FOOD Gene-edited tomatoes: British scientists create tomato with 'souped-up' vitamin D

Melodi

Disaster Cat
So why not just have people eat foods with some vitamin D like Salmon, Tuna, Eggs, and Mushrooms? Not to mention 15 minutes in the sun when it is there, before putting on the sunscreen? Can you say GMO's via the back door? Science still really doesn't know what will happen 10 generations (years) of plants down the line when even one gene is tampered with at a time, there have been cases where it affected other genes that did things like increasing the natural poisons in potatoes to a toxic level. I point out that tomatoes are Nightshades too, I think I just stick with heritage varieties and eat my egg yokes. What the UK government really wants is full GMOs which are not generally grown and must be labeled for human consumption in the EU (so people don't buy them).
Gene-edited tomatoes: British scientists create tomato with 'souped-up' vitamin D
The development comes in the same week the government will propose a change in the law that will make it easier to develop and sell gene-edited crops.

Tom Clarke

Science and technology editor @aTomClarke
Monday 23 May 2022 16:43, UK


UK scientists have used gene-editing technology to create a souped-up tomato containing as much vitamin D as two eggs or a serving of tuna.

The development comes in the same week the government will propose a change in the law that will make it easier to develop and sell gene-edited crops.

Scientists at the John Innes Centre in Norwich created the tomato by switching off one of its genes.
Tomatoes naturally produce lots of the chemical pre-cursor of vitamin D but the plants normally use this to make other biochemicals they need.

By deleting the gene that carries out this chemistry in the plant, the researchers boosted levels of the vitamin D precursor. Ordinary sunlight falling on the leaves and the fruit then turns the chemical into Vitamin D3.


"Forty percent of Europeans have vitamin D insufficiency and so do one billion people worldwide," said Professor Cathie Martin, who led the research published today in the journal Nature Plants.

"Tomatoes could be developed as a plant-based sustainable source of vitamin D3," she said.
 

dioptase

Veteran Member
Thank God for the Seed Saver org, and all the smaller seed companies selling heirloom and non-GMO seeds.

(Thread drift - MAYBE. I wasn't going to grow tomatoes this year because of the drought, and a couple other reasons. I told DH this, but apparently he forgot. The last two times he went to the farmers' market, he came back with tomatoes which were who-knows-what-cultivar, grown-who-knows-how-or-where. They look beautiful, but are like hard plastic, no taste, no ripening off the vine. GMOs? DH is very unhappy, wanting to know why he wasn't consulted in the grow-tomatoes-or-not decision. So now (since it's too late for ME to start seeds, unless maybe of a dwarf indeterminate Russian variety that I tried last year), I'm scrambling to find non-hybrid plants.)
 

Melodi

Disaster Cat
At least you get the info on the label.

No such labeling here in USA.

:(
And the UK is no longer in the EU, so they no longer have to provide labels.

Labels here are why the companies in the US spent billions stopping State or Federal mandates in the US. European sales of GMO foods dropped pretty much to next to nothing within a year. Today, even the really poor places like Bulgaria and Romania where cheap was the usual consumer concern have stopped selling all or most of them.

The average person doesn't know that animal feed is imported from the US and is GMO but does not have to be labeled - so anyone who eats meat gets some indirectly unless they only eat organic which is too expensive for most people

One reason the companies even in the US are switching to "name changes" like "Gene-Edited" or Assisted Biology is because they know eventually some labeling will be forced on them at some point and they want to confuse people as long as possible.
 

Melodi

Disaster Cat
you mean like curing god made diseases?stuff like that?
Diseases hurt people and their companion animals, curing them and treating them is the lessening of suffering.

Forcing a plant to express in ways that nature never intended (or you could just breed for it) or messing around with its genomics simply to produce a nutrient that is readily and naturally occurring in other foods is redundant It is also most likely a gateway to trying to convince people to allow other forms of genetic tampering whose main value is the ability to copywriter and make money from those seeds and to control the distribution and sale of the resulting plants.

There is no real need for a tomato that produces Vitamin D, the population of Europe can get their Vitamin D through already existing foods that I listed or they can take either a Cod Liver Oil Pill or a pill with vitamin D.

In the case of Vitamin D, modern medical advice could stop treating people like infants and explain that while too much time exposed to the sun can result in skin cancers, a small amount like 10 to 15 minutes a day is perfect for forming Vitamin D.

But it is much more profitable for big mega-corporations, that now own the majority of seed companies in the world, to create and genetically modify existing plants so they can patent them.

They are not doing this to cure diseases or make sure everyone has vitamin D, if that were true, they wouldn't need these tomatoes If the goal is to convince the public to eat genetically modified foods that only they can own and sell, it is a rather clever way to try to do it.
 

ShadowMan

Designated Grumpy Old Fart
Science still really doesn't know what will happen 10 generations (years) of plants down the line when even one gene is tampered with at a time, there have been cases where it affected other genes that did things like increasing the natural poisons in potatoes to a toxic levels.

EXACTLY!! When you work WITHIN nature instead of Frankinsteining it there are natural limits. I simply do not trust GMO anything. We are not good at playing GOD!! There are natural limits for good reasons. We don't have to understand those limits, rather just accept them and move on.

There is a reason that Jellyfish and lettuce don't and can't mate.
Reference: there was attempt years back to add jellyfish DNA into lettuce plants so that when the lettuce needed more water it would change color or something like that. Some things shouldn't be adulterated.
 

Melodi

Disaster Cat
In Asia, you can still buy kitties that were given a "glow fish" gene and they glow in the dark, thankfully the poor things seem otherwise healthy and have become something of a vanity product (I guess the trait either breeds true or there's a lab somewhere doing this, again in an unregulated part of Asia).

There's another issue in that nearly 90 to 95 percent (or more) of scientists who study enough to get jobs in the plant industry to have to work for the Giantantic Corporations that control most of the world's seeds. There are a few, mostly those who are good-hearted and have an independent source of income, who do the serious research on the actual outcomes of some of this stuff, but they have extreme problems getting it published because the big corporations also control the scientific journals to a large extent.

The "researchers" in the UK that work for those companies have obviously been told to concentrate (for now) on human manipulation of existing genes inside the plant, moving them around in ways that cross-breeding doesn't move them. They are then able to say that it "isn't GMO" because they are not taking fish genes and putting them into cats or tomatoes.

But it is still genetic engineering, they still don't know ultimately what physically moving one gene from a strand and slapping it on by human manipulation to another part of the code is going to do that plant 20 years down the line. And some of the few, really independent experiments, on what can happen to GMO foods are really terrifying.

That, and the fact that they often are not nearly as full of various good nutrients as eating old-fashioned, heritage varieties - which these Big Seed Companies have also mostly bought and try to control.

The guy giving the lecture at the grain mill and baking class I took talked about that too, how the big seed companies bought up the smaller companies and simply took many of the old seed varieties off the market. They "own" them now, so you can't have them - unless you trade with other people in seed exchanges and get some of the few that are still independently owned.

There were hints that one reason some really big money was behind BREXIT was so the UK could bring in GMO foods and American/other meats full of antibiotics that are also illegal in the EU (you can treat a sick animal, but you can't just feed them food laced with antibiotics or use chlorine to wash dead chickens.

I think that those reports are true, not that there might not be other good reasons for BREXIT but this was one of the bad ones.
 

Melodi

Disaster Cat
And they will not be labeled, the peasants will eat what they are given!
Government green-lights the development of 'gene edited' crops and livestock in the UK - and says they will be sold UNLABELLED in supermarkets
New legislation to speed up development of 'gene edited' crops to be introduced
It could pave way for bird flu-resistant chickens and climate change-proof wheat
Under previous European rules, gene editing of livestock and plants was banned
Will cut pesticide need and make farming more environmentally friendly — Defra
By SAM TONKIN FOR MAILONLINE

PUBLISHED: 00:01, 25 May 2022 | UPDATED: 09:38, 25 May 2022

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Shoppers will be unable to tell if they are eating 'gene-edited' foods as part of new government plans to speed up the development of crops and livestock with altered DNA.

The new Genetic Technology Bill, due to be introduced to Parliament today, could pave the way for bird flu-resistant chickens, wheat which can withstand climate change, and crops that are more nutritious.

But it will also allow these gene-edited products to be sold without being labelled.

Under previous European rules, gene editing of livestock and plants was banned along with genetically modified (GM) produce — dubbed 'Frankenfood'.

But post-Brexit, the Government is keen to embrace gene editing in an attempt to reduce the need for pesticides in farming, which would make it cheaper and more environmentally friendly.

Gene editing differs from GM foods because it alters the existing DNA of a plant or animal, rather than adding DNA from different species.

It could lead to the rolling out of tomato plants that are mildew-resistant to cut fungicide use or are fortified with vitamin D, as well as livestock that is resistant to disease or needs fewer antibiotics.


WHAT ARE GENE-EDITED CROPS AND HOW ARE THEY DIFFERENT TO GM PLANTS?
Gene editing promises to produce 'super-crops' by altering or cutting out genes that naturally occur in plants.

Unlike genetically modified (GM) plants, gene-edited (GE) crops contain no 'foreign' DNA from other species.

GE crops are produced using CRISPR, a new tool for making precise edits in DNA.

Scientists use a specialised protein to make tiny changes to the plant's DNA that could occur naturally or through selective breeding.

GM crops have had foreign genes added to their DNA - a process that often cannot happen naturally.

The US, Brazil, Canada and Argentina have indicated they will exempt GE crops that do not contain foreign DNA from GM regulations.

'Outside the EU we are free to follow the science,' said Environment Secretary George Eustice.

'These precision technologies allow us to speed up the breeding of plants that have natural resistance to diseases and better use of soil nutrients so we can have higher yields with fewer pesticides and fertilisers.'

Pesticides and herbicides used to treat crops often include controversial chemicals that can threaten insects and other wildlife — such as bee-killing neonicotinoids.

The new legislation will allow gene-edited crops to be approved in one year instead of up to ten.

However, critics have called for greater transparency for shoppers, who won't be able to identify which foods are gene-edited as products will be sold without being labelled.

Bright Blue, a Conservative think tank, said consumers should not be 'tricked', while Liz O'Neill of the anti-GM campaign group GM Freeze added that there should be clear labels so people know what they are buying and eating.

Gideon Henderson, Defra's chief scientific adviser, said there were currently no plans to introduce a labelling system for gene-edited products.

'The intention at present is not to introduce a labelling system for gene-edited products which are in many cases identical to those which could be produced in other ways through traditional breeding and cannot actually be identified,' he added.

'So it will be scientifically not sensible to label them as such. But the labelling issue does remain an active question.'

'Super tomato' is genetically engineered to produce as much vitamin D as two EGGS
'Super tomatoes' that have been genetically engineered to produce more vitamin D could help reduce deficiency of the vitamin around the world.

British researchers used a gene editing technique known as CRISPR to edit the gene involved in converting provitamin D3 into cholesterol.

They say editing this gene allows the tomato to keep more of the provitamin, which can be converted to vitamin D through UV exposure or sunlight.

The researchers from the John Innes Centre in Norwich claim the vitamin D you can get from eating one of these genetically modified tomatoes is equivalent to two eggs or 28 grams of tuna.

They could therefore help satisfy child and adult daily requirements for vitamin D3, reducing the risk of developing diseases such as cancer, Parkinson’s disease and dementia.

Earlier this week, Mr Eustice revealed that gene-edited crop production was to be sped up in the UK to help tackle the global food crisis brought on by Russia's invasion of Ukraine.

Russian blockades are preventing the export of key goods such as oils, wheat and corn from the 'breadbasket of Europe', leading to rising food prices and shortages globally including a major threat of famine in Africa.

Legislation to cut red tape and support the development of technology to grow more resistant, more nutritious, and more productive crops will be introduced in Parliament today.

The Genetic Technology (Precision Breeding) Bill will create a new category for gene-edited organisms to regulate them separately from GM organisms.

It will introduce new notification systems for research and marketing, and ensure information collected on precision-bred organisms is published on a public register.

The new legislation aims to speed up the development and commercialisation of crops and livestock bred with genetic editing, although the Government says it is taking a step-by-step approach by creating rules for plants first.

No changes will be made to the regulation of animals under the GM regime until measures are developed to safeguard animal welfare, the Environment Department (Defra) said.

It will also allow the importation of gene-edited foods from other countries, if they meet the same regulations.

'Substantial environmental, health and food security benefits can come from use of genetic technologies to precisely mimic breeding and improve our crops,' said Defra’s Chief Scientific Adviser, Gideon Henderson.

'The UK is home to some of the world’s leading research institutions in this area and these reforms will enable their scientists to use their expertise to make farming more resilient and our food healthier and more sustainable.'

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The rule changes apply to England, so gene-edited foods can be developed and produced by English scientists and farmers, but could also be sold in Scotland and Wales.

The Government has already allowed field trials in England of gene edited crops without having to go through a licensing process costing researchers £5,000 to £10,000, although scientists have to inform Defra of their tests.

Globally, between 20 and 40 per cent of all crops grown are lost to pests and diseases.

Precision breeding has the potential to create plant varieties and animals that have improved resistance to diseases.

Crispr-Cas9 is the primary gene-editing technique and is used to edit animal and plant DNA with great precision.

The hope is that as well as helping with foods, it could also be used to treat diseases caused by genetic mutations, from muscular dystrophy to congenital blindness, and even some cancers.

The first human trials of Crispr therapies are happening already, and researchers hope that they are on the brink of reaching the clinic.

However, some scientists claim to have uncovered evidence the gene-editing tool causes unwanted mutations that may prove dangerous — and is 'much less safe' than once thought.

The Government hopes the new legislation will lead to the production of wheat which can withstand climate change and crops that are more nutritious (stock image)
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The Government hopes the new legislation will lead to the production of wheat which can withstand climate change and crops that are more nutritious (stock image)

Others remain concerned it could create 'designer babies' by allowing parents to choose their hair colour, height or even traits such as intelligence.

The move was widely welcomed by scientists.

Dr Penny Hundleby, senior scientist at the John Innes Centre, said: 'If we are to meet the ambitious targets of addressing the demands of a growing population without further adding to the cost of living, and while also reducing the environmental impact of agriculture, we need to embrace all safe technologies that help us reach these goals.

'Gene editing and genome sequencing are great UK strengths and through the new Genetic Technology Bill they will move us into an exciting era of affordable, intelligent and precision-based plant breeding.'

Prof Martin Warren, Chief Scientific Officer at the Quadram Institute, added: 'The Genetic Technology Bill provides a wonderful opportunity to explore ways to address the nutritional-deficiency that is found in many crop-based foods.

'Gene editing allows for the development of plants with improved qualities that normally take many years to produce using traditional breeding programs.

'The ability to increase levels of key minerals such as iron and zinc and vitamins A, B and D in plants holds significant potential as a way to improve lifelong health through biofortification.'
 
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