CORONA HIV/Coronavirus

[Melodi]

This is also on the long thread but I thought this was so important that people might want to read it and not have it lost in the shuffle, - this is Nightwolf's response after going and actually reading that PDF that is supposedly linking HIV to the new Coronavirus when in reality it is based on HIV drugs (anti-virals) being used to treat the disease (its a virus). In the same way that these drugs are now being used to treat hepatitis C and other viral conditions - Melodi (aka Disastercat)

HIV/Coronavirus:

This is actually Nightwolf writing, not Disastercat; she asked me to check it out because it's kind of above her pay grade.

A drug combination (lopinavir/itonavir) originally developed and chiefly used for treating HIV is being used (in a sort of "Hail Mary pass" way, I suspect) hopefully to treat the 2019 NoCoV in China.

This does not mean, imply, or even faintly suggest that there is any element of the HIV genome in the Wuhu Flu. Several drugs developed for treating HIV are currently well-tested and considered effective, for instance, in treating plain aul' natural hepatitis C.

The Wuhu Flu is (like the majority of human-pathogenic viruses) an RNA virus; it is not a retrovirus, but it is an RNA virus, and therefore it would not surprise me if some anti-HIV drugs turned out to be as effective against it as they appear to be in the evolving treatment of hep C.

This does not, of course, mean that I think that the Wuhu Flu is necessarily natural. I have been kind of amused by the efforts made from publications from the Lancet to the Sun not to actually stand up, point at China, and scream, "Liar, liar, pants on fire" about the whole "where did it come from?" issue (the Lancet article was the most entertaining to those who read Carefully Professional Doctorese). But no, no reason to think HIV was tossed into the same pot as maybe a couple of other coronaviruses...


UNLESS Blizzard has a reason, disclosable or not, to think otherwise. He is the guy to whom I would listen in a questionable area on this.

Incidentally, on that topic...Blizzard mentioned domestic cats. No one else that I could find has ever mentioned domestic cats...except for a brief mention ca. 2004 (SARS) in which a couple of researchers observed that the SARS virus could be propagated in cats and ferrets; it killed some of the ferrets, but left the cats unharmed, though propagating successfully. The researchers concluded that the common house cat would make an ideal subject for further investigation of the SARS coronavirus. And there the topic went silent.

Would anyone care to guess the country of origin suggested by those researchers' names? (Does anyone even feel that they *have* to guess?)

If the disease becomes an issue in Ireland, I know a number of indoor/outdoor cats who will be crabby full-time locked up cats for the duration...

 

[adgal]

Thank you - that really was a frightening rumor.

 

[Dozdoats]

Thanks, Nightwolf.

 

[Plain Jane]

That's a relief, Nightwolf! Thanks.

 

[Grock]

Coronavirus Contains "HIV Insertions", Stoking Fears Over Artificially Created Bioweapon
by Tyler Durden
Fri, 01/31/2020 - 17:35


Over the past few days, the mainstream press has vigorously pushed back against a theory about the origins of the coronavirus that has now infected as many as 70,000+ people in Wuhan alone (depending on whom you believe). The theory is that China obtained the coronavirus via a Canadian research program, and started molding it into a bioweapon at the Institute of Virology in Wuhan. Politifact pointed the finger at Zero Hedge, in particular, though the story was widely shared across independent-leaning media.
The theory is that the virus, which was developed by infectious disease experts to function as a bio-weapon, originated in the Wuhan-based lab of Dr. Peng Zhou, China's preeminent researcher of bat immune systems, specifically in how their immune systems adapt to the presence of viruses like coronavirus and other destructive viruses. Somehow, the virus escaped from the lab, and the Hunan fish market where the virus supposedly originated is merely a ruse.
Now, a respected epidemiologist who recently caught flack for claiming in a twitter threat that the virus appeared to be much more contagious than initially believed is pointing out irregularities in the virus's genome that suggests it might have been genetically engineered for the purposes of a weapon, and not just any weapon but the deadliest one of all.
In "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag", Indian researchers are baffled by segments of the virus's RNA that have no relation to other coronaviruses like SARS, and instead appear to be closer to HIV. The virus even responds to treatment by HIV medications.



For those pressed for time, here are the key findings from the paper, which first focuses on the unique nature of 2019-nCoV, and then observe four amino acid sequences in the Wuhan Coronavirus which are homologous to amino acid sequences in HIV1:

Our phylogentic tree of full-length coronaviruses suggests that 2019-nCoV is closely related to SARS CoV [Fig1].

In addition, other recent studies have linked the 2019-nCoV to SARS CoV. We therefore compared the spike glycoprotein sequences of the 2019-nCoV to that of the SARS CoV (NCBI Accession number: AY390556.1). On careful examination of the sequence alignment we found that the 2019- nCoV spike glycoprotein contains 4 insertions [Fig.2]. To further investigate if these inserts are present in any other corona virus, we performed a multiple sequence alignment of the spike glycoprotein amino acid sequences of all available coronaviruses (n=55) [refer Table S.File1] in NCBI refseq (ncbi.nlm.nih.gov) this includes one sequence of 2019-nCoV[Fig.S1]. We found that these 4 insertions [inserts 1, 2, 3 and 4] are unique to 2019-nCoV and are not present in other coronaviruses analyzed. Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses . Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses (Zhou et al., 2020).
We then translated the aligned genome and found that these inserts are present in all Wuhan 2019-nCoV viruses except the 2019-nCoV virus of Bat as a host [Fig.S4]. Intrigued by the 4 highly conserved inserts unique to 2019-nCoV we wanted to understand their origin. For this purpose, we used the 2019-nCoV local alignment with each insert as query against all virus genomes and considered hits with 100% sequence coverage. Surprisingly, each of the four inserts aligned with short segments of the Human immunodeficiency Virus-1 (HIV-1) proteins. The amino acid positions of the inserts in 2019-nCoV and the corresponding residues in HIV-1 gp120 and HIV-1 Gag are shown in Table 1.

The first 3 inserts (insert 1,2 and 3) aligned to short segments of amino acid residues in HIV-1 gp120. The insert 4 aligned to HIV-1 Gag. The insert 1 (6 amino acid residues) and insert 2 (6 amino acid residues) in the spike glycoprotein of 2019-nCoV are 100% identical to the residues mapped to HIV-1 gp120. The insert 3 (12 amino acid residues) in 2019- nCoV maps to HIV-1 gp120 with gaps [see Table 1]. The insert 4 (8 amino acid residues) maps to HIV-1 Gag with gaps.

Why do the authors think the virus may be man-made? Because when looking at the above insertions which are not present in any of the closest coronavirus families, "it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time." Instead, they can be found in cell identification and membrane binding proteins located in the HIV genome.

Since the S protein of 2019-nCoV shares closest ancestry with SARS GZ02, the sequence coding for spike proteins of these two viruses were compared using MultiAlin software. We found four new insertions in the protein of 2019-nCoV- “GTNGTKR” (IS1), “HKNNKS” (IS2), “GDSSSG” (IS3) and “QTNSPRRA” (IS4) (Figure 2). To our surprise, these sequence insertions were not only absent in S protein of SARS but were also not observed in any other member of the Coronaviridae family (Supplementary figure). This is startling as it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time.
The insertions were observed to be present in all the genomic sequences of 2019-nCoV virus available from the recent clinical isolates. To know the source of these insertions in 2019-nCoV a local alignment was done with BLASTp using these insertions as query with all virus genome. Unexpectedly, all the insertions got aligned with Human immunodeficiency Virus-1 (HIV-1). Further analysis revealed that aligned sequences of HIV-1 with 2019-nCoV were derived from surface glycoprotein gp120 (amino acid sequence positions: 404-409, 462-467, 136-150) and from Gag protein (366-384 amino acid) (Table 1). Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4.This binding induces structural rearrangements in GP120, creating a high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5.

A good recap of the findings was provided by Dr. Feigl-Ding, who started his explanatory thread by pointing out that the transmission rate outside China has surpassed the rate inside China.

Much more:

Zerohedge

ZeroHedge - On a long enough timeline, the survival rate for everyone drops to zero

www.zerohedge.com

 

[adgal]

Coronavirus Contains "HIV Insertions", Stoking Fears Over Artificially Created Bioweapon
by Tyler Durden
Fri, 01/31/2020 - 17:35


Over the past few days, the mainstream press has vigorously pushed back against a theory about the origins of the coronavirus that has now infected as many as 70,000+ people in Wuhan alone (depending on whom you believe). The theory is that China obtained the coronavirus via a Canadian research program, and started molding it into a bioweapon at the Institute of Virology in Wuhan. Politifact pointed the finger at Zero Hedge, in particular, though the story was widely shared across independent-leaning media.
The theory is that the virus, which was developed by infectious disease experts to function as a bio-weapon, originated in the Wuhan-based lab of Dr. Peng Zhou, China's preeminent researcher of bat immune systems, specifically in how their immune systems adapt to the presence of viruses like coronavirus and other destructive viruses. Somehow, the virus escaped from the lab, and the Hunan fish market where the virus supposedly originated is merely a ruse.
Now, a respected epidemiologist who recently caught flack for claiming in a twitter threat that the virus appeared to be much more contagious than initially believed is pointing out irregularities in the virus's genome that suggests it might have been genetically engineered for the purposes of a weapon, and not just any weapon but the deadliest one of all.
In "Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag", Indian researchers are baffled by segments of the virus's RNA that have no relation to other coronaviruses like SARS, and instead appear to be closer to HIV. The virus even responds to treatment by HIV medications.



For those pressed for time, here are the key findings from the paper, which first focuses on the unique nature of 2019-nCoV, and then observe four amino acid sequences in the Wuhan Coronavirus which are homologous to amino acid sequences in HIV1:

Why do the authors think the virus may be man-made? Because when looking at the above insertions which are not present in any of the closest coronavirus families, "it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time." Instead, they can be found in cell identification and membrane binding proteins located in the HIV genome.

A good recap of the findings was provided by Dr. Feigl-Ding, who started his explanatory thread by pointing out that the transmission rate outside China has surpassed the rate inside China.

Much more:

Zerohedge

ZeroHedge - On a long enough timeline, the survival rate for everyone drops to zero

www.zerohedge.com

Thanks for sharing this Grock! I thought this was what Nightwolf was initially replying to - but perhaps not. I'm not feeling as relieved as I was a few minutes ago.

 

[Grock]

Dr. Eric Feigl-Ding @DrEricDing




3) “An estimated 75815 individuals have been infected in Wuhan” —> this is substantially higher than current reports or ~10k reports by China

media. (75k estimate from above Lancet article)

Dr. Eric Feigl-Ding @DrEricDing

4) ...”On the present trajectory, 2019-nCoV could be about to become a global epidemic in the absence of mitigation...substantial, even draconian measures that limit population mobility should be seriously and immediately considered in affected areas...”

248

11:37 AM - Jan 31, 2020












Dr. Eric Feigl-Ding

@DrEricDing

16. UPDATE ON

GENOME

: a very intriguing new paper investigating the aforementioned mystery middle segment w/ “S” spike protein: likely origin from HIV. “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag” from https://biorxiv.org/content/10.1101/2020.01.30.927871v1




1:04 PM · Jan 31, 2020·Twitter for iPhone
https://twitter.com/DrEricDing/status/1223305946723704832/retweets
https://twitter.com/DrEricDing


Replying to
@DrEricDing
17. ...WHOA- the authors said the finding was “Unexpectedly” related to genes from HIV virus. Notably there were 4 gene insertions (see figure in above post #16). And so, which HIV gene proteins were found in the new #coronarvirus? Gag protein and Gp120- key HIV proteins...














18. Notably, in

S

, authors say for HIV

insertions: “Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4”










Dr. Eric Feigl-Ding

@DrEricDing

·
5h

19. Again, these are new express published findings and not peer reviewed yet. Let’s not draw conclusions yet. But evidence suggest that 2 different HIV genes

are present in the #coronarvirus S gene region (that didn’t map to any other coronavirus, according to other studies).










Dr. Eric Feigl-Ding

@DrEricDing

·
5h

20. Further the authors add that “This indicates that these insertions have been preferably acquired by the 2019-nCoV, providing it with additional survival and infectivity advantage. Delving deeper we found that these insertions were similar to HIV-1.”











Dr. Eric Feigl-Ding

@DrEricDing

·
5h

21. Paper piles on: “these

insertions are present at binding site of 2019-nCoV. Due to presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors.”












Dr. Eric Feigl-Ding

@DrEricDing

·
5h

22. The authors dunked this final conclusion: “This uncanny similarity of novel inserts in the 2019- nCoV spike protein to HIV-1 gp120 and Gag is unlikely to be fortuitous”. Wow, they sure just went straight there!

What a bold paper... I don’t know what to say

 

[Grock]

Buckle up.
We're going in.

 

[Telescope Steve]

I am not an emotional person in the slightest. My dear wife thinks of me as an autistic cross between Mr Spock and Mr Data. And she is right to see me this way.

At this point all I can do is cry out in my micro man cave or alone on my lonely dirt road, "F...., F...., F..., are you kidding me? What the F!"

I don't have the vocabulary to vocalize my feelings.

All I can think is that we had be better be ready to go and meet our maker, because the only real option for us in the VERY near future is to shelter in place. And that will be a HUGE stretch for my budget it I have to stop getting paid to commute to work where they pay a large share of my medical insurance.

I have never said this before but, OMFG!

 

[adgal]

I am not an emotional person in the slightest. My dear wife thinks of me as an autistic cross between Mr Spock and Mr Data. And she is right to see me this way.

At this point all I can do is cry out in my micro man cave or alone on my lonely dirt road, "F...., F...., F..., are you kidding me? What the F!"

I don't have the vocabulary to vocalize my feelings.

All I can think is that we had be better be ready to go and meet our maker, because the only real option for us in the VERY near future is to shelter in place. And that will be a HUGE stretch for my budget it I have to stop getting paid to commute to work where they pay a large share of my medical insurance.

I have never said this before but, OMFG!

If -IF - it gets that bad we will all be sheltering in place. The bankers, the credit card company folks, the mortgage companies - no one is going to be worried about your monthly bill. What you need to make sure is IF you do have to shelter in place, you have enough basic supplies to keep you and your family safe and healthy.

 

[homecanner1]

Its a bioweapon, a mulligan stew of the finest goodies like Bat, Civet, MERS Camel phlegm, recombined SARS and whatever else they could toss in the pot of lethality

The woman in her 60's who flew to Wuhan to care for her elderly father, returned to Chicago Jan 13th and her genome sequencing is showing at least *6 mutations* of this virus with 5 of them having two or more DNA chain portions testing positive for the Schenzhen strain.

She had a sick parent to tend to and likely was not gallivanting in markets or out dining in restaurants and still managed to become exposed, likely from her father. She in turn infected her husband and those are the two Chicago cases so far.

This is the Wuhan animal market taken earlier in the summer, cats, rats, burmese pythons, all readily available for potion makers

View: https://www.liveleak.com/view?t=CJwfc_1580239584


is anyone surprised that multiple strains merged and married?

the culture is rife with nefarium now., food and drink tampering was promoted thru the whole series of Potter. The radical left were encouraged and indoctrinated in this filth of poisoning others

"...Snape gleefully threatened to slip a few drops of Veritaserum into Harry's evening pumpkin juice..."

They were promoting this as children's literature in order to hide it but in reality it was for adult warlocks and covens
slipped into a "children's story " to secretly softpedal it . An ye harm none? This is not harmless. Its like Haitian voodoo.

Draught of Living Death

The Draught of Living Death is a very powerful sleeping potion which is mentioned by Professor Snape in the first ever potions class. This potion cannot be made on Pottermore, although numerous ingredients used in its brewing process can be found, suggesting it might be available at a later...

pottermore.fandom.com

Ingredients

• Powdered Root of Asphodel.
• Infusion of Wormwood.
• Valerian Sprigs.
• Sloth Brain. <------ we shouldn't be eating sloths
• Juice of a Sopophorous Bean.
• Wormwood.

you can defend it all you want, build themepark temples to it and decorate your Christmas tree with slytherin ornaments

but it does not negate the fact that this was promoted, endorsed, celebrated, venerated, elevated across the world

and now you understand why Christian Africa rejected this, they have all they can deal with desperate, superstitious people eating batmeat and raping virgins to cure AIDS, killing albino black children as 'demons'.

This is real and it requires digging up corpses. In this instance they used a child they exhumed from a graveyard.

From the Archives: The Secrets of Haiti’s Living Dead

A Harvard botanist investigates mystic potions, voodoo rites, and the making of zombies.

www.harvardmagazine.com

"....The powder, which Davis keeps in a small vial, looks like dry black dirt. It contains parts of toads, sea worms, lizards, tarantulas, and human bones. (To obtain the last ingredient, he and Pierre unearthed a child’s grave on a nocturnal trip to the cemetery.) The poison is rubbed into the victim’s skin. Within hours he begins to feel nauseated and has difficulty breathing. A pins-and-needles sensation afflicts his arms and legs, then progresses to the whole body. The subject becomes paralyzed; his lips turn blue for lack of oxygen. Quickly—sometimes within six hours—his metabolism is lowered to a level almost indistinguishable from death...."

The culture has lost its mind, perhaps proteins were labinserted in some crazed desperate attempt to level the playing field & give everyone feline leukemia meets batcough. Sadly, those immune compromised may be the first to perish. Backfired.

I am hearing this thing is going hard after Asian men aged 40-65 as they have more ACE 2 receptors. So that was custom tweaking to achieve that effect. Probably Beijing desperately trying to cull its own rampant over population, too many men, imbalance from killing off so many female fetuses, a whole generation of wives/mothers were lost by that atrocity.

It is a sad commentary on our world that sitcoms, films, drama series, young adult fiction, novels all revolve around the idiocy of Vampirism from American Horror Story to Twilight to True Blood and others. Consuming human blood is an abomination. It is unclean to engage in this behavior or making spells with lizards, toads, seaworms, tarantulas, batwings, dug up corpses and spiritcooking dinner parties. Publishers are reckless to have indulged this madness for the last 20 yrs.

I foresee a day when those books all get pulled from school library shelves and burnt in bonfires after the final death tolls.

I hated those books from day one and forbid them in my house knowing exactly what they were promoting in graduated steps of increasing levels of toxicity as the students advanced in their sorcery. Now everyone has to learn it the hard way.

Instagram witches pages are full of apothecary bottles they proudly concoct and share images of what they plan to use on us, unrepentant Trump supporters. Get it through your heads that this is not idle boasting on their part, they believe this crap. And you can make people very sick with even minute amounts of this used in eyedroppers into your smoothie or your raw salsa and chips. Hmmm?

An ye harm none. So they say.

 

[Doc1]

I am not an emotional person in the slightest. My dear wife thinks of me as an autistic cross between Mr Spock and Mr Data. And she is right to see me this way.

At this point all I can do is cry out in my micro man cave or alone on my lonely dirt road, "F...., F...., F..., are you kidding me? What the F!"

I don't have the vocabulary to vocalize my feelings.

All I can think is that we had be better be ready to go and meet our maker, because the only real option for us in the VERY near future is to shelter in place. And that will be a HUGE stretch for my budget it I have to stop getting paid to commute to work where they pay a large share of my medical insurance.

I have never said this before but, OMFG!

Hey Steve, if it gets really sideways no one is going to be worrying about many bills. Medical insurance? What for? In overcrowded hospitals there won't be any room for you. Look at China now. Rent? Mortgage? No judges will be granting eviction orders or foreclosures and no deputies will be serving them.

What you are doing my friend is projecting your normal "today" worries onto a possible future where those concerns won't apply. If - and it's a huge if - this goes really bad going forward, your worries will be enough food and water to shelter in place and a weapon you're competent with to protect you and yours.

Best
Doc

 

[Hfcomms]

What Doc said. If it gets that bad everyone is in the same boat. It’s going to be a hard decision whether or not to go to work when the time comes and I’m thinking about that myself with many variables to consider.

 

[Freeholder]

Suspect a lot of companies which depend on product from China are going to be either slowing down, or shutting down within a few weeks. This will cause cascading failures as their businesses affect other businesses. Not sure just how bad things will actually get, but looking like this could be that black swan we’ve all been watching for.

Kathleen

 

[Quiet Man]

At this point all I can do is cry out in my micro man cave or alone on my lonely dirt road, "F...., F...., F..., are you kidding me? What the F!"

The foundation of my nature is definitely emotional, but I have spent a lifetime living and working in my intellect. It's easier for me to relate to the words of Doc1 and Hfcomms, but I appreciate your words because they curiously brought me to a moment of silence and into the present.

Perhaps you're just a little further ahead on the curve than most of the rest of us.

Best wishes for your peace and equanimity.

 

[Quiet Man]

Suspect a lot of companies which depend on product from China are going to be either slowing down, or shutting down within a few weeks.

As a hobby I play with electronics, and I have several items on order through AliExpress. It definitely looks like they are 'stuck'.

 

[zealotbat]

My conspiracy theory is they used Chinese DNA in the lab, targeted for race, tested on prisoners, released by Hong Konger type free thinking lab man..... f the shit up in China.....big middle finger to the CCP