I know they are dangerous.I have a 17 cal air rifle where the projectile will completely pass through the body of a gopher which is 1.5 to 2 inches of meat. If a human is hit, it should do the same and a good shot could penetrate a vital organ. Point being they are dangerous, but I'd never consider using it in a self defense situation, unless that's all I had.
I shot an adult raccoon in my corn crib one night with my Sheridan. It was climbing the rafters, it hit the raccoon in the neck.
Hit an artery, in slow motion the raccoon relaxed and fell to the concrete floor.
Yes, a lucking shot.