CORONA Main Coronavirus thread

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Coronavirus has ‘stabilized’ in Florida, Gov. Ron DeSantis says

by: Mahsa Saeidi
Posted: Jul 6, 2020 / 07:21 PM EDT / Updated: Jul 6, 2020 / 07:33 PM EDT

TAMPA, Fla. (WFLA) — Gov. Ron DeSantis said Monday he believes coronavirus has “stabilized” in Florida. The message came during a Florida coronavirus update after this weekend’s grave milestone of the state recording more than 200,000 total cases since the beginning of the pandemic.

The news conference was held at UF Health The Villages hospital in The Villages. Gov. DeSantis spoke with health officials from the hospital, highlighting various hospital capacities throughout the state.

During the news conference, the governor said he believes the virus has now stabilized in the Sunshine State.

“I want us to be in May. I want us to be in early June, where we were at 3, 4 percent (positivity,)” said Gov. DeSantis. “We want to get back to that for sure. I think we’ve stabilized at where we’re at.”

Right now, the governor is resisting calls to issue a statewide mask order. Instead, he’s said he’s trusting Floridians to be responsible and make good decisions.

“There’s no doubt the mask protects you and protects others,” Dr. Anthony Fauci, the nation’s top infectious disease doctor, said last week during a Senate hearing.
Where are masks mandated in Tampa Bay?

As the COVID-19 surge shifts to the west and south, leaders on both sides of the aisle implore Americans to wear masks.

In Texas, it’s now a requirement for all counties with more than 20 cases.

But in Florida, there’s still no statewide requirement for masks.

In three of the past five days, the Sunshine State saw more than 10,000 new daily coronavirus cases. The percentage of people testing positive has also dramatically gone up.

Some public health experts believe we may be the next epicenter of this virus.
Gov. DeSantis says younger people drive COVID-19 surge

“There’s no need to be fearful, let’s just focus on the facts,” said Gov. DeSantis.

The governor says the fact is Florida’s new average coronavirus patient is much younger, and less at risk of dying.

“Now we’ve also said now since May that if you can’t social distance, wearing a facial covering can cut down on the transmission, we believe, some,” said Gov. DeSantis. “But it’s not in lieu of social distancing.”

While wearing a mask is not required statewide, some cities and counties have mandated face coverings as cases continue to go up.

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Heliobas Disciple

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Is it safe for Disney World to reopen this weekend as coronavirus cases soar in Florida?
Curtis Tate
Published 6:54 p.m. ET July 6, 2020

As Walt Disney World prepares to reopen on Saturday, Florida has recorded the largest weekly increase in coronavirus cases in the country.

In just the past seven days, according to the Centers for Disease Control and Prevention, the state has added nearly 67,000 cases. With more than 206,000 cases statewide, according to the Florida Department of Health, the Sunshine State is a coronavirus hot spot.

Orlando, which is about 30 minutes northeast of Disney World, has the second-highest number of coronavirus cases in Florida behind Miami. On Monday, Miami began rolling back its reopening, as Mayor Carlos A. Gimenez halted dine-in services at restaurants and closing gyms, party venues and short-term rentals.

Disney has delayed the July 17 reopening of Disneyland in California, in part because that state, too, has seen a surge in coronavirus cases.

For Disney World, though, the reopening remains on schedule for this weekend.

Gov. Ron DeSantis on Monday dismissed concerns about reopening the theme park.

"I have no doubt it’s going to be a safe environment," he said in a news conference.
Disney World's Magic Kingdom is still planning to reopen Saturday, July 11.

The union that represents hundreds of stage actors who work at Disney World isn't as confident.

"I can’t imagine that anyone thinks it’s wise to reopen a theme park this week," Kate Shindle, president of the Actors Equity Association, told USA TODAY.

Joseph Khabbaza, a pulmonary and critical care specialist at the Cleveland Clinic, said the park should be safe for visitors if people keep their distance from others, wash their hands and use hand sanitizer, don't touch their faces often and wear a face mask.

That, he added, would depend on compliance and enforcement.

"The spreading is really occurring where people are standing shoulder to shoulder," Khabbaza said. "Things can be enforced on a resort."

He said Florida's coronavirus surge has been driven by younger people who have crowded restaurants, bars and beaches as the state has reopened (though it has since banned alcohol consumption in bars again).

"Disney, I think, is in a very different position," he said, noting that it will be their house, and therefore their rules.

A Disney spokesman didn't immediately respond to a request for comment.

Disney World announced in late May that it would be reopening its Magic Kingdom and Animal Kingdom on July 11, followed by Epcot and Disney Hollywood Studios on July 15.

The jump in coronavirus cases have all come in the weeks since Disney made its announcement.

At the same time Disney World is reopening to the public, it is also hosting the National Basketball Association and Major League Soccer as both sportleagues set to get their seasons back on track.

Last week, the NBA said 25 of its players and 10 of its employees have tested positive for the coronavirus. Several MLS players have also tested positive.

The league's best player, Carlos Vela of Los Angeles Football Club, announced on Twitter Monday that he would not travel to Orlando for any games.

"It is in the best interest of the health of my family to stay home and be with my wife during what is a risky pregnancy," Vela tweeted. "I will miss being with my teammates and coaches, but I will be cheering and supporting LAFC from a distance."

Disney is taking precautions at the park, requiring temperature checks and face masks for visitors over the age of two and employees. A squad of cast members will enforce social distancing and the mask requirement. Disney has canceled fireworks, parades, meet-and-greets and other activities that would encourage large group gatherings. The park will operate below capacity, though Disney has not provided specific numbers or percentages. (When the company reopened its first part in Shanghai, China in May, CEO Bob Chapek said it would limit visitors to under 30% of capacity, or 24,000.)

Still, the Actors Equity Association wants Disney to test the stage actors it represents.

"We are still advocating aggressively for our members to have testing as a part of their return to work," Shindle said.

Shindle cited the death of Broadway actor Nick Cordero on Sunday as an example of the devastating impact of the virus. Cordero, 41, had been hospitalized since March, had one leg amputated because of blood clots and battled infection in both lungs.

Those who survive the coronavirus can be left with permanent lung damage.

"This is not a disease to be taken lightly," Shindle said. "It can have a long-term effect on making your living as a performer, even if you are lucky enough to survive."

Khabbaza, who treats coronavirus patients, said anyone on Disney property, whether actors, athletes or visitors, should be fine as long as they follow the guidelines and Disney enforces them.

"All it takes is one Disney-centered outbreak or cluster to start before they have to shut down," he warned.

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Texas coronavirus cases cross 200,000 mark
By Nicole Cobler
Posted at 4:42 PM Updated at 6:24 PM

Texas reached 200,000 total COVID-19 cases Monday, just 17 days after crossing the 100,000 threshold, a figure that took the state nearly four months to hit.

The grim milestone came as the state has reported weeks of surging hospitalizations and new cases, and as Gov. Greg Abbott aimed to clamp down on those rising numbers with a statewide mask order.

Although the number of newly reported cases rose at a slower rate Sunday and Monday, with the Texas Department of State Health Services reporting 5,318 cases Monday, a spokesman for the health agency said the state may see a “big increase” in new cases this week as more local jurisdictions report data after the holiday weekend.

“There were a lot of jurisdictions that didn’t report new cases with the holiday weekend, particularly on Saturday, which would have showed up in yesterday’s update,” agency spokesman Chris Van Deusen said in an email.

The number of cases and hospitalizations has accelerated since Memorial Day, prompting Abbott to close bars, reduce restaurant occupancy, pause additional reopenings and issue a statewide order to wear a face covering in counties with more than 20 COVID-19 cases.

But Texas has yet to see whether the latest restrictions will improve the numbers. The incubation period for the virus is between one and 14 days, meaning data won’t immediately reflect the changes.

In addition to 200,557 confirmed infections to date, state health officials Monday reported 8,698 COVID-19 hospitalizations, a record high for the eighth consecutive day.

The rolling seven-day average of positive tests was 13.5%, according to the health agency. Abbott has said anything above 10% is cause for concern and action to reduce exposure to the virus.

Statewide testing also soared over the weekend. The seven-day average of daily new tests hovered around 50,000 on Friday, Saturday and Sunday.

Hot spots across Texas

As the state’s most populous counties gained national attention over rising cases and reports of crowded hospitals, some local officials and health experts feared that the latest restrictions in Texas might not slow the coronavirus spread.

On Sunday, Austin Mayor Steve Adler told the American-Statesman that the Austin-area’s intensive care units could be overrun in the next 10 to 14 days if hospitalizations continue increasing at their current pace. Officials in San Antonio, Houston and Dallas issued similar warnings.

In the Rio Grande Valley and South Texas, area hospitals have continued to see an alarming increase in the number of hospitalizations and declining availability of ICU beds.

Dr. Jose Vazquez, the Starr County health authority, said COVID-19 deaths in the area have been undercounted and hospital beds are full, The Monitor reported Friday. Vazquez told the newspaper that some patients had to be transferred by helicopter to other areas of the state with available beds.

The Texas Department of State Health Services on Monday reported 43 available ICU beds for the trauma service area that includes Starr and three other counties.

In one South Texas area that covers Victoria, Goliad and four other counties, state health officials reported just nine available ICU beds.

There are nearly 13,000 hospital beds available statewide, 5,300 ventilators and 1,226 ICU beds, according to the health agency.

The agency reported 18 new deaths Monday, bringing the statewide virus death toll to 2,655. It’s a nearly 74% increase since Memorial Day, when officials reported a total of 1,527 coronavirus-related deaths.

The state’s current seven-day average of COVID-19 deaths per day is 36, compared with 27 on Memorial Day.

COVID-19 polling

Meanwhile, statewide polling released Monday found that while most Texans believe controlling the spread of COVID-19 is more important than reopening the economy, they are less concerned about the virus than in April.

And the poll from the University of Texas’ Texas Politics Project found that Abbott’s favorability in Texas has fallen since April.

The poll, which surveyed 1,200 registered voters from June 19 to 29, had a margin of error of plus or minus 2.83 percentage points.

While 52% of Texas voters approved of how Abbott has handled the economy, 49% approved of how he’s handled the state’s response to COVID-19, down from 56% in April.

The poll also found that a majority of Texans, or 53%, said controlling the spread of COVID-19 is more important than helping the economy.

Even so, concern about the coronavirus decreased as new cases and hospitalizations spiked in June.

The number of Texans who reported being “extremely” or “very” concerned about the spread of the virus in their community dropped from 54% in April to 47% in June, according to the Texas Politics Project.

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Arizona COVID-19 cases surpass 100,000 as weekslong spikes continue
Alison Steinbach
Published 9:39 a.m. MT July 6, 2020 | Updated 1:21 p.m. MT July 6, 2020

Known cases of COVID-19 in Arizona passed 100,000 on Monday, just over five months since the first case was identified in Maricopa County in late January and just over two weeks since the case count passed 50,000.

Identified cases rose to 101,441 and known deaths total 1,810, according to the daily report by the Arizona Department of Health Services. The state does not report the number of recovered cases, though it does report hospital discharges.

Rapid case increases and hospitalizations have made Arizona now among the worst hot spots in the nation for COVID-19. The disease is widespread here, and health officials caution people to stay home unless necessary to leave and to wear masks in public.

There is widespread transmission of #COVID19 with the nat'l no. of cases approaching 3 million & AZ surpassing 100,000 cases. Arizonans are safer at home, prevent the spread of this disease by washing your hands & wearing a mask #SaferAtHome#MaskUpArizonahttps://t.co/juqDQLNU5bpic.twitter.com/3MbPlPlYTp
— AZ Dept of Health (@AZDHS) July 6, 2020

Vice President Mike Pence, who visited Arizona on Wednesday, said he is deploying hundreds of medical personnel to assist the state.

Hospitalizations in inpatient and ICU beds and ventilators in use by COVID-19 patients rose on Sunday to their highest reported levels since hospital data reporting began in early April. As of Sunday, a record 3,212 inpatient hospital beds were occupied by suspected and confirmed COVID-19 patients, in addition to a record 839 ICU beds filled across the state.

Monday's dashboard shows 84% of current inpatient beds and 89% of ICU beds were in use, which includes people being treated for COVID-19 and other patients.

Most people who get the disease are not hospitalized.

As a public service, The Arizona Republic is offering coronavirus coverage relating to public safety free of charge. Support The Republic by subscribing to azcentral.com.
The path to 100,000 known cases

Arizona reported its first known case of COVID-19 on Jan. 26 — a member of the Arizona State University community who had traveled to Wuhan, China. At that point, he was the fifth confirmed case in the U.S.

From there, Arizona's case count increased, albeit relatively slowly compared to spikes seen in other parts of the country. By the end of March, there were more than 1,000 known cases in the state.

Starting in late May, after Gov. Doug Ducey's stay-at-home order expired, cases began ballooning and have been spiking daily since.

Arizona's total case count passed 50,000 on June 21 and doubled to more than 100,000 in two weeks.

Here are some of the major case milestones by date reported:

First case: Jan. 26
100 cases: March 21
1,000 cases: March 30
10,000 cases: May 8
25,000 cases: June 6
50,000 cases: June 21
75,000 cases: June 30
100,000 cases: July 6

These are not all the COVID-19 cases in the state. Many new coronavirus cases are believed to be asymptomatic, meaning people can spread the virus without knowing they have it. Those people are less likely to be tested and make it into the official count. Many others may have been unable to get tested due to test shortages early on or are still waiting for their results.

Arizonans have recently reported delays in getting tested and waits of as long as three weeks to get results. The daily cases reported are not all from the previous day's results — they could have been tests conducted weeks ago.

While increased testing over the past month has contributed to an increase in known cases, it is only one factor resulting in the big increase in case numbers. The percentage of tests coming back positive has spiked sharply since mid-May, indicating a significant increase in community spread.

During the past three weeks, cases increased by 176% and tests increased by just 79%. Last week, 22% of tests conducted came back positive.

Here's what you need to know about Monday's new numbers.

Reported cases in Arizona: 101,441

  • Cases increased by 3,352, or 3.4%, from Sunday's 98,089 identified cases since the outbreak began.
  • County cases: 64,915 in Maricopa, 9,873 in Pima, 7,431 in Yuma, 4,600 in Pinal, 3,904 in Navajo, 2,441 in Apache, 2,190 in Coconino, 2,002 in Santa Cruz, 1,413 in Mohave, 948 in Yavapai, 826 in Cochise, 371 in La Paz, 349 in Gila, 152 in Graham and 26 in Greenlee, according to state numbers.
  • The rate of cases per 100,000 people is highest in Santa Cruz County, followed by Navajo, Apache and Yuma counties.
  • The Navajo Nation reported 7,840 cases and 378 confirmed deaths as of Sunday. The Navajo Nation includes parts of Arizona, New Mexico and Utah.
  • The Arizona Department of Corrections said 457 inmates had tested positive for COVID-19 as of Thursday; 3,819 inmates have been tested out of a population of more than 40,000. Four incarcerated people have been confirmed to have died of COVID-19, with eight additional deaths under investigation.
  • While race/ethnicity is unknown for 51% of cases, 23% of cases are Hispanic or Latino, 15% of cases are white, 7% are Native American and 2% are Black.
  • Laboratories have completed 617,343 diagnostic tests for COVID-19, 13.4% of which have come back positive. The percent of positive tests has increased in the past month. It was 22% last week.

Reported deaths: 1,810 known deaths

On Monday, one new death was reported.

County deaths: 881 in Maricopa, 282 in Pima, 133 in Navajo, 98 in Yuma, 96 in Coconino, 92 in Apache, 88 in Mohave, 78 in Pinal, 24 in Santa Cruz, 14 in Cochise, 10 in Yavapai, six in Gila, five in La Paz and fewer than three in Graham and Greenlee.

People aged 65 and older made up 1,322 of the 1,810 deaths, or 73%.

While race/ethnicity is unknown for 14% of deaths, 42% of those who died were white, 22% were Hispanic or Latino, 17% were Native American and 3% were Black.

Hospitalizations hover at high levels

  • Inpatients with suspected and confirmed COVID-19 tallied a record 3,212 statewide on Sunday. Hospitalizations have eclipsed 1,000 daily since June 1 and surpassed 2,000 for the past two weeks.
  • Ventilator use for suspected and confirmed COVID-19 patients was at 533 on Sunday, the highest number so far. Overall, 51% of ventilators remained available Sunday.
  • ICU bed use for suspected and confirmed positive COVID-19 patients was at 839 on Sunday, the highest number so far. The number has been above 500 daily since June 15, with a relatively steady increase in the weeks since.
  • Emergency department visits for patients with suspected or confirmed COVID-19 dropped to 1,306 Sunday. Emergency department visits hit a record 1,847 patients Thursday. Visits surpassed 800 on June 5 and have been above that level every day since. During April and May, emergency department daily visits for COVID-19 were typically in the 400s and 500s, rising into the 600s in the last few days of May.
  • The number of patients with suspected or confirmed positive COVID-19 discharged from hospitals was at 475 on Sunday, continuing high discharge numbers over the past week. This is the highest number of discharges so far.
[...]
 

Heliobas Disciple

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'We'll be living with masks for years': COVID-19 through the eyes of a pandemic expert
Since the summer of 2019, I've been speaking with one of the world's leading pandemic experts about what a global outbreak could look like. Now, as the world enters a grim new phase, he says we're in a whole new ball game.

Claire Reilly
July 6, 2020 11:35 a.m. PT

Eric Toner has been planning for a pandemic for years. He's briefed world leaders on outbreaks and how to best prepare entire nations for mass casualties. He's simulated epidemics in real time and studied the world's response to major global health emergencies like SARS and the 1918 influenza pandemic.

But nothing could've prepared him for how the COVID-19 pandemic would play out.

Toner is a senior scholar at the Johns Hopkins Center for Health Security and a world leader in pandemic preparedness. The threat of a novel coronavirus is not new to him. In fact, in October 2019, Toner and the team at Johns Hopkins ran a coronavirus pandemic simulation in New York, months before COVID-19 started spreading across the world. As part of the half-day, tabletop exercise, Toner met with other health professionals to walk through a theoretical coronavirus outbreak and examine how governments and private businesses would respond.

Johns Hopkins has run these simulations for years, with Hollywood-sounding code names like Dark Winter (smallpox) and Clade X ("a biologically-engineered, intentionally-released airborne pathogen" which caused hundreds of millions of hypothetical deaths). The goal of the simulations is to help public health experts and policymakers better prepare for the eventual day a real pandemic arrives.

Now that day has come.

But simulating a pandemic is a far cry from watching the world handle an actual pandemic unfolding in real time. On that front, Toner says some countries are failing the test.

"The US response has been extraordinarily disappointing and wrongheaded," he told me via Zoom, at the end of June. "Whenever there's been an opportunity to do the right thing, we seem to have done the wrong thing. The US has to recognize that it is competing for first or second position of the worst affected country in the world."

Caught off guard

It's not the first time I've spoken to Toner about pandemics.

We first met in July 2019, when I traveled to the Johns Hopkins Center for Health Security in Baltimore to interview him about how the world would prepare for a pandemic. The interview was for "Hacking the Apocalypse" -- CNET's new documentary series looking at the tech solutions that could save us from doomsday events. Naturally, a series about terrifying global disasters had to include an episode on pandemics, but for me (and the rest of the team working on the series), this all felt theoretical. A kind of thought experiment that might play out in your head while you watch Contagion on TV.

But then came 2020. The world started to enter lockdown and words like "pandemic," "social distancing" and "quarantine" began embedding themselves in the daily vernacular. Our entire documentary series needed to be rewritten and recut. Suddenly, none of this was theoretical. And as I rewatched my original interview with Toner (conducted in a small room! Without face masks!) I kept rewinding the same part to play over and over.

"Is there a chance that we could be caught off guard by some sort of horrible, mutant bat influenza?" I had asked him on that day, five months before cases of the novel coronavirus were first reported.

"Yes," Toner replied. "And we probably will be."

I've spoken to Toner a number of times since then. Back in April, his assessment was grim.

"I think one would have to be clueless not to be scared right now," he told me, over a Zoom call from his home office. "The current coronavirus pandemic is worse than many that we have anticipated in the past ... this is going to end up being a truly historically bad event."

Now, as the world enters the second half of an entire year dominated by the pandemic, the situation is still just as serious.

According to a July 1 update from Johns Hopkins (which has been tracking pandemic stats and providing regular situation reports), the pandemic has hit nearly every country across the world, with more than 10 million reported cases and more than half a million deaths. Of the more than 200 countries and territories reporting cases, 86 are reporting community transmission -- essentially, outbreaks that can't be traced to recent travel, other known cases or known clusters of the disease.

When I speak to Toner at the end of June, our mood has shifted. This is no longer an emerging threat. And unlike our previous conversations, I'm not expecting him to tell me about the quick fix that will end this crisis.

It's clear we're no longer in a sprint. We're in for a marathon.

'There will be no lull'

Many countries have seen success in the fight against the coronavirus, locking down early, moving quickly to adopt the World Health Organization's advice and ramping up diagnostic testing to identify and isolate localized outbreaks as they surfaced.

But as the northern hemisphere entered summer, hopes of flattening the curve in the US soon ran up against reports of cases continuing to rise as states reopened. Toner, though, is quick to talk down any mention of a "second wave."

"When you're underwater, it's really hard to tell how many waves are passing over you," Toner says. "I don't know whether it's a first wave or a second wave. I don't think it makes any difference. There is a resurgence of cases that, in some states, looks like just a continuation of their outbreaks. In other states, it'll look more like a second wave.

"I think what's important is that there's going to be no summertime lull with a big wave in the fall. It's clear that we are having a significant resurgence of cases in the summer, and they'll get bigger. And it'll keep going until we lock things down again."

Unlike the influenza virus, which was behind the 1918 pandemic that claimed as many as 50 million to 100 million lives around the world, Toner says there's no good evidence of seasonality with COVID-19. Until we have a vaccine, any rise or fall in cases will be based on social factors: communities locking down and families sheltering in place. And, as was the case back in 1918, individuals wearing masks.

There is some good news to come out of the first six months of the pandemic. Hospitals are getting better at managing symptoms and intervening before cases reach a point of no return, helping to reduce the death rate. He points to therapies like remdesivir, which has shown positive effects in trials and has been authorized for hospitalized COVID patients, and convalescent plasma therapy, which could be used as a way to transfer a level of immunity to sick patients.

But there's no silver bullet. Experts agree that it will be at least a year from now before we have a vaccine that's accessible to most people. Mass immunization likely won't come until 2022, and even then, Toner says vaccination may require a double dose to be effective.

And until then?

"I think that mask wearing and some degree of social distancing, we will be living with -- hopefully living with happily -- for several years," he says.

For many of us, this long timeline can lead to a feeling of hopelessness. But Toner says there's a way to control our future, and it's not all that different from the advice he's given in simulations, advice that dates back more than a century.

"It's actually pretty straightforward. If we cover our faces, and both you and anyone you're interacting with are wearing a mask, the risk of transmission goes way down. Being outside, having distance between you and other people reduces the risk of transmission dramatically.

"There are a lot of things you can do and maintain those conditions. If you spread out, if you maintain distance, if you avoid crowded places, you could go to a beach, you go to the mountains, you could go to a lake, you can do things outside without a problem."

As for those who refuse to wear a mask, Toner doesn't mince his words.

"They will get over it," he says. "It's just a question of how many people get sick and die before they get over it."

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Heliobas Disciple

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Think a 'mild' case of Covid-19 doesn’t sound so bad? Think again
Adrienne Matei [The Guardian]
July 6, 2020

Conventional wisdom suggests that when a sickness is mild, it’s not too much to worry about. But if you’re taking comfort in World Health Organization reports that over 80% of global Covid-19 cases are mild or asymptomatic, think again. As virologists race to understand the biomechanics of Sars-CoV-2, one thing is becoming increasingly clear: even “mild” cases can be more complicated, dangerous and harder to shake than many first thought.

Throughout the pandemic, a notion has persevered that people who have “mild” cases of Covid-19 and do not require an ICU stay or the use of a ventilator are spared from serious health repercussions. Just last week, Mike Pence, the US vice-president, claimed it’s “a good thing” that nearly half of the new Covid-19 cases surging in 16 states are young Americans, who are at less risk of becoming severely ill than their older counterparts. This kind of rhetoric would lead you to believe that the ordeal of “mildly infected” patients ends within two weeks of becoming ill, at which point they recover and everything goes back to normal.

While that may be the case for some people who get Covid-19, emerging medical research as well as anecdotal evidence from recovery support groups suggest that many survivors of “mild” Covid-19 are not so lucky. They experience lasting side-effects, and doctors are still trying to understand the ramifications.

Some of these side effects can be fatal. According to Dr Christopher Kellner, a professor of neurosurgery at Mount Sinai hospital in New York, “mild” cases of Covid-19 in which the patient was not hospitalized for the virus have been linked to blood clotting and severe strokes in people as young as 30. In May, Keller told Healthline that Mount Sinai had implemented a plan to give anticoagulant drugs to people with Covid-19 to prevent the strokes they were seeing in “younger patients with no or mild symptoms”.

Doctors now know that Covid-19 not only affects the lungs and blood, but kidneys, liver and brain – the latter potentially resulting in chronic fatigue and depression, among other symptoms. Although the virus is not yet old enough for long-term effects on those organs to be well understood, they may manifest regardless of whether a patient ever required hospitalization, hindering their recovery process.

Another troubling phenomenon now coming into focus is that of “long-haul” Covid-19 sufferers – people whose experience of the illness has lasted months. For a Dutch report published earlier this month (an excerpt is translated here) researchers surveyed 1,622 Covid-19 patients with an average age of 53, who reported a number of enduring symptoms, including intense fatigue (88%) persistent shortness of breath (75%) and chest pressure (45%). Ninety-one per cent of the patients weren’t hospitalized, suggesting they suffered these side-effects despite their cases of Covid-19 qualifying as “mild”. While 85% of the surveyed patients considered themselves generally healthy before having Covid-19, only 6% still did so one month or more after getting the virus.

After being diagnosed with Covid-19, 26-year-old Fiona Lowenstein experienced a long, difficult and nonlinear recovery first-hand. Lowenstein became sick on 17 March, and was briefly hospitalized for fever, cough and shortness of breath. Doctors advised she return to the hospital if those symptoms worsened – but something else happened instead. “I experienced this whole slew of new symptoms: sinus pain, sore throat, really severe gastrointestinal issues,” she told me. “I was having diarrhea every time I ate. I lost a lot of weight, which made me weak, a lot of fatigue, headaches, loss of sense of smell …”

By the time she felt mostly better, it was mid-May, although some of her symptoms still routinely re-emerge, she says.

“It’s almost like a blow to your ego to be in your 20s and healthy and active, and get hit with this thing and think you’re going to get better and you’re going to be OK. And then have it really not pan out that way,” says Lowenstein.

Unable to find information about what she was experiencing, and wondering if more people were going through a similarly prolonged recovery, Lowenstein created The Body Politic Slack-channel support group, a forum that now counts more than 5,600 members – most of whom were not hospitalized for their illness, yet have been feeling sick for months after their initial flu-like respiratory symptoms subsided. According to an internal survey within the group, members – the vast majority of whom are under 50 – have experienced symptoms including facial paralysis, seizures, hearing and vision loss, headaches, memory loss, diarrhea, serious weight loss and more.

“To me, and I think most people, the definition of ‘mild’, passed down from the WHO and other authorities, meant any case that didn’t require hospitalization at all, that anyone who wasn’t hospitalized was just going to have a small cold and could take care of it at home,” Hannah Davis, the author of a patient-led survey of Body Politic members, told me. “From my point of view, this has been a really harmful narrative and absolutely has misinformed the public. It both prohibits people from taking relevant information into account when deciding their personal risk levels, and it prevents the long-haulers from getting the help they need.”

At this stage, when medical professionals and the public alike are learning about Covid-19 as the pandemic unfolds, it’s important to keep in mind how little we truly know about this vastly complicated disease – and to listen to the experiences of survivors, especially those whose recoveries have been neither quick nor straightforward.

It may be reassuring to describe the majority of Covid-19 cases as “mild” – but perhaps that term isn’t as accurate as we hoped.

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Melodi

Disaster Cat

Herd immunity ‘unachievable’ after only 5% of population exposed to coronavirus, Spanish study finds
Director of health institute says Spaniards ‘can’t relax’ and must protect each other



People queue up to be tested for coronavirus in Ordizia, Basque Country, Spain, on 6 July, 2020.

People queue up to be tested for coronavirus in Ordizia, Basque Country, Spain, on 6 July, 2020. ( Javi Colmenero/Europa Press via Getty Images )
The Independent employs reporters around the world to bring you truly independent journalism. To support us, please consider a contribution.
A nationwide antibody study in Spain has found that only 5.2 per cent of the country’s population has been exposed to coronavirus, suggesting that herd immunity could be unachievable.
The findings marked the conclusion of a three-month study into the prevalence of the virus, which involved testing almost 70,000 people across Spain three times in as many months.

The results confirmed initial reports in May that a low percentage of people in Spain had developed antibodies after being infected with Covid-19.

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In an article published in the health journal the Lancet on Monday, the scientists behind the study said: ”Despite the high impact of COVID-19 in Spain, prevalence estimates remain low and are clearly insufficient to provide herd immunity.”






”This cannot be achieved without accepting the collateral damage of many deaths in the susceptible population and overburdening of health systems. In this situation, social distance measures and efforts to identify and isolate new cases and their contacts are imperative for future epidemic control,” they added.
The study also discovered that 14 per cent of people who tested positive for antibodies in the first test produced a negative result in the final test, which implies that immunity to Covid-19 can be short-lived. This phenomenon was most common among those who never displayed symptoms.

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As a result, Dr Raquel Yotti, director of the Carlos III Health Institute which co-led the study, said: ”Immunity can be incomplete, it can be transitory, it can last for just a short time and then disappear.”
After appealing to Spaniards to remain careful, she added: ”We can’t relax, we must keep protecting ourselves and protecting others.”

Spain, which has been one of the European countries worst affected by the pandemic, has recorded 28,385 deaths from coronavirus so far. It is still struggling with regions outbreaks, including one that led to the lockdown of more than 200,000 people in Lleida province in the northeast of the country last week.
The Spanish study report came a month after the results of an antibody study in Switzerland involving 2,766 participants were published in the Lancet. It suggested that a low percentage of the population in Geneva tested positive for antibodies, despite the city being a hotspot for the disease.
Additional reporting from Reuters
 

Melodi

Disaster Cat
Meanwhile in the United Kingdom...

Coronavirus: Pubs close again after punters test positive for COVID-19

Three bars are shutting their premises after opening their doors for the first time since lockdown measures were imposed.
Tom Gillespie, news reporter
Tom Gillespie
News reporter @TomGillespie1
Tuesday 7 July 2020 09:07, UK
The Lighthouse, The Fox and Hounds and the Village Home are all closed. Pic: Google Street View

Image:The Lighthouse, The Fox and Hounds and the Village Home are all closed. Pics: Google Street Vie
A number of pubs which reopened for the first time since lockdown measures were imposed have had to close again after punters tested positive for coronavirus.
Bars across England welcomed drinkers on Saturday more than three months after the coronavirus outbreak closed down the hospitality sector.
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But three pubs have since alerted their patrons that they have had to shut again after cases of COVID-19 were detected.
Coronavirus UK tracker: How many cases are in your area – updated daily
Coronavirus UK tracker: How many cases are in your area – updated daily

The Lighthouse Kitchen and Carvery in Burnham-on-Sea, Somerset, said a customer had tested positive.
The pub added it was making its way through a list of people who were in the bar on Saturday and may have come into contact with the customer.

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In a statement posted on Facebook, the pub added: "All our staff are going to be tested and we will reopen when the time is safe to do so."


:: Listen to Sophy Ridge on Sunday on Apple podcasts, Google podcasts, Spotify, Spreaker
More from Covid-19
The Fox and Hounds in Batley, West Yorkshire, said it would be closed until further notice after receiving a call from a customer on Monday to say they had tested positive for coronavirus.
The pub said on Facebook that all its staff had since taken a test and the premises will be "fully deep cleaned and when safe to do so we will reopen our doors".
matt hancock







'I'm pleased with what happened yesterday'
The Village Home pub in Alverstoke, Gosport, said it had also "had a case of coronavirus" on the premises and added that "some of us are in isolation".
The bar said on Facebook: "The pub is now shut but all being well will open again on Saturday. Anyone who was in the pub over the weekend there is no need to isolate unless you show symptoms or are contacted direct by the trace group. Thank you and hope to see you soon."
 

Melodi

Disaster Cat
I can't verify this one as it was posted by a disabled friend on Facebook (she isn't the doctor writing this) but it was so powerful I wanted to pass it on, also in case, someone local can verify the story (or not).

From a Facebook post (I know the poster but am not sharing it here, I do not know the doctor)
Dr Richard Loftus posted this from the front lines. Take a minute and read the whole thing please.

“I'm in a hotspot hospital in a hotspot region (Coachella Valley, Inland Empire, CA). We just converted the entire second floor of our hospital to COVID-19 care yesterday, July 1. We have 65 inpatients with COVID-19 in a hospital with 368 beds. It is the same at our other 2 hospitals in the Valley. We spent yesterday deciding the ethical way to divide up limited remdesivir (30 patients' worth) for the hospital patients. My 20 incoming interns for our IM resident were exposed to COVID 2 weeks ago during their computer chart training; apparently 100% of our computer trainers had COVID19. One intern tested positive 7 days later and I insisted we re-test them all again, as there are almost certainly other cases with minimal symptoms. I raided my household and took my entire supply of face shields to the hospital for the residents to wear on their first day, and I paid $1000 of my own money to equip all of my residents with medical-grade face shields. I require all residents to wear a surgical mask or N95 with face shield if they are within 6 feet of another human, patient or coworker.

Roughly 20% of our inpatients die. Only 30% of our ventilated patients survive. (We try to avoid ventilation at all costs. Some people insist on being full code and decompensate despite high flow with face mask, proning, dexamethasone, antibiotics, and a cocktail of famotidine, zinc, Vitamin D, Vitamin C, NAC, and melatonin--we throw everything we can at each case, so long as it won't hurt them.)

My administrative assistant, who sits adjacent to the interns, just went home with COVID symptoms. Her test is pending.

In the Southwest, we are experiencing catastrophic exponential growth. I have had multiple families--siblings, parent-child, spouses--admitted with COVID-19. I had a 31 year old come in satting 78% on room air; he had been sequestering himself in his bedroom for a week to avoid infecting his elderly parents, with whom he lived. His sister, the only person he saw outside his immediate household in the 10 days prior to onset of fever, cough, and dyspnea, had also had fevers but had tested "negative" at our other large hospital so he thought it was safe to visit her. (Sigh. The Quest PCR test is about 80% sensitive, we think--it had emergency approval, so sensitivity data was not required. The Cepheid rapid COVID PCR test is 98.5% sensitive but is in short supply due to limited reagent availability.)

I'm glad some of you are sheltered from what unbridled COVID-19 looks like. It's a hell show. This is *July*. What do you think my hospital will look like in winter?...

This is real. Doctors in places with proper public health responses will see few cases in their hospitals--like UCSF--but let me tell you something: The laws of physics and biology don't change. If you're in an unaffected region, an introduction and poor governance and low use of physical distancing and masks will give you an exponential increase in no time flat (i.e. 2-4 weeks). That's pandemic math. And 20% of the population infected needs a hospital. You *will* run out of beds with an unbridled pandemic. There is almost ZERO pre-existing immunity to SARS-CoV-2. There may be some "priming" of T-cell responses due to exposure to other "benign" beta-coronaviruses, but we have no idea if that explains the 20-40% of people who seem to get minimal symptoms. Asymptomatic infected persons, however, can, and do, spread COVID to those who die from it.

By the way: I've seen scary looking CT scans of the lungs that look like terrible interstitial pneumonia in a patient who had ZERO symptoms and SaO2 94% on room air. She came in for palpitations and the intern overnight got a chest CT for cardiac reasons. We didn't know it was COVID until her test came back 36 hours later. So "asymptomatic" does NOT mean "no biological activity." The virus replicates furiously in people who feel fine. Kids can spread this as easily as grown ups, even if they feel okay.

Related: I've talked to two previously healthy patients ages 32 and 44 who are 3 and 4 months, respectively, post their acute COVID. They continue to have cough, nightsweats, fever, fatigue. How many survivors have "post-COVID syndrome"? We don't know. Less than 20% but we're not sure. I've asked my hospital to allow me to establish a post-COVID clinic to care for and study survivors. Both NIH and UW are planning similar efforts based on my dialogues with them.

Autopsies show anoxic brain injury in many patients who died of COVID, not to mention microthrombi throughout the lungs and megakaryocytes in massive infiltrations in their hearts and other organs. People get heart failure, lung fibrosis, and permanent kidney injury from COVID-19. This is a disease of the vascular systems, and it can affect any organ, with lungs and kidneys being especially at risk.

In early May, thanks to lockdown, our census of 55 came down to 10 COVID cases, and for a brief moment, I actually had hope that the worst nightmares I had about COVID, as a biohazard virology-trained hospitalist, would not come to pass. Then we re-opened, without test/trace/isolate systems anywhere close to adequate. Eight weeks ago my county decided to make masks "optional," despite 125 doctors begging them not to do that. Now we're worse than we were in April. And it's getting worse every day.

You wanna see if COVID is real? Come walk on my COVID ward with me. It's real. Hearing people talk about it as if it's an exaggeration is, well, rage-inducing, honestly. Denial is the most common reaction to a pandemic. Denial is how the US will wind up with 1.1 million deaths instead of 30,000. I saw AIDS denialists get killed by their belief that HIV "isn't real, it's a pharma conspiracy of the medical industrial complex." Yeah, right, if you say so. I watched patients with those beliefs die.

The hardest part about this is, every new case I treat exposes me. I have assiduous hot zone technique. But no technique is bulletproof. If you keep exposing me to case after case, eventually, the virus will get through my defenses. I'm a 50 year old hypertensive. I don't expect to do well if I get infected. For now, I keep going to work. I'm one of the few pushing forward on COVID clinical trials, basic science, public health messaging, and diagnostic studies at my hospital. I feel a responsibility to keep going. I wake up with nightmares every morning at 4am. But I'm going to keep going for now. I feel very alone a lot of the time. People are not taking this seriously, and it's costing lives. -R

"Everything we do before a pandemic will seem alarmist. Everything we do after a pandemic will seem inadequate. This is the dilemma we face, but it should not stop us from doing what we can to prepare. We need to reach out to everyone with words that inform, but not inflame. We need to encourage everyone to prepare, but not panic." — Michael O. Leavitt, 2007

--
Richard A. Loftus, MD

"Never be afraid to raise your voice for honesty and truth and compassion against injustice and lying and greed. If people all over the world...would do this, it would change the earth." --William Faulkner”
 

Mixin

Veteran Member
"Everything we do before a pandemic will seem alarmist. Everything we do after a pandemic will seem inadequate. This is the dilemma we face, but it should not stop us from doing what we can to prepare. We need to reach out to everyone with words that inform, but not inflame. We need to encourage everyone to prepare, but not panic." — Michael O. Leavitt, 2007

The Bird Flu days were very scary. I suspect most of those who followed that disease grew accustomed to the idea of wearing a mask, not even considering if it would be mandatory or not. Had it hit our shores, I would not have needed the govt to tell me to stay home and wear a mask if I had to go out.
 

lonestar09

Veteran Member

Indian man wears gold face mask to ward off coronavirus
July 4, 2020, 6:46 AM PDT
Businessman Shankar Kurhade wears a facemask made of gold and being worth 289,000 rupees amid concerns over the COVID-19 coronavirus outbreak, in Pune (AFP Photo/Sanket WANKHADE)

Businessman Shankar Kurhade wears a facemask made of gold and being worth 289,000 rupees amid concerns over the COVID-19 coronavirus outbreak, in Pune (AFP Photo/Sanket WANKHADE)
An Indian man said he paid about $4,000 for a bespoke gold face mask to protect him from the coronavirus raging in the country.

The precious metal covering weighs 60 grams (two ounces) and took craftsmen eight days to make, said businessman Shankar Kurhade, from the western city of Pune.

"It is a thin mask and has tiny pores that is helping me to breathe," Shankar told AFP.

"I am not sure if it will be effective to protect me from a coronavirus infection but I am taking other precautions," he added.

When going out, the 49-year-old said he likes to adorn himself with gold jewellery weighing a kilogramme, including a bracelet, necklace and rings on each finger of his right hand.

Kurhade -- whose company makes industrial sheds -- said he got the idea for the gold face mask after seeing a media report about a man wearing one made from silver.

"People are asking me for selfies," he said.

"They are awestruck when they see me wearing the gold mask in markets."

India has made face masks mandatory in public places in a bid to control the spread of the virus in the country, which has around 650,000 confirmed cases and more than 18,600 fatalities.
 

Melodi

Disaster Cat
This is what could have happened to that poor young woman working in McDonald's the creep left in a cast after he beat her up because her boss told her not to serve someone in a car (at the drive-through) without a mask. This busdriver's fate has rocked France and Europe - no matter what people think of wearing masks - beating up employees is stupid, wrong and I hope the perps are jailed for life.

Pictured: Bus driver father-of-three left brain dead after he was beaten up by gang who refused to wear face masks – as his wife says: 'I'm living a nightmare'
  • Philippe Monguillot, 58, was attacked by a gang of fare-dodgers in Bayonne
  • His wife Veronique said the couple's lives were 'destroyed in a matter of seconds'
  • The five attackers described as 'down-and-out' drug users are facing charges
By PETER ALLEN FOR MAILONLINE

PUBLISHED: 09:01, 7 July 2020 | UPDATED: 09:03, 7 July 2020

The French bus driver left brain-dead after an attack by passengers who refused to wear face masks has been named as 58-year-old Philippe Monguillot - as his wife said she was 'living in a nightmare'.
Mr Monguillot, a father of three, was dragged from the driver's seat and savagely beaten by the gang of fare-dodgers as he tried to enforce coronavirus rules on the bus in Bayonne.
The gang of five, described by prosecutors as 'down-and-out' drug users, are facing criminal charges but have not yet been publicly identified.
The driver's wife Veronique Monguillot, 52, told Le Parisien that the couple's lives 'were destroyed in a couple of seconds'.
Bus driver Philippe Monguillot, pictured with his wife Veronique, was dragged from the driver's seat and savagely beaten by a gang of fare-dodgers as he tried to enforce coronavirus rules


+2
Bus driver Philippe Monguillot, pictured with his wife Veronique, was dragged from the driver's seat and savagely beaten by a gang of fare-dodgers as he tried to enforce coronavirus rules
Mrs Monguillot said: 'He can't leave us like this, he was going to be 59 years old soon. No, you don't do this over a bus ticket. You don't kill for free like this!'
The Monguillots are the parents of three daughters aged 18, 21 and 24, and they are being supported by friends and colleagues who have set up a support group.
'Philippe was going to retire in a year and we thought we were going to buy a motorhome in September,' said Mrs Monguillot, who added: 'I don't want to face the facts... I feel like I'm living a nightmare.'
Mrs Monguillot said the gang of five were known to her husband, having had an argument about unpaid fares earlier in the day.
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A prosecuting source has described them as 'down and outs who were well known for sitting around the town with dogs, drinking and taking drugs.'
Mr Monguillot was dragged out of his bus by them, and then savagely punched and kicked, to the extent that his head was disfigured.
Masks are currently compulsory on all public transport in France, but members of the group refused to put them on when they got on the vehicle – a cross between a bus and a tram run by the Chronoplus company – at about 7pm on Sunday.
Describing the attack on Mr Monguillot, an investigating source said: 'They got on the bus without masks, and also refused to show a ticket.
'The first to get on had a dog with him – they just assumed they could all get on and do what they want, but the driver had to do his job.
The gang of five got on the bus in Bayonne (shown on a map in south-western France) without wearing a masks and refused to show a ticket, it is alleged


+2
The gang of five got on the bus in Bayonne (shown on a map in south-western France) without wearing a masks and refused to show a ticket, it is alleged
'When he stood up to them, a very unpleasant argument developed, and voices were raised and then the driver was attacked when everybody spilled out on to the bus platform.
'Philippe was punched and kicked repeatedly and then left with serious injuries, before the gang escaped.'
A colleague of Mr Monguillot described him as a 'decent and hardworking man who always looked after passengers.'
He added: 'There has been a lot of tension over masks, because they are the law, but bus staff are not police, and we should not have to enforce the law.'
The Chronoplus colleague said there had been three other assaults related to masks in recent days, but none as serious as the one involving Mr Monguillot.
Claude Olive, the Mayor of Bayonne, said meetings were in progress to try and improve security on buses.
'This was a barbaric attack,' said Mr Olive. 'Philippe was a wonderful person who should have been protected.'
Masks became mandatory as France began to move out of Covid-19 lockdown towards the end of May.
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Pictured: Bus driver left brain dead after being punched in mask row
 

Zagdid

Veteran Member

Brazil’s President Bolsonaro tests positive for COVID-19
By MARCELO DE SOUSA and DAVID BILLER41 minutes ago

RIO DE JANEIRO (AP) — Brazil’s President Jair Bolsonaro said Tuesday he has tested positive for COVID-19 after months of downplaying the coronavirus’s severity while deaths mounted rapidly inside the country.

The 65-year-old populist who has been known to mingle in crowds without covering his face confirmed the results while wearing a mask and speaking to reporters huddled close in front of him in the capital, Brasilia. He said he is taking hydroxychloroquine, the anti-malaria drug that has not been proven effective against COVID-19.

“I’m, well, normal. I even want to take a walk around here, but I can’t due to medical recommendations,” Bolsonaro said. “I thought I had it before, given my very dynamic activity. I’m president and on the combat lines. I like to be in the middle of the people.”

Brazil, the world’s sixth-biggest nation, with more than 210 million people, is one of the outbreak’s most lethal hot spots. More than 65,000 Brazilians have died from COVID-19, and over 1.5 million have been infected.

Both numbers are the world’s second-highest totals, behind those of the U.S., though the true figures are believed to be higher because of a lack of widespread testing.

Bolsonaro has often appeared in public to shake hands with supporters and mingle with crowds, at times without a mask. He has said that his history as an athlete would protect him from the virus and that it would be nothing more than a “little flu” if he were to contract it.

He has also repeatedly said that there is no way to prevent 70% of the population falling ill with COVID-19 and that local authorities’ efforts to shut down economic activity would ultimately cause more hardship than allowing the virus to run its course.

Bolsonaro repeated those sentiments Tuesday, likening the virus to a rain that will fall on most people and saying that some, like older people, must take greater care.

“You can’t just talk about the consequences of the virus that you have to worry about. Life goes on. Brazil needs to produce. You need to get the economy in gear,″ he said.

Cities and states last month began lifting restrictions that had been imposed to control the spread of the virus, as deaths began to decline along with the occupancy rate in intensive care units.

The World Health Organization’s emergencies chief, Dr. Michael Ryan, wished Bolsonaro a speedy recovery and said his infection “brings home the reality of this virus” by showing that it doesn’t distinguish between “prince or pauper.”

The president told reporters he underwent an X-ray of his lungs on Monday after experiencing fever, muscle aches and malaise. As of Tuesday, his fever had subsided, he said, and attributed the improvement to hydroxychloroquine, which he, like President Donald Trump, has long promoted.

He stepped back from the journalists and removed his mask at one point to show that he looks well.

Bolsonaro has repeatedly visited the hospital since taking office, requiring several operations to repair his intestines after he was stabbed on the campaign trail in 2018.

He said he canceled a trip this week to the country’s northeast region and will continue working via videoconference and receive rare visitors when he needs to sign a document.

Over the weekend, the Brazilian leader celebrated American Independence Day with the U.S. ambassador to Brazil, then shared pictures on social media showing him in close quarters with the diplomat, several ministers and aides. None wore masks.

The U.S. Embassy said on Twitter that Ambassador Todd Chapman is not showing any COVID-19 symptoms but would be tested.

Bolsonaro tested negative three times in March after meeting with the Trump in Florida. Members of his delegation to the U.S. were later reported to be infected.
 

Krayola

Veteran Member
I apologize if this was posted here already. I searched the thread and did not find anything so I'm going to post this so people are aware.
I ran across some info earlier this week about Metformin and felt I should post it since there are people here on the forum who probably take this drug.

The two main points are that

1) Metformin has been shown to lower fatality rate in female (not male) diabetics who contract CV19.

2) Metformin may potentially interact unfavorably with Hydroxychloriquin.


~~ Krayola


*************************************************************************************************


Diabetes drug may lower COVID-19 death risk in women

Nancy Lapid


(Reuters) -
Women taking the widely used oral diabetes medication metformin may be at lower risk for fatal COVID-19, according to a study posted on Saturday that has not yet been peer-reviewed. Among more than 6,200 adults with diabetes or obesity and commercial insurance who were hospitalized with COVID-19, there were fewer deaths among women who had filled their 90-day metformin prescriptions than among those not taking the medicine.

After adjusting for other risk factors, they were roughly 21% to 24% less likely to die of the disease. The link was not seen in men. "We know that metformin has different effects between men and women. In the diabetes prevention trial, metformin reduced CRP (the inflammation marker C-reactive protein) twice as much in women as men," study coauthor Carolyn Bramante of the University of Minnesota told Reuters. Metformin also decreases levels of TNF-alpha, an inflammation protein that appears to make COVID-19 worse, she said.

Studies have suggested metformin may bring down TNF-alpha levels to a greater extent in women than in men, she added. "The fact that we saw the benefit in women only, and the fact that metformin lowers TNF-alpha in female mice, might suggest that the TNF-alpha effects of metformin are why it helps in COVID-19," Bramante said. Formal clinical trials are needed to confirm the theories raised by this observational study. Metformin is a safe, cheap and widely available medicine, making it "a very realistic treatment" if proven in larger trials, she added. (bit.ly/317D2yi)
 

Krayola

Veteran Member
Two potential COVID-19 treatments could be deadly when combined with metformin

Written byMike Watts
Updated on 9th April 2020





Two drugs which have been linked with treating coronavirus could be deadly when combined with metformin, researchers have said.

Hydroxychloroquine (HCQ) and chloroquine (CQ) are usually used to treat malaria and autoimmune diseases, and in America the Food and Drug Administration (FDA) granted emergency approval for the two medications to be used by people who are critically ill in hospital with COVID-19.
The drugs have also shown promising outcomes in helping to treat certain cancers, but recent studies have also found combining these medications with metformin, sold as Glucophage, could be fatal.
A study which used mice to test the outcome of all three drugs, showed between 30% and 40% of the animals died.

In a statement, Chi Dang, director of the Ludwig Institute for Cancer Research and Anirban Maitra, scientific director of the Center for Pancreatic Cancer Research at MD Anderson Cancer Center, said: “Our interest in this combination arose because both drugs individually have been shown to have anti-tumour effects in pancreatic cancer.

“To our utter surprise, both HCQ and CQ when combined with metformin resulted in a surprising death rate in 30-40% of mice. In contrast there were no deaths in the single treatment groups.”
The work that was involved in the newly published study was carried out before the coronavirus outbreak, so the focus point was how the medication reacted in mice who had cancerous tumours.
The authors said: “Even in mice that did not have any tumours, we found this deleterious effect of the combination, underscoring that it is not dependent on the presence of a tumour.

“Our goal in communicating this work is not to scaremonger. We hope that the lethality we observed in mice will not translate to humans but instead there will be more ‘pharmacovigilance’ or awareness regarding potential drug interactions between HCQ/CQ and metformin.

“There is very good safety data on both drugs individually, as well as safety data on combination being used in patients who have autoimmune diseases like lupus and rheumatoid arthritis. However, patients with COVID-19 are a whole different ballgame and typically much sicker than the average population.
“We have to remember that COVID-19 has been associated with adverse effects on the heart and the blood vessels – how all of these play out in addition to the two drugs interacting with each other will need to be studied.”

The study has been published on bioRxiv, the preprint server for technology.

 

Zagdid

Veteran Member

School bus transportation presents problems for social distancing
Rebecca R. Bibbs The Herald Bulletin Jun 29, 2020

FRANKTON — As schools and districts plan for the return to in-person instruction for those families that choose it in the fall, bus service is proving to be a particularly tricky issue because of the measures necessary to keep students safe amid the COVID-19 pandemic.

Frankton-Lapel Superintendent Bobby Fields said he didn’t even bother calculating the potential cost of social distancing on his district’s fleet of 34 district-owned school buses because there was no point in the district entertaining the possibility. The district transports about 1,600 students, or about half the population, he said.

“The buses are one place where it is impossible to properly social distance. We cannot afford to, nor do we have the time to make several bus trips per day to properly social distance on school buses,” he said. “With the budget being so tight for transportation, and in many years seeing cost overruns under normal operating conditions, we knew we could not afford any scenarios that would increase transportation costs.”

Bus service is a convenience for many families, but for some who don’t own vehicles and live far from the schools, it’s crucial to their child’s ability to get an education.

However, children are a vector for disease, which is why schools and districts closed to in-person instruction around spring break as the pandemic hit Indiana. In an age in which Hoosiers are trying to slow the spread of the novel coronavirus, social distancing remains an important measure, but on school buses on a time schedule, that is nearly impossible, school officials say.

But just as impossible, superintendents in Madison County said, is making any cost-prohibitive plan that changes the routes or the number of students transported in a single trip.

In early June, the Department of Education released “Indiana’s Considerations for Learning and Safe Schools,” a document that provides guidance based on recommendations from the Centers for Disease Control and Prevention and the National Association for Pupil Transportation. Bus service is a major part of the plan, though the recommendations, such as having staff and students wear masks, are not required and may be considered unfeasible for some.

The state’s plan recommends that schools and districts work with local health departments.

It suggests schools and districts determine whether placing barriers between the driver and passengers is feasible, disinfection using products recommended by the CDC before and after each route, and waiting 24 hours before cleaning and disinfecting a vehicle that has transported someone who has tested positive for COVID-19.

“We are going to run our buses and encourage drivers and students to wear appropriate personal protective equipment. We will educate bus drivers and parents about self-screening before boarding a bus. We will also institute a more rigorous cleaning and disinfecting schedule for our buses,” Fields said.

Most school districts already report annual cost overruns in their transportation budgets.

For instance, Anderson Community Schools, which contracts for the use of 78 buses from several entities, takes in approximately $800,000 in taxes to cover roughly $4,500,000 in costs, said interim Superintendent Joe Cronk. At Alexandria Community Schools, cost overruns average about $50,000 per year, Superintendent Melissa Brisco said.

Most buses can transport around up to 70 students, depending on whether they are elementary or secondary levels.

“Given our costs, social distancing on buses just cannot be done,” Cronk said. “If we had to add additional shifts to our busing, costs go up exponentially.”

Unlike districts in other communities, such as Alexandria, ACS does not have any walk zones and transports 5,600 of its 6,600 students by bus.

Most districts have surveyed parents about their plans and needs over the pandemic period and for re-opening planning, but most of the surveys have not addressed the issue of transportation, the superintendents reported.

The one exception is Alexandria, which transports about 1,000 students daily on 18 buses, eight of which are owned by the district and transport students within the city and 10 of which are contracted through owner-operators to pick up students in rural areas. According to district policy, elementary students are provided transportation unless they live in the neighborhood surrounding the school, while secondary students are expected to walk up to a half mile to the school.

“The survey results that we have so far, approximately 38% of parents claim they will be transporting their own students,” Alexandria’s Brisco said.

One district that is considering the addition of a route to allow for better social distancing among students it transports from two towns and surrounding rural areas is Madison-Grant United School Corp.

“We are still developing procedures in the area of loading and unloading, masks, and the specific cleaning procedures after each route,” said Superintendent Scott Deetz.

Most districts, including Madison-Grant, report they plan allow students to continue to drive to school and have no plans to limit students from driving people outside their own households.

“Students with a valid license are able to drive to school. However, there is no policy that dictates who students can and cannot ride with to school,” Deetz said.
 

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=vqSMp_--nus
16:25 min
109 - COVID-19 Explained With Economist and Bestselling Author, Dr. Emily Oster
•Jul 7, 2020


Johns Hopkins Bloomberg School of Public Health
Brown University economist and bestselling author Dr. Emily Oster is probably best known for her writing about parenting and childbirth. Now, she’s taken her data-centric approach to demystify the COVID-19 pandemic on a new website, explaincovid.org. Oster talks with Stephanie Desmon about the most frequently asked questions, what the data says about childcare facilities that have remained open, how schools should approach reopening in the fall, and why this virus has been so confusing for so many.
 

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=apsBgAI0qc4
38:47 min
Knowns and unknowns about coronavirus
•Jul 7, 2020


Dr. John Campbell
Known and unknowns https://www.nature.com/articles/d4158...

First coronavirus, 10,000 to 300 million years ago Seven strains infect humans Four that cause common colds, 2 from rodents, 2 from bats SARS-CoV, bats MERS-CoV, bats SARS-CoV-2, horseshoe bats Usually an intermediary SARS, civet cats, (abused in China) MERS-CoV, Camels

SARS-CoV-2 Viral Origins Shares 96% of its genetic material with a virus found in a bat in a cave in Yunnan, China But this bat virus does not infect people Spike proteins in SARS-CoV-2 is different and more efficient

The 4% difference = decades of evolution Malayan pangolins, up to 92% of their genomes with the SARS-CoV-2 Need an animal that hosts a version more than 99% similar to SARS-CoV-2 Chinese studies found no animal intermediates https://www.nature.com/articles/d4158...

Why do people respond so differently? Infection factors Ten viral particles might be enough to get to the throat, but are likely to be cleared by mucociliary system 100 viral particles can get down to the lungs

Pneumonia of rapid onset Two infection points combining the transmissibility of the common cold coronaviruses with the lethality of MERS-CoV and SARS-CoV Therefore SARS-CoV-2 can shed viral particles into saliva even before symptoms start

Host factors Human gene variants that might explain some differences 4,000 people from Italy and Spain, respiratory failure, two particular gene variants Tuberculosis and Epstein–Barr virus, single genes.

Immunological response How good and how long? Neutralizing antibodies against SARS-CoV-2 IgM first 23 days IgG up to 49 days Longer after severe infection ?IgA Memory T lymphocytes Sterilizing immunity, may last for a few months Protective immunity, much longer

Virus mutations Mutations used to trace spread More or less virulent or transmissible Reinfection and vaccination A mutation seems to have emerged around February in Europe More infectious to cultured cells

Vaccination 200 in development worldwide 20 in clinical trials Awaiting placebo controlled trials Macaque monkeys suggest prevention of lung infection and pneumonia Neutralizing antibodies generated Vaccine could be improved over time

__________________

View: https://www.youtube.com/watch?v=WEvdkvxjB0s
26:38 min
Global Update 7th July
•Jul 7, 2020

Dr. John Campbell
COVID – 19 Global Update Global Cases, 11,645,109 Deaths, 538,780

9 lung transplants Australia https://www.telegraph.co.uk/global-he... https://www.health.gov.au/news/health... Melbourne 191 new cases in 24 hours Daniel Andrews, now too many incidents to trace and track Five million in Melbourne, to lock down for six weeks From midnight on Wednesday Victoria effectively sealed off from the rest of the country The alternative is to pretend it’s over

Do the 3, COVID safe app

US Cases, 2,938,624 Deaths, 130,306 Weekend parties and crowds Just like memorial Day, spike in 2 weeks Fighting 2 wars, (Houston Doctor on NBC) https://rt.live Thursday 25 June 39,000 Friday 26 June 45,300 Saturday 27 June 42,700 Sunday 28 June 39,000 Monday 29 June 41,400 Tuesday 30 June 45,700 Wednesday 1 July 51,200 Thursday 2 July 54,869 Friday 3 July 57,718 Saturday 4 July 52,228 Sunday 5 July 44,361

Florida https://www.youtube.com/watch?v=qT8Vy... 44 ICUs at capacity Texas 120 increase in hospitalisations Arizona Most patients under 44

Spain https://www.theguardian.com/world/202... Regional increases, 70,000 people in Galicia lockdown Increasing cases

Philippines Quarantine measures eased Cases + 2,434 = 47,873 Deaths, 1,309 Saudi Arabia Cases, + 4,000 = 213,716 Deaths, 1,968 United Arab Emirates Cases, 52,068 Deaths, 324 Plans to reopen Dubai

Israel Cases, 31,271 Deaths, 338 Yuli Edelstein, facing a second wave Cases, + 977 = 31,271 Benjamin Netanyahu, ‘We are at the height of a new corona offensive. This is a very strong outbreak that is growing and spreading in the world and also here’ Phone surveillance technology in use West Bank Residents were ordered to stay at home on Friday Cases, + 500 = 3,835

Serbia Population 9 m Cases, 16,420 Deaths, 317 Declared a state of emergency in Belgrade after surge Reimposing some restrictions Iran Cases, 243,051 Deaths, 11,731 Mandated face masks in public Voluntary social distancing not working Russia Population, 144 m Cases, 693,215 Deaths, 10,478 India Cases, 719,664 Deaths, 20,159 Mumbai, 20 m New surge Four new field hospitals, 3,500 beds

Face covering https://www.bbc.co.uk/news/uk-53316491 Late April UK, 25% Italy, 83.4% United States, 65.8% Spain, 63.8% Royal Society, Prof Ramakrishnan https://royalsociety.org/news/2020/07... Public remained sceptical about their benefits The message has not been clear enough Guidelines have been inconsistent. ‘What we would like for the government is to be a bit stronger and clearer about the messaging and require it whenever you are in crowded public spaces where you cannot get more than two metres away from the next person’ ‘anti-social’ Public transport and hospitals Scotland, mandatory on public transport, shops from 10 July World Health Organization, advised since June

Prof Paul Edelstein, University of Pennsylvania https://www.med.upenn.edu/apps/facult... Evidence that they protected other people was ‘clearer all the time’ ‘Some evidence’ they protected the wearer ‘There are people without symptoms going about their daily business who are unknowingly breathing out droplets that are carrying the virus’ ‘If they had their faces covered the majority of those droplets would be caught before they can infect other people Wearing face coverings can help save lives and prevent disabling illnesses’
 
Last edited:

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=ZS3k8y1iEcA
58:59 min
War Room Pandemic Ep 267 - Long March Through the Institutions (w/ Gerry Baker)
•Streamed live 6 hours ago

Bannon WarRoom - Citizens of the American Republic


Raheem Kassam, Jack Maxey, and Greg Manz are joined by Steve Bannon to discuss the latest on the coronavirus pandemic as the crime spike in urban centers continues with no end in sight. Gerry Baker calls in to discuss the cultural revolution taking place right.
------------------------------

View: https://www.youtube.com/watch?v=xILRtpjhtRI
58:28 min
War Room Pandemic Ep 268 - CCP's Clock Ticking
•Streamed live 5 hours ago


Bannon WarRoom - Citizens of the American Republic

Raheem Kassam, Jack Maxey, and Greg Manz are joined by Steve Bannon to discuss the latest on the coronavirus pandemic as the US Government starts positioning itself to strike back on the CCP's transgressions during the global outbreak that they helped spread.
 

marsh

On TB every waking moment
Last edited:

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=zi8EQioe21o
.56 min
Brazilian President Bolsonaro tests positive for coronavirus
•Jul 7, 2020


Fox News
Jair Bolsonaro, the president of Brazil, has tested positive for coronavirus. Bolsonaro has repeatedly down played the severity of the virus calling it “a little flu” and when asked what he would say to Brazilians who have suffered from the pandemic, he said death is “everyone’s destiny.”
 

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=GFkd8Ei0UEc
1:01:14 min
Peter Sandman: How Your Ability To Process Risk Can Save Your Life
•Jul 7, 2020


Peak Prosperity

How much do things around you need to change before you start changing your behavior?

Dr. Peter Sandman has made a career out of analyzing people's "adjustment reaction" process. And it turns out, people are wired differently.

Some watch the world intently, looking for early indicators of change and reacting swiftly to them. Others prefer not to get distracted by the "small stuff" and only pay attention once change is forced on them.

Neither approach is inherently right or wrong, but the difference often sets us up for conflict and confrontation when big risks are involved. Those who argue for swift, extreme action are resisted by the side not convinced change is necessary -- as the covid-19 pandemic has clearly revealed. Families have been divided and long-term friendships ended as the "Masks for everyone!" and "It's just the flu, bro!" camps have gone to war.

Dr. Sandman is a top world expert on risk communication. In today's podcast, he explains the fundamentals for mobilizing people when risk is involved and why the US has done such a poor job of it so far with the pandemic.
 

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=1BT4uxLeElM
.28 min
Is Coronavirus More Airborne Than We Thought? Scientists Speak Out | TODAY
•Jul 7, 2020


TODAY

As coronavirus cases surge across the nation, scientists are questioning whether the virus is more airborne than was originally thought. NBC’s Gabe Gutierrez reports for TODAY from New York City.

-------------------

View: https://www.youtube.com/watch?v=7R5-P6UEwVI
3:39 min
Scientists say coronavirus can be spread farther than 6 feet in tiny airborne particles
•Jul 7, 2020


CBS This Morning

More than 200 scientists are asking the World Health Organization to update its guidance on how the coronavirus spreads in the air. They say fine particles may travel farther than six feet and fear current advice may not promote multiple layers of protection. Dr. Jon LaPook reports.

______________________________

View: https://www.youtube.com/watch?v=vMVdZWJWZA0
6:00 min
Scientists suggest coronavirus is airborne, ask WHO to change recommendations
•Jul 6, 2020

CBC News Canada

The World Health Organization has said the coronavirus spreads primarily from person to person through small droplets expelled when a person with COVID-19 coughs, sneezes or speaks. Now, hundreds of scientists are saying there is evidence that the virus is airborne and are calling for the WHO to revise its recommendations.
 
Last edited:

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=Q6xPUjLf-tg
LIVE
Online Event: Japan’s Response to Covid-19 and Potential Lessons Learned for Latin America
•Started streaming 51 minutes ago


Center for Strategic & International Studies

Japan’s pandemic response is worth studying. The government reacted early and proactively to contain the virus’ initial spread, and the general population’s commitments to personal health and hygiene have continued to limit disease transmission. Patients in need have been consistently served by the country’s national health insurance system, efficient public health administration, and advanced clinical capacities. Japan has controlled the pandemic even despite its unusually aged society and high urban population concentration, providing a template for other countries assembling disease responses.

Now at the epicenter of the global pandemic, Latin America could benefit from Japan’s insights on handling Covid-19. Well-coordinated Covid-19 responses are medically, strategically, economically, and politically crucial to governments grappling with pandemic fallout. Looking to share expertise, the Japanese International Cooperation Agency (JICA) is already aiding low- and middle-income countries’ efforts to build resilient, inclusive healthcare systems and societies.

During this event, JICA Vice President Dr. Takao Toda will outline the key tenets of Japan’s response to the pandemic, and an expert panel will address potential takeaways from Latin America. The panel will include Michael Green, CSIS Senior Vice President for Asia and holds the CSIS Japan Chair, as well as Katie Taylor, Executive Director for the Pan-American Development Foundation.

 

marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=cpR1KJvo2po
2:58 min
How state economies are fairing amid coronavirus crisis
•Jul 7, 2020


CNBC Television


The Covid-19 pandemic has dealt a body blow to the states. Not only did the economy shut down, but states are dealing with the massive costs of fighting the disease. CNBC's Scott Cohn takes a look at how state economies are faring amid the crisis.

____________________

View: https://www.youtube.com/watch?v=OH4UbXrgYhU
2:42 min
Covid-19 and The Economy: What You Need to Know - Steve Forbes | What's Ahead | Forbes
•Jul 7, 2020

Forbes

As new coronavirus outbreaks plague the U.S., observers worry that the economic revival will be disrupted, but what are the factors that must be considered? Steve Forbes on the increase in testing, the upswing in economic activity and stock market trends amidst the pandemic.
 

Mixin

Veteran Member
Experts fear Indiana in early stage of COVID-19 resurgence
by: Russ McQuaid
Posted: Jul 7, 2020 / 03:41 PM EDT / Updated: Jul 7, 2020 / 03:41 PM EDT

The numbers reported by the Indiana State Department of Health over the last month show Indiana and Marion County may be on the front end of a resurgence of coronavirus cases.

Dr. Ram Yeleti, Chief Executive Physician of the Community Health Network, was just getting back up to full speed last month after his own personal bout with COVID-19 when he took a look at where Indiana had been and where it was going in the campaign against the novel coronavirus.

“Honestly, back in June, I was thinking that by July and August we’ll actually be in pretty good shape,” he said, “but we’ve actually in the past ten days looked at everything and we are prepared for increased hospitalizations in the next four to six weeks.”

During the last ten days of June, the state’s daily positive infection rate was 4.6%. So far this month, that number is 6.8%.

In Marion County, June ended with a daily positive infection rate of 4.7%. During the first week of July in Indianapolis, the statistic has jumped to 7.1%.

Experts don’t see that daily positive infection number going down any time in the near future.

“I do think it’s the beginning of a trend,” said Dr. David Dunkle, President and CEO of Johnson Memorial Health in Franklin. “I do think it’s obvious that if you go out in public, people are letting their guard down. Social distancing, wearing masks, it seems as if people have forgotten what’s important about stemming the rise of this illness. People need to go back to being vigilant.”

“I think the fear may be now that we may be on the beginning part of that upsurge,” said Dr. Brian Dixon of Regenstrief Institute. “History would suggest that in any of these sort of pandemics or large outbreaks of disease that there’s often a fall before a second wave.”

Dr. Dixon said that the resurgence in statewide statistics may be due to infections showing up in pockets of Indiana that escaped the first wave of coronavirus cases.

“Around the state, there are a couple of localized outbreaks that have occurred,” he said. “One is sort of in the northeast corner near Fort Wayne and the other one is near Evansville, Indiana.”

While Dr. Dixon can’t point to a specific event or date on a calendar that led to the resurgence, he said the virus is now striking more young people than earlier in the outbreak.

“These younger individuals are about fifty percent of those testing positive right now,” he said, “whereas in March and April, younger people between twenty and forty years of age, they were making up about twenty percent of the people who were testing positive, now it’s about half of those people who were testing positive.”

Dr. Dixon said that he doesn’t necessarily expect hospitalization and death rates to keep pace with the spread of the pandemic to younger Hoosiers because the newly infected group is generally healthier and better able to withstand the impact of the disease.

********************
They can't figure what's going on in Elkhart County, either.

ISDH sending CDC team to investigate Elkhart County coronavirus spike
by Ed Ernstes, WSBT 22 Reporter
Monday, July 6th 2020

 

Green Co.

Administrator
_______________
Texas passes 10,000 confirmed new virus cases in single day

AUSTIN, Texas (AP) — Texas surpassed 10,000 new coronavirus cases in a single day Tuesday for the first time, crossing a sobering milestone rarely seen since the pandemic first hit the U.S. in March.

The record high of 10,028 new cases in Texas served as another alarming new measure of the swift resurgence of COVID-19 nationwide and the failures of the country’s response. Republican Gov. Greg Abbott of Texas aggressively began one of America’s fastest reopenings in May but has begun reversing course in recent weeks, ordering bars closed and mandating face coverings.

New York and Florida are the only other states to record more than 10,000 new cases in a single day. New York hit that grim total back in April, when New York City hospitals were overwhelmed and hundreds of people were dying every day. Florida topped 10,000 confirmed cases last week.


The record mark in Texas partly reflects a lag in testing results from the Fourth of July weekend, when newly reported cases were far below what Texas has seen in recent weeks. But Abbott said the numbers should still be “an alarm bell for everybody” who is skeptical about whether the virus is a threat.

“We have rapid spread of COVID-19 in the state of Texas right now,” Abbott told San Antonio television station KENS.

Later in the interview, Abbott was noncommittal about whether he would attend his own party's convention next week in Houston, which the Texas GOP has remained bent on holding even as the mayor, doctors and businesses pressure the party to cancel. Houston has emerged as one of the nation's hot zones in the pandemic. However, Republican activists, some of whom have called the fears overblown, have resolved to press forward with the indoor three-day convention.

Texas surged past 8,000 statewide hospitalizations for the first time over the long holiday weekend — a more than quadruple increase on the past month. On Tuesday, the number of hospitalizations soared past 9,000. Texas also set a new high for deaths in a single day with 60.

Mayors in some of the biggest cities in the state and U.S. — including Austin, San Antonio and Houston — have warned that hospitals could soon become overwhelmed with coronavirus patients. Along the Texas-Mexico border, some cities imposed curfew orders in hopes of cutting down on large parties or social gatherings as cases have skyrocketed.

“Many of us are running at capacity and have created new wards,” said Michael Mann, the chief executive officer at McAllen Medical Center, which on Tuesday had more than 130 coronavirus patients taking up more than half of the facility's beds. “The physical space is obviously limited, and most of the hospitals are running out of that pretty quickly.”

The record count was reported on a day that also saw the State Fair of Texas canceled for the the first time since World War II. Fair organizers said the event, which draws more than a million visitors to Dallas each fall, was not feasible during the pandemic.

Deaths remain lower in Texas compared to other big states.
As of Tuesday, Texas has confirmed that at least 2,715 people have died due to COVID-19. But fatalities have climbed in recent days, and in addition to an alarming acceleration in new cases in Texas, the seven-day infection rate has climbed to 13.5%.

The number of infections is likely far higher because many people haven't been tested, and studies suggest people can be infected without feeling sick.

 

psychgirl

Has No Life - Lives on TB
Experts fear Indiana in early stage of COVID-19 resurgence
by: Russ McQuaid
Posted: Jul 7, 2020 / 03:41 PM EDT / Updated: Jul 7, 2020 / 03:41 PM EDT

The numbers reported by the Indiana State Department of Health over the last month show Indiana and Marion County may be on the front end of a resurgence of coronavirus cases.

Dr. Ram Yeleti, Chief Executive Physician of the Community Health Network, was just getting back up to full speed last month after his own personal bout with COVID-19 when he took a look at where Indiana had been and where it was going in the campaign against the novel coronavirus.

“Honestly, back in June, I was thinking that by July and August we’ll actually be in pretty good shape,” he said, “but we’ve actually in the past ten days looked at everything and we are prepared for increased hospitalizations in the next four to six weeks.”

During the last ten days of June, the state’s daily positive infection rate was 4.6%. So far this month, that number is 6.8%.

In Marion County, June ended with a daily positive infection rate of 4.7%. During the first week of July in Indianapolis, the statistic has jumped to 7.1%.

Experts don’t see that daily positive infection number going down any time in the near future.

“I do think it’s the beginning of a trend,” said Dr. David Dunkle, President and CEO of Johnson Memorial Health in Franklin. “I do think it’s obvious that if you go out in public, people are letting their guard down. Social distancing, wearing masks, it seems as if people have forgotten what’s important about stemming the rise of this illness. People need to go back to being vigilant.”

“I think the fear may be now that we may be on the beginning part of that upsurge,” said Dr. Brian Dixon of Regenstrief Institute. “History would suggest that in any of these sort of pandemics or large outbreaks of disease that there’s often a fall before a second wave.”

Dr. Dixon said that the resurgence in statewide statistics may be due to infections showing up in pockets of Indiana that escaped the first wave of coronavirus cases.

“Around the state, there are a couple of localized outbreaks that have occurred,” he said. “One is sort of in the northeast corner near Fort Wayne and the other one is near Evansville, Indiana.”

While Dr. Dixon can’t point to a specific event or date on a calendar that led to the resurgence, he said the virus is now striking more young people than earlier in the outbreak.

“These younger individuals are about fifty percent of those testing positive right now,” he said, “whereas in March and April, younger people between twenty and forty years of age, they were making up about twenty percent of the people who were testing positive, now it’s about half of those people who were testing positive.”

Dr. Dixon said that he doesn’t necessarily expect hospitalization and death rates to keep pace with the spread of the pandemic to younger Hoosiers because the newly infected group is generally healthier and better able to withstand the impact of the disease.

********************
They can't figure what's going on in Elkhart County, either.

ISDH sending CDC team to investigate Elkhart County coronavirus spike
by Ed Ernstes, WSBT 22 Reporter
Monday, July 6th 2020


This is the first I’m hearing about Elkhart! I didn’t realize numbers were that bad there.
 

Stanb999

Inactive
Your all caught in a media storm that has no meaning... The only chart that matters..

Stop listen to the news and being programed.
 

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marsh

On TB every waking moment
View: https://www.youtube.com/watch?v=1plkwhi5KUE
43:21 min
Covid-19: Vindication! HCQ+ & Ivermectin Work!
•Premiered 5 hours ago

Peak Prosperity
Wow -- a lot to cover in today's video update.

First: high fives all around for fans of quality science! Our months' long position that hydroxcholorquine+azithromycin+zinc and ivermectin showed strong promise as cheap, effective treatments vs covid-19 now appears to be proven correct.

Of course, up until this point, the media has parroted "junk science" talking points designed to malign and vilify these treatment candidates, very likely on behalf of Big Pharma who can't reap $billions off of them. And in the meantime, millions of sick patients worldwide have likely been denied these drugs as a result.

How many people have died/suffered as a result?

Other big developments to note: covid-19 appears to have mutated into a more contagious strain, more evidence is mounting that the virus spreads in an airborne manner, and it seems herd immunity without a vaccine may be harder to achieve than previously anticipated.

All this leads us to maintain our expectation that the world has a long way to go yet before the pandemic is anywhere near "under control".

______ LINKS FROM THIS VIDEO: Fauci Late to Mutation Party https://nypost.com/2020/07/03/fauci-w... Airborne! https://www.nytimes.com/2020/07/04/he... HCQ Reduces death rate by half https://www.detroitnews.com/story/new... Still not the HCQ study we’re looking for https://www.ijidonline.com/action/sho... Not the flu – Cordero https://fox6now.com/2020/07/05/tmz-br... Spain’s giant seroprevalence testing https://twitter.com/DiseaseEcology/st...
 

Richard

TB Fanatic
This is a simple observation that I suspect has been made before, many countries are behind the loop compared with Europe, e.g. Brazil, Mexico, Pakistan, South Africa etc. They have yet to reach the peak of their outbreaks, this will mean that the pandemic world wide will last at least another month to 6 weeks and the total number of deaths and cases will double. Some countries will be recovering whilst others will be in the full swing of the pandemic. Doing this period continued appropriate travel bans should be in force.

Any thoughts, agree or disagree?
 
Last edited:

IdahoMom

Contributing Member
After Reopening Schools, Israel Orders Them To Shut If COVID-19 Cases Are Discovered
June 3, 202011:32 AM ET
Daniel Estrin
DANIEL ESTRIN

InstagramTwitter
gettyimages-1213417626_wide-c7c6ea15c57113564e55a3376d595db3a0fd0eca-s800-c85.jpg


Students wear masks May 17 outside a school in the Israeli city of Modiin. Israeli students in all grades went back to school last month.

Two weeks after Israel fully reopened schools, a COVID-19 outbreak sweeping through classrooms — including at least 130 cases at a single school — has led officials to close dozens of schools where students and staff were infected. A new policy orders any school where a virus case emerges to close.

The government decision, announced Wednesday evening, comes after more than 200 cases have been confirmed among students and staff at various schools. At least 244 students and school employees have tested positive for the coronavirus, according to the Ministry of Education. At least 42 kindergartens and schools have been shuttered indefinitely. More than 6,800 students and teachers are in home quarantine by government order.

It's an abrupt reversal of the post-pandemic spirit in Israel as officials lifted most remaining coronavirus restrictions last week. With fewer than 300 deaths in Israel, Prime Minister Benjamin Netanyahu had declared victory in early May over the pandemic and last week told Israelis to go to restaurants and "enjoy yourselves."

But by the weekend, the spike in cases led him to consider reimposing restrictions, including closing all schools. The education minister, Yoav Gallant, argued that the overall number of virus cases in Israeli schools remains low and closing them all would not be justified


Schools first began to reopen in early May, with classes staggered in smaller groups or "capsules" of students to prevent a wide outbreak. By May 17, limitations on class size were lifted.

The most significant outbreak appeared last week in the Gymnasia Rehavia, a historic middle and high school in Jerusalem. There, 116 students and 14 teachers were infected, according to the Ministry of Education, and the school closed. Built in 1928, its graduates include prominent novelists, politicians and Netanyahu's late brother.

Health officials said they're investigating how the virus spread there. A teacher told NPR a seventh-grader was first discovered to be carrying the virus and the entire grade was ordered to quarantine at home. Then a ninth-grader tested positive, and the school was shut down.

"It was a mistake to go back to school in this format," the teacher said. She spoke on condition of anonymity because teachers were ordered not to speak with the press and she feared losing her job if identified.

Across Israel, many parents have yanked their children from schools that remain open. When the Collège des Frères, a French Roman Catholic school in the city of Jaffa, announced that the father of some students had tested positive for the virus, his children's classmates were sent home — but other parents pulled their children out, too.

Dr. Arnon Afek, who is helping manage Israel's coronavirus response, played down the outbreak, saying a spike in cases was expected when schools reopened. "It wasn't a surprise," he said. "It happened also in South Korea and Singapore."
 

Heliobas Disciple

TB Fanatic
This is a simple observation that I suspect has been made before, many countries are behind the loop compared with Europe, e.g. Brazil, Mexico, Pakistan, South Africa etc. They have yet to reach the peak of their outbreaks, this will mean that the pandemic world wide will last at least another month to 6 weeks and the total number of deaths and cases will double. Some countries will be recovering whilst others will be in the full swing of the pandemic. Doing this period continued appropriate travel bans should be in force. Any thoughts, agree or disagree?

I would add India and Russia to your list. I don't think this is going to be over in a month to 6 weeks, this is going to go on for a while longer than that. Especially if people won't wear a mask. I do agree with travel bans, ironically it's the Americans being banned from Europe at the moment. We'd be a lot better off if a travel ban of China was instituted back in January.

HD
 

Heliobas Disciple

TB Fanatic
After Reopening Schools, Israel Orders Them To Shut If COVID-19 Cases Are Discovered
June 3, 202011:32 AM ET
Daniel Estrin
DANIEL ESTRIN

InstagramTwitter
gettyimages-1213417626_wide-c7c6ea15c57113564e55a3376d595db3a0fd0eca-s800-c85.jpg


Students wear masks May 17 outside a school in the Israeli city of Modiin. Israeli students in all grades went back to school last month.

Two weeks after Israel fully reopened schools, a COVID-19 outbreak sweeping through classrooms — including at least 130 cases at a single school — has led officials to close dozens of schools where students and staff were infected. A new policy orders any school where a virus case emerges to close.

The government decision, announced Wednesday evening, comes after more than 200 cases have been confirmed among students and staff at various schools. At least 244 students and school employees have tested positive for the coronavirus, according to the Ministry of Education. At least 42 kindergartens and schools have been shuttered indefinitely. More than 6,800 students and teachers are in home quarantine by government order.

It's an abrupt reversal of the post-pandemic spirit in Israel as officials lifted most remaining coronavirus restrictions last week. With fewer than 300 deaths in Israel, Prime Minister Benjamin Netanyahu had declared victory in early May over the pandemic and last week told Israelis to go to restaurants and "enjoy yourselves."

But by the weekend, the spike in cases led him to consider reimposing restrictions, including closing all schools. The education minister, Yoav Gallant, argued that the overall number of virus cases in Israeli schools remains low and closing them all would not be justified


Schools first began to reopen in early May, with classes staggered in smaller groups or "capsules" of students to prevent a wide outbreak. By May 17, limitations on class size were lifted.

The most significant outbreak appeared last week in the Gymnasia Rehavia, a historic middle and high school in Jerusalem. There, 116 students and 14 teachers were infected, according to the Ministry of Education, and the school closed. Built in 1928, its graduates include prominent novelists, politicians and Netanyahu's late brother.

Health officials said they're investigating how the virus spread there. A teacher told NPR a seventh-grader was first discovered to be carrying the virus and the entire grade was ordered to quarantine at home. Then a ninth-grader tested positive, and the school was shut down.

"It was a mistake to go back to school in this format," the teacher said. She spoke on condition of anonymity because teachers were ordered not to speak with the press and she feared losing her job if identified.

Across Israel, many parents have yanked their children from schools that remain open. When the Collège des Frères, a French Roman Catholic school in the city of Jaffa, announced that the father of some students had tested positive for the virus, his children's classmates were sent home — but other parents pulled their children out, too.

Dr. Arnon Afek, who is helping manage Israel's coronavirus response, played down the outbreak, saying a spike in cases was expected when schools reopened. "It wasn't a surprise," he said. "It happened also in South Korea and Singapore."

You'd think Pres Trump and the governors who are rushing to reopen schools would look at this as a warning, but they won't. They're going to press ahead and keep this pandemic fueled, instead of putting it out.

HD
 

Heliobas Disciple

TB Fanatic
(fair use applies)

How blood type may affect your coronavirus risk
Jacqueline Stenson (NBC News)
Jul 7th 2020 8:07AM

Recent studies have suggested that people's blood types may affect their risk of contracting the COVID-19 virus or developing a serious case of the disease. Overall, the findings indicate that people with Type O blood seem to be more protected and that those with Type A appear more vulnerable.

So does that mean some people can slack off on preventive measures while others need to ratchet them up?

Not so fast, say doctors who point out that the findings show associations, not causation — and don't indicate that any particular blood type guarantees protection.

While the findings may catch the public's attention at a time when people fatigued by the pandemic are looking for signs of hope, doctors say the results are more relevant to researchers trying to better understand the virus.

"I think something like this has much more sex appeal than it does real practical value," said Dr. Aaron Glatt, chair of medicine and chief of infectious diseases at Mount Sinai South Nassau in New York.

Any possible influence of blood type on COVID-19 appears small compared with the substantial impact of known risk factors, such as older age and underlying health conditions, said Glatt, who is a spokesperson for the Infectious Diseases Society of America. "In any individual patient, if they have risk factors or they don't have risk factors, that is far, far more important," he said.

People shouldn't jump to conclusions that they are safer or not because of their blood types, he said.

"They certainly shouldn't walk around high-fiving and saying, 'I can do whatever I want, I don't have to mask, I don't have to worry about anything because I have O,'" Glatt said. "And they shouldn't crawl into a corner of the world and not let anyone near them because they have A. Everybody should practice exactly the same way, whatever your blood type is, in terms of appropriate masking and social distancing."

Dr. Lewis Kaplan, a professor of surgery at the University of Pennsylvania who is president of the Society of Critical Care Medicine, agreed.

Even if some people have reduced risks based on blood type — and the risks vary by study — they don't have zero risk, Kaplan said. "It might mean they have less risk, but if you engage in risky behavior, we don't know just how much risk you need to incur to overwhelm whatever potential protection you might have," he said. "We have no clue."

A European study published last month in the New England Journal of Medicine found that people with Type A blood were 45 percent more likely to develop severe COVID-19 requiring oxygen supplementation or a ventilator than people with other blood types and that those with Type O blood were 35 percent less likely. The study involved 1,610 patients with severe COVID-19 and 2,205 control subjects.

But people with Type O can still get very sick.

"They have a decreased risk to get infected and to develop severe disease," study author Andre Franke, a professor of molecular medicine at the University of Kiel in Germany, said in an email. "However, this is only a relative risk reduction, i.e. there is no full protection. Among our patients who died there were also many with blood group O."

A couple of related papers have been released on the preprint server medRxiv without the peer review scrutiny that published papers typically receive. Studies in China and New York both found that people with Type A blood had a greater risk of coronavirus infection than those with other blood types, while those with Type O had a lower risk.

And the gene testing company 23andMe wrote a blog post about preliminary unpublished data suggesting that people with Type O blood were less likely to test positive for the coronavirus than others.

Dr. Roy Silverstein, a professor and chair of medicine at the Medical College of Wisconsin who is senior investigator at Versiti Blood Center of Wisconsin, cautioned against putting too much weight on findings that haven't been peer-reviewed and said more research is needed.

"We have to be careful about overreacting," Silverstein said.

Blood types O and A are most common, so the studies were able to draw stronger statistical conclusions about those types than B and AB, he said.

An explanation for the findings isn't known, but there is speculation that blood type may affect clotting or other factors in COVID-19 patients or somehow affect infectivity or immunity. The hope is that the findings can be applied to future research to better understand why the coronavirus affects people differently and to develop treatments.

The results aren't expected to alter how doctors care for patients now.

"The fact that you have O or A is not going to change one iota how we monitor a patient," said Glatt, of Mount Sinai South Nassau. "If somebody has O and they're not doing well, I'm not going to say, 'Oh, don't worry about it, you have O.' I would treat them appropriately. And if they have A and they're doing very well, I would say, 'OK, we're going to continue to watch you.'"

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