[HLTH/WOT] Birds may carry/spread Ebola virus

Deb Mc

Veteran Member
Purdue Research Hints That Birds Could Spread Ebola Virus

Source: Purdue University
Date: 12/17/2002


WEST LAFAYETTE, Ind. -- Ebola shares a closer relationship with several bird viruses than was previously thought, bolstering the case for a common ancestor and hinting that birds might carry the deadly virus, a Purdue University research team reports.

David Sanders and his research group have discovered that the outer protein shell of Ebola has a biochemical structure similar to several retroviruses carried by birds. As scientists had known previously of genetic similarity among the viruses, this discovery makes a common evolutionary origin even more likely. It also suggests that Ebola could be spread to human populations by birds as well.

"We knew these viruses were inwardly similar, and now we see their outer similarity as well," said Sanders, associate professor of biological sciences in Purdue's School of Science. "While bird transmission of Ebola is by no means certain, the resemblance among all these viruses should encourage health officials to be on guard for it."

The research appears in Sunday's (12/15) Journal of Virology. Two contributors to the group's research are Scott Jeffers, a graduate student in Sanders' laboratory, and Anthony Sanchez, an Ebola virus expert at the Centers for Disease Control.

Since its discovery in 1976, Ebola has been responsible for hundreds of deaths in central Africa. Though the source of the virus in nature remains unknown, both humans and monkeys appear susceptible. Death rates of between 50 percent and 90 percent are common during outbreaks.

"Ebola is one of the viruses with which the U.S. agencies in charge of biodefense are most concerned," Sanders said. "Identification of its natural hosts should be a priority."

This research was sponsored by the Cystic Fibrosis Foundation and the Purdue Research Foundation.

Note: This story has been adapted from a news release issued for journalists and other members of the public. If you wish to quote any part of this story, please credit Purdue University as the original source. You may also wish to include the following link in any citation:

http://www.sciencedaily.com/releases/2002/12/021217072529.htm
 

Pineapple

Membership Revoked
Thats a good question Kris. They didn't mention how the bird would pass it to humans, unless they are meaning via/ mosquitos like west nile.

However, I would think that if Ebola could be spread by mosquitos, the rate of ebola infections in Africa, etc. would be MUCH higher.

Maybe you have to eat an infected bird or something like that?
 

ittybit

Inactive
A bit here, and a bit there...pretty soon you have a WMD, huh?

Yeah.

WNV may be a trial or it may be a typical 'accident'. Either way it can be studied and info used.

Hope we aren't so cleaver as to have gotten our mitts on this one.

..
 

dabom

Veteran Member
[HLTH] Ebola 'could be spread by birds'

http://news.bbc.co.uk/2/hi/health/2584335.stm

Ebola 'could be
spread by birds'

Ebola has killed hundreds of people in central Africa
There are fears that birds could
spread the deadly Ebola virus.

The shell of the human pathogen is
similar to viruses that attack birds,
suggesting it could have jumped from
birds to humans.

If this is the case,
Ebola could be
being carried long
distances on the
wing, with obvious
health implications.

The theory has not been proven, but
researchers say it should be borne in
mind by health agencies.

The warning comes from US
researchers who have studied the
biochemical structure of Ebola.

David Sanders of
Purdue University
in West
Lafayette,
Indiana, said
biochemical
analysis revealed
the protein shell
of Ebola was close
to that of certain
bird retroviruses.

A genetic
similarity between
Ebola and several bird viruses has
already been noted.

Taken together, it suggests Ebola
was once a bird virus and could now
be being spread by birds.

"We knew these viruses were
inwardly similar, and now we see
their outer similarity as well," he
said.

"While bird transmission of Ebola is
by no means certain, the resemblance
among all these viruses should
encourage health officials to be on
guard for it."

Migratory birds

Ebola, which was discovered in 1976,
is known to infect humans and
monkeys.

It has lead to hundreds of deaths in
central Africa, and it is fatal in 50 to
90% of cases.

Traces of the virus have also been
discovered in small mammals,
suggesting they may help spread the
disease although they cannot catch
it.

Health officials are keen to find out
how Ebola gets to people, to help in
the fight against the deadly disease.

"It is possible that there is a bird
host, possibly a migratory bird, and
that is consistent with the
epidemiology of the disease,"
Professor Sanders told BBC News
Online.

"We haven't found any birds infected
by the Ebola virus yet," he added.
"But birds haven't been examined."

Gene therapy

The Purdue research is reported in
the Journal of Virology.

The scientists reveal in the same
journal that they have been able to
redesign the shell of the virus to
transform it from killer to healer.

They say the modified virus could be
used as a vehicle for gene therapy.

It has been developed into a form
that could be inhaled rather than
injected, which may one day be
helpful in treating lung diseases such
as cystic fibrosis.
 

Maiden

Membership Revoked
"We haven't found any birds infected by the Ebola virus yet," he added. "But birds haven't been examined."

What are they waiting for?! This is really serious! :eek:

I wonder what areas these birds are in that are suspected carriers of Ebola as it would certainly affect myself and others in taking in injured and orphaned adult and baby wildlife birds for rehabilitation due to contamination.

Perhaps it is mentioned in the article and I just missed it? :confused: I will go and read this again right now!
 

CanadaSue

Membership Revoked
Weird...

Can't find my copy of The Hot Zone, but it seems to me that every concievable form of life that could be tested for Ebola/Marburg had been trapped & tested in various parts of Africa where it appears to be endemic. If birds weren't done, that seems a very serious omission. It would usually imply an insect vector, yet no insects have been shown to carry it, unless the cycle of host/vecto/victim is infinitely more complicated than we've so far considered. I pesonally doubt that; viruses tens to be fairly simple entities. But we've been surprised before, right?

But anyway, if birds were hosts, I'd expect the disease to be endemic over a wider area & make more frequent appearances. It's possible though, that the virus, through some yet to be understood mechanism, "needs" very specific conditions to spread to a vector, is extremely short lived in that vector & thus we see it rarely. I'd like to think that factors such as weather conditions, (remember Hanta?), movement of animals/bords/people, etc are being considered & any co-relations noted.

FWIW, based on absolutely nothing at all, no knowledge, no discernable pattern... I think we're about to see another outbreak of Ebola in Africa - another big one with cases numbering in the high hundreds.
 
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