HR Geiger and Scott Ridley touched on a different black goo:
Chemical A0-3959X.91 – 15, also known as Agent A0-3959X.91 – 15 and referred to colloquially as the "black goo", "black liquid" or "pathogen", was an extremely potent and virulent mutagenic pathogen, consisting of millions of small micro-organisms, that was manufactured by the alien species...
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"When organic species grow arrogant enough to travel the stars...They find it waiting. "Prometheus' cleansing fire." The fire that keeps the universe clean...Of parasites like you."
―Iris Humphries (from Alien: Bloodlines)
An analysis of Chemical A0-3959X.91 – 15.[1]
Chemical A0-3959X.91 – 15, also known as Agent A0-3959X.91 – 15[1] and referred to colloquially as the "black goo", "black liquid" or "pathogen", is an extremely potent and virulent mutagenic pathogen, composed of millions of small micro-organisms, that was manufactured by the Engineers, both to create life-forms and act as a biological weapon. Due to its volatile nature at ambient temperature, the Engineers housed the pathogen within Steatite Ampules. Those affected by the mutation were designated as Anathema[2] and were subject to various violent mutations.
Sometimes I have to wonder if the two do not have a connection...