have not yet issued their own national regulatory approval. Emergency Use Listing also enables partners including Gavi and UNICEF to procure vaccines for distribution.

WHO is working with countries and vaccine manufacturers on potential vaccine donations, and coordinating with partners through the interim Medical Countermeasures Network to facilitate equitable access to vaccines, therapeutics, diagnostics and other tools.

WHO anticipates an immediate funding requirement of an initial US$ 15 million to support surveillance, preparedness and response activities. A needs assessment is being undertaken across the three levels of the Organization.

To allow for an immediate scale up, WHO has released US$ 1.45 million from the WHO Contingency Fund for Emergencies and may need to release more in the coming days. The Organization appeals to donors to fund the full extent of needs of the mpox response.


----------------

Fantastic primer video as a place to get started understanding Mpox clade 1b by MedCram (posted by @cheyenneplateau ): Run time 20 mins.

Really, everyone should take the time to watch this video before commenting on this thread. It will answer most of the question you have very quickly. The video is not perfect, but has a huge amount of quick information.

View: https://www.youtube.com/watch?v=WRqm2-0_RyY
 
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phloydius

Veteran Member
Detailed article on Fomites: Post #1159

Useful articles on prior smallpox vaccinations and monkeypox: Post #1063

A Recipe from @Tigerlily for Skin Comfort Blend: Post #1118

Link to the National Wastewater Surveillance System (NWSS) Originally posted by @Seeker22 :

"The overall degree of environmental contamination was compared across days of sampling." Shows 100% of air samples positive. Study posted by @helen : Post #964

Colloidal Silver Stops Monkeypox - Article w/ studies. Posted by @Seeker22 : Post #992

Article on Fauci's Mpox gain-of-function, posted by @helen : Post #881

Study suggesting Monkeypox can be spread by mosquitoes: Post #741

Quotes from Study on Monkeypox spread by fomites 15 days after infected patient left: Post #24

Long boring article on rise of clade 1 and speculation of mutations in Apr 2024: Post #191

Discovery of clade 1b: Post #197

Article on emergence of clade 1b with mutations listed: Post #216

Great timeline of the 2022 outbreak w/ article on clade 1b spreading rapidly without sexual contact (timeline is 7 posts long): Post #332
 
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Meemur

Voice on the Prairie
Quick reminder: if you live in or around a college town or major university, be aware of the start dates and consider doing major shopping before "move-in day/weekend."

Ditto getting haircuts, dental work, or other services that require close contact.

At schools like University of Iowa, Iowa State, and even the community colleges, students come from all over the globe. Packy and I still think we had Covid before anyone here knew what it was.
 
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Kennori

Senior Member
Everybody take 3 deep cleansing breaths. MP is a dermatologic condition usually found in the alternative sexual crowd. {I'm trying to be nice here}. Unless someone manufactured another super-infective GOF-chimera like they did Covid normal people with normal sexual proclivities should rarely see this disease. Think Venereal warts on steroids. Notice the scare tactics similar to 2020 right before the election. Have we not learned that the WHO and the ID/Pharmaceutical community have an agenda that brings them money, control, and population reduction? Are we really that gullible to fall for this again so soon? Turn off your TV, do not listen to commercial radio, ignore any PSA's mentioning MP, find a source for Ivermectin, Hydroxchloroquine, Vitamin D3, and Doxycycline.
 

mom2many

Veteran Member
Everybody take 3 deep cleansing breaths. MP is a dermatologic condition usually found in the alternative sexual crowd. {I'm trying to be nice here}. Unless someone manufactured another super-infective GOF-chimera like they did Covid normal people with normal sexual proclivities should rarely see this disease. Think Venereal warts on steroids. Notice the scare tactics similar to 2020 right before the election. Have we not learned that the WHO and the ID/Pharmaceutical community have an agenda that brings them money, control, and population reduction? Are we really that gullible to fall for this again so soon? Turn off your TV, do not listen to commercial radio, ignore any PSA's mentioning MP, find a source for Ivermectin, Hydroxchloroquine, Vitamin D3, and Doxycycline.
Sorry, but did you read the other thread or even up this thread? Fauci's group has been working on this virus since 2015, trying to make it easier to spread and more deadly isn't that GOF? Also, as noted above, the virus lives on surfaces or fomites, you can also get it if exposed to someone sneezing or coughing.

And yes, those of us who have been watching this with Helen since 2020 understand it is probably ONLY a scare tactic but it really is spreading in Africa, there really are volunteers that work in those countries be they doctors, religious missionaries and others who travel there for whatever reason , they eventually have to go home and they travel by air.

I don't mean to be short tempered or rude, but I have a migraine today and am really tired of people who haven't been following this jumping in and telling us to calm down. Thank you for adding the meds you think might help, we can add them to the list.
 

Seeker22

Has No Life - Lives on TB
Everybody take 3 deep cleansing breaths. MP is a dermatologic condition usually found in the alternative sexual crowd. {I'm trying to be nice here}. Unless someone manufactured another super-infective GOF-chimera like they did Covid normal people with normal sexual proclivities should rarely see this disease. Think Venereal warts on steroids. Notice the scare tactics similar to 2020 right before the election. Have we not learned that the WHO and the ID/Pharmaceutical community have an agenda that brings them money, control, and population reduction? Are we really that gullible to fall for this again so soon? Turn off your TV, do not listen to commercial radio, ignore any PSA's mentioning MP, find a source for Ivermectin, Hydroxchloroquine, Vitamin D3, and Doxycycline.

First, please take time to watch the MedCram video. Scroll down on link to find that.

HEALTH - Mpox (Monkeypox) clade 1b International Emergency Thread

That will get you up to speed on what Mpox is and isn't. Very informative and worth your time.

Then, read this one:

Fauci’s institute hid mpox gain-of-function plans from Congress and the media

This ain't last year's Monkey Pox. They changed the game.
 

helen

Panic Sex Lady
Everybody take 3 deep cleansing breaths. MP is a dermatologic condition usually found in the alternative sexual crowd. {I'm trying to be nice here}. Unless someone manufactured another super-infective GOF-chimera like they did Covid normal people with normal sexual proclivities should rarely see this disease. Think Venereal warts on steroids. Notice the scare tactics similar to 2020 right before the election. Have we not learned that the WHO and the ID/Pharmaceutical community have an agenda that brings them money, control, and population reduction? Are we really that gullible to fall for this again so soon? Turn off your TV, do not listen to commercial radio, ignore any PSA's mentioning MP, find a source for Ivermectin, Hydroxchloroquine, Vitamin D3, and Doxycycline.
You need to read more on this subject before you post.
 

packyderms_wife

Neither here nor there.
Quick reminder: if you live in or around a college town or major university, be aware of the start dates and consider doing major shopping before "move-in day/weekend."

Ditto getting haircuts, dental work, or other services that require close contact.

At schools like University of Iowa, Iowa State, and even the community colleges, students come from all over the globe. Packy and I still think we had Covid before anyone here knew what it was.

This^^^ And unfortunately I've been so busy that I forgot that this weekend was move in weekend for the majority of the students, which means last weekend was move in weekend for Int'l students.
 

greysage

Gold Level Member
Quick reminder: if you live in or around a college town or major university, be aware of the start dates and consider doing major shopping before "move-in day/weekend."

Already here. My med student neighbors (brothers, Dr. Dad got them a place to live for their uni time.) They and their fellow students study and eat together at all hours. Our local Olympic womens rugby player is back in town parading around (deservedly) and who knows what she may have come back with. May be interesting living between the international airport, university hospital, and three college campuses if they are bringing disease with them!
 

packyderms_wife

Neither here nor there.
Good Lord.
Aren’t there thousands upon thousands gathered there at any given time?

Let this sink in.

Contact tracing has begun for those on the plane he took “from Saudi Arabia”…

yes, not including inside of the "shrine" there's typically a half million or more on the outside that are not able to gain access to that big black stone and walk around it.
 

psychgirl

TB Fanatic
Sorry, but did you read the other thread or even up this thread? Fauci's group has been working on this virus since 2015, trying to make it easier to spread and more deadly isn't that GOF? Also, as noted above, the virus lives on surfaces or fomites, you can also get it if exposed to someone sneezing or coughing.

And yes, those of us who have been watching this with Helen since 2020 understand it is probably ONLY a scare tactic but it really is spreading in Africa, there really are volunteers that work in those countries be they doctors, religious missionaries and others who travel there for whatever reason , they eventually have to go home and they travel by air.

I don't mean to be short tempered or rude, but I have a migraine today and am really tired of people who haven't been following this jumping in and telling us to calm down. Thank you for adding the meds you think might help, we can add them to the list.
Thank you
 

TheSearcher

Are you sure about that?
Everybody take 3 deep cleansing breaths. MP is a dermatologic condition usually found in the alternative sexual crowd. {I'm trying to be nice here}. Unless someone manufactured another super-infective GOF-chimera like they did Covid normal people with normal sexual proclivities should rarely see this disease. Think Venereal warts on steroids. Notice the scare tactics similar to 2020 right before the election. Have we not learned that the WHO and the ID/Pharmaceutical community have an agenda that brings them money, control, and population reduction? Are we really that gullible to fall for this again so soon? Turn off your TV, do not listen to commercial radio, ignore any PSA's mentioning MP, find a source for Ivermectin, Hydroxchloroquine, Vitamin D3, and Doxycycline.
I just read summary from the Houston Chronicle: We've been watching Mpox for a few years now, and the recent case rate is trending below previous years.

Given that the Chronicle is so left it spins like a woke top, this is the WHO causing trouble. Not a serious concern for those people who practice normative lifestyles and hygiene.

Don't let these bastards scare you. Wash your hands and avoid random buggery.
 
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