9/22/07-9/28/07|Weekly Bird Flu Thread:Influenza A virus movement is tracked

JPD

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Influenza A virus movement is tracked

http://www.sciencedaily.com/upi/ind...e=UPI-1-20070920-13061400-bc-us-influenza.xml

STATE COLLEGE, Pa., Sept. 20 (UPI) -- A U.S. study has found the influenza A virus isn't dormant during summer but migrates globally and mixes with other viral strains.

Pennsylvania State University researchers said their finding resolves a key debate on what the virus does during summer when it isn't infecting people.

"Nobody really knows why flu is a winter disease in the temperate regions and more continuous in the tropics," said Penn State biology Professor Edward Holmes.

Holmes said the key question is whether the virus settles into a dormant state or whether it migrates to viral reservoirs in the tropics, from where it is later reintroduced.

To test the migration theory, Holmes, graduate student Martha Nelson and National Institutes of Health colleagues Lone Simonsen, Cecile Viboud and Mark Miller analyzed the influenza A virus genomes of 900 virus samples from New Zealand, Australia and New York state

They discovered the genomes of 52 viruses from New York are closely related to viruses that circulate during the winter (April to October) in New Zealand and Australia. That, they said, suggests seasonal viral traffic across the equator contributes to new epidemics in both hemispheres.

The findings appear in the current issue of PLoS Pathogens.
 

JPD

Inactive
Africa needs funds to combat bird flu

http://www.dawn.com/2007/09/23/ebr18.htm

ADDIS ABABA, Sept 22: African nations are concerned that a slump in funding from the international community could hamper their efforts to combat bird flu on the continent, officials said.

“The main challenge today in our efforts to combat bird flu in Africa is the level of funding,” Modibo Traore, head of the African Union’s Inter-African Bureau of Animal Resources, told AFP.

He was speaking after a meeting of experts designed to unify African efforts against the epidemic that wrapped up Friday in Addis Ababa.

“The trend is negative in the international community and among donors, who may be expected the disease to have more dramatic effects,” he explained.

Asia has been the worst-hit continent since the virus’ deadly H5N1 strain first appeared in 2003 but human infections have also been reported in Egypt, Nigeria and Djibouti.

With a total of 38 human cases confirmed by the World Health Organisation and 15 deaths since the start of the year, Egypt has been one of the world’s most affected countries in 2007.

The Addis Ababa meeting sponsored by the African Union was aimed at reassuring donors and coordinating strategies among the pan-African body’s 53 member states.

The chairman of the World Organisation for Animal Health, Bernard Vallat, said the crisis was being contained but stressed that sustained efforts were needed to prevent further outbreaks.

“At an international level, the epidemic is receding among wild birds and poultry farms. But there are occasional outbreaks in Ghana and Togo,” he said.

No human cases have been detected in the two countries, which border Nigeria.

“It’s reassuring that after three years, the virus still isn’t being transmitted from human to human, but we have to remain vigilant because the risk of a pandemic is still serious,” Vallat added.—AFP
 

JPD

Inactive
Suspected bird flu death in Indonesia

http://www.channelnewsasia.com/stories/afp_asiapacific/view/301497/1/.html

JAKARTA: An Indonesian woman suspected of being infected with bird flu has died in the West Java city of Bandung, hospital sources there said Sunday.

Samples from the 30-year-old woman have been sent for testing in Jakarta, said a staff member at Bandung's Hasan Sadikin general hospital who only identified himself as Herdi.

Two tests must come back positive for the H5N1 virus before a victim is confirmed as part of the official bird flu death toll in Indonesia, which is the highest in the world at 85.

The woman, who died on Saturday, was showing symptoms of bird flu infection, such fever, coughing, breathing difficulties and low red blood count.

Herdi declined to give further details, but the Koran Tempo said that the victim fell sick a few days after one of her pet birds died. Transmission usually occurs directly from birds to humans.

The kind of bird involved has not been identified.

If confirmed to be infected with the H5N1 strain of the virus, the woman would be the 86th human fatality in the country. Twenty-one other people have been infected by the deadly H5N1 virus strain that causes bird flu, but have so far survived.

H5N1 is endemic in birds across nearly all of Indonesia.

Scientists worry that the virus will eventually mutate into a form that is much more easily transmissible between humans, triggering a disastrous global pandemic. - AFP/ac
 

JPD

Inactive
Singapore scientists say they have developed
quick bird flu detection device

http://hosted.ap.org/dynamic/storie...ME&TEMPLATE=DEFAULT&CTIME=2007-09-24-06-23-14

By GILLIAN WONG
Associated Press Writer

SINGAPORE (AP) -- Scientists in Singapore said Monday they have developed a portable device that can detect the H5N1 bird flu virus in less than half an hour.

The palm-sized "lab-on-a-chip" device is able to quickly detect the presence of the H5N1 virus from a throat swab or stool samples from humans and poultry, Dr. Masafumi Inoue, one of the researchers from the Singapore-based Institute of Molecular and Cell Biology, told The Associated Press.

The instrument uses a magnetic force to manipulate reagents to rapidly determine whether samples are positive for the deadly H5N1 strain, Inoue said.

The device could help fight an outbreak by providing early warnings, researchers said. Current bird flu tests take about three to four hours to complete and must be conducted in a lab, Inoue noted.

"Complex biochemical tasks can thus be processed in a fashion similar to that of a traditional biological laboratory on a miniature scale," said project leader Dr. Juergen Pipper of the Institute of Bioengineering and Nanotechnology, also in Singapore.

The device could potentially be 40 to 100 times cheaper than current bird flu detection tests, said Inoue. It can also be adapted to test for severe acute respiratory syndrome, HIV and hepatitis B.

Research on the testing tool was published in an advance online edition of the journal Nature Medicine.

"It may well be the answer to all our prayers, but we don't know anything about it yet," said Peter Cordingley, spokesman for the World Health Organization's Western Pacific region.

Avian influenza has killed at least 200 people worldwide, but remains hard for people to catch. Experts fear it could mutate into a form that spreads easily among humans, potentially sparking a pandemic.
 

JPD

Inactive
2 Indonesian children hospitalized with bird flu symptoms

http://news.xinhuanet.com/english/2007-09/24/content_6784596.htm

JAKARTA, Sept. 24 (Xinhua) -- Two Indonesian children were in critical condition at a hospital in Riau Province with doctors strongly suspecting them of having developed bird flu symptoms in the country where 84 people already died of the virus, according to local media on Monday.

The two boys age one and three are being treated in isolated rooms at the Arifin Ahmad Hospital in the provincial capital of Pekanbaru, leading news website Detikcom said.

"They are suffering high fever and respiratory problems," Dr. Azizman Saad with the hospital was quoted by Detikcom as saying, adding "the condition of their lungs is deteriorating, with excessive activities of liquid production."

Laboratory tests by the hospital indicated that the two patients had bird flu but further tests in Jakarta are needed for confirmation.

Over the last two years, bird flu killed three people in Riau alone.
 

JPD

Inactive
U.S. financial institutions undergoing three-week test of fake flu pandemic

http://www.mytelus.com/money/news/article.do?pageID=ex_business/home&articleID=2759976

Martin Crutsinger, THE ASSOCIATED PRESS

WASHINGTON - Don't be alarmed if your local bank teller is looking a bit sickly over the next three weeks. It is only a cyber-illness.

Hundreds of U.S. banks and other financial institutions are participating in the largest test of its kind ever conducted to ensure America's financial system can keep functioning in case of an outbreak of pandemic flu.

The test began Monday and is scheduled to run for three weeks. More than 2,700 financial institutions have signed up to participate, about five times the number the Treasury Department expected.

"This shows how much the business sector is focused on pandemic flu planning," Valerie Abend, Treasury's deputy assistant secretary for critical infrastructure protection, said in an interview.

Treasury, aided by other federal agencies and the private sector, has devised a three-week script for how a serious outbreak of bird flu might affect operations at banks, from the very biggest to the smallest, as well as at credit unions, securities firms and insurance companies.

The exercise also covers companies that provide critical behind-the-scenes processing to keep the flow of cheques and money circulating around the country.

According to the doomsday scenario devised by Treasury, a number of cases of bird flu in humans are reported overseas and the illness spreads quickly to the United States by people travelling on international flights.

From that beginning, the Treasury scenario presents financial institutions with a number of challenges over the course of the three-week exercise. The financial institutions got the first week's scenario over the weekend from an Internet site where the test is being conducted.

The whole exercise is part of a plan unveiled by U.S. President George W. Bush in May 2006 directing various government agencies to upgrade their planning for pandemic outbreaks. The Government Accountability Office earlier this month criticized the administration for failing to conduct sufficient tests to make sure that the agencies understand their responsibilities.

One of the biggest challenges financial institutions will face is how to cope with absenteeism. In week one, the Treasury exercise directs the financial organizations to assume that 25 per cent of their work force is not coming to work, either because of illness or because of fear of being infected or because they are staying home to take care of children who can't go to school because the schools have closed.

To decide who is absent, the Treasury directs the institutions to assume that everyone whose last name begins with certain letters, which could cover the bank president down to the local teller, cannot come to work. The 25 per cent absentee rate will jump to 49 per cent in week two.

Abend said the various projections were compiled with the help of government scientists. Government financial regulators also helped put together scenarios on how the stock market will behave as well as what the value of the dollar and various commodities such as oil will be doing.

The dollar is projected to rise as investors seek a safe haven with the spreading global illness while stock prices are projected to fall because of worries about what the pandemic will do to economic activity.

Absent employees won't be the only troubles facing the financial institutions. Under Treasury's scenario, they also will have to cope with shrinking Internet bandwidths as more and more people try to work from home. Cash withdrawals from ATM machines are expected to rise sharply and getting the machines refilled will present problems because of rising absentee rates at the armoured car companies and the difficulty of getting fuel for the armored trucks as gasoline refineries curtail their production.

By the end of the three weeks, Abend said the government and the institutions participating will have a much better idea of just what a flu pandemic will mean in the United States. She said the test should get the institutions thinking about where they need to improve their contingency plans.

"What would you do if you don't have access to key people? Have you cross-trained enough employees to sufficiently cover that?" she asked. "We want to do a really robust test."

Of the more than 2,700 organizations participating, two-thirds are banks, 20 per cent are securities firms and 10 per cent are insurance companies. The size of the firms ranges from the very largest with more than 100,000 employees to small institutions with fewer than 250 employees.

After the three-week exercise is completed, Treasury plans to write a report detailing how institutions performed and where planning needs to be upgraded. The organizations will also be given the opportunity to make suggestions on any areas where they believe government regulations need to be amended to allow for a better response to a pandemic.

"The after-action report will allow institutions to benchmark their capabilities against other institutions," Abend said.
 

JPD

Inactive
Bird flu stalking Tanzanian communities, govt...

http://www.ippmedia.com/ipp/guardian/2007/09/24/99036.html

2007-09-24 09:00:33
By Anaclet Rwegayura, PST, Addis Ababa

The government has warned that Tanzania was still at the risk of avian flu, and urged the general public to understand the disease and adopt basic hygiene practices for self-protection.

Livestock Development deputy minister Charles Mlingwa said in Addis Ababa last week that though Tanzania was prepared for any eventuality with regard to bird flu, an outbreak of the highly pathogenic disease could have serious socio-economic repercussions on domestic poultry production and public health.

Addressing the third general assembly and executive meeting of the African Livestock Development (ALive) platform, Mlingwa said a multisectoral emergency preparedness and response plan was already in place to deal with bird flu in the country.

The plan had seven main components that included capacity for early warning detection, capacity to contain avian flu at source, reduction of opportunity for human infection, improvement of awareness and information, research and coordination.

However, inadequate funding had curtailed implementation of the plan, Mlingwa said.

As a result it was currently focused on surveillance, detection and diagnosis of the disease, public education and awareness.

Underlining the safe handling of birds, the deputy minister said parents and teachers should tell children not to touch sick birds.

Wildlife, environment and forestry workers too had to be informed about the risks of highly pathogenic avian flu, how to protect themselves and how to report to proper authorities for action, he said.

`The biggest group of all people in contact with poultry livestock farmers and poultry keepers needs to change behaviour as they are the greatest risk group,` Mlingwa added.

Partnership programmes were under way in several African countries to prevent and control avian and human influenza epidemics.

For its laboratory strengthening, Tanzania had so far received USD700,000 from the US Agency for International Development (USAID) and USD100, 000 from UNICEF for public awareness creation.

In addition, the UN Food and Agriculture Organisation had provided the Tanzanian government with USD40,000 for surveillance, diagnosis and protective gear to strengthen the capacity to prevent and control highly pathogenic avian influenza.
 

JPD

Inactive
US Bank "Flu" Test now Underway

http://technocrat.net/d/2007/9/25/27589

# US banks and securities firms are running a bad case scenario bird flu epidemic test. Different banks, thousands of them, will have selected employees, based on last name first letter, stay out of work (apparently just "cyber"), from the bank president on down, along with other projected scenarios, a wargame in other words. This is a three week test, with 25% to 49% "absenteeism" rates planned.
# .."One of the biggest challenges financial institutions will face is how to cope with absenteeism. In week one, the Treasury exercise directs the financial organizations to assume that 25 percent of their work force is not coming to work, either because of illness or because of fear of being infected or because they are staying home to take care of children who can't go to school because the schools have closed."....more direct deposits there

This is the website for the Pandemic flu test, but not much there without being a connected one with a protected login. FWIW.
 

JPD

Inactive
Tests clear suspected bird flu death in Indonesia

http://www.khaleejtimes.com/Display...usiness_September643.xml&section=business&col

25 September 2007


JAKARTA - Two tests on samples from an Indonesian woman feared to have died of bird flu at the weekend have cleared her of carrying the virus, a health ministry official said Tuesday.

“Both test results were negative,” said Ningrum, a doctor on duty at the health ministry’s bird flu information centre.

She was referring to a 30-year-old woman who died in hospital in the West Java city of Bandung on Saturday displaying symptoms of infection with the H5N1 virus.

Two tests, usually of samples of blood and tissue, must come back positive for the virus before a victim is confirmed as infected in Indonesia, where the death toll of 85 from avian influenza is the highest in the world.

Scientists worry that the H5N1 virus will eventually mutate into a form easily transmissible between humans, triggering a disastrous and deadly global pandemic.
 

JPD

Inactive
CIDRAP: Promising Practices: Pandemic Preparedness Tools

http://www.pandemicpractices.org/pr...id=27569369CC97D56C8F1BC33637BFB4E4?page=home


This project aims to enhance public health preparedness for an influenza pandemic and conserve resources by sharing promising practices.

CIDRAP and the Pew Center on the States (PCS) launched this initiative to collect and peer-review practices that can be adapted or adopted by public health stakeholders. The project was conceived and funded by The Pew Charitable Trusts.

This collection of more than 130 practices represents a yearlong effort. Our Advisory Committee, composed of state and local public health and healthcare experts in pandemic influenza preparedness nationwide, selected the categories and topics at left.

Pandemic planners and others submitted materials, chiefly via surveys. The practices in this project come from 22 US states and 33 counties. If your agency isn’t included (click on the map to check) or if your state is already included but you have more practices to share, you can still submit practices.

Practices are chosen through a peer-review process. More than 25 US experts reviewed the materials here. Portions of reviewers' comments have been incorporated into a project description to provide greater context for each practice.

You can use these practices immediately. Please credit the authoring agencies and review the project descriptions for any other conditions of use.
 

JPD

Inactive
Bird flu forces Bangladesh to cull chickens

http://africa.reuters.com/commodities/news/usnDHA259917.html?rpc=401&

DHAKA, Sept 27 (Reuters) - Bangladesh culled some 5,000 chickens after bird flu infected a farm in the northern region of the country, officials said on Thursday.

"The chickens were buried on Wednesday after H5N1 virus was detected at a farm near Bogra district town 250 km (150 miles) (156 miles) north of the capital Dhaka," an official of the livestocks department said.

Bird flu was first detected near the capital in March and has since spread mostly to northern districts.

Eighteen out of Bangladesh's 64 districts have been affected by the virus since March, but there have been no cases of human infection. The virus has forced authorities to cull 262,000 chickens.
 

JPD

Inactive
H5N1 found in Thailand's Phichit province

http://news.xinhuanet.com/english/2007-09/27/content_6802737.htm

BANGKOK, Sept. 27 (Xinhua) -- Preecha Ruengchan, governor of northern Thailand's province of Phichit, called an urgent meeting with livestock officials on Thursday after birds there were found to have died without cause.

Preecha is considering whether to declare Phichit the bird flu zone, local newspaper Bangkok Post reported.

Thawatpong Paekwamdee, chief of Taphan Hin district of the province, said that test result of carcasses of chickens raised by a villager were found to have the H5N1 virus. The local authorities have killed 90 chickens within 1-km radius from the location.

Transportation of birds is prohibited in the area unless receiving authorization from authorities, who are keeping a close watch on the spread of the virus within 5-km radius.
 

JPD

Inactive
H7N3
Western Canada poultry farm quarantined

http://news.yahoo.com/s/afp/2007092...u2_070927191835;_ylt=A0WTUc_9EvxGHcoAAhCTvyIi

OTTAWA (AFP) - A poultry farm in Saskatchewan, in western Canada, was quarantined Thursday after avian flu was discovered on site, said the Canadian Food Inspection Agency.
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"It may be difficult to identify the source of the virus, but the possibility of exposure to wild waterfowl -- which are the natural hosts for the virus -- cannot be discounted," the government agency said in a statement.

Tests showed chickens were infected with the H7N3 pathogen, which is not lethal to humans, on the farm about 100 kilometers (62 miles) north of Regina, the provincial capital.

This virus is not the same as the strain circulating in Asia, Africa and Europe, which has been associated with human illness.

"In this case, the affected birds were not destined for immediate slaughter and were not producing eggs for human consumption," the CFIA said.

Even so, all of the birds will be euthanized, the agency said, and to limit potential spreading of the virus a three-kilometer (1.9-mile) restricted zone has been set up around the farm.

In 2005, more than 60,000 ducks and other fowl were slaughtered in westernmost British Columbia province after another strain of avian flu was discovered on two local farms.

Previously, 17 million birds were slaughtered in the province in 2004 after an outbreak.
 

JPD

Inactive
H7N3
Avian flu confirmed on Saskatchewan farm

http://www.canada.com/vancouversun/news/story.html?id=40109032-47c3-4943-81bb-602181c19d4f&rfp=dta

CanWest News Service

Friday, September 28, 2007

OTTAWA -- A large poultry farm in Saskatchewan is under quarantine following an outbreak of avian flu.

Officials with the Canadian Food Inspection Agency say the outbreak of virus H7N3 -- a strain of avian flu deadly to birds but not to humans -- was detected in one barn at the operation about an hour north of Regina on Sunday. A veterinarian reported the outbreak after hundreds of chickens began dying, and CFIA quarantined the entire operation Sunday.

"There are no effective barriers around that barn, so we're assuming all of the birds at this operation are now infected," said Dr. Jim Clark, CFIA national manager of the Avian Influenza Working Group.

He said that while this strain poses no real risk to the human population, it is "highly pathogenic" in birds.

"This came as a bit of a shock to all of us," he said.

All 45,000 chickens at the unnamed operation were to be killed with carbon dioxide gas Thursday night, and the facilities will be sterilized. All other poultry operations within a 10-kilometre radius will be tested for the virus.
 

JPD

Inactive
Bird flu 'can infect unborn child'

http://ukpress.google.com/article/ALeqM5h1Y9XCAT67ELfV_tgOiCmV9tNjGg

The deadly H5N1 strain of bird flu can pass from pregnant women to their unborn children, researchers have said.

Scientists in China discovered viral cells in an unborn baby and also proved the virus can move from the lungs to other parts of the body.

The results show the virus is even more potent than was at first feared. Common flu viruses are not thought to pass to unborn children.

Health experts warn the spread of H5N1, which can pass from birds to humans, could presage the rise of a global flu pandemic.

They fear that if the virus mutates so it can pass easily from humans to humans, millions could die.

Researchers at Peking University, Beijing, found the virus in lungs, windpipe and brain, during post-mortem examinations on a man and pregnant woman killed by the virus.

In the foetus they found parts of the virus in the lungs, immune system and the liver.

Professor Jiang Gu said: "This study has shown the capacity for human vertical transmission of the H5N1 virus... [this] warrants careful investigation, since maternal infections with common human influenza virus are generally thought not to infect the foetus."

"We have shown that H5N1 virus spreads beyond the lungs. These newly obtained data are important in the clinical, pathological and epidemiological investigation of human H5N1 infection, and have implications for public-health and health care providers."

More than 150 people worldwide have been killed by the virus. It was first found in Britain in a mute swan in Scotland in April last year. The virus was found in a Bernard Matthews farm in Holton, Suffolk, earlier this year.
 

Sully

Inactive
JPD, thanks for keeping us updated on this. During the summer months I tend to forget about the Avian flu but now that the flu season is getting near and bitds are migrating I'm getting a little nervous again.

Sully
 
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