Flu Antiviral shilajit

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Ten benefits of shilajit
Shilajit, also called mineral pitch, is the result of a long process of breaking down plant matter and minerals. It is a sticky, black, tar-like substance that comes from rocks in high mountain ranges.
Shilajit was traditionally sourced in India and Tibet, though it is now found in many other countries.
Shilajit has been used in traditional Indian Ayurvedic medicine for centuries, and the compounds in it appear to be beneficial for many conditions. In this article, learn about the benefits and possible side effects of this naturally-occurring substance.

Ten potential benefits of shilajit

When it is used correctly, shilajit may have several benefits for the body. This may be due in part to the high concentration of fulvic and humic acids, as well as many minerals.
1. Brain function
man holding a red pill and a glass of water
Share on PinterestShilajit is formed from slow decomposition of plant matter and is available as a supplement or powder.
The numerous compounds found in shilajit may be helpful for brain function, and may even aid Alzheimer’s therapy.
A study in the International Journal of Alzheimer’s Disease noted that shilajit is traditionally used for longevity and to slow aging. The compounds in it may help control cognitive disorders, such as Alzheimer’s.
Researchers expect shilajit to have an impact in preventing cognitive disorders, but more research is needed to explore these possibilities.
2. Aging
One study noted that fulvic acid, one of the key compounds in shilajit, acts as an antioxidant and anti-inflammatory compound. As such, it may help reduce free radicals and cellular damage in the body, which are two key factors in aging.
Daily supplementation of shilajit may contribute to overall vitality and a slower aging process in some people.
3. Anemia
Anemia develops when the blood does not have enough healthy cells or hemoglobin. There are many causes of anemia, including iron deficiency.
Iron deficiency anemia can cause numerous symptoms in the body, including:
Shilajit contains high levels of humic acid and iron, which may be helpful in treating iron deficiency anemia. It is important to explore this option with a doctor before taking supplements, however.
4. Antiviral
The wide range of minerals and compounds found in shilajit may also help fight off viruses. A research study noted that shilajit could fight off and kill many different viruses in isolated environments, including some herpes viruses.
Researchers commented that while it does appear to be effective, more studies carried out with live subjects are needed to back up these claims.
5. Chronic fatigue
A 2012 study published in the Journal of Ethnopharmacology found that shilajit helped reduce symptoms of chronic fatigue syndrome in test subjects.
Researchers noted that shilajit might help improve cell functions in the body, which means it may reduce fatigue at the source of the problem and increase energy levels naturally.
6. Altitude sickness
One of the claims made by traditional practitioners is that shilajit can help alleviate altitude sickness. The changes in pressure at high altitudes can greatly affect some people. Symptoms of altitude sickness range from body pain and fatigue to lung congestion and low oxygen in the brain.
Shilajit is a complex substance that contains more than 80 different minerals, as well as fulvic acid and humic acid. Because of this broad spectrum of beneficial components, shilajit is thought to help reduce many symptoms of altitude sickness.
It may help improve the brain’s cognitive processes, boost the immune system, and reduce inflammation, all of which could lessen altitude sickness.
7. Liver cancer
Shilajit also shows promise in fighting against certain types of cancer cells. One study found that shilajit helped force the destruction of cancerous cells in the liver.
It also stopped these cancer cells from multiplying. Researchers noted that their results show that shilajit has an anti-cancer effect, but more studies are needed.
8. Heart health
man having his blood pressure taken
Share on PinterestAs it may lower blood pressure, those with heart disease or hypotension should not take shilajit.
Shilajit may also protect the heart and improve heart health. A recent study using rats noted the protective effects shilajit has on the heart.
Animals who were treated with shilajit prior to cardiac injury had less damage to the heart than those who were not given shilajit.
It is important to note that shilajit may reduce blood pressure in some cases and should not be taken by anyone who has an active heart condition.
9. Obesity
Carrying extra weight can tire the muscles and put stress on the bones. A study in the Journal of Medicinal Food noted that people who were obese who took an oral supplement of purified shilajit responded better to exercise than those who did not.
Researchers noted that the shilajit seemed to activate genes in the body that helped the skeletal muscles quickly adapt to the new workout. This could mean less fatigue and more strength over time.
10. Male fertility and testosterone
Shilajit has also been studied to increase male fertility. One study gave 60 infertile men shilajit twice a day for 90 days.
After the test period, almost half of the men who completed the treatment showed an increase in total sperm count and sperm motility, or how many and how well the sperm move towards the egg, both of which are factors in male fertility,
Another study looked at the ability of shilajit to increase testosterone levels in healthy volunteers. Men between 45 and 55 years old were given shilajit for 90 days. At the end of this period, researchers noted significant increases in the levels of total testosterone.





Use

young woman holding a glass of milk in one hand and a glass of water in the other
Share on PinterestShilajit powder can be taken dissolved in water or milk.
Shilajit is available as a powder or as a supplement that can be dissolved in milk or water.
A person can dissolve a pea-sized portion of shilajit in liquid and drink it up to three times a day, depending on the instructions on the package.
The recommended dose of shilajit is 300 to 500 milligrams per day. However, it is important that a person speaks with a doctor before taking any natural supplements.


Potential side effects

Research suggests that shilajit is safe for long-term use as a dietary supplement. However, there are some potential side effects of using shilajit.
Shilajit may lower blood pressure, which can be dangerous for people on high blood pressure medications. People with an active heart disease or with a history of hypotension should avoid taking shilajit to prevent a drop in blood pressure.
The United States Food and Drug Administration (FDA) does not monitor natural supplements, so it is important to get the supplement from a reputable source. Low-quality shilajit may be tainted with heavy metals, free radicals, and even arsenic in some cases.


Takeaway

Shilajit has several health benefits and is a safe and effective supplement when used correctly. It is always best to speak to a doctor about the correct dosage in each case.
Working directly with a doctor can also help a person monitor any potential side effects.

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Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
Carlos Carrasco-Gallardo, Leonardo Guzmán, and Ricardo B. Maccioni *
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This article has been cited by other articles in PMC.

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Abstract
Shilajit is a natural substance found mainly in the Himalayas, formed for centuries by the gradual decomposition of certain plants by the action of microorganisms. It is a potent and very safe dietary supplement, restoring the energetic balance and potentially able to prevent several diseases. Recent investigations point to an interesting medical application toward the control of cognitive disorders associated with aging, and cognitive stimulation. Thus, fulvic acid, the main active principle, blocks tau self-aggregation, opening an avenue toward the study of Alzheimer's therapy. In essence, this is a nutraceutical product of demonstrated benefits for human health. Considering the expected impact of shilajit usage in the medical field, especially in the neurological sciences, more investigations at the basic biological level as well as clinical trials are necessary, in order to understand how organic molecules of shilajit and particularly fulvic acid, one of the active principles, and oligoelements act at both the molecular and cellular levels and in the whole organism.
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1. Introduction
Shilajit also known in the north of India as salajit, shilajatu, mimie, or mummiyo is a blackish-brown powder or an exudate from high mountain rocks, especially in the Himalayans mountains between India and Nepal, although it has been also found in Russia, Tibet, Afghanistan, and now in the north of Chile, named as Andean Shilajit [1]. Shilajit has been known and used for centuries by the Ayurvedic medicine, as a rejuvenator and as antiaging compound. There are two important characteristics of a rasayana compound in the ancient Indian Ayurvedic medicine: that is, to increase physical strength and to promote human health [2]. The health benefits of shilajit have been shown to differ from region to region, depending on the place from which it was extracted [3, 4].
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2. Origins of Shilajit
Considering its unique composition as a phytocomplex, very rich in fulvic acid, researchers hypothesize that Shilajit is produced by the decomposition of plant material from species such as Euphorbia royleana and Trifolium repens [4, 5]. This decomposition seems to occur through centuries, and on this basis, shilajit is considered a millenary product of nature. However, further studies have identified that several other plant organisms may generate shilajit, such as molds as Barbula, Fissidens, Minium, and Thuidium and other species like Asterella, Dumortiera, Marchantia, Pellia, Plagiochasma, and Stephenrencella-Anthoceros [4].
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3. Molecular Composition of Shilajit
Shilajit is composed mainly of humic substances, including fulvic acid, that account for around 60% to 80% of the total nutraceutical compound plus some oligoelements including selenium of antiaging properties [6, 7] (Figure 1). The humic substances are the results of degradation of organic matter, mainly vegetal substances, which is the result of the action of many microorganisms. Components are divided operationally in humins, humic acid, and fulvic acids according to their solubility in water at different pH levels. Humins are not soluble in water under any pH condition. Humic acid is soluble in water under alkaline conditions and has a molecular weight of 5–10 kDa. Fulvic acid is soluble in water under different pH conditions, and because of its low molecular weight (around 2 kDa), it is well absorbed in the intestinal tract and eliminated within hours from the body [8, 9]. It is likely that the curative properties attributable to shilajit are provided by the significant levels of fulvic acids that shilajit contains, considering that fulvic acid is known by its strong antioxidant actions [9] and likely has systemic effects as complement activator [10]. Recent studies on the composition of Andean Shilajit in Chile have evidenced an ORAC index between 50 and 500 Trolox units/g of material, which is substantially higher than Noni and blueberries (Quinteros et al., unpublished data). In this context, shilajit seems to be a powerful antioxidant phytocomplex.
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Figure 1

Shilajit, its main components, and potential uses based on properties of fulvic acid. This phytocomplex known as shilajit is mainly composed of humic substances. One of them, fulvic acid, is known by its properties such as antioxidant, anti-inflammatory, and memory enhancer. Novel investigations indicate that fulvic acid is an antiaggregation factor of tau protein in vitro [1], which projects fulvic acid as a potential anti-Alzheimer's disease molecule.
Other molecules present in shilajit preparations are eldagic acid, some fatty acids, resins, latex, gums, albumins, triterpenes, sterols, aromatic carboxylic acids, 3,4-benzocoumarins, amino acids, polyphenols, and phenolic lipids [3, 6, 11]. Certainly its molecular composition varies from region to region. Newer investigations based on high-performance size exclusion chromatography (HP-SEC) show that shilajit contains specific molecular species of polysaccharides and lignins [10]. As humic components, humins, humic acids, and fulvic acids are found in all shilajit preparations, being the last one, fulvic acids, the biologically active compound, along with dibenzo-α-pyrones, which acts as carrier of other substances [3].
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4. Traditional Uses of Shilajit
Shilajit is an important, known component of the ayurvedic medicine given its characteristics as a rasayana. In this context, health benefits such as an increase in longevity, rejuvenating, and arresting aging roles have been attributed to it [3]. Traditionally, shilajit is consumed by people from Nepal and the North of India, and children usually take it with milk in their breakfast. The Sherpas claim to have shilajit as part of their diet; they constitute a population of strong men with very high levels of a healthy longevity. Our laboratory has found evidence on the high activity of the Andean form of shilajit in improving cognitive disorders and as a stimulant of cognitive activity in humans [1] (Table 1).
Table 1
Morphometric study of primary cultured rat hippocampal cells exposed to Shilajit and the Brain Up-10 formulae that contain Shilajit plus complex B vitamins (Vit B6, B9, and B12).
Control​
Shilajit**​
Brain Up-10*​
Neuronal cells per field​
367 ± 23​
345 ± 42​
396 ± 16.0​
Percentage of cells with neuronal processes​
18.0 ± 2.1​
26.0 ± 3.2**​
43.0 ± 3.1**​
Fraction of axon-like processes​
0.22​
0.29​
0.41​
Processes length (μm)​
17.4 ± 7.2​
26.0 ± 4.5**​
39.6 ± 8.0**​
Hippocampal cells were grown in Petri dishes in the presence of either 10 mg/mL Shilajit or the formulation of Brain Up-10 [30] plus vitamins of the B complex. In the control, cells were grown in culture medium without Shilajit or the formulation. Mean of 5 determinations (n = 5) (significance of differences with respect to control, **P < 0.001).

Considering the actions of fulvic acid in preventing tau self-aggregation into pathological filaments, this compound appears to be of interest for prevention of Alzheimer's disease [1]. Other common traditional uses include its action in genitourinary disorders, jaundice, digestive disorders, enlarged spleen, epilepsy, nervous disorders, chronic bronchitis, and anemia [2]. Shilajit has been also useful for the treatment of kidney stones, edema, and hemorrhoids, as an internal antiseptic, and to reduce anorexia. Also, it has been claimed in India to be used as yogavaha [12, 13], that is, as synergistic enhancer of other drugs. Organic components of shilajit play also a role in transporting different mineral substances to their cellular targets.
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5. Novel Investigations
Preclinical investigations about shilajit indicate its great potential uses in certain diseases, and various properties have been ascribed, including (1) antiulcerogenic properties [14]; (2) antioxidant properties [15, 16]; (3) cognitive and memory enhancer [1, 10, 17]; (4) antidiabetic properties [18]; (5) anxiolytic [12]; (6) antiallergic properties and immunomodulator [2, 19, 20]; (7) anti-inflammatory [21]; (8) analgesic [16]; antifungal properties [22]; (9) ability to interact positively with other drugs [23]; (10) protective properties in high altitudes [24]; (11) neuroprotective agent against cognitive disorders [1, and Farias et al. unpublished clinical trials]. Unfortunately shilajit lacks systematic documentation and well-established clinical trials on its antioxidative and immunomodulatory actions in humans, and it is expected that considering the reported benefits evidenced from trials will be obtained in the near future [25].
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6. Patenting
A few patents already exist that protect the use of shilajit in India and Nepal, such as US Patent 5,405,613—vitamin/mineral composition [26]; US Patent application number 20030198695—Herbo-mineral composition [27]; US Patent number 6,440,436—Process for preparing purified shilajit composition from native shilajit [28]; US Patent number 6,558,712—Delivery system for pharmaceutical, nutritional and cosmetic ingredients [29]. Other recent patent about a phytocomplex with vitamins added is WO 2011/041920 [30].
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7. Potential Risks
Studies indicate the shilajit consumption without preliminary purification may lead to risks of intoxication given the presence of mycotoxin, heavy metal ions, polymeric quinones (oxidant agents), and free radicals, among others [3]. Therefore, a purified, ready-for-use preparation for human consumption must be used. However, recent studies indicate that several ayurvedic products including shilajit and other Indian manufactured products commercialized by the Internet may contain detectable heavy metals levels as lead, mercury, and arsenic [31]. This study showed the presence of heavy metals and other minerals, including gems, is associated with the belief that when mixed with shilajit or other herbal preparations they generate a better response from the body in a synergic manner. This is what is known as rasa-shastra in ayurvedic medicine. Rasashastra experts claim that if this is prepared, administered, and consumed properly, it is safe and has therapeutic advantages [31]. It is worth considering that recent clinical reports indicate cases of lead poisoning in patients who have used ayurvedic products against weakening [32, 33].
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8. Commentary and Discussion
Shilajit has a comfortable position as the rasayana because of its excellence, well known in the Eastern culture, and now being introduced with great interest in the occidental world. The vast majority of published papers on this theme are from India, leaving this sector of the planet as an expert in their field, since this is a product that is extracted, marketed, and investigated in these latitudes. However, this generates a segmentation of shilajit, relegating it only to what has always been assumed: a natural product that is part of natural alternative medicine and not as a result of medical and biotechnology innovation worldwide. This is evidenced quite clearly by reviewing the literature today, and note that the journals where studies on shilajit are published (jobs are plentiful) are mainly reviewed in the Eastern. Given this, it is necessary that shilajit break the cultural paradigm and enter into the rest of the world by the hand of rigorous research at the molecular and cellular levels, which could elucidate the interactions of the active ingredients of the different shilajit preparations with biomolecules. This will facilitate our understanding of their mechanisms of action.
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9. Conclusion
Shilajit is a potent and very safe dietary supplement, potentially able to prevent several diseases, but its main medical application now appears to come from its actions in benefit of cognition and potentially as a dietary supplement to prevent Alzheimer's disease. In essence, this is a nutraceutical product. Considering the expected impact of shilajit applications in the medical field, especially in neurological sciences, more investigations at the basic biological level are necessary, and certainly well-developed clinical trials, in order to understand how its active principles act at molecular and cellular levels.
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Acknowledgments
These investigations have been supported by a CORFO Project 10ANT 8051, VRI FONDEF project, and FONDECYT 1110373 from CONICYT and a grant from the Alzheimer's Association, USA. Authors acknowledge important collaboration of Constanza Maccioni.
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References
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Humic Acid Substances in Animal Agriculture


Conclusion: There is no doubt that HA has many beneficial effect like antibacterial, antiviral and anti inflammatory in animals, improves immune system, stress management and reduce odour in faeces. It also has positive effect on liver functioning. Ultimately reduces mortality and increases growth in poultry. But the level of benefits is now questionable for ruminants because due to its antimicrobial affect may cause depression of protein synthesis by reducing rumen microorganism. Supported literature those indicates the HA as growth promoter in ruminants seems weak in this aspects and facing question. It’s affect as goitrogenic substance in rat is rejected in case of poultry by recent findings. So, in relation to growth promoter, using routinely is not so positive but where health risk is higher might be reflect beneficial due to protection of diseases. It is also difficult to compare the actual effects of HA preparations due to different sources and preparations as well as because rearing of animal in various region of the world differing the climate


 

TammyinWI

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Valuable info. Thank you. Never heard of it before, but I am convinced it helps. Always something to learn here.

I put some in my virtual cart and will order very soon!
 

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I have had it before. A tip, get it in dry powder form not liquid.

I am putting in an order also tomorrow.
 
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