I did a google search to see if it was real or not, because I couldn't remember any of that happening. In the movie 60 million die world wide.
MNKYPOX Monkeypox - Consolidated Thread.
- Thread starter Tigerlily
- Start date
psychgirl
Has No Life - Lives on TB
There’s two variances. I meant to say that earlier, but I’m no expert lol :
Congo
West African
I “think” the one going around now is the West African variance which is less lethal.
SouthernBreeze
Has No Life - Lives on TB
Correct. IIRC, it only has a 1% mortality rate.
Valann
Contributing Member
From an infectious disease website I have followed for many years-
"
communicated by:
ProMED
[Interestingly, the diagnosis of monkeypox as the West African clade was confirmed by PCR in the UK on 6 May 2022 (NCDC: 15 monkeypox cases confirmed in 2022 | TheCable). This is an important finding because the West African clade is less pathogenic than the Central African clade, with little or no mortality. - Mod.TY]
******
[2] Portugal, Spain, UK: update
Date: Wed 18 May 2022 16:19 BST
Source: Daily Mail [abridged, edited]
Monkeypox hits Europe: Now Portugal and Spain detect virus in men
- 1st signs of global outbreak of rare disease as Portugal, UK, Spain, all find cases
- Experts fear disease is spreading in communities for 1st time, going undetected
- US health officials are monitoring 6 Americans who were in contact with case
Monkeypox has now been spotted in Portugal and Spain, in what could be the first global outbreak of the rare disease.
Spain is monitoring 8 men who it believes are infected, with tests being carried out to confirm they have the virus. All of the men are gay or bisexual, according to local media, and most were detected at STI [sexually transmitted infection] clinics in Madrid.
In Portugal, 5 men have also tested positive and at least 15 more cases are being investigated, health officials there said today. These cases are all male and mostly 'young' -- but it is not yet clear how they caught the virus.
Until now, monkeypox cases were confined to travellers and their relatives returning from western and central Africa, where the virus is endemic. But experts now fear it is spreading more widely for the 1st time after 7 Britons were diagnosed in the past fortnight. In the UK, 6 of them appear to have been infected and the majority are not linked, which suggests more cases are going undetected. Health chiefs are scrambling to find the source of the cases.
Of the British patients, 4 are gay or bisexual men, and officials say the pattern of transmission is 'highly suggestive of spread in sexual networks'.
Regions across Spain have been put on alert following the announcement of 8 suspected cases in Madrid. Confirmation is still awaited from the National Centre for Microbiology but health chiefs say 'great care must be taken.' The country's top public health doctor, Fernando Simón, said 'it is not likely that monkeypox will generate a significant transmission but it cannot be ruled out'. The Spanish health alert system has called on communities to notify public health services 'urgently' of patients with symptoms. He said it was now necessary to take extreme surveillance measures and investigate all the hypotheses about the routes of contagion.
Meanwhile, the suspected cases in Portugal were all detected in the Lisbon and Tagus Valley region. The men are said to be 'stable' and all suffering from 'ulcerative lesions', one of the tell-tale signs of the virus. Portugal's health ministry has issued a warning urging people with lesions and rashes to see a doctor. When these symptoms appear, 'direct physical contact' should be avoided, officials added.
Until now monkeypox had only ever been detected in 4 countries outside of Africa -- the UK, US, Israel, and Singapore. All of the cases had travel links back to Nigeria and Ghana. Infections are more common in central and western Africa, where they can result from direct contact with infected animals.
An expert from the UK Health Security Agency said the latest UK cases 'appear to have acquired the infection via sexual contact'. Dr Mateo Prochazka, who leads the UKHSA team which is investigating monkeypox, described this route of transmission as 'novel'. In England, 7 people have been diagnosed with the virus over the past 2 weeks, 5 of which are in London. Of these, 4 are gay or bisexual men, and only one has recent travel links to a country where the virus is endemic, which is 'highly suggestive' of spread in 'sexual networks', Dr Prochazka added.
Writing on Twitter, he said: '... the high proportion of cases in the current outbreak in England that are gay or bisexual (4/7, 57%) is highly suggestive of spread in sexual networks. This is further suggested by the fact that common contacts have been identified for only 2 of the 4 latest cases.' Other experts said further research is necessary before it will be possible to conclude if the virus is sexually transmissible.
Monkeypox can kill up to one in 10 people who get it but the new cases have the West African variant, which is deadly for around one in 100. Initial symptoms include fever, headache, muscle aches, backache, swollen lymph nodes, chills, and exhaustion. A rash can develop, often beginning on the face, then spreading to other parts of the body including the genitals. The rash changes and goes through different stages, and can look like chickenpox or syphilis, before finally forming a scab, which later falls off.
UK Health Security Agency (UKHSA) bosses have now written to regional NHS teams telling them to stock up on PPE and be on alert for patients with a new rash.
UK health chiefs say the risk to the UK population is low. But they have urged gay, bisexual, and other men who have sex with men to be extra vigilant because they appear to be at higher risk of catching it. These groups have been urged to look out for any unusual rashes or lesions on any part of their body, especially their genitalia, and to contact a sexual health service without delay if they have concerns.
Most scientists believe the outbreak will be small and transmission nothing like the levels seen with COVID. This is because monkeypox is poor at spreading between humans and relies on very close and prolonged contact between people.
[byline: Connor Boyd, Rita Sobot]
--
communicated by:
ProMED from HealthMap Alerts
[The monkeypox (MPX) outbreaks in Spain, Portugal, and the UK are highly unusual. Most of the infected individuals had not traveled to MPX virus endemic countries so their infections must have been acquired locally. Although cases of person-to-person transmission have been reported, particularly among healthcare workers attending MPX cases, chains of transmission occurring simultaneously in 3 different locations is novel. Sexual transmission has not been suspected before. As the reports above indicate, transmission through sexual intercourse has not been proven in these cases and other behaviors involving close physical contact may have been involved. It will be interesting to learn if additional cases are confirmed in any of the 3 countries in the coming days. - Mod.TY "
promedmail.org
"
communicated by:
ProMED
[Interestingly, the diagnosis of monkeypox as the West African clade was confirmed by PCR in the UK on 6 May 2022 (NCDC: 15 monkeypox cases confirmed in 2022 | TheCable). This is an important finding because the West African clade is less pathogenic than the Central African clade, with little or no mortality. - Mod.TY]
******
[2] Portugal, Spain, UK: update
Date: Wed 18 May 2022 16:19 BST
Source: Daily Mail [abridged, edited]
Monkeypox hits Europe: Now Portugal and Spain detect virus in men
- 1st signs of global outbreak of rare disease as Portugal, UK, Spain, all find cases
- Experts fear disease is spreading in communities for 1st time, going undetected
- US health officials are monitoring 6 Americans who were in contact with case
Monkeypox has now been spotted in Portugal and Spain, in what could be the first global outbreak of the rare disease.
Spain is monitoring 8 men who it believes are infected, with tests being carried out to confirm they have the virus. All of the men are gay or bisexual, according to local media, and most were detected at STI [sexually transmitted infection] clinics in Madrid.
In Portugal, 5 men have also tested positive and at least 15 more cases are being investigated, health officials there said today. These cases are all male and mostly 'young' -- but it is not yet clear how they caught the virus.
Until now, monkeypox cases were confined to travellers and their relatives returning from western and central Africa, where the virus is endemic. But experts now fear it is spreading more widely for the 1st time after 7 Britons were diagnosed in the past fortnight. In the UK, 6 of them appear to have been infected and the majority are not linked, which suggests more cases are going undetected. Health chiefs are scrambling to find the source of the cases.
Of the British patients, 4 are gay or bisexual men, and officials say the pattern of transmission is 'highly suggestive of spread in sexual networks'.
Regions across Spain have been put on alert following the announcement of 8 suspected cases in Madrid. Confirmation is still awaited from the National Centre for Microbiology but health chiefs say 'great care must be taken.' The country's top public health doctor, Fernando Simón, said 'it is not likely that monkeypox will generate a significant transmission but it cannot be ruled out'. The Spanish health alert system has called on communities to notify public health services 'urgently' of patients with symptoms. He said it was now necessary to take extreme surveillance measures and investigate all the hypotheses about the routes of contagion.
Meanwhile, the suspected cases in Portugal were all detected in the Lisbon and Tagus Valley region. The men are said to be 'stable' and all suffering from 'ulcerative lesions', one of the tell-tale signs of the virus. Portugal's health ministry has issued a warning urging people with lesions and rashes to see a doctor. When these symptoms appear, 'direct physical contact' should be avoided, officials added.
Until now monkeypox had only ever been detected in 4 countries outside of Africa -- the UK, US, Israel, and Singapore. All of the cases had travel links back to Nigeria and Ghana. Infections are more common in central and western Africa, where they can result from direct contact with infected animals.
An expert from the UK Health Security Agency said the latest UK cases 'appear to have acquired the infection via sexual contact'. Dr Mateo Prochazka, who leads the UKHSA team which is investigating monkeypox, described this route of transmission as 'novel'. In England, 7 people have been diagnosed with the virus over the past 2 weeks, 5 of which are in London. Of these, 4 are gay or bisexual men, and only one has recent travel links to a country where the virus is endemic, which is 'highly suggestive' of spread in 'sexual networks', Dr Prochazka added.
Writing on Twitter, he said: '... the high proportion of cases in the current outbreak in England that are gay or bisexual (4/7, 57%) is highly suggestive of spread in sexual networks. This is further suggested by the fact that common contacts have been identified for only 2 of the 4 latest cases.' Other experts said further research is necessary before it will be possible to conclude if the virus is sexually transmissible.
Monkeypox can kill up to one in 10 people who get it but the new cases have the West African variant, which is deadly for around one in 100. Initial symptoms include fever, headache, muscle aches, backache, swollen lymph nodes, chills, and exhaustion. A rash can develop, often beginning on the face, then spreading to other parts of the body including the genitals. The rash changes and goes through different stages, and can look like chickenpox or syphilis, before finally forming a scab, which later falls off.
UK Health Security Agency (UKHSA) bosses have now written to regional NHS teams telling them to stock up on PPE and be on alert for patients with a new rash.
UK health chiefs say the risk to the UK population is low. But they have urged gay, bisexual, and other men who have sex with men to be extra vigilant because they appear to be at higher risk of catching it. These groups have been urged to look out for any unusual rashes or lesions on any part of their body, especially their genitalia, and to contact a sexual health service without delay if they have concerns.
Most scientists believe the outbreak will be small and transmission nothing like the levels seen with COVID. This is because monkeypox is poor at spreading between humans and relies on very close and prolonged contact between people.
[byline: Connor Boyd, Rita Sobot]
--
communicated by:
ProMED from HealthMap Alerts
[The monkeypox (MPX) outbreaks in Spain, Portugal, and the UK are highly unusual. Most of the infected individuals had not traveled to MPX virus endemic countries so their infections must have been acquired locally. Although cases of person-to-person transmission have been reported, particularly among healthcare workers attending MPX cases, chains of transmission occurring simultaneously in 3 different locations is novel. Sexual transmission has not been suspected before. As the reports above indicate, transmission through sexual intercourse has not been proven in these cases and other behaviors involving close physical contact may have been involved. It will be interesting to learn if additional cases are confirmed in any of the 3 countries in the coming days. - Mod.TY "
Home - ProMED - ProMED-mail
ProMED is the largest publicly-available surveillance system conducting global reporting of infectious diseases outbreaks. Subscribe today.
promedmail.org
TxGal
Day by day
Yep, we're in our upper 60s and got both of those. I was a military brat and had to get it several times, just wouldn't come up with the scar. DH was military right out of HS and had his cocktail.
Somewhere on another thread I'd posted an article(s) that the smallpox vax we all received still showed antibodies on blood titer decades later, and further vax was not necessary. And I believe one of those articles was by the CDC. Trying to find it now. I know I had it saved on my computer.
annieosage
Inactive
Of course because I just moved here
jward
passin' thru
Britain offers smallpox shot to some healthcare workers and others who may have been exposed as monkeypox cases spread in Europe
Today, 10:01 AM
May 19, 20222:09 PM UTC
By Jennifer Rigby
LONDON, May 19 (Reuters) - A smattering of monkeypox cases in Britain has prompted authorities to offer a smallpox vaccine to some healthcare workers and others who may have been exposed, as a handful more cases were confirmed in parts of Europe.
... There are two main strains: the Congo strain, which is more severe – with up to 10% mortality – and the West African strain, which has a fatality rate of about 1%.
... There isn't a specific vaccine for monkeypox, but a smallpox vaccine does offer some protection, a UK Health Security Agency (UKHSA) spokesperson said.
Data shows that vaccines that were used to eradicate smallpox are up to 85% effective against monkeypox, according to the World Health Organisation.
"Those who have required the vaccine have been offered it," the UKHSA spokesperson added, without disclosing specifics on how many people have been vaccinated so far.
Some countries have large stockpiles of the smallpox vaccine as part of pandemic preparedness, including the United States.
https://www.reuters.com/business/hea...pe-2022-05-19/
Britain offers smallpox shot to some healthcare workers and others who may have been exposed as monkeypox cases spread in Europe - FluTrackers News and Information
Today, 10:01 AM
May 19, 20222:09 PM UTC
By Jennifer Rigby
LONDON, May 19 (Reuters) - A smattering of monkeypox cases in Britain has prompted authorities to offer a smallpox vaccine to some healthcare workers and others who may have been exposed, as a handful more cases were confirmed in parts of Europe.
... There are two main strains: the Congo strain, which is more severe – with up to 10% mortality – and the West African strain, which has a fatality rate of about 1%.
... There isn't a specific vaccine for monkeypox, but a smallpox vaccine does offer some protection, a UK Health Security Agency (UKHSA) spokesperson said.
Data shows that vaccines that were used to eradicate smallpox are up to 85% effective against monkeypox, according to the World Health Organisation.
"Those who have required the vaccine have been offered it," the UKHSA spokesperson added, without disclosing specifics on how many people have been vaccinated so far.
Some countries have large stockpiles of the smallpox vaccine as part of pandemic preparedness, including the United States.
https://www.reuters.com/business/hea...pe-2022-05-19/
Britain offers smallpox shot to some healthcare workers and others who may have been exposed as monkeypox cases spread in Europe - FluTrackers News and Information
Luxx
Contributing Member
Homeopathic Protocol for Smallpox Infection, Remedies for All Stages
As you may know, Bill Gates continues to speak about threats of bioterrorism. In a Policy Exchange interview, he added that a future pandemic may involve smallpox infection and that this scenario is more likely than a nuclear conflict.
This disclosure has heightened interest in small pox prevention and treatment in the US.
As per the NIH, Smallpox is a Category A biological agent along with anthrax, plague, botulinum toxin, and tularemia. These category agents can potentially cause high mortality rates and pose major public health risks.
Homeopathy plays a significant role as a viable form of treatment both curative and preventative for smallpox infection according to historical records.
[I have an earlier article on that which also includes herbal remedies. I have learned quite a bit more since then, so pretty much all I have learned on smallpox is in both of these posts.]
There is no cure for smallpox in mainstream treatment, but homeopathy is known to prevent infection from developing if given during a period of up to four days after a person has been exposed to the virus.
The virus is transmitted through inhaled droplets, from contact with open lesions, or from contaminated bedding.
Smallpox is a serious infectious viral disease. Some viruses are not serious, however this one is. Historically, approximately 30-50% of smallpox cases were fatal.
Main Homeopathic Protocol for Smallpox
This covers prevention and acute care. (You may want to PRINT this –and this-out).
The incubation period is 7-17 days and the disease progresses in 4 stages which lasts approximately 3 weeks altogether.
Consider having the following medicines on hand:
The first two would be preventatively used BEFORE Stage 1 fever, headache, muscle aches: they are Aconitum 200c mixed with Bryonia 30c (taken together at the same time). This is a great medicine for when you feel like you are coming down with something and you do not know yet what it is. This could be taken every 15 minutes for the first hour depending on the severity. Then “opening it up” (lengthening the time between doses).
This CAN abort a viral infection, but doesn’t always.
The homeopathic nosodes Variolinum, made from a smallpox pustule, and Malandrinum, derived from “grease”, a similar disease of horses, have both proved highly protective against smallpox epidemics in the past. Fellger reported giving Variolinum to several hundred people, none of whom were ever attacked with smallpox. The collective experience of generations of homeopaths in the pre-vaccine era provides ample documentation that smallpox can be effectively prevented or mitigated if either of these remedies is given at the time of exposure or early in the 7-17 day incubation period. (source)
At the first sign of symptoms, homeopaths recommend Variolinum 30C, followed an hour later by Variolinum 200C, and by 1M one hour after that. Thereafter the symptom picture must be allowed to develop to provide more definite indications.
(You could continue using Aconitum 200/Bryonia 30 and Variolinum 30c every few hours.)
Homeopathy can help people protect themselves by using Variolinum 200c in advance. It can be taken twice daily for a few days in advance for the potential of getting sick. Once you know what the incubation period is, you know someone who had it and you were exposed, then you know what is approximately the amount of time that you are going to get it.
If you don’t know what the timetable is, then you could take Variolinum 200c once a week for several weeks.
Sarracenia purpura 30c or 200 ck. This is for any stage with fever, backache, headache, sore bones, throbbing pains, photophobia, etc. Take 5 drops in half cup of water three times a day.
Own these medicines (there are others, but these perhaps are the most important):
**For the FULL PROTOCOL (including NAC) to protect from transmission from the “V” and to help those who took the “V”, go here.
You can print material on smallpox to add to your preparedness binder. >> Useful resources for this article are my first post on smallpox, a 2012 listing of useful herbs for smallpox (including patient care) and Dr. Christopher’s Herbal Legacy on Smallpox.
https://deeprootsathome.com/getting-ready-for-smallpox-natural-remedies-our-best-strategy/
As you may know, Bill Gates continues to speak about threats of bioterrorism. In a Policy Exchange interview, he added that a future pandemic may involve smallpox infection and that this scenario is more likely than a nuclear conflict.
This disclosure has heightened interest in small pox prevention and treatment in the US.
As per the NIH, Smallpox is a Category A biological agent along with anthrax, plague, botulinum toxin, and tularemia. These category agents can potentially cause high mortality rates and pose major public health risks.
Homeopathy plays a significant role as a viable form of treatment both curative and preventative for smallpox infection according to historical records.
[I have an earlier article on that which also includes herbal remedies. I have learned quite a bit more since then, so pretty much all I have learned on smallpox is in both of these posts.]
There is no cure for smallpox in mainstream treatment, but homeopathy is known to prevent infection from developing if given during a period of up to four days after a person has been exposed to the virus.
The virus is transmitted through inhaled droplets, from contact with open lesions, or from contaminated bedding.
Smallpox is a serious infectious viral disease. Some viruses are not serious, however this one is. Historically, approximately 30-50% of smallpox cases were fatal.
Main Homeopathic Protocol for Smallpox
This covers prevention and acute care. (You may want to PRINT this –and this-out).
The incubation period is 7-17 days and the disease progresses in 4 stages which lasts approximately 3 weeks altogether.
Consider having the following medicines on hand:
The first two would be preventatively used BEFORE Stage 1 fever, headache, muscle aches: they are Aconitum 200c mixed with Bryonia 30c (taken together at the same time). This is a great medicine for when you feel like you are coming down with something and you do not know yet what it is. This could be taken every 15 minutes for the first hour depending on the severity. Then “opening it up” (lengthening the time between doses).
This CAN abort a viral infection, but doesn’t always.
The homeopathic nosodes Variolinum, made from a smallpox pustule, and Malandrinum, derived from “grease”, a similar disease of horses, have both proved highly protective against smallpox epidemics in the past. Fellger reported giving Variolinum to several hundred people, none of whom were ever attacked with smallpox. The collective experience of generations of homeopaths in the pre-vaccine era provides ample documentation that smallpox can be effectively prevented or mitigated if either of these remedies is given at the time of exposure or early in the 7-17 day incubation period. (source)
At the first sign of symptoms, homeopaths recommend Variolinum 30C, followed an hour later by Variolinum 200C, and by 1M one hour after that. Thereafter the symptom picture must be allowed to develop to provide more definite indications.
(You could continue using Aconitum 200/Bryonia 30 and Variolinum 30c every few hours.)
Homeopathy can help people protect themselves by using Variolinum 200c in advance. It can be taken twice daily for a few days in advance for the potential of getting sick. Once you know what the incubation period is, you know someone who had it and you were exposed, then you know what is approximately the amount of time that you are going to get it.
If you don’t know what the timetable is, then you could take Variolinum 200c once a week for several weeks.
Sarracenia purpura 30c or 200 ck. This is for any stage with fever, backache, headache, sore bones, throbbing pains, photophobia, etc. Take 5 drops in half cup of water three times a day.
Own these medicines (there are others, but these perhaps are the most important):
- Aconitum 200
- Bryonia 30c
- Variolinum 30c
- Variolinum 200c
- Sarracenia purpura 30c or 200 ck (you can use 1000ck in the same way)
**For the FULL PROTOCOL (including NAC) to protect from transmission from the “V” and to help those who took the “V”, go here.
You can print material on smallpox to add to your preparedness binder. >> Useful resources for this article are my first post on smallpox, a 2012 listing of useful herbs for smallpox (including patient care) and Dr. Christopher’s Herbal Legacy on Smallpox.
https://deeprootsathome.com/getting-ready-for-smallpox-natural-remedies-our-best-strategy/
TxGal
Day by day
I found two links on the longevity of smallpox vaccinations (for those of us who are older). This should mean older folks wouldn't need another vax, and it would save the vax for those younger people who have never had it in the event of an outbreak:
Absence of Smallpox "Take" May Not Indicate Revaccination Failure. (centerforhealthsecurity.org)
Absence of Smallpox “Take” May Not Indicate Revaccination Failure
By Amesh A. Adalja, MD, May 6, 2011
Successful vaccination against smallpox is generally determined by inspection of the vaccine site approximately one week after vaccination. Vesicles and pustules at the site are considered to be indicative of a successful vaccine take. These lesions are due to a localized dermal infection with the vaccinia virus.
It has long been observed that people who are revaccinated have lower rates of vaccine takes. This is believed to be due to persistent immunity from prior vaccination that blocks clinical manifestation of localized vaccinia infection. However, it is not clear if the absence of a take represents vaccine failure, ie, a failure to induce immunity, or if it represents just a lack of visible evidence of a successful vaccination. Wiser and colleagues conducted a study of members of the Israeli Defense Forces (IDF) to assess the ability of surrogate immunological markers to assess vaccination results in those revaccinated against smallpox.
Surrogate Markers of Vaccine Results
This historical prospective study utilized a cohort of 159 adults, aged 24-52 years, who were vaccinated against smallpox in the winter of 2002-2003. Among the 159 subjects, 80 were included in an analysis comparing the immunologic parameters of those with and without a successful vaccination take. Important baseline characteristics are summarized in the table below.
Table: Baseline Characteristics
Immunologic Evidence of Successful Vaccination
Several immunologic parameters were assessed at day 0, day 14, and month 24. At baseline, the no-take group demonstrated higher total IgG responses, IgG1 responses, and neutralization antibody titer. This was not unexpected, given that, on average, the no-take group had been vaccinated more recently than the “take group” (the inverse correlation between total IgG level and time since vaccination was statistically significant).
At day 14, levels of IgG—including IgG1-3 subclasses—and neutralization titers were found to be higher in the take group vs. the no-take group. However, most importantly, at month 24, no difference existed in total IgG, IgG subclass, or neutralizing antibody levels between the 2 groups. Moreover, cellular interferon-gamma secretion was higher in the no-take group, and antibody avidity was similar at 23 months. No difference in vaccinia-specific B-cell numbers was found at 24 months.
Assessing Take in Re-vaccines Unnecessary?
This study demonstrates that, in the setting of re-vaccination, it is not necessary to recall those without a take (for either assessment and/or vaccination again), as a successful immunologic reaction is likely, even in the absence of evidence at the vaccination site.
This finding has major implications for mass vaccination campaigns that would occur in the event of a credible threat of smallpox release. Mass vaccination campaigns will involve the rapid mobilization of people, vaccinators, and supplies in a chaotic environment. A sizable proportion of the population has been vaccinated against smallpox in the past and may not demonstrate a vaccine take upon revaccination. Eliminating the need to assess this segment of the population for vaccine take will remove an additional task in a time of crisis and alleviate the burden on what will be already severely stressed medical resources.
Reference
Wiser I, Orr N, Smetana Z, et al. Alternative immunological markers to document successful multiple smallpox revaccinations. Clin Infect Dis 2011. 52:856-861.
And the 2nd is very, very long, so I'm just posting the link:
Immunity from Smallpox Vaccine Persists for Decades - PMC (nih.gov)
Absence of Smallpox "Take" May Not Indicate Revaccination Failure. (centerforhealthsecurity.org)
Absence of Smallpox “Take” May Not Indicate Revaccination Failure
By Amesh A. Adalja, MD, May 6, 2011
Successful vaccination against smallpox is generally determined by inspection of the vaccine site approximately one week after vaccination. Vesicles and pustules at the site are considered to be indicative of a successful vaccine take. These lesions are due to a localized dermal infection with the vaccinia virus.
It has long been observed that people who are revaccinated have lower rates of vaccine takes. This is believed to be due to persistent immunity from prior vaccination that blocks clinical manifestation of localized vaccinia infection. However, it is not clear if the absence of a take represents vaccine failure, ie, a failure to induce immunity, or if it represents just a lack of visible evidence of a successful vaccination. Wiser and colleagues conducted a study of members of the Israeli Defense Forces (IDF) to assess the ability of surrogate immunological markers to assess vaccination results in those revaccinated against smallpox.
Surrogate Markers of Vaccine Results
This historical prospective study utilized a cohort of 159 adults, aged 24-52 years, who were vaccinated against smallpox in the winter of 2002-2003. Among the 159 subjects, 80 were included in an analysis comparing the immunologic parameters of those with and without a successful vaccination take. Important baseline characteristics are summarized in the table below.
Table: Baseline Characteristics
Characteristic | “No-take” group (40) | “Take” group (40) | Total (159) |
Mean age | 33 | 34 | 35 |
Median # of prior vaccinations | 3 | 3 | 3 |
Mean interval since prior vaccination | 16 years | 19 years | 20 years |
Immunologic Evidence of Successful Vaccination
Several immunologic parameters were assessed at day 0, day 14, and month 24. At baseline, the no-take group demonstrated higher total IgG responses, IgG1 responses, and neutralization antibody titer. This was not unexpected, given that, on average, the no-take group had been vaccinated more recently than the “take group” (the inverse correlation between total IgG level and time since vaccination was statistically significant).
At day 14, levels of IgG—including IgG1-3 subclasses—and neutralization titers were found to be higher in the take group vs. the no-take group. However, most importantly, at month 24, no difference existed in total IgG, IgG subclass, or neutralizing antibody levels between the 2 groups. Moreover, cellular interferon-gamma secretion was higher in the no-take group, and antibody avidity was similar at 23 months. No difference in vaccinia-specific B-cell numbers was found at 24 months.
Assessing Take in Re-vaccines Unnecessary?
This study demonstrates that, in the setting of re-vaccination, it is not necessary to recall those without a take (for either assessment and/or vaccination again), as a successful immunologic reaction is likely, even in the absence of evidence at the vaccination site.
This finding has major implications for mass vaccination campaigns that would occur in the event of a credible threat of smallpox release. Mass vaccination campaigns will involve the rapid mobilization of people, vaccinators, and supplies in a chaotic environment. A sizable proportion of the population has been vaccinated against smallpox in the past and may not demonstrate a vaccine take upon revaccination. Eliminating the need to assess this segment of the population for vaccine take will remove an additional task in a time of crisis and alleviate the burden on what will be already severely stressed medical resources.
Reference
Wiser I, Orr N, Smetana Z, et al. Alternative immunological markers to document successful multiple smallpox revaccinations. Clin Infect Dis 2011. 52:856-861.
And the 2nd is very, very long, so I'm just posting the link:
Immunity from Smallpox Vaccine Persists for Decades - PMC (nih.gov)
vector7
Dot Collector
jward
passin' thru
I posted three or four items yesterday, including one from UK Health security that repeatedly stresses it's found in the gay, and bisexual communities and has notified the care givers (clinics?) and communities to be aware of rashes. Additionally, another report posted yesterday by Helen Branswell speaks to the current assumptions that they are operating from that transmission may be atypical from what was previously known.
Think Spain or Portugal have stated the 23 confirmations they had (at last time I looked, yesterday or before) were all with gay / bisexual / MSM (men who have sex with men) communities.
Canada is also finding the early confirmations within these communities.
Flutrackers.com is a no nonsense website that publishes accurate and up to the minute information, with all conjectures and suppasitions being well founded and logical hypothesis, not just pulled from their nether regions.
There's also talk of it being an attack, and one of the most out of the box combination of the populations they are finding it in, and the presumed gay sexual contact involved in it's (possibly new) method of transmission, was the idea that animal skin condems had been purposely infected. :: shrug ::
Here's one snippet I still have loaded that speaks a bit to the discussion, the others I posted way up thread, yesterday, when this was a domestic cases thread...
Think Spain or Portugal have stated the 23 confirmations they had (at last time I looked, yesterday or before) were all with gay / bisexual / MSM (men who have sex with men) communities.
Canada is also finding the early confirmations within these communities.
Flutrackers.com is a no nonsense website that publishes accurate and up to the minute information, with all conjectures and suppasitions being well founded and logical hypothesis, not just pulled from their nether regions.
There's also talk of it being an attack, and one of the most out of the box combination of the populations they are finding it in, and the presumed gay sexual contact involved in it's (possibly new) method of transmission, was the idea that animal skin condems had been purposely infected. :: shrug ::
Here's one snippet I still have loaded that speaks a bit to the discussion, the others I posted way up thread, yesterday, when this was a domestic cases thread...
jward
passin' thru
Treatment / Monkeypox
Page last reviewed: July 17, 2021
At this time, there are no specific treatments available for monkeypox infection, but monkeypox outbreaks can be controlled.
Smallpox vaccine, cidofovir, ST-246, and vaccinia immune globulin (VIG) can be used to control a monkeypox outbreak. CDC guidance was developed using the best available information about the benefits and risks of smallpox vaccination and drug use for the prevention and management of monkeypox and other orthopoxvirus infections. ...
Cidofovir and Brincidofovir (CMX001)
Data is not available on the effectiveness of Cidofovir and Brincidofovir in treating human cases of monkeypox. However, both have proven activity against poxviruses in in vitro and animal studies. ...
Tecovirimat (ST-246)
Data is not available on the effectiveness of ST-246 in treating human cases of monkeypox.
Studies using a variety of animal species have shown that ST-246 is effective in treating orthopoxvirus-induced disease. Human clinical trials indicated the drug was safe and tolerable with only minor side effects. ...
Vaccinia Immune Globulin (VIG)
Data is not available on the effectiveness of VIG in treatment of monkeypox complications. Use of VIG is administered under an IND and has no proven benefit in the treatment of smallpox complications. It is unknown whether a person with severe monkeypox infection will benefit from treatment with VIG, however, its use may be considered in such instances. ...
https://www.cdc.gov/poxvirus/monkeyp...treatment.html
Page last reviewed: July 17, 2021
At this time, there are no specific treatments available for monkeypox infection, but monkeypox outbreaks can be controlled.
Smallpox vaccine, cidofovir, ST-246, and vaccinia immune globulin (VIG) can be used to control a monkeypox outbreak. CDC guidance was developed using the best available information about the benefits and risks of smallpox vaccination and drug use for the prevention and management of monkeypox and other orthopoxvirus infections. ...
Cidofovir and Brincidofovir (CMX001)
Data is not available on the effectiveness of Cidofovir and Brincidofovir in treating human cases of monkeypox. However, both have proven activity against poxviruses in in vitro and animal studies. ...
Tecovirimat (ST-246)
Data is not available on the effectiveness of ST-246 in treating human cases of monkeypox.
Studies using a variety of animal species have shown that ST-246 is effective in treating orthopoxvirus-induced disease. Human clinical trials indicated the drug was safe and tolerable with only minor side effects. ...
Vaccinia Immune Globulin (VIG)
Data is not available on the effectiveness of VIG in treatment of monkeypox complications. Use of VIG is administered under an IND and has no proven benefit in the treatment of smallpox complications. It is unknown whether a person with severe monkeypox infection will benefit from treatment with VIG, however, its use may be considered in such instances. ...
https://www.cdc.gov/poxvirus/monkeyp...treatment.html
bassaholic
Veteran Member
Watching Fox business news right now. They are reporting covid cases are up 57% over last two weeks.
Also talking about the first case of monkeypox in Mass.
Also talking about the first case of monkeypox in Mass.
Tristan
Has No Life - Lives on TB
danielboon
TB Fanatic
psychgirl
Has No Life - Lives on TB
Yep.
It won’t take much with a pox on the loose.
night driver
ESFP adrift in INTJ sea
Fatality % ranges from 1% to 10% depending on specific infection vectors...
And the RECIPIENT won't have a CLUE until the pustules start to show up and the Infectious Disease guys get to do the analysis.
And the RECIPIENT won't have a CLUE until the pustules start to show up and the Infectious Disease guys get to do the analysis.
JMG91
Veteran Member
Thanks for this, flame! I wanted to order some of this before, but it was always homeopathic and not a straight extract. So, if one is a family of four--two adults, two children--how long would you have to take the extract if treating the disease, and how long would one of the Amish Ways 2 oz bottles last? Trying to figure out how many bottles to order for my family.
flame
Senior Member
that's a good question, I haven't found out how long to dose with that stuff yet, but if you are a family of 4, I would maybe get two bottles? Apparently, the extract keeps for a long time..
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ainitfunny
Saved, to glorify God.
The health authorities absolutely MUST give smallpox vaccinations NOW on a priority basis TO anyone having sex for pay.
Prostitutes of every stripe (and gays who have sex with strangers and multiple partners daily) COULD CAUSE AN EXPONENTIAL INCREASE IN MONKEY POX cases!
One only needs to show them photos of bad monkey pox infections and the scarring that is lifelong to get their consent.
Prostitutes of every stripe (and gays who have sex with strangers and multiple partners daily) COULD CAUSE AN EXPONENTIAL INCREASE IN MONKEY POX cases!
One only needs to show them photos of bad monkey pox infections and the scarring that is lifelong to get their consent.
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Walkin' Away
Senior Member
Hi All,
Just thinking about all this. Have we actually seen pictures of these people?
Again, I am wondering if this could be a type of Kaposi sarcoma? Considering the questionable ingredients that may have been put in the shots and the damage that may be done to innate immunity...I am just wondering if these pts actually may have VAIDS and this is the beginning of some really bad stuff that we are about to witness.
I am just trying to put pieces of this puzzle together...
Take Care Everyone, Remember....they want us dead!
W. A.
Just thinking about all this. Have we actually seen pictures of these people?
Again, I am wondering if this could be a type of Kaposi sarcoma? Considering the questionable ingredients that may have been put in the shots and the damage that may be done to innate immunity...I am just wondering if these pts actually may have VAIDS and this is the beginning of some really bad stuff that we are about to witness.
I am just trying to put pieces of this puzzle together...
Take Care Everyone, Remember....they want us dead!
W. A.
Tigerlily
Senior Member
Do you think their monkeypox vaccine will be more effective than their covid19 vaccine? Who would they have tested the vaccine on during the required trials?
ainitfunny
Saved, to glorify God.
THE SMALLPOX VACCINE WORKS.
No need for an "experimental monkeypox vaccine".
No need for an "experimental monkeypox vaccine".
From an infectious disease website I have followed for many years-
"
communicated by:
ProMED
[Interestingly, the diagnosis of monkeypox as the West African clade was confirmed by PCR in the UK on 6 May 2022 (NCDC: 15 monkeypox cases confirmed in 2022 | TheCable). This is an important finding because the West African clade is less pathogenic than the Central African clade, with little or no mortality. - Mod.TY]
******
[2] Portugal, Spain, UK: update
Date: Wed 18 May 2022 16:19 BST
Source: Daily Mail [abridged, edited]
Monkeypox hits Europe: Now Portugal and Spain detect virus in men
- 1st signs of global outbreak of rare disease as Portugal, UK, Spain, all find cases
- Experts fear disease is spreading in communities for 1st time, going undetected
- US health officials are monitoring 6 Americans who were in contact with case
Monkeypox has now been spotted in Portugal and Spain, in what could be the first global outbreak of the rare disease.
Spain is monitoring 8 men who it believes are infected, with tests being carried out to confirm they have the virus. All of the men are gay or bisexual, according to local media, and most were detected at STI [sexually transmitted infection] clinics in Madrid.
In Portugal, 5 men have also tested positive and at least 15 more cases are being investigated, health officials there said today. These cases are all male and mostly 'young' -- but it is not yet clear how they caught the virus.
Until now, monkeypox cases were confined to travellers and their relatives returning from western and central Africa, where the virus is endemic. But experts now fear it is spreading more widely for the 1st time after 7 Britons were diagnosed in the past fortnight. In the UK, 6 of them appear to have been infected and the majority are not linked, which suggests more cases are going undetected. Health chiefs are scrambling to find the source of the cases.
Of the British patients, 4 are gay or bisexual men, and officials say the pattern of transmission is 'highly suggestive of spread in sexual networks'.
Regions across Spain have been put on alert following the announcement of 8 suspected cases in Madrid. Confirmation is still awaited from the National Centre for Microbiology but health chiefs say 'great care must be taken.' The country's top public health doctor, Fernando Simón, said 'it is not likely that monkeypox will generate a significant transmission but it cannot be ruled out'. The Spanish health alert system has called on communities to notify public health services 'urgently' of patients with symptoms. He said it was now necessary to take extreme surveillance measures and investigate all the hypotheses about the routes of contagion.
Meanwhile, the suspected cases in Portugal were all detected in the Lisbon and Tagus Valley region. The men are said to be 'stable' and all suffering from 'ulcerative lesions', one of the tell-tale signs of the virus. Portugal's health ministry has issued a warning urging people with lesions and rashes to see a doctor. When these symptoms appear, 'direct physical contact' should be avoided, officials added.
Until now monkeypox had only ever been detected in 4 countries outside of Africa -- the UK, US, Israel, and Singapore. All of the cases had travel links back to Nigeria and Ghana. Infections are more common in central and western Africa, where they can result from direct contact with infected animals.
An expert from the UK Health Security Agency said the latest UK cases 'appear to have acquired the infection via sexual contact'. Dr Mateo Prochazka, who leads the UKHSA team which is investigating monkeypox, described this route of transmission as 'novel'. In England, 7 people have been diagnosed with the virus over the past 2 weeks, 5 of which are in London. Of these, 4 are gay or bisexual men, and only one has recent travel links to a country where the virus is endemic, which is 'highly suggestive' of spread in 'sexual networks', Dr Prochazka added.
Writing on Twitter, he said: '... the high proportion of cases in the current outbreak in England that are gay or bisexual (4/7, 57%) is highly suggestive of spread in sexual networks. This is further suggested by the fact that common contacts have been identified for only 2 of the 4 latest cases.' Other experts said further research is necessary before it will be possible to conclude if the virus is sexually transmissible.
Monkeypox can kill up to one in 10 people who get it but the new cases have the West African variant, which is deadly for around one in 100. Initial symptoms include fever, headache, muscle aches, backache, swollen lymph nodes, chills, and exhaustion. A rash can develop, often beginning on the face, then spreading to other parts of the body including the genitals. The rash changes and goes through different stages, and can look like chickenpox or syphilis, before finally forming a scab, which later falls off.
UK Health Security Agency (UKHSA) bosses have now written to regional NHS teams telling them to stock up on PPE and be on alert for patients with a new rash.
UK health chiefs say the risk to the UK population is low. But they have urged gay, bisexual, and other men who have sex with men to be extra vigilant because they appear to be at higher risk of catching it. These groups have been urged to look out for any unusual rashes or lesions on any part of their body, especially their genitalia, and to contact a sexual health service without delay if they have concerns.
Most scientists believe the outbreak will be small and transmission nothing like the levels seen with COVID. This is because monkeypox is poor at spreading between humans and relies on very close and prolonged contact between people.
[byline: Connor Boyd, Rita Sobot]
--
communicated by:
ProMED from HealthMap Alerts
[The monkeypox (MPX) outbreaks in Spain, Portugal, and the UK are highly unusual. Most of the infected individuals had not traveled to MPX virus endemic countries so their infections must have been acquired locally. Although cases of person-to-person transmission have been reported, particularly among healthcare workers attending MPX cases, chains of transmission occurring simultaneously in 3 different locations is novel. Sexual transmission has not been suspected before. As the reports above indicate, transmission through sexual intercourse has not been proven in these cases and other behaviors involving close physical contact may have been involved. It will be interesting to learn if additional cases are confirmed in any of the 3 countries in the coming days. - Mod.TY "
Home - ProMED - ProMED-mail
ProMED is the largest publicly-available surveillance system conducting global reporting of infectious diseases outbreaks. Subscribe today.
This is echoing and rhyming with the info that "came out" about AIDs back in the later 1980s and 1990s.....
psychgirl
Has No Life - Lives on TB
Very
ainitfunny
Saved, to glorify God.
It sounds the same BECAUSE PEOPLE WHO HAVE SEX WITH EVERYBODY AND THEIR BROTHER are especially vulnerable to certain diseases!
Tigerlily
Senior Member
But, there is an experimental monkeypox vaccine they are planning on using.
Treatment Information for Healthcare Professionals | Mpox | Poxvirus | CDC
Clinician Treatment. Mpox (monkeypox) is a viral disease that occurs mostly in central and western Africa. It was first identified in laboratory monkeys. However, it is much more common among animals such as rats, mice, rabbits, and the African Squirrel.
www.cdc.gov
At this time, there are no specific treatments available for monkeypox infection, but monkeypox outbreaks can be controlled.
Smallpox vaccine, cidofovir, ST-246, and vaccinia immune globulin (VIG) can be used to control a monkeypox outbreak. CDC guidance was developed using the best available information about the benefits and risks of smallpox vaccination and drug use for the prevention and management of monkeypox and other orthopoxvirus infections.
Monkeypox and Smallpox Vaccine
One vaccine, JYNNEOSTM (also known as Imvamune or Imvanex), has been licensed in the United States to prevent monkeypox and smallpox. Because monkeypox virus is closely related to the virus that causes smallpox, smallpox vaccine can also protect people from getting monkeypox. Past data from Africa suggests that smallpox vaccine is at least 85% effective in preventing monkeypox. The effectiveness of JYNNEOSTM against monkeypox was concluded from a clinical study on the immunogenicity of JYNNEOS and efficacy data from animal studies. Experts also believe that vaccination after a monkeypox exposure may help prevent the disease or make it less severe.
ACAM2000, which contains a live vaccinia virus, is licensed for immunization in people who are at least 18 years old and at high risk for smallpox infection. It can be used in people exposed to monkeypox if used under an expanded access investigational new drug protocol.
Smallpox vaccine is not currently available to the general public. In the event of another outbreak of monkeypox in the U.S., CDC will establish guidelines explaining who should be vaccinated. For more information about the smallpox vaccine please visit CDC’s Smallpox Vaccination Information for Health Professionals.
Smallpox vaccination kit.
Cidofovir and Brincidofovir (CMX001)
Data is not available on the effectiveness of Cidofovir and Brincidofovir in treating human cases of monkeypox. However, both have proven activity against poxviruses in in vitro and animal studies.
It is unknown whether or not a person with severe monkeypox infection will benefit from treatment with either antiviral, although their use may be considered in such instances. Brincidofovir may have an improved safety profile over Cidofovir. Serious renal toxicity or other adverse events have not been observed during treatment of cytomegalovirus infections with Brincidofovir as compared to treatment using Cidofovir.
Tecovirimat (ST-246)
Data is not available on the effectiveness of ST-246 in treating human cases of monkeypox.
Studies using a variety of animal species have shown that ST-246 is effective in treating orthopoxvirus-induced disease. Human clinical trials indicated the drug was safe and tolerable with only minor side effects.
Although currently stockpiled by the Strategic National Stockpile, use of ST-246 is administered under an IND.
Vaccinia Immune Globulin (VIG)
Data is not available on the effectiveness of VIG in treatment of monkeypox complications. Use of VIG is administered under an IND and has no proven benefit in the treatment of smallpox complications. It is unknown whether a person with severe monkeypox infection will benefit from treatment with VIG, however, its use may be considered in such instances.
VIG can be considered for prophylactic use in an exposed person with severe immunodeficiency in T-cell function for which smallpox vaccination following exposure to monkeypox is contraindicated.
Melodi
Disaster Cat
Yep, it sure is ...and they can test for Monkey Pox and Small Pox pretty easily, Karpasi Sarcoma is a Cancer, the Poxes are caused by a virus.
Capt. Eddie
Veteran Member
Any bets that you'll be REQUIRED to have the covid "vaccine" to be eligible to get the pox vaccine. "We can't be wasting resources on you pure bloods right?"
ainitfunny
Saved, to glorify God.
I ABSOLUTELY WOULD NOT TAKE the new vaccine AND ADVISE, AGAINST ANYONE TAKING THE NEW Monkeypox VACCINE,
We learned with Covid about the deadly side effects of new experimental vaccines!
We learned with Covid about the deadly side effects of new experimental vaccines!
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Melodi
Disaster Cat
That may be true, but it is also true of anyone who has a blood transfusion or receives a blood product made from the blood of anyone affected by HIV. It was also spread all over Africa both by sex (mostly heterosexual) and the use of repeated use of the same needles by VACCINATION programs often run by missionary organizations. They were not evil, that was standard practice at the time.
It wasn't realized until much later that vaccinations are given to try to prevent or treat killer diseases like Malaria or Sleeping stickers were also infecting thousand of children and adults with HIV.
And that was partly because almost the entire focus of the Western Medical world, especially in the US was on HIV being considered a "Gay" Disease. One that the administration in Washington wouldn't even allow to be named in public!
That is the danger of consider a disease "only" associated with sexual transmission or a marginalized group, especially one that a lot of people don't want to be associated with. That danger is that other issues and means of transmission other than sex will be ingored or not discovered until it is way-way too late.
marsh
On TB every waking moment
33:11 min
U.S. Orders MILLIONS Of Smallpox Vaccines Amid Global Monkeypox Outbreak, Experts Say Remain Calm
Tim Pool
U.S. Orders MILLIONS Of Smallpox Vaccines Amid Global Monkeypox Outbreak, Experts Say Remain Calm. So far seven different countries are reporting confirmed or potential monkeypox cases. Monkeypox is very similar to smallpox and with the US having ordered so many vaccines many are wondering if the government knows something they aren't sharing. Currently doctors and experts say there is nothing to worry about but still many believe in theories about Bill Gates due to his having warned about smallpox just a few months ago
ainitfunny
Saved, to glorify God.
you are not gonna catch ALL sources of infection but where it is most likely to spread to greater numbers of people you have to prioritize!
ainitfunny
Saved, to glorify God.
link?
ainitfunny
Saved, to glorify God.
It has HORRIFYING SCARRING on your face and body as an after effect.
THAT OFFSETS the " only kills 1%!
edited to add:
i just learned if you're pregnant you will probably have a still birth, and if the pox occurs in your eyes you will probably go blind.
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