bw
Fringe Ranger
1: If this is jab-dependent, the PTB weren't jabbed and aren't at risk.
2: The highest PTB who are orchestrating this have rings of people between them and the petri dish.
CORONA Boston University CREATES a new Covid strain that has an 80% kill rate — echoing dangerous experiments feared to have started pandemic
- Thread starter somewherepress
- Start date
2: The highest PTB who are orchestrating this have rings of people between them and the petri dish.
Or most likely, when are they going to have the "accidental" release of this virus? That will be their test.
bw
Fringe Ranger
So far mice. The human trials will be conducted the same as the WuFlu trials.
Mprepared
Veteran Member
Delete.
Last edited:
jward
passin' thru
Boston University CREATES new Omicron strain that has an 80% kill rate
The variant - which is a hybrid of Omicron and the original Wuhan virus - killed 80 per cent of mice infected with it at Boston University.www.dailymail.co.uk
Boston University CREATES a new Covid strain that has an 80% kill rate — echoing dangerous experiments feared to have started pandemic
| Prof Francois Balloux @BallouxFrancois Director @UGI_at_UCL Interest in Infectious disease epidemiology, genomics and global health Where snow is powdery and deepscholar.google.co.uk/citations?user… Joined April 2019 1,038 Following 149.2K Followers |
This article is not incorrect but it lacks some context. Researchers created a chimeric virus with a BA.1 Omicron Spike protein within a 'Wuhan' early pandemic backbone. The chimera killed ~80% infected mice, Omicron none, but the 'non-chimeric Wuhan strain' killed 100% mice.
1/
Thus, the chimeric virus was far more virulent than Omicron in mice, but probably less so than early pandemic strains. It also confirms - something we suspected - that the reduced virulence of Omicron lineages is not only due to mutations in the Spike protein.
2/
Omicron-Wuhan recombinants are unlikely to create super-lethal strains in humans. We know of several natural Omicron-Delta recombinants with the XD and XAW lineages having a BA.1 and BA.2 Spike protein within a Delta genomic backbone, respectively. Those lineages are gone now.
3/
To summarise, this study doesn't report a 'super-lethal' strain and similar chimeric viral strains (with a Delta rather than a Wuhan backbone) emerged naturally and have been in circulation at low frequency for a while.
4/
I'm not implying studies such as this one, using 'live' chimeric viruses should be performed as the risk / benefit balance generally doesn't feel overly convincing to me. This being said, this specific study is not as worrying as might seem at first.
5/
I anticipate the controversy around engineered chimeric live viruses will heat up further in the future, and I'd be surprised if we didn't end up with an outright ban on such lab experiments in the end.
6/
Link to the preprint:
7/
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron The recently identified, globally predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major v… Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron
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Walkin' Away
Senior Member
Mr. Bill said the “next one” will get your attention.
Dear TB2K Family…pay attention to this one and prepare for the Dark Winter that we were threatened with by our resident liar-in-chief previously.
As many have said above, there are too many who are not going along with the plan…and the peasants cannot be allowed to throw off the chains…
Stay Healthy and Stay Close to God.
W. A.
Dear TB2K Family…pay attention to this one and prepare for the Dark Winter that we were threatened with by our resident liar-in-chief previously.
As many have said above, there are too many who are not going along with the plan…and the peasants cannot be allowed to throw off the chains…
Stay Healthy and Stay Close to God.
W. A.
jward
passin' thru
New Results Follow this preprint
The recently identified, globally predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major viral variants recognized to date1–7. The Omicron spike (S) protein, with an unusually large number of mutations, is considered the major driver of these phenotypes3,8. We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant. The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. In K18-hACE2 mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. This indicates that while the vaccine escape of Omicron is defined by mutations in S, major determinants of viral pathogenicity reside outside of S.
Competing Interest Statement
The authors have declared no competing interest.
www.biorxiv.org
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron
AbstractThe recently identified, globally predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major viral variants recognized to date1–7. The Omicron spike (S) protein, with an unusually large number of mutations, is considered the major driver of these phenotypes3,8. We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant. The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. In K18-hACE2 mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. This indicates that while the vaccine escape of Omicron is defined by mutations in S, major determinants of viral pathogenicity reside outside of S.
Competing Interest Statement
The authors have declared no competing interest.
Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron
The recently identified, globally predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major viral variants recognized to date[1][1]–[7][2]. The Omicron spike (S) protein, with an unusually...
www.biorxiv.org
wobble
Veteran Member
Let's make some more deadly strains and then promote more vaccinations.
packyderms_wife
Neither here nor there.
pretty much!
rhughe13
Heart of Dixie
The vaccines were probably ready to ship before the article came out.
pauldingbabe
The Great Cat
Ok, come on WIZARDS OF SMART, throw us a bone here and explain this s*** away. I’m ready for the third time this year -an all time generational high score- to see the cup half full. I’ll take any of your COVID convoluted explanations using SCIENCE AT THE SPEED OF LIGHT to help me sleep at night…..
The original strain hasn't been captured and replicated so all this I'd bullshit and nonsense?
Don't have a quote for it but that's what I read on Twitter.
Don't kill the messenger.
Wyominglarry
Veteran Member
What could possibility go wrong?
psychgirl
Has No Life - Lives on TB
That’s MY question!
pauldingbabe
The Great Cat
Africa....with your tax dollars
Josie
Has No Life - Lives on TB
And keep in mind that this is only ONE lab admitting to this. How many more are there that we don't know about? Just because you can, doesn't mean you should.
See now, my mind went in a totally different direction. If it does indeed take out the vaxxed, and the ultimate goal is population reduction, why would you think that you are safe if you didn't get jabbed? Could there be a little something "extra" in this Frankenstein's monster just for everyone that did not comply?
But see, there are no guarantees here. Viruses are opportunistic creatures. With each generation, they mutate to adapt to their surroundings to be a more efficient at infecting. So with each "ring" a virus will change and may not resemble the original. Any "surefire" antidote in the beginning probably won't be so surefire by the time the virus has reached the inner circle.
This is why I really don't believe that being unvaxxed is a protection in this instance.
Samuel Adams
Has No Life - Lives on TB
Why did they even “release the data” ?
Groucho
Has No Life - Lives on TB
et2
Has No Life - Lives on TB
Count on it
155 arty
Veteran Member
how is this gain of function research alowed ???
Boston University CREATES new Omicron strain that has an 80% kill rate
The variant - which is a hybrid of Omicron and the original Wuhan virus - killed 80 per cent of mice infected with it at Boston University.Boston University CREATES a new Covid strain that has an 80% kill rate — echoing dangerous experiments feared to have started pandemic
By CAITLIN TILLEY, HEALTH REPORTER FOR DAILYMAIL.COM
- Researchers added Omicron's spike protein to the original Wuhan Covid strain
- Omicron's spike is highly mutated which made it the most infectious variant ever
- Eight in 10 mice infected with the lab-created strain died at Boston University lab
PUBLISHED: 11:02 EDT, 17 October 2022 | UPDATED: 13:04 EDT, 17 October 2022
US researchers have developed a new lethal Covid strain in a laboratory – echoing the type of experiments many fear started the pandemic.
The mutant variant — which is a hybrid of Omicron and the original Wuhan virus — killed 80 percent of mice infected with it at Boston University.
When a similar group of rodents were exposed to the standard Omicron strain, however, they all survived and only experienced 'mild' symptoms.
ADVERTISEMENT
The scientists also infected human cells with the hybrid variant and found it was five times more infectious than Omicron.
This suggests the man-made virus might be the most contagious form yet.
It will no doubt surprise many Americans that such experiments continue to go on in the US despite concerns similar studies may have led to the global Covid outbreak.
Covid first began spreading from a wet market in Wuhan, China, about eight miles from a similar high-security virology laboratory that manipulated bat coronaviruses.
Chinese scientists were found to have wiped crucial databases and stifled independent investigations into the facility's links to the pandemic.
+10
View gallery
In the new research , which has not been peer-reviewed, a team of researchers from Boston and Florida extracted Omicron's spike protein — the unique structure that binds to and invades human cells. It has always been present but it has become more evolved over time. Omicron has dozens of mutations in its spike protein that made it so infectious. Researchers attached Omicron's spike protein to the original wildtype strain that first emerged in Wuhan at the start of the pandemic. The researchers looked at how mice fared under the new
80 percent of mice died from the new man-made Covid strain, while none died from the milder Omicron variant alone, researchers at Boston University's National Emerging Infectious Diseases Laboratories found
In the new research, which has not been peer-reviewed, a team of researchers from Boston and Florida extracted Omicron's spike protein — the unique structure that binds to and invades human cells.
It has always been present in the virus but has become more evolved over time. Omicron has dozens of mutations on its spike protein that made it so infectious.
Researchers attached Omicron's spike to the original wildtype strain that first emerged in Wuhan at the start of the pandemic.
The researchers looked at how mice fared against the new hybrid strain compared to the original Omicron variant.
Writing in the paper, they said: ‘In...mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80 percent.’
The researchers said it signaled that while the spike protein is responsible for infectivity, changes to other parts of its structure determine its deadliness.
The question of whether the global outbreak began with a spillover from wildlife sold at the market or leaked out of the Wuhan lab just eight miles across the Yangtze River has given rise to fierce debate about how to prevent the next pandemic. New studies point to a natural spillover at the Huanan wildlife market. Positive swab samples of floors, cages and counters also track the virus back to stalls in the southwestern corner of the market (bottom left), where animals with the potential to harbor Covid were sold for meat or fur at the time (bott
Covid latches onto human cells with its spike protein, and instructs produce copies of itself.
Scientists measured how many copies each variant caused the health cells to produce.
They found the hybrid strain produced five times more viral particles than the original Omicron.
The scientists admit the hybrid virus is unlikely to be as deadly in humans as it was in mice.
This is because the specific breed of lab mice used are very susceptible to severe Covid disease. Mice and humans also have very different immune responses to the virus.
The lab, at Boston University's National Emerging Infectious Diseases Laboratories, is one of 13 biosafety level 4 labs in the US.
These are labs that are authorized to handle the most dangerous pathogens. There are also facilities in Texas, Atlanta and Manhattan, Kansas.
Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.
Work on the live virus that causes Covid must be carried out at a BSL-3 or BSL-4 lab.
In BSL-3 labs, researchers do all experiments in a ‘biosafety cabinet’ — an enclosed, ventilated workspace for handling materials contaminated with pathogens.
The labs also have self-closing doors, sealed windows, floors and walls, and filtered ventilation systems.
In a BSL-4 lab, full-body, air-supplied pressure suits are worn and workers must change their clothing before entering and shower before leaving.
The lab is situated in a separate section of the building and has its own dedicated air supply.
The 'lab leak' origin theory for Covid was initially dismissed as conspiracy at the start of the pandemic in favour of a natural emergence.
But the hypothesis gained momentum following a series of revelations and cover-ups.
Crucial information about the earliest infected patients was wiped from the Wuhan lab's database in late 2019 and one of its staff vanished after coming down with a mysterious flu-like illness.
Have we learned nothing? 40 new biochemical labs that handle dangerous viruses are being built around the world
The Coronavirus pandemic has prompted a global surge in laboratories that handle dangerous viruses — despite concerns Covid may have been the result of the risky experiments.
More than 40 facilities certified as biosafety level 3 (BSL-3) or BSL-4 have either been built or have gone into construction since 2020, predominantly across Asia.
Many countries believe they were caught flat-footed by Covid and want to get ahead of the next devastating outbreak by studying pathogens that pose a threat to humans.
Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.
+10
View gallery
There are currently 63 BSL-4 labs, the highest level of security, across the globe. This is up from the 59 which were in operation or planned last year. Three-quarters are in urban areas. South America and Africa are some of the places lacking access to the labs
But there are widespread concerns that these experiments might actually raise the risk of pandemics — something some experts believe was the case with Covid.
The virus first began spreading from a wet market in Wuhan, about eight miles from the Wuhan Institute of Virology (WIV), a high security biolab that worked with dangerous bat coronaviruses.
Scientists there worked on some of Covid's closest relatives. They were also found to have wiped crucial databases and stifled independent investigations into the laboratory's links to the pandemic.
Professor Paul Hunter, an expert in infection diseases at the University of East Anglia in England, told DailyMail.com he was concerned about what all the new labs would be used for.
'The issue is what you’re going to be using [the labs] for,' he told this website. 'If they’re for diagnostic purposes, then you need them. But I don’t think every country needs a BSL-4.’
He added: ‘If they start having a dual purpose for research that has offensive military implications, that is the concern.’
Russia has set out its proposals for 15 of the maximum security labs and India is aiming for 18 BSL-3 and BSL-4 labs in total. The US is also adding a further highest level biosecurity lab to its existing 12.
Bps1691
Veteran Member
Proving once again that university academics have shit for brains when it comes to the real world consequences of the research they do.
Those that are part of this should lose their jobs and be black listed throughout this country.
If they used any federal grant money for this dangerous work they broke the rules and possibly laws for doing enhancement work on known disease organisms.
Those that are part of this should lose their jobs and be black listed throughout this country.
If they used any federal grant money for this dangerous work they broke the rules and possibly laws for doing enhancement work on known disease organisms.
Nothing "cures" it.
The Big Guy's 10% ...
bracketquant
Veteran Member
4 out of 5 doctors recommend...
...well, they don't recommend anything, they're dead.
...well, they don't recommend anything, they're dead.
Buick Electra
TB2K Girls with Guns
somewherepress
Has No Life - Lives on TB
Nothing cures stupidity either. Even the gov has authorized IVM for treatment of covid.
View: https://twitter.com/AurelianofRome/status/1582132682493861889
bracketquant
Veteran Member
Samuel Adams
Has No Life - Lives on TB
Same way something as sacred and crucial to a representative free republic as an honest election can be abandoned by the constituency.
Easily.
What's there to worry about? Hasn't everybody taken the 10 shots and 20 boosters?
Boston University CREATES new Omicron strain that has an 80% kill rate
The variant - which is a hybrid of Omicron and the original Wuhan virus - killed 80 per cent of mice infected with it at Boston University.Boston University CREATES a new Covid strain that has an 80% kill rate — echoing dangerous experiments feared to have started pandemic
By CAITLIN TILLEY, HEALTH REPORTER FOR DAILYMAIL.COM
- Researchers added Omicron's spike protein to the original Wuhan Covid strain
- Omicron's spike is highly mutated which made it the most infectious variant ever
- Eight in 10 mice infected with the lab-created strain died at Boston University lab
PUBLISHED: 11:02 EDT, 17 October 2022 | UPDATED: 13:04 EDT, 17 October 2022
US researchers have developed a new lethal Covid strain in a laboratory – echoing the type of experiments many fear started the pandemic.
The mutant variant — which is a hybrid of Omicron and the original Wuhan virus — killed 80 percent of mice infected with it at Boston University.
When a similar group of rodents were exposed to the standard Omicron strain, however, they all survived and only experienced 'mild' symptoms.
ADVERTISEMENT
The scientists also infected human cells with the hybrid variant and found it was five times more infectious than Omicron.
This suggests the man-made virus might be the most contagious form yet.
It will no doubt surprise many Americans that such experiments continue to go on in the US despite concerns similar studies may have led to the global Covid outbreak.
Covid first began spreading from a wet market in Wuhan, China, about eight miles from a similar high-security virology laboratory that manipulated bat coronaviruses.
Chinese scientists were found to have wiped crucial databases and stifled independent investigations into the facility's links to the pandemic.
+10
View gallery
In the new research , which has not been peer-reviewed, a team of researchers from Boston and Florida extracted Omicron's spike protein — the unique structure that binds to and invades human cells. It has always been present but it has become more evolved over time. Omicron has dozens of mutations in its spike protein that made it so infectious. Researchers attached Omicron's spike protein to the original wildtype strain that first emerged in Wuhan at the start of the pandemic. The researchers looked at how mice fared under the new
80 percent of mice died from the new man-made Covid strain, while none died from the milder Omicron variant alone, researchers at Boston University's National Emerging Infectious Diseases Laboratories found
In the new research, which has not been peer-reviewed, a team of researchers from Boston and Florida extracted Omicron's spike protein — the unique structure that binds to and invades human cells.
It has always been present in the virus but has become more evolved over time. Omicron has dozens of mutations on its spike protein that made it so infectious.
Researchers attached Omicron's spike to the original wildtype strain that first emerged in Wuhan at the start of the pandemic.
The researchers looked at how mice fared against the new hybrid strain compared to the original Omicron variant.
Writing in the paper, they said: ‘In...mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80 percent.’
The researchers said it signaled that while the spike protein is responsible for infectivity, changes to other parts of its structure determine its deadliness.
The question of whether the global outbreak began with a spillover from wildlife sold at the market or leaked out of the Wuhan lab just eight miles across the Yangtze River has given rise to fierce debate about how to prevent the next pandemic. New studies point to a natural spillover at the Huanan wildlife market. Positive swab samples of floors, cages and counters also track the virus back to stalls in the southwestern corner of the market (bottom left), where animals with the potential to harbor Covid were sold for meat or fur at the time (bott
Covid latches onto human cells with its spike protein, and instructs produce copies of itself.
Scientists measured how many copies each variant caused the health cells to produce.
They found the hybrid strain produced five times more viral particles than the original Omicron.
The scientists admit the hybrid virus is unlikely to be as deadly in humans as it was in mice.
This is because the specific breed of lab mice used are very susceptible to severe Covid disease. Mice and humans also have very different immune responses to the virus.
The lab, at Boston University's National Emerging Infectious Diseases Laboratories, is one of 13 biosafety level 4 labs in the US.
These are labs that are authorized to handle the most dangerous pathogens. There are also facilities in Texas, Atlanta and Manhattan, Kansas.
Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.
Work on the live virus that causes Covid must be carried out at a BSL-3 or BSL-4 lab.
In BSL-3 labs, researchers do all experiments in a ‘biosafety cabinet’ — an enclosed, ventilated workspace for handling materials contaminated with pathogens.
The labs also have self-closing doors, sealed windows, floors and walls, and filtered ventilation systems.
In a BSL-4 lab, full-body, air-supplied pressure suits are worn and workers must change their clothing before entering and shower before leaving.
The lab is situated in a separate section of the building and has its own dedicated air supply.
The 'lab leak' origin theory for Covid was initially dismissed as conspiracy at the start of the pandemic in favour of a natural emergence.
But the hypothesis gained momentum following a series of revelations and cover-ups.
Crucial information about the earliest infected patients was wiped from the Wuhan lab's database in late 2019 and one of its staff vanished after coming down with a mysterious flu-like illness.
Have we learned nothing? 40 new biochemical labs that handle dangerous viruses are being built around the world
The Coronavirus pandemic has prompted a global surge in laboratories that handle dangerous viruses — despite concerns Covid may have been the result of the risky experiments.
More than 40 facilities certified as biosafety level 3 (BSL-3) or BSL-4 have either been built or have gone into construction since 2020, predominantly across Asia.
Many countries believe they were caught flat-footed by Covid and want to get ahead of the next devastating outbreak by studying pathogens that pose a threat to humans.
Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.
+10
View gallery
There are currently 63 BSL-4 labs, the highest level of security, across the globe. This is up from the 59 which were in operation or planned last year. Three-quarters are in urban areas. South America and Africa are some of the places lacking access to the labs
But there are widespread concerns that these experiments might actually raise the risk of pandemics — something some experts believe was the case with Covid.
The virus first began spreading from a wet market in Wuhan, about eight miles from the Wuhan Institute of Virology (WIV), a high security biolab that worked with dangerous bat coronaviruses.
Scientists there worked on some of Covid's closest relatives. They were also found to have wiped crucial databases and stifled independent investigations into the laboratory's links to the pandemic.
Professor Paul Hunter, an expert in infection diseases at the University of East Anglia in England, told DailyMail.com he was concerned about what all the new labs would be used for.
'The issue is what you’re going to be using [the labs] for,' he told this website. 'If they’re for diagnostic purposes, then you need them. But I don’t think every country needs a BSL-4.’
He added: ‘If they start having a dual purpose for research that has offensive military implications, that is the concern.’
Russia has set out its proposals for 15 of the maximum security labs and India is aiming for 18 BSL-3 and BSL-4 labs in total. The US is also adding a further highest level biosecurity lab to its existing 12.
People are concerned and asking intelligent questions.
Intestinal Fortitude never asked if Ivermectin and D would "cure it". He asked if they could stop it, which is a good question.
As usual, your snarky response missed the point, but you have demonstrated repeatedly that you take the .Gov side every time.
If you are not trolling, then you are the most un-self aware being that I have ever encountered.
somewherepress
Has No Life - Lives on TB
Actually, vaxxed are the ones who need to worry the most.
Countrymouse
Country exile in the city
Last edited: