Oct/10 H5N1 Continues It's Advance

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<B><font size=+1 color=red><center>Suspect H5N1 Wild Bird Flu Case Hospitalized in Turkey</font>

<A href="http://www.recombinomics.com/News/10100502/H5N1_Turkey_Case_Hospitalized.html">Recombinomics Commentary</A>
October 10, 2005

One person whose name has not been released has been taken to a local hospital on suspicion of having contracted the disease.</B></center>
The case listed above is the first reported suspect case in Turkey. H5 has been confirmed in Turkey and the large number of poultry deaths strongly implicate H5N1. However, there have been no confirmed human cases associated with the H5N1 wild bird flu in Russia, Kazakhstan, and Mongolia.

However, H5N1 evolves, and the wild bird strain is virulent in a wide range of bird species and the Qingahi Lake versions have the human PB2 polymorphisms, E627K.
 
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<B><font size=+1 color=purple><center>Continent on alert after bird flu hits three states </font>
By Stephen Castle, in Brussels
Published: 10 October 2005
<A href="http://news.independent.co.uk/europe/article318334.ece">The Independant Online</A>
Europe was put on a continental alert for avian flu yesterday as Turkey and Romania culled hundreds of birds and quarantined villages after reported outbreaks in both countries. </B></center>
Health officials across the continent increased surveillance for a strain of the disease that could mutate into one which spreads easily among humans. The so-called Spanish flu outbreakof 1918, which has been linked to the current strain, killed between 20 and 40 million people.

Romania has suffered suspicious bird deaths in seven locations and has slaughtered more than 1,000 animals. Turkey culled 2,000 chickens and turkeys after reporting its first outbreak of avian flu, which is commonly spread by migratory birds, on a farm near the Aegean Sea.

So far there have been no confirmed cases in Europe of the H5N1 strain of the virus, which has killed 65 people and millions of birds in Asia since 2003. Romania is still conducting tests, and the European Commission said that no cases of avian flu had yet been formally confirmed there.
Two years ago, an outbreak in the Netherlands led to the cull of 30 million birds. Health officials there have only recently lifted the most draconian restrictions designed to prevent contact with migrating birds.

In Europe there is growing concern at the lack of preparedness across the continent for a pandemic if the H5N1 strain arrives. Last week the Council of Europe Parliamentary Assembly said there was a "flagrant lack" of vaccines and anti-viral medicines to combat a pandemic. It said that the countries most at risk were facing the pandemic alone, "without the necessary financial resources to buy anti-viral vaccines and medicines to build up adequate stocks".

In Turkey the Hurriyet newspaper said that up to 16,000 animals would be slaughtered and that the affected district of Kiziksa will remain under quarantine for 21 days. Stray dogs in the area were being killed as a precaution.

Officials say the infected turkeys in Kiziksa probably contracted the disease from migratory birds from the Ural mountains heading for a nearby natural park called Bird Paradise.

Hurriyet reported that Mehmet Eksen, owner of the stricken Turkish farm, feared for his own health. The paper quoted him as saying: "I cried when I witnessed the death of my turkeys. I cannot forget those moments ... But now I think of myself and what will happen to my health. I cannot go near my wife and children."

In Brussels, Philip Tod, spokesman for the European Commission, said: " We are in a heightened state of vigilance. We have surveillance measures in place for poultry and wild birds. All member states are carrying out surveillance jointly financed with the EU.

"Member states have been asked to increase border inspections on live birds and poultry and we have instructed them to increase hygiene measures.

"These measures were taken as a response to the spread of avian flue to Siberia and Kazakhstan.

"We are working with the member states to prepare for the eventuality of a flu pandemic and are providing support and co-ordination."

Romania's Agriculture Minister, Gheorghe Flutur, said scientists had so far been unable to isolate the virus in the suspect birds, a fact which implied that the cause of the outbreak was unlikely to be a virulent strain.

Testing is complex because birds that have developed antibodies to avian flu at some point in their lives may not have contracted the disease.

Three birds that tested positive for bird flu on Saturday in the village of Smardan in fact did not die from it. "We reviewed the tests and it [bird flu] was not confirmed in them," Mr Flutur said.

With the situation remaining confused in Romania, the European Commission said it would send experts to Romania today to help to ascertain the situation there.

The Danube delta, on the Black Sea, contains Europe's largest wetlands, and is a major migratory area for wild birds coming from Russia, Scandinavia, Poland and Germany. The birds mainly move to warmer areas in North Africa, including the Nile delta, for winter.

Brussels is urging member states to prepare for the worst-case scenario, and to stockpile antiviral drugs and to generate more vaccines. The European Commission has limited powers, however, as the primary responsibility lies with EU member states.

The World Health Organisation warned last month that bird flu was moving towards a form that could be passed between humans, and the world had no time to waste to prevent a pandemic.

Europe was put on a continental alert for avian flu yesterday as Turkey and Romania culled hundreds of birds and quarantined villages after reported outbreaks in both countries.

Health officials across the continent increased surveillance for a strain of the disease that could mutate into one which spreads easily among humans. The so-called Spanish flu outbreakof 1918, which has been linked to the current strain, killed between 20 and 40 million people.

Romania has suffered suspicious bird deaths in seven locations and has slaughtered more than 1,000 animals. Turkey culled 2,000 chickens and turkeys after reporting its first outbreak of avian flu, which is commonly spread by migratory birds, on a farm near the Aegean Sea.

So far there have been no confirmed cases in Europe of the H5N1 strain of the virus, which has killed 65 people and millions of birds in Asia since 2003. Romania is still conducting tests, and the European Commission said that no cases of avian flu had yet been formally confirmed there.

Two years ago, an outbreak in the Netherlands led to the cull of 30 million birds. Health officials there have only recently lifted the most draconian restrictions designed to prevent contact with migrating birds.

In Europe there is growing concern at the lack of preparedness across the continent for a pandemic if the H5N1 strain arrives. Last week the Council of Europe Parliamentary Assembly said there was a "flagrant lack" of vaccines and anti-viral medicines to combat a pandemic. It said that the countries most at risk were facing the pandemic alone, "without the necessary financial resources to buy anti-viral vaccines and medicines to build up adequate stocks".

In Turkey the Hurriyet newspaper said that up to 16,000 animals would be slaughtered and that the affected district of Kiziksa will remain under quarantine for 21 days. Stray dogs in the area were being killed as a precaution.

Officials say the infected turkeys in Kiziksa probably contracted the disease from migratory birds from the Ural mountains heading for a nearby natural park called Bird Paradise.

Hurriyet reported that Mehmet Eksen, owner of the stricken Turkish farm, feared for his own health. The paper quoted him as saying: "I cried when I witnessed the death of my turkeys. I cannot forget those moments ... But now I think of myself and what will happen to my health. I cannot go near my wife and children."
In Brussels, Philip Tod, spokesman for the European Commission, said: " We are in a heightened state of vigilance. We have surveillance measures in place for poultry and wild birds. All member states are carrying out surveillance jointly financed with the EU.

"Member states have been asked to increase border inspections on live birds and poultry and we have instructed them to increase hygiene measures.

"These measures were taken as a response to the spread of avian flue to Siberia and Kazakhstan.

"We are working with the member states to prepare for the eventuality of a flu pandemic and are providing support and co-ordination."

Romania's Agriculture Minister, Gheorghe Flutur, said scientists had so far been unable to isolate the virus in the suspect birds, a fact which implied that the cause of the outbreak was unlikely to be a virulent strain.

Testing is complex because birds that have developed antibodies to avian flu at some point in their lives may not have contracted the disease.

Three birds that tested positive for bird flu on Saturday in the village of Smardan in fact did not die from it. "We reviewed the tests and it [bird flu] was not confirmed in them," Mr Flutur said.

With the situation remaining confused in Romania, the European Commission said it would send experts to Romania today to help to ascertain the situation there.

The Danube delta, on the Black Sea, contains Europe's largest wetlands, and is a major migratory area for wild birds coming from Russia, Scandinavia, Poland and Germany. The birds mainly move to warmer areas in North Africa, including the Nile delta, for winter.

Brussels is urging member states to prepare for the worst-case scenario, and to stockpile antiviral drugs and to generate more vaccines. The European Commission has limited powers, however, as the primary responsibility lies with EU member states.

The World Health Organisation warned last month that bird flu was moving towards a form that could be passed between humans, and the world had no time to waste to prevent a pandemic.
 
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<B><center><font size=+1 color=blue>Hungary bans Romanian meat on bird flu fears</font>

10.10.05 12.20pm
<A href="http://www.nzherald.co.nz/section/story.cfm?c_id=2&ObjectID=10349527">NZheral.nz.com</A>
BUDAPEST - Hungary has banned the import of poultry meat, livestock and all related products from neighbouring Romania because of fears of bird flu, chief veterinarian Miklos Suth told the state news agency MTI on Sunday.</B></center>
Romania culled hundreds of birds and quarantined villages to try to halt the spread of bird flu after it was detected in poultry in its Danube delta.

Hungary's ban comes after several other European Union countries, including Austria and Poland, implemented similar bans, MTI said.

Turkish and Romanian authorities culled thousands of birds and imposed quarantine zones on Sunday to try to stop the spread of avian disease.

Romania's suspected outbreak was detected in poultry in the Danube delta on the Black Sea. The European Commission says the Romanian and Turkish cases are different but they have raised the spectre of the disease reaching European Union countries.

If the Romanian cases did turn out to be the deadly H5N1 virus, they would be the first evidence the strain has spread to Europe from Asia, where it has killed more than 60 people and millions of birds since 2003. Hungary's health authorities have called for an emergency meeting for Monday to stop bird flu.

- REUTERS
 
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<B><font size=+1 color=green><center>Vaccine failure could lead to flu pandemic</font>

Robin McKie, science editor
Sunday October 9, 2005
<A href="http://society.guardian.co.uk/health/news/0,8363,1588751,00.html">The Observer </A>

Prospects of providing protection against the expected global outbreak of avian flu have been dashed by US researchers. They have found that only massive doses of vaccine are likely to protect individuals against the disease. As a result, manufacturing plants would strain to make even meagre supplies for a small number of people, doctors have warned.</B></center>
'There is now a tremendous anxiety among scientists - including me - about this,' said bioprocessing expert Professor Peter Dunnill, chairman of the Advanced Centre for Biochemical Engineering at University College, London. 'Instead of providing protection for up to a billion people across the world, we will be lucky to get enough doses to vaccinate a few dozen million.

'That is not going to halt this virus if it gets into the human population. The problem is that the science of vaccines is great but the technology for their manufacture is lousy.'

At present, millions of chickens and other poultry are known to be infected with a deadly strain of flu virus known as H5N1. People who have picked up the virus from these birds have become seriously ill and in some cases have died. Doctors and scientists now fear a version that could be passed from human to human could soon evolve from avian H5N1. The result would be a deadly flu pandemic, one that would rival the 1918 outbreak of the disease which killed more than 20 million people.

Two medicines have been put forward as key defences against the outbreak. The first, the anti-viral medicine Tamiflu, which blocks the flu virus's growth within the body, could protect key workers - doctors, nurses, transport staff and police - when the disease strikes Britain. Supplies of Tamiflu are limited, however.

Instead, the main line of defence would be to rely on injecting people with a vaccine - based on a crippled version of the H5N1 virus - to boost immune defences in preparation of future infection.

But a new study by the National Institute of Allergy and Infectious Disease in Bethesda, Maryland, has dashed these prospects. Scientists at the institute used a vaccine made to combat the H5N1 avian flu virus and tested various concentrations on 452 healthy adults.

Only those who received the maximum dose - two shots of 90 micrograms of vaccine - were protected. 'This is the worst-case scenario,' James Robertson, of the UK National Institutes for Biological Standards and Control, told Nature. 'You are not going to get far with that.'

At present, the world has the capacity to manufacture about 900 million doses of flu vaccine a year at drug plants round the globe. But these vaccines are designed to target existing flu strains. Only a single dose of 15 micrograms is required for these.

Professor Ian Jones, of Reading University said: 'It is possible we could improve dosage levels but legal disputes over manufacturing rights, problems of scaling up manufacturing, arguments about who owns vaccines made in a given country and many other problems will also affect vaccine manufacture. We will be lucky to get enough vaccine to protect the public against avian flu in the next five years. We should therefore be quite clear: the chances of stopping a flu pandemic before 2010 are going to be extremely slim.'

Scientists do however point out that a human version of H5N1 could still fail to emerge. The virus could remain isolated in bird populations, weakening over the years until it poses no risk to humanity. 'It is a possibility but do we want to do nothing and hope for the best given the stakes?' added Jones.

Instead, scientists are now pressing that more radical solutions be sought. 'The current vaccine system is not going to work,' said Dunnill. 'We need a new approach.'
 
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<B><font size=+1 color=purple><center>Romania records more suspected flu deaths in birds</font>
10 Oct 2005 10:23:37 GMT

<A href="http://www.alertnet.org/thenews/newsdesk/L10728879.htm">Reuters AlertNet.com</A>

BUCHAREST, Oct 10 (Reuters) - More suspected outbreaks of bird flu occurred in Romania in the Danube delta on Monday as scientists tested to see whether they were dealing with the feared H5N1 strain that has killed people in Asia.</B></center>
Private television station Realitatea TV reported that dozens of birds, including swans and poultry, had been found dead in the village of Maliuc in the delta on Monday.

Officials have said that up to 1,000 birds might have died in Romania's delta, on the Black Sea, over the past days.

"Currently we're doing tests on around 300 birds that died suspiciously in the Delta over the past couple of days," the country's chief veterinarian Ion Agafitei told Reuters. "The tests are in different stages."

Agafitei said the three ducks tested positive for bird flu on Friday, Romania's first cases ever, remain the only ones where antibodies for the disease have been detected so far.

He confirmed that a team of British experts would arrive later in the day to help the local scientists isolate the virus and take relevant samples from the ducks to Britain to discover whether it is the H5N1 strain.

If the Romanian cases did turn out to be H5N1, they would be the first evidence the virus had spread to Europe from Asia, where it has killed 65 people and millions of birds since 2003.

Agriculture Minister Gheorghe Flutur said on Sunday scientists had been unable to isolate the virus in the suspect birds, indicating it was less likely to be a virulent strain.

The Danube delta contains Europe's largest wetlands and is a major migratory area for wild birds coming from Russia, Scandinavia, Poland and Germany.
 
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<B><center>*BUMP*</B></center>

Some one might consider on helping to keep this thread on the front page - by bumping it (Pretty Please).

Or else, it will go to the infectious thread forum that much sooner...
 

Ironhand

Inactive
This earthquake can't be good news for those people trying to figure out how to fight a pandemic.

Is it me, or does there seem to be a larger number of infected people the past week or so?

Thanks for your research Shakey.
 

janswizard

Inactive
I have a question (and will help to keep this on the front page, as well.) From one of the above articles, it states "Hungary has banned the import of poultry meat, livestock and all related products from neighbouring Romania because of fears of bird flu, chief veterinarian Miklos Suth told the state news agency MTI on Sunday". Has there been any documentation that this virus will spread to livestock other than poultry meat? I'm concerned that if this is so, would our domestic animals (cats and dogs) be susceptible to this virus as well?
 

Firebird

Has No Life - Lives on TB
WOW! Thanks for the info Shakey. Just finished listening to Alex Jones today and he talked extensively about the bird flu. This stuff is really coming on fast :shkr:
 

LMonty911

Deceased
janswizard- there have been scattered reports of H5N1 infections in both dogs and cats. its currently unknown if the eventual pandemic strain will be efficienly transmitted between domestic animals and people
 

Mrs. Peavey

Membership Revoked
I have a question too.................

Many people in the U.S. have a small flock of chickens and/or other poultry. DH and I have always had chickens for egg production.

Scary part is that last year we had a whole flock of young chickens die, and we don't know what they died from. Obviously it wasn't avian flu, as we're still here to tell about it. We started over, purchasing day-old chicks from a different hatchery and had them vaccinated for the most common chicken diseases.

Although there's been no reports of avian flu affecting chickens in the U.S., it would be a good idea to know what to look for. Does anyone know what sort of symptoms a chicken displays if it's got avian flu?
 

duchess47

Has No Life - Lives on TB
Although there's been no reports of avian flu affecting chickens in the U.S., it would be a good idea to know what to look for. Does anyone know what sort of symptoms a chicken displays if it's got avian flu?

I'm not sure about that and think you might want to do a search. Seems I read about some chickens with the avian flu here in the states - last year? year before?
 

freebyrd

Membership Revoked
Alex Jones today and he talked extensively about the bird flu.
warning alex jones is a psycological meme around here for many people,
if you stated that alex jones was on the radio today talking about the assasination of president lincoln, some people would fall all over themselves denying it ever happened, because alex a is spreader of lies,
funny thing is half the posts i see on this and many boards are old news to me because i listen to alex. truth is he's on the cutting edge,
sorry about the thread drift,

bird flu......bad....there you go
freebyrd
 

learningcurve

Contributing Member
This is what they are willing to admit.

The bird flu was at the bottom of my list of concerns, but it moved up quickly. At this point the US administration seems to be engaged in a PR effort. If this hits soon they can say, "We did all we could, but who knew a pandemic could strike in America?"
 
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