forpetesake
Senior Member
I have 1000C sarracenia purpurea. Does anyone know what the dose should be?
MNKYPOX MonkeyPox Treatment & Prevention [No Politics / No Reporting / No News]
- Thread starter phloydius
- Start date
rob0126
Veteran Member
Excellent!
Mupirocin is an antibiotic ointment that does require a Rx by the way.
It does treat Staph infections amd/or bacterial preventions in skin issues.
We use it at work. Hmmm…I could always ask, right?
Dont forget colloidal silver for staph, mrsa, and a multitude of other nasties.
Effects of silver nanoparticles on Staphylococcus aureus contaminated open wounds healing in mice: An experimental study
The microorganisms have been noted as the main cause of delayed wound healing. The most common pathogen causing the wound infections is Staphylococcus aureus. Silver nanoparticles (AgNPs) show ample antibacterial activities. In the present study, the ...
www.ncbi.nlm.nih.gov
This one has some interesting remarks on case studies with MRSA, noted further down the webpage.
Colloidal Silver Cures MRSA Report
Newspaper headlines around the world are now ablaze with warnings from the health authorities regarding the rapid spread of the deadly flesh-eating MRSA (methicillin resistant staphylococcus aureus) and a number of other drug-resistant 'super pathogens' that are now steadily moving into the...
www.colloidalsilvercuresmrsa.com
phloydius
Veteran Member
From site:
During the infectious period of time, body fluids, respiratory secretions, and lesion material from people with monkeypox can contaminate the environment. Poxviruses can survive in linens, clothing and on environmental surfaces, particularly when in dark, cool, and low humidity environments. In one study, investigators found live virus 15 days after a patient’s home was left unoccupied. Studies show that other closely related Orthopoxviruses can survive in an environment, similar to a household, for weeks or months. Porous materials (bedding, clothing, etc.) may harbor live virus for longer periods of time than non-porous (plastic, glass, metal) surfaces.
Orthopoxviruses are very sensitive to UV light. Despite the ability of Orthopoxviruses to persist in the environment, they are also sensitive to many disinfectants, and disinfection is recommended for all areas (such as home and vehicle) where a person with monkeypox has spent time, as well as, for items considered to be potentially contaminated.
ISOLATING ALONE IN HOME: People with monkeypox who are isolating alone at home should regularly clean and disinfect the spaces they occupy, including commonly touched surfaces and items, to limit household contamination. Perform hand hygiene afterwards using an alcohol-based hand rub (ABHR) that contains at least 60% alcohol, or soap and water if ABHR is unavailable.
If cleaning and disinfection is done by someone other than the person with monkeypox, that person should wear, at a minimum, disposable medical gloves and a respirator or well-fitting mask.
Standard clothing that fully covers the skin should be worn, and then immediately laundered according to recommendations below.
Hand hygiene should be performed using an ABHR, or soap and water if ABHR is unavailable.
Focus on disinfecting items and surfaces that were in direct contact with the skin of the person with monkeypox, or often in the presence of the person with monkeypox, during isolation. If unsure, disinfect.
Do not dry dust or sweep as this may spread infectious particles.
Wet cleaning methods are preferred such as disinfectant wipes, sprays, and mopping.
Vacuuming is acceptable using a vacuum with a high-efficiency air filter. If not available, ensure the person vacuuming wears a well-fitting mask or respirator.
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bw
Fringe Ranger
That's a homeopathic dilution. You can't take enough to matter, IMO.
bw
Fringe Ranger
Not my field, sorry. Might try a search for 'homeopathic dilution'. I understand lower numbers are less diluted, but that's the limit of my info.
For the most part folks are going to have mild disease. Just focus on treating the symptoms. Fever = Tylenol, plenty of fluids, etc. If you get it and have lesions on the face, near the eyes I'd get evaluated and get on some antivirals. Mupirocin ointment on the blisters themselves is probably not a good idea as it can be pretty harsh and increases the risk of the pustules breaking and then leading to secondary infection. Tea tree oil may have the same effect as well as it will likely not be too pleasant to apply. If you have had staph in the past putting some of the mupirocin in the outer portion of the nose may be worthwhile as that is the primary location of staph aureus in carriers.
Basically treat it like a bad case of shingles.
Basically treat it like a bad case of shingles.
bw
Fringe Ranger
Like WuFlu - it makes sense that the disease will span a spectrum.
My wife and I just got over what I presume was WuFlu, probably omicron, never got tested so it's just a guess. I've had worse colds. She lost her sense of taste for a few days, little vertigo. Meh.
Problem is, you don't know what your experience is going to be until you're experiencing it. So prep for bad, hope for good, and meanwhile life goes on.
Fairwillows
Where I am supposed to be.
Your reply prompted a memory of getting silver nitrate for bad burns. It might be beneficial for the Pox. Anyone know for sure? I'm sure someone on here has used this or has input on it's value to include it in our preps.
It's available at ADC!
Silverex Ionic 20gm Online | Buy At AlldayChemist
Buy Silverex Ionic 20gm online from AllDayChemist - your most reliable online pharmacy. Avail best price in USA, by your doorsteps. Order Now!
www.alldaychemist.com
Silvadene Topical: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for Silvadene topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
www.webmd.com
Uses (NOT TO BE TAKEN INTERNALLY)
This medication is used with other treatments to help prevent and treat wound infections in patients with serious burns. Silver sulfadiazine works by stopping the growth of bacteria that may infect an open wound. This helps to decrease the risk of the bacteria spreading to surrounding skin, or to the blood where it can cause a serious blood infection (sepsis). Silver sulfadiazine belongs to a class of drugs known as sulfa antibiotics.Silver sulfadiazine must not be used on premature babies or on newborns during the first 2 months of life because of the risk of serious side effects.
How to use Silvadene Cream
This medication is for use on the skin only. Avoid using this medication around your eyes unless directed to do so by your doctor.
Your health care professional will clean and remove the dead tissue from the wound to help the healing process.
Apply this medication to the wound using sterile technique (such as wearing sterile gloves and using sterile application tools), as directed by your doctor, usually 1 to 2 times daily. The layer of medication should be about one-sixteenth of an inch (1-2 millimeters) thick or as directed. The wound should be covered with the cream at all times. Dressings may be applied over the cream, but only if needed. If some of the cream rubs off the wound, reapply it immediately. The cream should also be reapplied immediately after hydrotherapy.
Treatment usually continues until the wound is completely healed or until the site is ready for skin grafting.
Precautions
Before using silver sulfadiazine, tell your doctor or pharmacist if you are allergic to it; or to other sulfa antibiotics (such as sulfamethoxazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain enzyme deficiency (G6PD or glucose-6-phosphate dehydrogenase deficiency), kidney problems, liver problems, low white blood cell count.
Side Effects
Pain, burning, or itching of the treated skin may occur. Skin and mucous membranes (such as the gums) may become blue/gray in color. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these rare but serious side effects occur: signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding, signs of anemia (such as unusual tiredness/weakness, rapid breathing, fast heartbeat), signs of kidney problems (such as change in the amount of urine, pink/bloody urine), signs of liver problems (such as nausea that doesn't go away, stomach/abdominal pain, vomiting, dark urine, yellowing eyes/skin), mental/mood changes.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Interactions
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Some products that may interact with this drug include: cimetidine, skin products containing sodium sulfacetamide, enzyme products used to break down and remove dead skin/tissue from burns and wounds (such as collagenase, papain, trypsin).
SageRock
Veteran Member
From the British Medical Journal, January 31, 1863
Treatment of Small-Pox by Sarracenia Purpurea
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324703/pdf/brmedj05956-0023a.pdf
Treatment of Small-Pox by Sarracenia Purpurea
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324703/pdf/brmedj05956-0023a.pdf
SageRock
Veteran Member
Detailed information on the preparation and dosing of the Sarracenia purpurea treatment for smallpox found in references within this article:
In Vitro Characterization of a Nineteenth-Century Therapy for Smallpox
This reference from the article has the detail on preparation and use:
1. Miles HS. On the employment of the Sarracenia purpurea, or Indian Pitcher Plant, as a remedy for smallpox. The Lancet. 1862;80:430–431. [Google Scholar]
To summarize: only the root of the plant is useful as a remedy. The native peoples would collect and dry the roots, the thin fibers around the root pared away, and only the solid root used. To make the decoction, slice one to two ounces of the solid root into thin pieces. The natives would place the root in an earthen pot with a quart of cold water and then simmered the liquid for two to three hours, "so as to lose one-fourth of its weight." The native peoples repeatedly asserted that the fresh root was not as powerful as the dried root.
To treat the patient, a "wine glass" amount of the decoction would be given every 4 to 6 hours. Most patients rapidly improved, and the pustules receded such that the smallpox did not cause pitting of the skin. The native peoples asserted that the patient "knows there is a great change within him at once."
The plant Sarracenia purpurea grows wild in bogs along the east coast. From the article with the above reference:
"Before human development, S. purpurea, also known as Huntsman's Cup, Side-saddle flower or Indian Pitcher Plant, was widely distributed ranging from Labrador to Florida along the Atlantic seacoast of North America and westward to Wisconsin and Minnesota [13], [14]. S. purpurea is an insectivorous bog plant, the leaves of which form cups and become filled with water to capture insects."
Perhaps some members of TB2K live near areas where the plant can be gathered and can create this remedy for themselves and their household.
Here is the PDF for the Lancet article from 1862.
In Vitro Characterization of a Nineteenth-Century Therapy for Smallpox
This reference from the article has the detail on preparation and use:
1. Miles HS. On the employment of the Sarracenia purpurea, or Indian Pitcher Plant, as a remedy for smallpox. The Lancet. 1862;80:430–431. [Google Scholar]
To summarize: only the root of the plant is useful as a remedy. The native peoples would collect and dry the roots, the thin fibers around the root pared away, and only the solid root used. To make the decoction, slice one to two ounces of the solid root into thin pieces. The natives would place the root in an earthen pot with a quart of cold water and then simmered the liquid for two to three hours, "so as to lose one-fourth of its weight." The native peoples repeatedly asserted that the fresh root was not as powerful as the dried root.
To treat the patient, a "wine glass" amount of the decoction would be given every 4 to 6 hours. Most patients rapidly improved, and the pustules receded such that the smallpox did not cause pitting of the skin. The native peoples asserted that the patient "knows there is a great change within him at once."
The plant Sarracenia purpurea grows wild in bogs along the east coast. From the article with the above reference:
"Before human development, S. purpurea, also known as Huntsman's Cup, Side-saddle flower or Indian Pitcher Plant, was widely distributed ranging from Labrador to Florida along the Atlantic seacoast of North America and westward to Wisconsin and Minnesota [13], [14]. S. purpurea is an insectivorous bog plant, the leaves of which form cups and become filled with water to capture insects."
Perhaps some members of TB2K live near areas where the plant can be gathered and can create this remedy for themselves and their household.
Here is the PDF for the Lancet article from 1862.
Last edited:
SageRock
Veteran Member
More useful information from the same article -- it's a very long and technical article, and I've excerpted several paragraphs that seem of particular interest and also seem more readable and approachable.
In Vitro Characterization of a Nineteenth-Century Therapy for Smallpox
"In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections. The work described characterizes the antipoxvirus activity associated with this botanical extract against vaccinia virus, monkeypox virus and variola virus, the causative agent of smallpox. Our work demonstrates the in vitro characterization of Sarracenia purpurea as the first effective inhibitor of poxvirus replication at the level of early viral transcription. With the renewed threat of poxvirus-related infections, our results indicate Sarracenia purpurea may act as another defensive measure against Orthopoxvirus infections."
"In the late 1800's, the Micmac Indians of Nova Scotia proclaimed the existence of a botanical-based remedy for smallpox. During this time, Herbert Miles, the Assistant Surgeon to the Royal Artillery, reported that during an outbreak of smallpox “an old squaw going amongst them, and treating the cases with (a botanical) infusion…was so successful as to cure every case”. This botanical infusion was later described as being derived from the carnivorous plant, Sarracenia purpurea [1], [2].
In 1892, Charles Millspaugh described that the Native Americans of eastern North America used S. purpurea as a poultice against smallpox and it provided “the greatest remedy known for the dreadful scourge” [3]. C.G. Logie, Surgeon-Major of the Royal Horse Guards, treated variola-infected men in his regiment and found that S. purpurea “seemed to arrest the development of the pustules, killing, as it were, the virus from within, thereby changing the character of the disease and doing away with the cause of pitting” [4]. However, the putative medicinal properties of S. purpurea have been largely forgotten."
The authors of this article found that this remedy is as effective against Monkeypox as it is against smallpox, doing research with cell lines (in vitro).
"To further understand the antipoxvirus activity associated with S. purpurea, we decided to analyze the capability of S. purpurea to prevent the replication of more virulent members of the Orthopoxvirus genus, namely monkeypox virus (MPXV) and variola virus (VARV). Cells were mock-infected or infected with MPXV and subsequently left untreated or treated with S. purpurea or carrier at the times indicated. Western blots for the presence of the MPXV-F3L protein (ortholog of the VACV-E3L protein) were performed to determine if a successful MPXV infection had occurred. When treated with the extract at 0 or 15 minutes post infection, S. purpurea treatment prevented the accumulation of the MPXV-F3L protein, whereas high levels of MPXV-F3L were detected in the both the untreated and carrier treated cells (Fig. 4a). A similar assay was performed with VARV where cells were mock-infected or infected with VARV and treated with S. purpurea or carrier at the dosages indicated (Fig. 4b). Western blots for the presence of the VARV E3L protein indicated a concentration dependent inhibition in the accumulation of the VARV-E3L protein in S. purpurea treated infections. In addition, we also determined that S. purpurea treatment effectively inhibited rabbitpox virus early protein accumulation (data not shown)."
"Next we assayed for the ability of VACV to replicate in cells under single-cycle conditions, treated once or every six hours, with S. purpurea extract. Treatment with S. purpurea began immediately following VACV infection and viral titers were determined every six hours. S. purpurea treatment resulted in a dramatic decrease in VACV replication, when compared to the untreated cells (Fig. 1b). A single treatment of S. purpurea, caused a 100–1000 fold reduction in VACV replication throughout the course of the infection, however some viral replication was still observed. In cells treated with fresh extract every six hours, a 10,000-fold decrease in VACV replication was observed. Multiple treatments with S. purpurea completely abolished VACV replication since titers did not increase over the course of the infection."
"In this study, we were able to demonstrate that S. purpurea specifically affected early viral transcription, the first antiviral agent to be characterized that targets poxviruses at this point in the replication cycle (Fig. 5). Although solely based on in vitro studies, our work supports the potential of S. purpurea as an additional treatment for poxvirus infections, either individually or in combination with other known antivirals."
In Vitro Characterization of a Nineteenth-Century Therapy for Smallpox
"In the nineteenth century, smallpox ravaged through the United States and Canada. At this time, a botanical preparation, derived from the carnivorous plant Sarracenia purpurea, was proclaimed as being a successful therapy for smallpox infections. The work described characterizes the antipoxvirus activity associated with this botanical extract against vaccinia virus, monkeypox virus and variola virus, the causative agent of smallpox. Our work demonstrates the in vitro characterization of Sarracenia purpurea as the first effective inhibitor of poxvirus replication at the level of early viral transcription. With the renewed threat of poxvirus-related infections, our results indicate Sarracenia purpurea may act as another defensive measure against Orthopoxvirus infections."
"In the late 1800's, the Micmac Indians of Nova Scotia proclaimed the existence of a botanical-based remedy for smallpox. During this time, Herbert Miles, the Assistant Surgeon to the Royal Artillery, reported that during an outbreak of smallpox “an old squaw going amongst them, and treating the cases with (a botanical) infusion…was so successful as to cure every case”. This botanical infusion was later described as being derived from the carnivorous plant, Sarracenia purpurea [1], [2].
In 1892, Charles Millspaugh described that the Native Americans of eastern North America used S. purpurea as a poultice against smallpox and it provided “the greatest remedy known for the dreadful scourge” [3]. C.G. Logie, Surgeon-Major of the Royal Horse Guards, treated variola-infected men in his regiment and found that S. purpurea “seemed to arrest the development of the pustules, killing, as it were, the virus from within, thereby changing the character of the disease and doing away with the cause of pitting” [4]. However, the putative medicinal properties of S. purpurea have been largely forgotten."
The authors of this article found that this remedy is as effective against Monkeypox as it is against smallpox, doing research with cell lines (in vitro).
"To further understand the antipoxvirus activity associated with S. purpurea, we decided to analyze the capability of S. purpurea to prevent the replication of more virulent members of the Orthopoxvirus genus, namely monkeypox virus (MPXV) and variola virus (VARV). Cells were mock-infected or infected with MPXV and subsequently left untreated or treated with S. purpurea or carrier at the times indicated. Western blots for the presence of the MPXV-F3L protein (ortholog of the VACV-E3L protein) were performed to determine if a successful MPXV infection had occurred. When treated with the extract at 0 or 15 minutes post infection, S. purpurea treatment prevented the accumulation of the MPXV-F3L protein, whereas high levels of MPXV-F3L were detected in the both the untreated and carrier treated cells (Fig. 4a). A similar assay was performed with VARV where cells were mock-infected or infected with VARV and treated with S. purpurea or carrier at the dosages indicated (Fig. 4b). Western blots for the presence of the VARV E3L protein indicated a concentration dependent inhibition in the accumulation of the VARV-E3L protein in S. purpurea treated infections. In addition, we also determined that S. purpurea treatment effectively inhibited rabbitpox virus early protein accumulation (data not shown)."
"Next we assayed for the ability of VACV to replicate in cells under single-cycle conditions, treated once or every six hours, with S. purpurea extract. Treatment with S. purpurea began immediately following VACV infection and viral titers were determined every six hours. S. purpurea treatment resulted in a dramatic decrease in VACV replication, when compared to the untreated cells (Fig. 1b). A single treatment of S. purpurea, caused a 100–1000 fold reduction in VACV replication throughout the course of the infection, however some viral replication was still observed. In cells treated with fresh extract every six hours, a 10,000-fold decrease in VACV replication was observed. Multiple treatments with S. purpurea completely abolished VACV replication since titers did not increase over the course of the infection."
"In this study, we were able to demonstrate that S. purpurea specifically affected early viral transcription, the first antiviral agent to be characterized that targets poxviruses at this point in the replication cycle (Fig. 5). Although solely based on in vitro studies, our work supports the potential of S. purpurea as an additional treatment for poxvirus infections, either individually or in combination with other known antivirals."
bw
Fringe Ranger
Thanks, good job!
helen
Panic Sex Lady
One of the gay fetish sites says this is a good time to wear latex.Covid and now Monkey Pox......I guess this is the only way to go out in public safely!
Suit up everyone!
psychgirl
Has No Life - Lives on TB
Interesting! I’ll look up jewel weed
phloydius
Veteran Member
Some of the interesting notes about Monkeypox. Way more in the PDF at the link:
-------------
DHS Science and Technology Directorate
July 2022
-------------
DHS Science and Technology Directorate
July 2022
- Early presentation consists of fever, fatigue, headache, backache, mild to severe pulmonary lesions, anorexia, dyspnea, conjunctivitis, nasal discharge, swollen lymph nodes, chills and/or sweats, sore throat, cough, and shortness of breath.
- Rash presents within 1-4 days of onset of symptoms and lasts from 2-4 weeks. Rash is typically confined to the trunk but may appear on the palms and soles of feet. Lesions can develop on mucous membranes, in the mouth, on the tongue, and on the genitalia.
- Transmission of MPXV occurs when a person comes into contact with the virus from an animal, human, or materials contaminated with the virus. The virus may enter the body through broken skin, the respiratory tract, or other mucous membranes such as the rectum, eyes, genitals and oral cavity.
- Human-to-human transmission is thought to occur primarily through respiratory droplets, direct contact with body fluids or lesion material, and indirect contact with lesion material via contaminated fomites.
- Rates of droplet transmission in this outbreak do not appear to be different from prior outbreaks.
- The interval between exposure and the development of symptoms ranges from 1-31 days, with 7-17 days being the typical range.
- Humans can be contagious before a visible rash appears and can continue shedding the virus weeks after symptoms have dissipated.
- Vaccination with smallpox vaccine (vaccinia virus) is reported to provide protection against 85% of MPXV infections. CDC recommends revaccination after 3 years for individuals with likely exposure.
- MPXV is very stable in the environment. These viruses can be stable for days to weeks under some circumstances.
- MPXV can survive in scabs for months to years.
- MPXV is resistant to desiccation in hot and cold environments.
- MPXV may be stable for days to weeks in water, soil, and on refrigerated food.
- Poxviruses are known to remain infectious in the scabs of patients for months to years, and viral DNA present in lesion material is stable for a long period of time if kept in a relatively dark, cool environment.
- Poxviruses are stable for days to weeks in storm water and soil, lasting longer at cold temperatures.
- After 14 days of storage at 4°C, MPXV was detected via PCR on food. Under the same conditions and methods, MPXV was also observed on gauze.
- MPXV-contaminated material including clothes, paper, and dust may remain contagious for years if not disinfected.
- After 6 months of storage of infected tissue culture fluid at 4°C, the infectivity titer of stocks remained unchanged from the original.
- For clinicians, PPE should be donned before entering the patient’s room and used for all patient contact. All PPE should be disposed of prior to leaving the isolation room where the patient is admitted. Optimal PPE include disposable gown and gloves, NIOSH-certified N95 (or comparable) filtering disposable respirator, and face shield or goggles.
Cascadians
Leska Emerald Adams
GOOD NEWS !!! Really liberating good news! Easy natural CURE FOR POXES !!!
New methylene blue derivatives suggest novel anti-orthopoxviral strategies
"Abstract
Decades after the eradication of smallpox and the discontinuation of routine smallpox vaccination, over half of the world's population is immunologically naïve to variola virus and other orthopoxviruses (OPXVs). Even in those previously vaccinated against smallpox, protective immunity wanes over time. As such, there is a concomitant increase in the incidence of human OPXV infections worldwide. To identify novel antiviral compounds with potent anti-OPXV potential, we characterized the inhibitory activity of PAV-866 and other methylene blue derivatives against the prototypic poxvirus, vaccinia virus (VACV). These compounds inactivated virions prior to infection and consequently inhibited viral binding, fusion and entry. The compounds exhibited strong virucidal activity at non-cytotoxic concentrations, and inhibited VACV infection when added before, during or after viral adsorption. The compounds were effective against other OPXVs including monkeypox virus, cowpox virus and the newly identified Akhmeta virus. Altogether, these findings reveal a novel mode of inhibition that has not previously been demonstrated for small molecule compounds against VACV. Additional studies are in progress to determine the in vivo efficacy of these compounds against OPXVs and further characterize the anti-viral effects of these derivatives.
Keywords: Antiviral; Methylene blue; Novel inhibitor; PAV-866; Poxviruses; Vaccinia virus."
Methylene Blue
pubmed.ncbi.nlm.nih.gov
And Methylene Blue also cures many other health problems.
There are books written about Methylene Blue and how many different health conditions it helps.
Here is a list of scientific articles detailing how Methylene Blue cures:
pubmed.ncbi.nlm.nih.gov
You can buy human grade Methylene Blue on Amazon and in stores.
Methylene Blue cures mitochondrial dysfunction and cures brain fog.
Methylene Blue cures all the poxes !!!!! Cures monkeypox.
New methylene blue derivatives suggest novel anti-orthopoxviral strategies
"Abstract
Decades after the eradication of smallpox and the discontinuation of routine smallpox vaccination, over half of the world's population is immunologically naïve to variola virus and other orthopoxviruses (OPXVs). Even in those previously vaccinated against smallpox, protective immunity wanes over time. As such, there is a concomitant increase in the incidence of human OPXV infections worldwide. To identify novel antiviral compounds with potent anti-OPXV potential, we characterized the inhibitory activity of PAV-866 and other methylene blue derivatives against the prototypic poxvirus, vaccinia virus (VACV). These compounds inactivated virions prior to infection and consequently inhibited viral binding, fusion and entry. The compounds exhibited strong virucidal activity at non-cytotoxic concentrations, and inhibited VACV infection when added before, during or after viral adsorption. The compounds were effective against other OPXVs including monkeypox virus, cowpox virus and the newly identified Akhmeta virus. Altogether, these findings reveal a novel mode of inhibition that has not previously been demonstrated for small molecule compounds against VACV. Additional studies are in progress to determine the in vivo efficacy of these compounds against OPXVs and further characterize the anti-viral effects of these derivatives.
Keywords: Antiviral; Methylene blue; Novel inhibitor; PAV-866; Poxviruses; Vaccinia virus."
Methylene Blue
New methylene blue derivatives suggest novel anti-orthopoxviral strategies - PubMed
Decades after the eradication of smallpox and the discontinuation of routine smallpox vaccination, over half of the world's population is immunologically naïve to variola virus and other orthopoxviruses (OPXVs). Even in those previously vaccinated against smallpox, protective immunity wanes over...
pubmed.ncbi.nlm.nih.gov
And Methylene Blue also cures many other health problems.
There are books written about Methylene Blue and how many different health conditions it helps.
Here is a list of scientific articles detailing how Methylene Blue cures:
methylene blue - Search Results - PubMed
methylene blue - Search Results - PubMed
pubmed.ncbi.nlm.nih.gov
You can buy human grade Methylene Blue on Amazon and in stores.
Methylene Blue cures mitochondrial dysfunction and cures brain fog.
Methylene Blue cures all the poxes !!!!! Cures monkeypox.
bw
Fringe Ranger
From the article, it's not methylene blue but some chemical made from it called PAV-866. If you're not a biochemist with a lab, buying methylene blue doesn't appear helpful.
bw
Fringe Ranger
I have no idea if this can be relied upon or not. We can't translate the strength to anything meaningful. We won't know until we get feedback from people who are trying the currently available preparations on the current disease.
All that aside, when this bug takes off the sarracenia is going to vanish overnight. So if you want to try it, last week was a good time to order.
phloydius
Veteran Member
All information is "as best of my knowledge" and is based on the resources that are being posted the the main Monkeypox Thread. I am working on a list of F.A.Q's for this thread:
F.A.Q.'s
What are the symptoms?
See Post #37
www.timebomb2000.com
What can I buy to help prevent, treat, and deal with Monkeypox?
See Post #2
www.timebomb2000.com
-- Does the smallpox vaccine from childhood prevent Monkeypox? --
Yes & No. The studies posted in the "Monkeypox - Consolidated Thread" indicate that there is a benefit of having the smallpox vaccine from decades ago. The information does not say that it will prevent a Monkeypox infection in all cases, but does say that will will prevent Monkeypox infections in some cases and reduce the severity in others. The more that that has passed since the smallpox vaccine the less protection it provides. The CDC & WHO recommend that if someone with a smallpox vaccine from over 3-5 years ago contracts Monkeypox, they should get another vaccine withing 4 days of the date of exposure (which is before symptoms start showing). Getting a vaccine after symptoms appear is unlikely to reduce symptoms. Getting a vaccine 14 days after exposure is more likely to make the infection more severe.
-- How does the Monkeypox virus infect someone? --
1. Thru the mucous membranes in the mouth, nose, eyes, genitals, and rectum.
2. Thru Broken skin, including micro cracks that are invisible to the human eye that are very common on the fingers and hands.
3. Thru the lungs by breathing.
4. Eating infected food or drink.
-- How long does the Monkeypox virus live on surfaces? --
A long time, but the exact time is not well known: For at least several days but more likely for weeks.
Monkeypox can survive in dried scabs (that fall off) for years.
Monkeypox can survive in water, soil and refrigerated food for weeks.
The colder the temperature, the longer the Monkeypox virus can live.
Monkeypox can survive for years on porous items (like cloth, bedding, and paper).
F.A.Q.'s
What are the symptoms?
See Post #37
MNKYPOX - MonkeyPox Treatment & Prevention [No Politics / No Reporting / No News]
MonkeyPox Treatments / Planning / Prevention [No Politics / No Reporting / No News] Starting this thread for the ideas for treating MonkeyPox, per request by SouthernBreeze. What is this thread for? Ideas for the treatment of Monkeypox. Items for first aid kits, emergency kits, SHTF kits...
What can I buy to help prevent, treat, and deal with Monkeypox?
See Post #2
MNKYPOX - MonkeyPox Treatment & Prevention [No Politics / No Reporting / No News]
MonkeyPox Treatments / Planning / Prevention [No Politics / No Reporting / No News] Starting this thread for the ideas for treating MonkeyPox, per request by SouthernBreeze. What is this thread for? Ideas for the treatment of Monkeypox. Items for first aid kits, emergency kits, SHTF kits...
-- Does the smallpox vaccine from childhood prevent Monkeypox? --
Yes & No. The studies posted in the "Monkeypox - Consolidated Thread" indicate that there is a benefit of having the smallpox vaccine from decades ago. The information does not say that it will prevent a Monkeypox infection in all cases, but does say that will will prevent Monkeypox infections in some cases and reduce the severity in others. The more that that has passed since the smallpox vaccine the less protection it provides. The CDC & WHO recommend that if someone with a smallpox vaccine from over 3-5 years ago contracts Monkeypox, they should get another vaccine withing 4 days of the date of exposure (which is before symptoms start showing). Getting a vaccine after symptoms appear is unlikely to reduce symptoms. Getting a vaccine 14 days after exposure is more likely to make the infection more severe.
-- How does the Monkeypox virus infect someone? --
1. Thru the mucous membranes in the mouth, nose, eyes, genitals, and rectum.
2. Thru Broken skin, including micro cracks that are invisible to the human eye that are very common on the fingers and hands.
3. Thru the lungs by breathing.
4. Eating infected food or drink.
-- How long does the Monkeypox virus live on surfaces? --
A long time, but the exact time is not well known: For at least several days but more likely for weeks.
Monkeypox can survive in dried scabs (that fall off) for years.
Monkeypox can survive in water, soil and refrigerated food for weeks.
The colder the temperature, the longer the Monkeypox virus can live.
Monkeypox can survive for years on porous items (like cloth, bedding, and paper).
bw
Fringe Ranger
Need an emoji for "like the post, hate the info".
amazon
Veteran Member
Before it was OTC Voltaren was only "apporoved" for shingles with some insurance plans. Could Voltaren be beneficial in your opinion? (This would be before any pustules open.)
SouthernBreeze
Has No Life - Lives on TB
Isn't OTC Voltaren an NSAID?
phloydius
Veteran Member
I have used Voltaren for about 10 years IIRC. It works great on joint pain and muscle pain, which is what I have used it for. I know they say it is approved for shingles, but I used it on various itches (from things like mosquito bites that became enlarged) but it had little to no effect. The itches I tried to use it on were all histamine reactions, which is likely why it won't help (and why Benadryl probably won't help on Monkeypox sores). I have tried Voltaren on "nerve" pain like itching & burning in the feet and legs caused by damage to the nerve in the back - and it did not help there either.
Maybe Rondaben, or someone that knows, can let us know if the rash cause by shingles is biologically similar reaction to the rash & sores that are caused by Monkeypox? Or if anyone that has had shingles might let us know if Voltaren gel helped them.
Voltaren is a NSAID, stronger than ibuprofen.
SouthernBreeze
Has No Life - Lives on TB
Yeah. The Voltaren I have is used for arthritis pain, but hasn't worked for anything else for me. I've never tried it on nerve pain, though. I may do that next time my sciatica acts up to see how it works.
Would be ok as anti-inflammatory. Just put it on gently. It's not really meant for the face however