6/16/07-6/22/07|Weekly Bird Flu Thread:HHS hears community leaders' ideas on pandemic

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HHS hears community leaders' ideas on pandemic readiness

http://www.cidrap.umn.edu/cidrap/content/influenza/panflu/news/jun1407summit.html

Lisa Schnirring * Staff Writer

Jun 14, 2007 (CIDRAP News) – A hundred leaders from the business, healthcare, faith, and civic communities met with US Department of Health and Human Services (HHS) officials yesterday to discuss how to motivate individuals and families to prepare for an influenza pandemic.

The Pandemic Influenza Leadership Forum in Washington, DC, was linked with an online effort by HHS to engage community leaders in talking about pandemic preparedness. On May 22 the agency launched a pandemic leadership blog, which continues through Jun 27, to stimulate discussions and public feedback. During the leadership forum, HHS employees "live blogged" the event, adding several detailed blog postings describing the presentations and breakout sessions.

HHS Secretary Mike Leavitt, in his address at the meeting, said the goal was to share ideas on how local leaders can promote the importance of personal preparedness, according to a transcript released by HHS.

Personal preparedness "is a message that needs to surround everyone. They need to hear it from their pastors, from their employers, from their physicians, and from everyone in a position of responsibility," Leavitt said. "And they need to keep hearing it. In fact, they need to hear it even more after the news media loses interest."

Despite uncertainty about when a pandemic will strike, Leavitt said, leaders can be sure of two things: "Everything we do before a pandemic will seem alarmist. Everything we do after a pandemic will seem inadequate."

"We need to reach out to everyone with words that inform, but not inflame. We need to encourage everyone to prepare, but not panic," Leavitt said.

At a press conference that followed the forum, Stephanie Marshall, director of pandemic communications for HHS, said the agency would launch two more personal-preparedness promotion efforts in the months ahead. Later this summer officials will release tool kits, tailored to four different sector (business, healthcare, faith, and civic), that leaders can use to teach people more about pandemic flu and what they can do to prepare.

Marshall told CIDRAP News that the forum yielded ideas that will help HHS tailor the tool kits for each sector. "We received a lot of thoughtful input yesterday," she said.

In the fall, HHS will target 5 to 10 diverse communities for more intensive communication campaigns about personal preparedness, Marshall said. "We certainly would like to include the appropriate representatives from the leadership forum and blog summit in these localized efforts," she added.

John Agwunobi, assistant secretary for health at HHS, said at the press conference that pandemic preparedness experts who share their expertise on the Internet and leaders representing other groups, such as churches, stand ready to help the government promote personal preparedness.

"They [pandemic planning leaders] need to be leveraged by the government and leaders, or at least listened to," he said. "I recognize that the federal government still has a lot to learn about the best way to engage individuals."

Greg Dworkin, MD, who took part in the leadership summit and is one of 13 experts who have led the blog discussions, told reporters he lauds the HHS for offering such an open live and online forum. The sometimes heated blog postings over the past weeks show there are many interested people who want good information from a federal source on individual and family preparedness, said Dworkin, founding editor of the FluWiki Web site and chief of pediatric pulmonology at Danbury Hospital in Danbury, Conn.

The HHS leadership forum helps validate the efforts of the many people who have already heeded pandemic warnings and started preparing their communities, their families, and themselves, he said.

According to an HHS news release yesterday, HHS officials at the meeting urged participants to communicate to their communities that it is critical for everyone to prepare for possible pandemic flu. Participants were urged to encourage people to(1) store extra food and other daily supplies to make it easier to stay home for a prolonged period of time, (2) learn and practice proper hand washing, (3) use safe cough and sneeze techniques to limit the spread of illnesses, and (4) stay home and avoid others during illness.

See also:

HHS Pandemic Flu Leadership Blog
http://blog.pandemicflu.gov/
 

JPD

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Move for bird flu-free status in two weeks

http://thestar.com.my/news/story.asp?file=/2007/6/16/nation/18041923&sec=nation

PETALING JAYA: If there are no more cases of the H5N1 virus in two weeks, Malaysia will submit a report to the World Health Organisation (WHO) and seek its approval to declare the country free of the avian flu.

“However, it is still up to WHO to process the report and scrutinise the findings before we can be truly considered H5N1 virus-free,” said Health Minister Datuk Seri Dr Chua Soi Lek.

He said the avian flu threat in Kampung Paya Jaras Hilir near here might have passed but the Government was taking no chances.

The ministry would continue to monitor the area, he told a press conference after opening the Malaysian Dental Association's annual general meeting yesterday.

The minister said there had been no reports in the past two days of residents falling ill or showing symptoms of cough or fever.

“This is definitely a very good sign. We will continue to monitor the area, especially within a 300m radius of the point of the virus’ origin,” he added.

“But in the meantime, all culling and case detection activities (door-to-door interviewing) have stopped.”

Dr Chua said it was important to now focus on the well-being of the 70 health and veterinary officers who had been at the village for the past week.

“They are undergoing medical check-ups to ensure they have a clean bill of health,” he said.
 

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Bird flu hits one more Vietnamese locality

http://news.xinhuanet.com/english/2007-06/16/content_6248633.htm

HANOI, June 16 (Xinhua) -- Bird flu has hit Vietnam's northern Cao Bang province, raising the total number of affected localities nationwide to 18 so far, according to a local veterinary agency on Saturday.

The disease killed 43 chickens and 44 ducks raised by a household in the province's Thong Nong district on June 11, the Department of Animal Health under the Ministry of Agriculture and Rural Development said, noting that specimens from the affected poultry have been tested positive to bird flu virus strain H5N1.

Bird flu, which started to strike Vietnam in December 2003, has hit 18 localities since early May.

To prevent the disease from further spreading, Vietnam is intensifying bird flu vaccination among poultry and tightening fowl trade, transport and production.

Vietnam has planned to import additional 500 million doses of bird flu vaccines for fowls, expected to be used in the 2007-2008 period.

The country has so far this year vaccinated 140.5 million fowls, including 81.6 million chickens, 55.45 million ducks and roughly 3.5 million white-winged ducks, said the department.
 

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Vietnam reports first bird flu death since 2005

http://www.abs-cbnnews.com/storypage.aspx?StoryId=81172

HANOI - A patient has died of bird flu in northern Vietnam, state television announced late Saturday, the first death from avian influenza in the country since November 2005.

The patient, whose age and sex were not given, died nearly a week ago in Ha Tay province, the television said, citing a report by the Vietnamese health ministry.

It brings to 43 the number of people who have died of the human form of bird flu in Vietnam since the virus reappeared in Southeast Asia at the end of 2003. AFP
 

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Suspected case of avian influenza found in Togo

http://news.xinhuanet.com/english/2007-06/16/content_6250021.htm

LOME, June 15 (Xinhua) -- A suspected case of avian influenza was found in the village of Sigbehoue in an eastern province of Togo, which recently experienced a massive death of poultry, Togo's national radio station reported on Friday evening.

The report said blood sample has been sent to laboratory for further test. Togolese authorities called on the public to keep calm, remain cautious, and take measures to quarantine poultry and birds.

On April 24, a case of the H5N1 virus of the bird flu was detected at a poultry farm near Tema, the port city east of the Ghanaian capital, Accra. Togolese authorities have taken a series of measures to prevent and fight against bird flu early May.

The Ministries of Agriculture, Animal Husbandry and Fisheries released a communique on Friday to reiterate its ban on all imports of poultry and poultry products from countries, where the virus has been identified.

The communique said that "in a bid to guard against the scourge, the imports of poultry -live, frozen and day-old chicks from Ghanahave been banned until further notice."

The communique asked civilians, who found sudden and massive deaths of poultry and wild birds, to report it to veterinary departments.
 

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Bird flu-infected man dies in Ha Noi hospital

http://english.vietnamnet.vn/social/2007/06/707269/

11:57' 17/06/2007 (GMT+7)

VietNamNet Bridge - A 20-year old man from Ba Vi district, Ha Tay province, died of the H5N1 strain of influenza type A at the Ha Noi-based National Contagious and Tropical Diseases Hospital on June 10.

The case was reported by Deputy Health Minister Trinh Quan Huan to Prime Minister Nguyen Tan Dung and the National Committee on Bird Flud Control on June 2.

The man was diagnosed of catching the virus on June 2 and moved to the Ha Noi hospital six days later. He became the first Vietnamese to die of the deadly virus after 17 months the country successfully contained the epidemic.

So far this year, five Vietnamese tested positive to H5N1 virus, all from northern provinces. Of them two have been discharged from hospital and the remaining two are under treatment at the National Contagious and Tropical Diseases Hospital.

(Source: VNA)
 

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H5N1 virus detected from bird faeces in HK

http://english.people.com.cn/200706/17/eng20070617_385092.html

H5N1 virus was found in a faecal sample collected from a pet bird shop in the Bird Garden in Mong Kok, Hong Kong Agriculture, Fisheries and Conservation Department (AFCD) said Saturday.

As a precautionary measure, AFCD has temporarily closed the shop in question and removed all its birds, to the Department's animal management center for close observation and further testing, but no other positive cases were detected.

All pet bird stalls in the Bird Garden are being closely monitored for avian influenza among the flocks. So far nothing abnormal has been detected, according to the department.

In response to the incident, AFCD has required all pet bird shop operators in the Bird Garden to undertake a thorough cleansing of their stalls. In addition, AFCD staff would inspect all the stalls and collect swab samples on a daily basis.

Source: Xinhua
 

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Hong Kong Closes Bird Market After Finding Avian Flu (Update1)

http://www.bloomberg.com/apps/news?pid=20601087&sid=aV2Grpl4kxBc&refer=home

By Hanny Wan

June 17 (Bloomberg) -- Hong Kong ``temporarily'' closed the city's bird market after finding the H5N1 virus in a starling in a shop there, the government said.

Officials detected the virus in a fecal swab sample taken from a Daurian Starling in the bird market on June 4, the Agriculture, Fisheries & Conservation Department said in a statement released late yesterday.

Yuen Po Street Bird Garden will remain closed while stalls are disinfected, the department said. The market, a popular tourist destination in the city's Mongkok district, is packed with shops selling pet birds, as well cages, live crickets and other accessories.

The department removed all the birds in the shop where the starling was found, and will collect swab samples daily when the market reopens. Stall owners and employees are all under medical surveillance, the statement said. No date was given for the reopening of the market.

Vietnam reported yesterday its first human death from bird flu since November 2005, Agence France-Presse said, citing the nation's state television.

As of June 12, 190 people worldwide have died of avian influenza since December 2003, according to the World Health Organization.
 

kelee877

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Kids are front-line flu spreaders TheStar.com - News - Kids are front-line flu spreaders
Threat of avian flu hot topic for scientists at T.O. conference

June 17, 2007
Tanya Talaga
Health Reporter
Influenza researchers are starting to pay close attention to the role children could play as disease carriers during a dreaded flu pandemic.
Should kids go to school with masks? Should children be vaccinated first to limit spread? Is it worth shutting schools down?
These are hot topics for scientists gathering in Toronto this week at an international conference on fighting the flu, a respiratory illness that kills nearly 500,000 people around the world annually. In a pandemic, millions more could die.
Hanging over the conference, which opens today at the Metro Convention Centre, is the threat of the H5N1 virus or avian flu, which many predict could be responsible for the next pandemic. With isolated incidents of transmission from birds to humans reported around the world, health officials worry it could prove deadly if it mutates and spreads from human to human.
Vaccine production, new antiviral medications and how to hand out treatment in a pandemic will be discussed, said Dr. Allison McGeer, a Mount Sinai Hospital microbiologist who will present her research on hospital-acquired flu.
Most scientists agree pandemic flu will be affected by antiviral drugs to reduce symptoms and control spread. A hurdle will be how to get enough medication out fast.
Kids' role in flu outbreaks is being studied since they can act as an early-warning system, said John Brownstein, an epidemiologist at Boston Children's Hospital whose work showed the elderly end up in the emergency ward 30 days after 3- and 4-year-olds – who "tend to be the front-line age group" – become sick.
Preschoolers can signal what's to come, he said. They don't practise perfect hygiene, like covering coughs or washing their hands, so they're efficient viral spreaders.
Research continues on the benefits of schoolchildren wearing masks, and whether a kids' nasal flu vaccine stops seasonal outbreaks.
"One of the few things we can all agree on about the pandemic is if children are at risk, the whole focus is kids," said McGeer.

http://www.thestar.com/printArticle/226293




This is from the Toronto star newspaper...I had to post...very rarely do we get news about avian flu in any of our papers or on our news channels...edited to say; I am in Canada
 

JPD

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Vietnam flu case a warning: experts

http://www.gulf-times.com/site/topi...=155774&version=1&template_id=45&parent_id=25

Published: Monday, 18 June, 2007, 10:15 AM Doha Time
HANOI: Vietnam’s first human death from bird flu in more than a year has highlighted growing complacency among farmers in fighting the virus that remains endemic in the country, experts said yesterday.

A 20-year-old man from a province neighbouring the capital Hanoi was killed by the H5N1 strain a week ago, the communist government said, and four more people are known to have been infected with the virus since last month.
The country’s first bird flu death since October 2005 comes as avian influenza has made a strong resurgence across Vietnam, hitting poultry flocks in over 100 outbreaks across 18 of the country’s 64 provinces and municipalities.

“This is not going to go away,” said WHO’s Vietnam communications officer Dida Connor, speaking before news of the human death. “There is a sense of complacency which is potentially catastrophic if it was to increase.”

The human fatality, which brought the country’s bird flu death toll to 43, followed several avian influenza cases across Southeast Asia last week.

On Thursday, Indonesia said a 29-year-old man had died of bird flu, bringing the death toll in the country worst hit by the virus to 80.

In Malaysia five people were quarantined with suspected bird flu, while Myanmar reported a fresh poultry outbreak.

Vietnam’s unusual summertime outbreak, concentrated in the densely populated northern Red River delta region, follows the ending in March of a two-year ban on duck hatching that has triggered a surge in production.

Nationwide vaccination campaigns — widely hailed as a model that other countries have sought to emulate — have become increasingly spotty, Vietnamese and international animal health officials have warned.
“We’ve had bird flu for four years,” said the UN Food and Agriculture Organisation’s Vietnam bird flu specialist Jeffrey Gilbert. “Everyone’s tired of it... but it’s going on, and we are increasingly challenged to get these messages across to people that the risk hasn’t gone away.”

“People get very bored very quickly,” he added.

“We can get the farmer to come in once or twice, but the third time he may see that it’s not much of a priority anymore. He may not bother, or he may bring in 50 ducks and not bother to notify the authorities that there’s another 150 (needing vaccination) still in the field.”

Ducks and other waterfowl, which can carry and spread the virus without showing symptoms themselves, have been the major source of infections in the latest wave of outbreaks, Vietnam’s fifth since 2003.

Flocks of ducks roving across rice paddies and ponds are a traditional, iconic feature of the Vietnamese countryside. After the lifting of the ban, they have come back in great numbers following the northern rice harvest.

Prime Minister Nguyen Tan Dung last week ordered the agriculture ministry to map out immediate and long-term action plans to fight bird flu, concentrating on vaccinating Vietnam’s 70mn ducks and culling all sick animals.

Experts warn that H5N1 survives both in the respiratory system and the gastro-intestinal tract of birds — meaning farms, markets and slaughterhouses have to be vigilant about hygiene and biosecurity.

Vietnam, once the country worst affected by H5N1, was hit by three waves of avian influenza in 2004 and 2005, when 42 people were killed and authorities culled more than 50 mn head of poultry.

No new outbreaks were reported for 12 months, until fresh infections last December led authorities to cull 45,000 poultry. Sporadic outbreaks have been reported since February, but cases picked up sharply in May.

Worldwide, bird flu has killed 191 people out of 313 infected patients, says the WHO, which has not yet confirmed Vietnam’s latest human cases.

Experts fear the death toll would rise sharply if the virus were to mutate and become easily transmitted between humans. A flu pandemic in 1918, just after the end of World War I, killed 20mn people worldwide.–AFP
 

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Bird flu spreads in Bangladesh, more fowls culled

http://africa.reuters.com/commodities/news/usnDHA102207.html

Mon 18 Jun 2007, 5:32 GMT

DHAKA, June 18 (Reuters) - Bird flu has spread to another district in Bangladesh, forcing authorities to cull 7,000 chickens, officials said on Monday.

The infected chickens were buried after the H5N1 strain of bird flu was detected on two farms in Jaipurhat district, 300 km (188 miles) northwest of the capital, Dhaka.

With the latest cull, about 172,000 chickens have now been slaughtered and more than 1.6 million eggs destroyed on 68 farms in 14 districts since the virus was first detected near Dhaka in March.

There have been no reported cases of human infection.

More than 110,000 farms have been inspected and 133 million chickens vaccinated since the outbreak emerged, a fisheries and livestock ministry statement said.

Bangladesh has more than 125,000 poultry firms producing 250 million broilers and six billion eggs annually.

About four million Bangladeshis are directly or indirectly associated with poultry farming.
 

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Race to find owner of H5N1 bird

http://www.thestandard.com.hk/news_detail.asp?pp_cat=11&art_id=47091&sid=14106846&con_type=1

Carol Chung and Emily Wu

Monday, June 18, 2007

Officials of the Agriculture, Fisheries and Conservation Department are trying to track down the owner of a bird after H5N1 virus was found in its droppings.

The bird - a Daurian starling - was left at a Mong Kok pet shop on Yuen Po Street, commonly known as "Bird Street," two week ago, but it is not known whether it was intended for sale.

Infectious diseases expert Lo Wing- lok said it is "very important" the owner of the bird, which is migratory by nature, be located.

"He or she may already have been infected, and the situation could get worse if medical treatment is delayed. People in contact with the person are also at risk. Tracking down this person holds the key to finding the source of the virus," Lo said.

Chung Ho-fai, chairman of the Hong Kong Bird Watching Society, said the sale of wild birds must be banned following the recent spate of avian flu cases detected among such birds in Hong Kong.

Bird flu is blamed for the deaths of 157 people worldwide since 2003. Most victims had direct contact with poultry. Scientists have repeatedly warned of a global pandemic, resulting in the deaths of millions of people, if the deadly avian virus mutates, making transmission possible between humans.

The virus jumped to infect humans in Hong Kong in 1997, killing six of the 18 people infected and prompting the authorities to cull more than two million fowl.

The latest H5N1 scare at a shop called Indonesia resulted in an order for all pet shops on Yuen Po Street to close.

About 300 birds from the affected shop have been taken to the AFCD's animal management center in Sheung Shui for tests and observation. The fecal sample taken from the Daurian starling June 4 was part of the department's routine bird-flu surveillance program.

The Leisure and Cultural Services Department is cleaning stalls on the street.

The Centre for Health Protection under the Department of Health has set up a hotline - 2125 1122 - for the public. The center is closely monitoring the health of stall operators as well as workers.

A woman surnamed Law, who has been selling grasshoppers - a bird food - on the street, said the order to close has driven her out of business.

"We're not allowed to go inside. The gate has been locked. Usually, I can earn about HK$1,000 to HK$2,000 a day. There's hardly any business today [Sunday]," Law said.

She said it was not a matter of being scared of H5N1 but she had to make a living. "I always wear a pair of gloves and wash my hands. I believe it can help lower the chance of getting infected," Law said.

Another bird-food vendor surnamed Cheng said her business has also been badly hit. "I have been busy cleaning my stall. I just wonder how long our stalls will have to remain closed."

Another vendor said she used to sell bird food to her regular customers. "I earn a few hundred dollars a day. That helps a bit or else I can't imagine how I can sustain my living."

Visitors to "Bird Street" were also disappointed by the closure. The Wong family who traveled to Mong Kok from Chai Wan, hoping to buy an oriole as a Father's Day present, said there should not be any cause for alarm.

"I believe the government can handle the matter well. I'm not worried about the spread of the H5N1 virus in Hong Kong," Mrs Wong said.

However, others said they were quite concerned about the possible spread of the virus in the territory.

A woman, who was shopping with her boyfriend at the flower market opposite the pet shops, said: " I came today trying to get a Father's Day present. I will try to avoid going near Bird Street."
 

JPD

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Veterinarians Could Be First to Get Bird Flu

http://news.yahoo.com/s/hsn/20070618/hl_hsn/veterinarianscouldbefirsttogetbirdflu

MONDAY, June 18 (HealthDay News) -- Because veterinarians who work with birds are at increased risk of infection with bird flu viruses, they should be included on lists of people with priority access to pandemic flu vaccines and antiviral drugs, U.S. researchers say.

A team at the University of Iowa College of Public Health analyzed blood samples from a group of American veterinarians who worked with chickens, ducks, turkeys, geese or quail.

They found that their blood had increased levels of antibodies against the H5, H6 and H7 avian influenza viruses. These increased levels indicated that the veterinarians had previously been infected by these viruses.

These mild forms of bird flu occasionally circulate among wild and domestic birds in the United States. But experts fear that the deadly H5N1 bird flu virus that emerged in Asia may mutate into a form that's easily transmitted between humans and trigger a global pandemic.

"Veterinarians and others with frequent and close contact to infected birds may be among the first to be infected with a pandemic strain of influenza," study author Kendall Myers, a doctoral student in occupational and environmental health, said in a prepared statement.

"They have the potential to spread the illness to their families and communities. Because of this, we suggest that veterinarians should be considered for inclusion on priority access lists for pandemic influenza vaccines and antivirals," Myers said.

The study is published in the July 1 issue of the journal Clinical Infectious Diseases.
 

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Health department sends outs pandemic flu preparedness handbooks

http://www.dailycomet.com/article/20070618/APN/706180632

BATON ROUGE, La. The state health department sent out 1.6 million pandemic flu preparedness handbooks Monday, to tell citizens how to guard against the virus.

"This is a very real threat," Dr. Jimmy Guidry, state health officer, said in a statement. "It's not a matter of 'if' a pandemic flu will strike, but a matter of 'when.' That's why we're arming the public now with the knowledge of how to prepare and protect themselves against a pandemic event that could quickly sweep the world."

The handbooks from the Louisiana Department of Health and Hospitals should being arriving in mailboxes around Louisiana this week, with information about vaccines and antiviral medications, travel precautions, preparations already under way and general information about pandemic flu.

The handbook distribution is another in a series of events to prepare for pandemic flu. The state oversaw a pandemic flu summit, developed a pandemic flu plan and held regional exercises and a statewide drill to prepare, DHH officials said. Later this month, New Orleans will host a National Governors Association workshop on pandemic flu preparations.
 

JPD

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Allocation of antivirals for flu pandemic workers stirs debate

http://www.cbc.ca/health/story/2007/06/18/flu-antivirals.html

Public health officials across Canada are grappling with the medical and ethical issues of giving front-line health-care workers preventive antiviral drugs if a flu pandemic strikes.

The federal and provincial governments have stockpiled more than 500 million doses of antiviral drugs to prepare for a pandemic.

'We have to be there to look after the ill population, and if we're not there because we're sick, people are going to die.'— Infectious disease expert Dr. Michael Gardam argues antivirals should be stockpiled for health-care workers as a preventive measure against a flu pandemic

Under the current federal plan, the drugs may only be used to treat people once they are ill, a reversal of an original decision two years ago to stockpile antivirals as a preventive treatment or prophylaxis for front-line health-care workers as well.

Antiviral drugs such as Tamiflu offer the best hope of protecting health-care workers in the event of a pandemic and keeping them on the job to treat patients, said Dr. Michael Gardam, an infectious disease expert at Toronto's University Health Network.

Following the outbreak of SARS in 2003 that killed 44 people in Toronto, most large hospitals in Ontario decided not to take chances and have stockpiled Tamiflu for their employees.

If there is a shortage of Tamiflu, Gardam said, hospitals have been told the Ontario government has the right to confiscate the drugs bought for preventive purposes, but he disagrees with that approach.

"It's a bit like we're going to say we're going to war, but not provide our soldiers with the right stuff necessary to actually make them safe in that setting," Gardam said.

"We have to be there to look after the ill population, and if we're not there because we're sick, people are going to die."
As jury remains out, countries vary approaches

But the antiviral drugs may not work against a new and deadly flu virus, and the preventive treatment could build up resistance to the drug, said Dr. Eric Young, head of pandemic planning in British Columbia.

"We're looking at hundreds of millions of dollars in potential costs, and those are hundreds of millions that will basically be kept out of the health-care system for other things such as MRIs, dialysis, hiring of other health-care workers," Young said.

The scientific jury is out on the practice, agreed Dr. Arlene King, head of pandemic planning at the Public Health Agency of Canada, saying there are no "instantaneous answers" to the issues.

Australia and European countries have set aside some of their antiviral stockpiles for preventive treatment.

The U.S. and United Kingdom are taking a different approach by buying vaccine for the H5N1 bird flu virus, betting that the strain will cause the next pandemic.

After holding public hearings on the value of using antivirals for preventive purposes, public health experts in Canada are reviewing the federal antiviral decision. Their recommendations won't be made public for months, but it could lead to the policy changing once again for the federal and provincial governments.
 

JPD

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Wild ducks carrying bird flu virus registered in Siberia

http://www.itar-tass.com/eng/level2.html?NewsID=11639714&PageNum=0

NOVOSIBIRSK, June 19 (Itar-Tass) - Wild ducks that had been infected with bird flu, but recovered from it were registered in the Altai territory, the Tomsk region, Buryatia and the Ust-Ordyn Buryat autonomous district, a regional department of the Russian agriculture watchdog told Itar-Tass on Tuesday.

“These birds either had contact with infected birds or carried the virus themselves to recover,” the source said. “Forty-seven probes exposed genetic material of the virus and presence of antibodies in blood serum.”

Measures are being taken throughout Siberia to prevent bird flu outbreak.

“As of June 19, no bird flu cases of poultry have been registered so far,” the source said.

Around 6 million poultry are located in high-risk zones of the Siberian federal district. Around 4.4 million of them have already been vaccinated.
 

JPD

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Bird flu clusters on the increase

http://www.scmp.com/portal/site/SCM...0VgnVCM100000360a0a0aRCRD&ss=Hong+Kong&s=News

(Subscription)

Mary Ann Benitez
Jun 18, 2007

The World Health Organisation is investigating clusters of bird flu cases which have been occurring increasingly since late 2005, a visiting WHO official said.

Forty-two clusters involving 111 people have been identified, with a mortality rate of 65 per cent. Ten out of 12 countries with human cases of bird flu have had at least one cluster.

The WHO concluded that limited human-to-human transmission could not be ruled out in 20 per cent of the clusters.

"We have to rule out human transmission. For that reason, clustering is very important for us in terms of catching a possible pandemic at the early stage," said Nikki Shindo, medical officer with the WHO's global influenza programme in Geneva.

She said sporadic cases of bird flu were expected, given that there were ongoing poultry outbreaks. So far, those clusters investigated have not progressed beyond the third generation of victims.

Takeshi Kasai, regional adviser in communicable diseases surveillance and response at the WHO western Pacific regional headquarters, said the latest assessment was that the risk for a pandemic remained the same as it had been since 2003.

The WHO officials were interviewed on the fringes of a closed-door workshop on outbreak communications, which ended on Friday.

The WHO has tried to determine why clusters of cases occurred.

"There are several hypotheses. One of them is that the infected family member has a genetic characteristic to get the disease more easily than the others. The other hypothesis is perhaps they had a heavier exposure than anybody else," Dr Shindo said.

There could also be some environmental factors at play, she said.

Ninety-two per cent of the cases involved blood relatives and 89 per cent were aged under 40. The index cases involved contact with sick or dying poultry. Many clusters had seen parent-to-child or sibling-to-sibling infections, but spouses infecting each other had not been seen.

Clusters involve two or more people who are epidemiologically linked. The largest cluster found, involving eight people, was in North Sumatra in May last year.
 

JPD

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Are we missing the forest in the bird flu fight?

http://www.thejakartapost.com/detaileditorial.asp?fileid=20070619.F05&irec=4

Emmy Fitri, Jakarta

The bird flu outbreak here seems to have died down, with only four fatalities recorded in the past three weeks. That is, of course, good news for people.

But the health authorities and the National Committee for Avian Influenza Control and Pandemic Influenza Preparedness don't appear to see it that way. They are still blaming the public for being ignorant of the deadly virus.

"There are still people who haven't fully understood how important it is to protect themselves from the virus. We still need to promote these life-saving messages, over and over again," the committee's executive chairman Bayu Krisnamurthi said recently.

He acknowledged the infection rate had declined in the last year, but noted the fatality rate had risen to over 79 percent.

New cases of human infection have been found in rural areas, making it difficult for medical aid to arrive quickly. Most of the 44 bird flu referral hospitals across the country are located in cities.

What does it all mean?

The public's inability to put into practice bird flu preventive measures and all the information they have received about the highly pathogenic virus may also demonstrate the authority's tendency to look at the tree but fail to see the forest.

Making up the tree are people, who lack knowledge, live in close proximity with chickens and, perhaps, resist advice.

When the public is blamed for the belated detection of a bird flu case, doesn't some of the fault also belong to the health services which are perhaps unprepared and inaccessible to people?

The public neither has the access to check the stockpile of the wonder drug oseltamivir, nor time to do so, but they may want to know where the pills are available in non-referral hospitals.

Are hospitals, regardless of their classes, and doctors, regardless of their specialties, on alert for bird flu cases? Only the health authorities know the answer.

What must the public know about bird flu, anyway?

Do they have to know all the scientific updates (if there are any), no matter how terrifying they are? Or do they only need to have fragments of the most easily comprehended parts of the updates?

The fact that the virus -- H5N1 -- is so lethal it can jump over to humans is just one thing that is readily understood. That this was originally a poultry disease and should not be out of the chicken coops is still hard to understand.

The average person may not need a detailed explanation as to why the virus can jump into the human body or how the microbe ravages human lungs. What they really need to be convinced of, again and again, is that they really can get sick if they touch sick birds and don't wash their hands afterward.

Most news about bird flu in the media is only when someone has died or is critically ill because of the virus. Then there is an inevitable growing understanding that this is a battle between the public and the virus.

Worldwide, Indonesia has the highest number of human fatalities from bird flu with 80, and millions of chickens, most raised by backyard farmers, have been culled since 2005.

For a change, the public got a different kind of news when the Health Ministry decided to cease sharing bird flu strain samples in March. But the benefit to the public was absolutely nothing; not even an assurance that their lives would be saved in case of a bird flu pandemic.

The authorities have failed to make the dangers of bird flu to humans clear. So why should people be overly concerned about defending themselves against a danger which they think is absent?

A human vaccine is undeniably a good idea and no less noble than developing a poultry vaccine. The problem with a vaccine for humans is that not all 210 million people will get it because of the technicalities of making vaccines and their shelf-life.

Another problem with human vaccine production is that it is costly and time consuming.

The effort to produce a human vaccine is another tree that is overlooked. The tree doesn't stand long before it is brought abroad, in the international context, not for the interests of the public.

Another tree that officials have missed is the poultry sector. Very few in the public hear from this sector, other than losses and outbreaks. What has been done so far remains in the dark, as mystery shrouds the virus.

Therefore, can the public be blamed?

The public represents an uncountable mass. On paper it always seems pardonable to put the blame on the public. Why not, rather than having nothing to report at all?

But in reality, it is extremely hard to blame the public, and what exactly have they done wrong that they deserve the blame.

Both the trees and the forest are green. The tree is too easy to spot, while the forest is too wide to see: better health services, responsive health workers and a better environment in which to live.
 

JPD

Inactive
Analysis: Bird flu fears reignited

http://www.upi.com/Health_Business/Analysis/2007/06/19/analysis_bird_flu_fears_reignited/5905/

Published: June 19, 2007 at 2:34 PM

By ED SUSMAN
TORONTO, June 19 (UPI) -- While the threat of a bird flu pandemic continues to hang over the world, authorities in the United Kingdom now believe a second strain of avian flu -- previously considered of little human risk -- does indeed pose a real danger to people.

"When you have to hospitalize someone for respiratory illness in the U.K., where hospital beds are hard to allocate, then the person has a serious illness," said Jonathan Nguyen-Van-Tam, a senior lecturer at Public Health Laboratory Services in London.

"In this outbreak, we had four people who tested positive for H7 influenza strain, and three of them were hospitalized," he told United Press International. "One person was a candidate for intensive care before he finally came around.

"I think we need to reconsider the H7 strain on the basis of this outbreak," Nguyen-Van-Tam said in reporting how British authorities dealt with the disease encountered on small farms in Wales in the spring of this year.

He presented the report in a special late-breaker session at the Options for the Control of Influenza VI conference in Toronto, attended by more than 1,400 healthcare professionals.

Worldwide, the H5N1 strain of avian influenza, the so-called bird flu, has infected 313 humans and killed 191 of them. The H5N1 disease, seen sporadically since 1996 in Southeast Asia, Europe and Africa, does infect human beings with a strain that is not easy to combat, but so far, its ability to effectively spread from human to human has not occurred. However, health authorities worldwide are nervously watching for that possibility.

But while experts prepare for that grim possibility, a lesser-known relative of the H5N1 virus may be emerging as an equally formidable threat, based on what health authorities encountered recently on a handful of tiny chicken farms in Wales and northern England.

Authorities were alerted to an outbreak there at a smallholding -- a small farm often considered to be inefficient for profitable farming -- where 30 to 40 hens were kept. The farmer had purchased 10 new hens from a trader at the Chelford Market in England.

When the new hens began dying between May 1 and May 17, health authorities from both countries descended on the farm, testing the sick birds and determining that the birds had H7N2 disease.

Health officials also found illness in the farmer's wife and the farmer, a neighbor/visitor and her partner. Only the neighbor's partner tested positive for H7. The partner was not hospitalized but was treated with oseltamivir, sold as Roche's Tamiflu.

Tracking sales at the live poultry market through primitive sales records, Nguyen-Van-Tam said the health agency was led to another smallholding -- so small that the birds were being raised inside the home.

Ducklings purchased around May 7 began getting ill and dying on May 10. By May 15, the pregnant resident and a male resident were hospitalized with influenza-like illnesses and both later tested positive for H7 disease.

With two such cases on record, authorities tried to find the dealer who sold the sick animals but had problems finding him on his farm on the Llyn Peninsula in Wales. That was because, Nguyen-Van-Tam said, the farmer had been hospitalized for five days with an influenza-like illness. He also tested positive for H7 disease.

Authorities then discovered another outbreak among hens purchased at Chelford May 7 at another smallholding in St. Helens in northwest England. The surviving birds tested positive for H7. However, the resident who had an influenza-like illness and his 3-year-old grandson who developed a fever both tested negative for H7.

Over the course of the investigation, people who had contacts with the birds or with the patients were treated with oseltamivir. Eventually that amounted to 369 individuals, 31 of whom had contacts with the birds.

Nguyen-Van-Tam said 23 people developed some form of influenza-like symptoms during the course of the investigation and cleanup. Fourteen of those individuals had secondary contact, but none showed immediate exposure to H7 virus.

Blood testing to further determine if there was spread of the disease is under way. Nguyen-Van-Tam said the investigation was even more difficult because the outbreaks occurred during the seasonal influenza outbreak, making it difficult to determine with sophisticated testing if the patients were infected by the seasonal bug or by avian flu.

"This was a challenging incident," Nguyen-Van-Tam said, "complicated in terms of time and space. No evidence of person-to-person transmission has been found, but serology tests are awaited."

Nguyen-Van-Tam also reported on efforts to contain an H5N1 outbreak in February on a turkey farm in Suffolk, England.

That outbreak was contained in three days, during which authorities slaughtered 160,000 turkeys and treated 482 people who worked on the large poultry farm or were from public health offices engaged in capturing the turkeys and euthanizing them.

The people exposed to the birds were treated with oseltamivir, but no human cases of H5N1 occurred in that incident.
 

JPD

Inactive
Bird flu virus on the move, conference told

http://www.thestar.com/article/226960

Jun 19, 2007 09:00 AM
Tanya Talaga
Health Reporter

Some African nations are experiencing a rapid spread of the H5N1 virus in poultry while a lack of equipped public health labs, customs surrounding chickens and poor surveillance hamper pandemic plans, a conference on the flu heard yesterday in Toronto.

In just over a year, Avian flu or the H5N1 virus, arrived in Africa and spread to nine countries, three of which now have human cases, said Dr. Stella Chungong, a medical officer with the World Health Organization Influenza Programme.

In Nigeria, the H5N1 virus first infected poultry about a year ago and has now spread to 22 out of 36 states.

There has been one human death from H5N1 in Lagos, the largest city in Nigeria. In all of Africa, it’s believed 38 people have become sick with the virus in the last year, according to Chungong, but it’s unclear whether that’s an accurate number because surveillance is poor.

“We really cannot be sure. That is what the system has been able to pick up. When you have a case, you actively go out and try and find other cases,” she said during the Options for the Control of Influenza VI Conference in Toronto, an international gathering of 1,500 scientists dedicated solely to the flu and hosted by the U.S. Centers for Disease Control and Prevention. The meeting happens every three years.

So far, the H5N1 virus has not been able to spread from human to human. People who catch it get it from infected poultry.

In some African communities, people live in close contact with poultry. Chickens sometimes live in the yard and people often buy birds at unregulated markets to bring home to slaughter and cook. “The public aren’t really aware of the risks,” she said, adding some governments are starting to take notice and get strategic, but not operational, plans in place.

Every yea,r seasonal flu kills 500,000 people. A flu pandemic refers to a particularly virulent strain of influenza that moves rapidly throughout the world, killing and sickening millions. The last pandemic was the Hong Kong flu in 1968, which killed 700,000. Scientists believe the next one could be caused by the H5N1 virus if it mutates and starts to pass from human to human.

While developing nations are struggling to cope with influenza pandemic planning, Canada has already stockpiled enough medication to treat about 5.5 million people with antivirals, which can reduce flu symptoms and contain its spread. “We are focusing on early treatments,” said Dr. Theresa Tam of the Public Health Agency of Canada.

“Our assumptions are about 35 per cent of the population will become sick enough that they’ll seek medical attention, of which 50 per cent will seek intervention early enough that antivirals will be effective.”

The medication does have a shelf life of five years or less, but as time goes on, with continuing testing of the potency, that might be extended, Tam said.

“Looking at the two perspectives, Africa versus Canada, we have to realize how fortunate we are to have the type of public health system and support we’re getting to do our pandemic preparedness,” she said, adding that the SARS crisis in 2003 was a stimulus to put a plan together.

Canada also has the ability to domestically produce a vaccine. Clinical trials are slated to begin at some point this year on the GlaxoSmithKilne H5N1 vaccine.

The conference continues this week.
 

JPD

Inactive
OPTIONS VI: No Evidence For Mild Avian Flu

http://www.medpagetoday.com/InfectiousDisease/URItheFlu/tb/5964

TORONTO, June 18 -- Highly pathogenic avian flu is rarely transmitted to people and apparently never in a mild or asymptomatic form, a Thai researcher said here.
Action Points

* Explain to interested patients that the highly pathogenic H5N21 avian flu has killed more than half the people it infects, but the absolute numbers are very small.

* Note that this study suggests the deaths are not the tip of an iceberg of more widespread but milder disease, as some investigators had thought.

* This study was published as an abstract and presented orally at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed publication.

A study of 901 people who lived near confirmed victims of the H5N1 avian flu strain showed no serological evidence that they had been infected and fought off the disease, Rapeepan Dejpichai, M.D., of the Thai Ministry of Health told attendees at the Options for Influenza Control meeting.

Even those who were in close contact with both infected birds and infected people showed no sign of ever having been infected, Dr. Dejpichai and colleagues found.

The study is consistent with findings in Hong Kong, China, and Cambodia, which showed viral seroprevalence of no more than 10% among poultry workers and people living in villages where H5N1 outbreaks occurred, she said.

But it contradicts a population-based study in Vietnam, published last year, that concluded that mild cases of the virus were likely to be common. (see Mild Avian Flu Transmission May Be Common)

From 2004 through 2006, Thailand had 25 confirmed cases of avian flu in humans, and 17 deaths. Dr. Dejpichai and colleagues interviewed 901 residents of four Thai villages where there had been at least one confirmed human case of H5N1 and an outbreak among poultry.

The participants were mostly male, with a median age of 40; 85.5% were selected by convenience sampling, the rest by random sampling.

Study participants were asked about respiratory illnesses and risk factors, such as exposure to infected birds or the human patients.

The researchers also took blood samples, which were tested for antibodies to the H5N1 virus, using the so-called microneutralization assay and confirmed by ELISA. An antibody titer of greater than 1:40 was considered positive.

The researchers found:

* There were no significant differences between the random and convenience samples.
* 68.1% reported contact with backyard poultry.
* 33.3% reported contact with sick or dead chickens without use of any protective equipment.
* 7.1% reported contact with the infected humans.
* All participants tested negative for H5N1 neutralizing antibodies.

During the time that the human victims were developing the disease, 118 study participants recalled having their own acute respiratory symptoms, Dr. Dejpichai said. Of those, 33% had had contact with sick birds but all had antibody titers less than 1:40 and were considered seronegative for H5N1 infection.

The results suggest that "H5N1 viruses circulating in Thailand during 2004-05 were transmitted inefficiently to humans," Dr. Dejpichai said.

She noted that the study is limited by the large convenience sample, and added that, although microneutralization is the gold standard for flu detection, it is possible that some cases were not detected.

The evidence, including Dr. Dejchipai's study, is mounting that mild or asymptomatic cases of H5N1 don't exist, said Joseph Bresee, M.D., of the CDC, who moderated the session and was not involved in the research.

Some investigators had "the suspicion that the high case fatality rate was because we were missing part of the pyramid," he said. "There were asymptomatic or mild cases that weren't presenting to care, for various reasons."

"More and more people are comfortable with the idea," he said, "that that simply isn't true - that the pyramid is an obelisk or something like that."

The finding is very important for surveillance, he said, because it means public health authorities can focus on places where very sick people are likely to come for treatment - hospitals and clinics.
 

JPD

Inactive
Bird flu hits Aflao

http://www.myjoyonline.com/news/200706/5850.asp

About 1100 birds have been destroyed following the discovery of another case of the Bird flu disease at the border town of Aflao near Lome.

Officials of the Veterinary Service Department detected the virus after a poultry farmer in a community at Aflao took his sick birds to the Veterinary laboratory here in Accra to be tested. The birds reportedly started dying since last Wednesday but did not show any signs of the disease.

The Volta Regional Director of the Veterinary Services, Dr Ben Aniwa told Joy News measures have been put in place in Aflao to prevent the disease from spreading to other parts of the region.

He assured: “We have started the control measures. We have destroyed about 1100 birds and all other birds around the area. Our people are on high alert to make sure that the disease is put under control at the shortest possible time.”

The Volta region becomes the third region to be hit by the disease after it was discovered in Tema of the Greater Accra region and Sunyani in the Brong Ahafo region.
 

Jim in MO

Inactive
Analysis: Bird flu fears reignited

http://www.upi.com/Health_Business/Analysis/2007/06/19/analysis_bird_flu_fears_reignited/5905/

Published: June 19, 2007 at 2:34 PM

By ED SUSMAN
TORONTO, June 19 (UPI) -- While the threat of a bird flu pandemic continues to hang over the world, authorities in the United Kingdom now believe a second strain of avian flu -- previously considered of little human risk -- does indeed pose a real danger to people.

"When you have to hospitalize someone for respiratory illness in the U.K., where hospital beds are hard to allocate, then the person has a serious illness," said Jonathan Nguyen-Van-Tam, a senior lecturer at Public Health Laboratory Services in London.

"In this outbreak, we had four people who tested positive for H7 influenza strain, and three of them were hospitalized," he told United Press International. "One person was a candidate for intensive care before he finally came around.

"I think we need to reconsider the H7 strain on the basis of this outbreak," Nguyen-Van-Tam said in reporting how British authorities dealt with the disease encountered on small farms in Wales in the spring of this year.

He presented the report in a special late-breaker session at the Options for the Control of Influenza VI conference in Toronto, attended by more than 1,400 healthcare professionals.

Worldwide, the H5N1 strain of avian influenza, the so-called bird flu, has infected 313 humans and killed 191 of them. The H5N1 disease, seen sporadically since 1996 in Southeast Asia, Europe and Africa, does infect human beings with a strain that is not easy to combat, but so far, its ability to effectively spread from human to human has not occurred. However, health authorities worldwide are nervously watching for that possibility.

But while experts prepare for that grim possibility, a lesser-known relative of the H5N1 virus may be emerging as an equally formidable threat, based on what health authorities encountered recently on a handful of tiny chicken farms in Wales and northern England.

Authorities were alerted to an outbreak there at a smallholding -- a small farm often considered to be inefficient for profitable farming -- where 30 to 40 hens were kept. The farmer had purchased 10 new hens from a trader at the Chelford Market in England.

When the new hens began dying between May 1 and May 17, health authorities from both countries descended on the farm, testing the sick birds and determining that the birds had H7N2 disease.

Health officials also found illness in the farmer's wife and the farmer, a neighbor/visitor and her partner. Only the neighbor's partner tested positive for H7. The partner was not hospitalized but was treated with oseltamivir, sold as Roche's Tamiflu.

Tracking sales at the live poultry market through primitive sales records, Nguyen-Van-Tam said the health agency was led to another smallholding -- so small that the birds were being raised inside the home.

Ducklings purchased around May 7 began getting ill and dying on May 10. By May 15, the pregnant resident and a male resident were hospitalized with influenza-like illnesses and both later tested positive for H7 disease.

With two such cases on record, authorities tried to find the dealer who sold the sick animals but had problems finding him on his farm on the Llyn Peninsula in Wales. That was because, Nguyen-Van-Tam said, the farmer had been hospitalized for five days with an influenza-like illness. He also tested positive for H7 disease.

Authorities then discovered another outbreak among hens purchased at Chelford May 7 at another smallholding in St. Helens in northwest England. The surviving birds tested positive for H7. However, the resident who had an influenza-like illness and his 3-year-old grandson who developed a fever both tested negative for H7.

Over the course of the investigation, people who had contacts with the birds or with the patients were treated with oseltamivir. Eventually that amounted to 369 individuals, 31 of whom had contacts with the birds.

Nguyen-Van-Tam said 23 people developed some form of influenza-like symptoms during the course of the investigation and cleanup. Fourteen of those individuals had secondary contact, but none showed immediate exposure to H7 virus.

Blood testing to further determine if there was spread of the disease is under way. Nguyen-Van-Tam said the investigation was even more difficult because the outbreaks occurred during the seasonal influenza outbreak, making it difficult to determine with sophisticated testing if the patients were infected by the seasonal bug or by avian flu.

"This was a challenging incident," Nguyen-Van-Tam said, "complicated in terms of time and space. No evidence of person-to-person transmission has been found, but serology tests are awaited."

Nguyen-Van-Tam also reported on efforts to contain an H5N1 outbreak in February on a turkey farm in Suffolk, England.

That outbreak was contained in three days, during which authorities slaughtered 160,000 turkeys and treated 482 people who worked on the large poultry farm or were from public health offices engaged in capturing the turkeys and euthanizing them.

The people exposed to the birds were treated with oseltamivir, but no human cases of H5N1 occurred in that incident.


:shkr: This one gives me the heebies jeebies...

Thanks JPD for your hard work keeping us updated.
 

JPD

Inactive
New HHS contracts to prepare for a flu pandemic

http://www.news-medical.net/?id=26608

HHS Secretary Mike Leavitt has announced the award of two contracts to expand the domestic influenza vaccine manufacturing capacity that could be used in the event of a potential influenza pandemic.

The department has awarded two cost-reimbursable contracts totaling $132.5 million to sanofi pasteur and MedImmune over five years to retrofit existing domestic vaccine manufacturing facilities on a cost-sharing basis and to provide warm-base operations for manufacturing pandemic influenza vaccines. In warm-base operations, the contractor does not shut down the facility.

"We must prepare for a flu pandemic, although it may not be possible to be certain when the next one will come or how severe it will be," Secretary Leavitt said. "These contracts are important advances in the path of preparation because they help the nation build its capacity to respond."

The five-year contracts were awarded to sanofi pasteur, a manufacturer of a U.S.-licensed egg-based inactivated influenza vaccine product, for $77.4 million and to MedImmune, a manufacturer of a U.S.-licensed egg-based live, attenuated vaccine product, for $55.1 million. The contracts provide funding for renovation of manufacturing facilities and manufacturing warm-base operations for two years with options for an additional three years of warm-base operation.

Upon completion, these facilities will expand domestic pandemic vaccine manufacturing capacity by 16 percent. Additionally, these facilities will afford year-round production of pre-pandemic influenza vaccines for the national stockpile, which is limited currently to three months each year.

The HHS Pandemic Preparedness Plan, issued in November 2005, outlines public health preparedness and response activities for an influenza pandemic. Major vaccine goals include the establishment of pre-pandemic influenza vaccine stockpiles for 20 million persons in the critical workforce and the expansion of domestic pandemic vaccine manufacturing surge capacity for 300 million persons within six months of the onset of an influenza pandemic.

HHS' Office of the Assistant Secretary for Preparedness and Response, which oversees medical countermeasure development and acquisition efforts through its Office of Biomedical Advanced Research and Development Authority (BARDA), formerly the Office of Public Health Emergency Medical Countermeasures, will manage these contracts.
 

JPD

Inactive
New tests on bird flu drug after teenagers' deaths

http://www.guardian.co.uk/birdflu/story/0,,2107018,00.html

Trials will look at whether Tamiflu causes delusions
· No evidence of link with symptoms, Roche insists

Justin McCurry in Tokyo
Wednesday June 20, 2007
The Guardian

The reputation of flu drug Tamiflu suffered a fresh blow yesterday when the Swiss pharmaceutical company Roche and its Japanese partner announced new clinical trials to establish whether there is a possible link between the antiviral and dozens of deaths and injuries among Japanese teenagers.

The new research on Tamiflu, which is being stockpiled as the best available treatment in a bird flu epidemic, was recommended by a Japanese health ministry drug safety panel investigating fears that it may have a link to several teenagers who killed or harmed themselves during episodes of extreme mental disorder. In February a boy and a girl, both 14, fell to their deaths.

The ministry said there was no evidence of a causal link between Tamiflu and the symptoms but ordered doctors not to prescribe it to teenagers, except those suffering extreme flu symptoms. It advised Roche and Chugai Pharmaceutical, which sells the drug in Japan, to begin pre-clinical and human clinical trials to establish whether it could be behind side-effects such as delirium and delusion.

Chugai said that the results of the research, expected by the end of the year, would be used "for the best possible safety measures for the next influenza season".

It said it would conduct human clinical trials using 12-30 volunteers, while Roche would conduct toxicity studies using rats to gauge the drug's effects on the brain. "We are taking the situation seriously and are increasing our efforts to look into whether there is any causality."

This week the health ministry said the number of people found to have behaved abnormally after taking Tamiflu had risen from 128 in April to 211 as of Saturday. More than 1,300 people have exhibited neuropsychiatric symptoms since the drug went on sale in Japan in 2001, of whom 71 have died. Twenty-seven, most in their teens, fell from buildings.

Roche says studies have repeatedly failed to find a link with abnormal behaviour. Tamiflu has been used by 45 million people in 80 countries since it went on the market in 1999. Japan accounts for 70% of its use. About 6 million Japanese took it in the 2004-5 flu season.

Roche said tests had shown children using the drug to treat flu were less likely to show such symptoms than those who were not receiving the treatment. A study conducted by the US food and drug administration in 2005 found no causal link. Some experts agree that severe flu symptoms may have caused the behaviour.
 

JPD

Inactive
Officials plan mass flu response

http://www.casperstartribune.net/ar...s/casper/e8d5d5355165ef77872573000004c83b.txt

By ALLISON RUPP
Star-Tribune staff writer Wednesday, June 20, 2007

Casper will be one of 11 distribution centers called upon to receive and administer supplies during a pandemic flu or other public health emergency.

The state and its counties are in the process of working out how Wyoming will distribute large quantities of medicine and medical supplies from the Strategic National Stockpile to all of the state's residents.

The stockpile is a national repository of antibiotics, chemical antidotes, IVs and other medical and surgical items. It is run by the Centers for Disease Control and Prevention and there are secret stockpile sites throughout the country.

At a meeting in Casper Tuesday morning, public health officials from Natrona County listened as Bryon Hopper, the state's stockpile coordinator, laid out this plan via video conference.

Officials in about 14 other counties also participated in the conference.

"We have some pretty important information that has not gotten out there before," Hopper said to begin the meeting. Then he described in detail each step of the distribution process.

If the Wyoming Department of Health's director, Dr. Brent Sherard, feels the state is in need of supplies, they would be immediately shipped to Wyoming's reception, storage and staging (RSS) facility, which will be somewhere in Cheyenne.

About 51 tons of supplies would arrive in Cheyenne within 12 hours. This can fill eight 18-wheeler trucks or one Boeing 747 aircraft, said Marty Thone, spokesman for the Casper-Natrona County Health Department.

"It's enough for approximately 325,000 people," Thone said.

After the medical supplies arrived in Cheyenne, they would be shipped out to each of the other 10 distribution centers. Wyoming Highway Patrol vehicles would accompany each truck.

Thone talked about what would happen when the supplies reach Casper.

He said the county health department is in the process of setting up an agreement with a Casper facility to act as the distribution center. He said he was unable to disclose this location because details had not been finalized.

According to the draft of Natrona County's stockpile plan, Thone said at least four prepackaged stocks of supplies would leave Casper's distribution center to go to Converse County, Niobrara County, the Wyoming Medical Center and the public health department.

Supplies from the public health department stash would then go to several points of distribution throughout the city where people could receive treatment.

"Within 48 hours of requesting the stockpile, we can vaccinate or give pills to 100 percent of our population," Thone said about Casper's plan.

Scott Howe, public health response coordinator for Converse County, said he has been working on his county's response to a pandemic flu or other emergency for about three years.

"This preparation can be used for any event, such as an earthquake," Howe said. "We have to get (the public) cognizant that a pandemic flu is coming."

Hopper said Casper still needs a little work getting its plan nailed down. He said Thone and others have been working hard, but they need to get it documented.

Thone said he was turning in a draft of Casper's plan after the meeting.

It is important the state and counties get these plans documented to continue to get the federal funding they need make sure everything goes smoothly in an emergency.

"Wyoming has always been really good about working together," Hopper said. "If push came to shove we would get things together.
 

JPD

Inactive
Tens of thousands of poultry die of AI in E. Kalimantan

http://www.antara.co.id/en/arc/2007/6/20/tens-of-thousands-of-poultry-die-of-ai-in-e-kalimantan/

Samarinda (ANTARA News) - At least 43,000 poultry in Samarinda city and Kutai Kartanegara distict have been infected with the bird flu (Avian Influenza) virus since last May, a provincial animal husbandry official said.

"Since the first bird flu case was known in 2005, the two regions have been categorized as bird-flu endemic areas but last May there was a flareup in the situation ," the official said.

Speaking after a meeting to coordinate bird flu response and prevention efforts, he said all the infected poultry in the two regions had died or were culled.

In the Kutai Kartanegara distirct in May, 28,200 poultry were infected and most of them in seven of the district`s 12 sub districts were found dead.

In Samarinda city since Mei 573 infected poultry were culled while 15,000 were found dead, he said.

At the coordination meeting it was decided that the East Kalimantan provincial administration would coordinate efforts to be made by all government agencies in the province to respond to bird flu outbreaks immediately to prevent the disease from spreading to other cities or districts outside Samarinda and Kutai Kartanegara.

Although so far the virus had not affected humans in East Kalimantan, the provincial health office had provided six hospitals in the region with equipment to treat bird flu patients.

Meanwhile, the chairman of the East Kalimantan Association of Poultry Breeders, Sumarsongko, asked local animal health authorities to initiate efforts to familarize poulty breeders in the province with symptoms of bird flu and methods to check poultry`s state of health as many of them still lacked the knowledge or did not employ people who had the capability to detect the disease.

He also said since the recent bird flu outbreaks among poultry, many people had become reluctant to consume chicken meat and as a consequence, the market price of poultry had dropped resulting in lower income for poultry breeders.

Therefore, he said, he hoped the provincial administration would not hurry to declare the bird-flu situation an "extraordinary happening" (KLB) us such a measure would cause poultry breeders to suffer even greater losses.

The market price of a live chicken weighing 1.5 kilograms had dropped to Rp4,000 per chicken and that of a chicken weighing 2 kilograms to Rp6.000 since last May, Sumarsongko said. (*)
 

JPD

Inactive
Czechs discover first bird flu outbreak in poultry

http://in.today.reuters.com/news/ne...R_RTRMDNC_0_India-304034-1.xml&archived=False

PRAGUE (Reuters) - The Czech State Veterinary on Wednesday confirmed the country's first case of bird flu in poultry, the CTK news agency reported.

The agency quoted the veterinary office as saying it would take until Friday to know if the case, found in a turkey, was the deadly H5N1 strain.

A state veterinary office spokesman could not immediately confirm the CTK report.

Health experts fear the bird flu virus could combine with a human form and mutate into a contagious disease for which people have no resistance.
 

JPD

Inactive
Vietnam reports second bird flu death in 10 days - official

http://orange.advfn.com/news_Vietnam-reports-second-bird-flu-death-in-10-days-official_21123876.html

HANOI (XFN-ASIA) - A 28-year-old woman has died of bird flu in Vietnam, the
second person to succumb to the deadly H5N1 strain in just 10 days, after one
and a half years with no deaths, an official said.

She died yesterday two weeks after being admitted to a Hanoi hospital, said
the director of the state-run National Institute of Hygiene and Epidemiology.

Last weekend authorities reported the death of a 20-year-old man, who was
the first fatality to be announced since November 2005. The latest death brings
the country's total deaths from the flu to 44.

Vietnam contained earlier outbreaks through mass vaccination campaigns, the
culling of millions of poultry, and public education campaigns.
But the virus has come back strongly this year. Outbreaks have been reported
since early May across 18 of Vietnam's 64 provinces and municipalities.
afp
 

JPD

Inactive
Possibility of Bird Flu in Taxila escalating

http://paktribune.com/news/index.shtml?181730

TAXILA: Possibility of Bird Flu is on a rise in Taxila after numerous chickens were found dead at various areas.

Sources reveal that possibility of Bird Flu is on rise in Taxila and adjoining areas after supply of sick chickens that later died in the shops.

Further, it has been told that shop keepers are purchasing ailing chickens on decreased rates and later selling them on higher rates thus looting masses with both hands.
 

JPD

Inactive
Bird flu fears in east Bohemia

http://www.praguepost.com/articles/2007/06/20/bird-flu-fears-in-east-bohemia.php

By Hela Balinova
Staff Writer, The Prague Post
June 20th, 2007

Czech veterinary officials have cordoned off a turkey farm in east Bohemia to keep the highly contagious bird flu virus from spreading, after 1,600 turkeys died there.

Laboratory tests show the birds had the most common type of bird flu, according to a statement from the State Veterinary Association. Additional tests are expected.

The flu virus can spread to humans who work with the birds. In other countries with such flu outbreaks, about 60 percent of humans infected with the flu strain have died.

Requests for comment from the European Union office in Prague were not immediately returned. The European Union in the past has banned imports of poultry products deemed potentially risky from counties with bird flu outbreaks, according to information on its Web site.

Bird flu epidemics in Asia in recent years have killed millions of birds and scores of humans. A United Nations office created to address a potential pandemic in 2005 warned that a wider flu outbreak could kill 5 million to 150 million people.
 

JPD

Inactive
U.S. leads bird flu preparation efforts: report

http://news.yahoo.com/s/nm/20070621/hl_nm/birdflu_usa_dc_1;_ylt=A9G_R3qr4npGo7MAHhGTvyIi

WASHINGTON (Reuters) - The United States has pledged more than a quarter of all the funds being used to prepare the world for an influenza pandemic, but is still having trouble identifying which countries need the most help, according to a report released on Thursday.

U.S. agencies have committed about $377 million to improve global preparedness for avian and pandemic influenza, said the report by the Government Accountability Office, the nonpartisan investigative arm of Congress.

"This amounted to about 27 percent of the $1.4 billion committed by all donors combined; exceeded the amounts other individual donors, including the World Bank, the Asian Development Bank, and Japan, had committed; and was also greater than combined commitments by the European Commission and European Union member countries," the GAO report reads.

"The U.S. Agency for International Development and the Department of Health and Human Services have provided most of these funds for a range of efforts, including stockpiles of protective equipment and training foreign health professionals in outbreak response," the report added.

Health experts almost universally agree that the world is overdue for some sort of pandemic of influenza. Flu pandemics hit three times in the past century, killing millions, and it has been 40 years since the last one.

The H5N1 avian flu virus currently circulating among birds in Asia, parts of Europe and Africa is the No. 1 suspect. It is responsible for the death or destruction of an estimated 200 million birds. It rarely affects humans but has infected 313 people and killed 191 since 2003.

A few small mutations could give it the ability to pass easily from one person to another, sparking a pandemic.

Health experts also agree that almost no one is ready for this, and a pandemic would not only kill millions but would devastate economies, disrupt industries from tourism to retail and bring trade to a near standstill for months.

The GAO report said the Homeland Security Council had designated 20 priority countries for U.S. assistance, with the top three being Indonesia, Nigeria, and Egypt.

"USAID ... emphasized that in the coming months the agency will be focusing in particular on developing more effective approaches to controlling the spread of H5N1 in small-scale 'backyard farms' where high-risk agricultural practices are common," the report reads.

Most of the people infected with H5N1 have handled infected poultry, usually from small family flocks.

"Efforts to assemble more comprehensive information are under way, but will take time to produce results," the report added.

It said the U.S. Centers for Disease Control and Prevention was trying to develop a scorecard to systematically assess which countries were ready and where help was needed.
 

JPD

Inactive
How can IT respond to a flu pandemic?

http://www.computerworld.com.sg/ShowPage.aspx?pagetype=2&articleid=5510&pubid=3&tab=Home&issueid=114

By Robert L. Mitchell
Computerworld Singapore

Monday morning, 9 am. The CEO calls you into an executive meeting as word comes that a full-blown H5N1 avian influenza pandemic is spreading rapidly from central Asia. Your job: Keep mission-critical IT systems working despite staff absenteeism rates that could reach 40 per cent at the height of the pandemic, which is expected to run its course over a period of six to eight weeks.

Supply chain disruptions are expected as countries close their borders, so you can’t count on spare parts. With emergency travel restrictions in effect, you can forget about moving staffers between global locations to cope with labor shortages. You also need to enable remote access for an unprecedented number of employees who will either be out sick, caring for ill family members or afraid to come to the office. You have weeks, possibly just days, before the outbreak overtakes one of your major data centers.

Are you ready? For many businesses, the answer is probably no.

LACK OF READINESS A NORM

Like many small- and mid-sized companies, Cleveland-based Kichler Lighting has yet to start business continuity planning. “Pandemic or otherwise, we have no plan or structure, nor the thought process, to address it,” says CIO John Schindler, adding that he’d like to make it a higher priority.

Companies like Kichler are the norm, not the exception, says Stephen Ross, national leader of the business continuity management practice at Deloitte & Touche in New York. “The vast majority of organizations have not done anything,” he says.

Even large companies are playing catch-up.

In a Deloitte survey of 163 large companies conducted last month, 48 per cent of respondents said their companies haven’t adequately prepared for a pandemic. That’s 14 percentage points better than the same survey the previous year. But, Ross adds, “while many large companies have begun their pandemic planning efforts, there’s still a significantly large number that have not.”

Why such inaction? A major pandemic hasn’t occurred in years, and the probability of an outbreak this year can’t be predicted with certainty.

That may lull businesses into a false sense of security, but the potential for catastrophic losses makes planning vital, say pandemic experts and business continuity planners. “The impact of this is so high that the risk rating tells you this must be a priority,” says Don Ainslie, global security officer at Deloitte.
Not if, but when

“The probability of a pandemic outbreak is [100 per cent],” says Michael T. Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota in Minneapolis. It’s just a matter of when, he says.

The World Health Organisation (WHO) has already issued a pandemic alert for the deadly H5N1 virus, although at this point, the virus still isn’t able to spread directly between humans.

“What we need to do,” says Osterholm, “is emphasize to these companies that, unlike many events [such as tornadoes and earthquakes] that may never happen to a company, this is one that will.”

A flu pandemic could devastate companies and the world economy. The US Department of Homeland Security estimates that worker absenteeism could reach 30-40 per cent during a pandemic’s peak. For a corporation with about 20,000 employees, the cost of lost labor and health care could exceed US$60 million, a Deloitte study says.

Supply chain disruptions in one sector, such as the oil and gas industry, could have a domino effect, says Osterholm.

In the worst-case scenario described in a WHO report, if H5N1 mutates directly into a human-to-human transmissible form, the mortality rate could hit 60-65 per cent.

“Obviously, in that kind of worldwide pandemic, it would be as catastrophic as anything we’ve ever seen or known. We’re talking 1 billion or more deaths,” Osterholm says.

UNCERTAIN OR OVERWHELMED?

Martin Meltzer, a senior health economist at the Centers for Disease Control and Prevention in Atlanta, says some sort of pandemic is inevitable, but the uncertainty of when it will occur is affecting the way companies plan.

“What happens if the pandemic doesn’t occur for two years? Will everyone go home and stop planning? That would be a complete disaster,” Meltzer says.

The enormity of the problem may lead some organisations to conclude that there’s little they can do. “There is a real potential to be overwhelmed by the potential intensity of a pandemic and take no action,” says Bill Raisch, director of the InternationalCenter for Enterprise Preparedness at New YorkUniversity.

But organisations need to plan now, says Ainslie. “There’s a lot you can do, and technology is a critical component in this,” he says. And the continuity plans that businesses already have will handle 60-80 per cent of the pandemic challenge, Raisch says.

IN THE HANDS OF TECHNOLOGY

Although planning needs to take place at the executive level, IT will play a key role. Companies must expand on business continuity plans, which typically assume that disasters will be regional and affect infrastructure, to deal with a disaster that is global and affects staff resources.

“You can easily modify your existing business continuity plan to handle this type of disaster,” says Kathy Sgroi, manager of service management in the information services division at United Parcel Service.

Preparations include cross-training IT staffers to handle critical functions such as hardware maintenance.

Beyond that, the IT department can deploy e-learning tools, expand remote access gateways to support more telecommuters and beef up intranet portals, videoconferencing, Web conferencing and other communication channels that will keep employees informed during an outbreak.

At Deloitte, Ainslie has used “webinars” to educate executives on the threat and how they should respond.

“The two cornerstones of any plan are being able to communicate and [being able] to receive and distribute timely and accurate information to decision-makers,” says Brent Woodworth, a manager with the crisis response team at IBM Global Services.

Wayne Rawlins, national medical director and clinical lead for pandemic planning at Aetna, says the company’s pandemic plan has been “layered” into its crisis management plan.

The insurer recently conducted a full-scale simulation of its plan and is ready to operate its data centers at 50 per cent staffing levels, says Dana Bennett, head of IT strategy, planning and business architecture.

Aetna will use its intranet portal and an interactive voice-response system to communicate information to employees and its clients during an emergency, and it has deployed e-learning courseware for pandemic education.

About 70 per cent of employees are already set up for some level of remote access, Bennett says.

Aetna is also ramping up its remote access gateways, which can support simultaneous network access for IT workers and the 10 per cent of its workforce who are full-time teleworkers.

Globalization could magnify a pandemic’s effect on businesses, especially in the US, says Ainslie. “We’re in a just-in-time economy. Everything is offshored and outsourced,” he says.

“Thought ought to be given as to whether and when to increase stockpiles of critical equipment,” says Deloitte’s Ross.

Michael Rasmussen, an analyst at Forrester Research, says IT should plan now for supply chain disruptions. “Spare parts and [things like] new laptop shipments could be restricted to some degree. Even backup tapes and off-site storage could become a challenge” as transportation bottlenecks emerge, he says.

ASIAN PRODUCTION HUBS

Personnel shortages won’t just affect low-level staffers. IT decision-makers could suddenly become unavailable.

One option is to predefine task orders or procedures, such as procurements, that normally need several layers of approval, says Woodworth. “If you can get those preapproved ... it will be easier to get the things you need in a disaster,” he says.

Companies like Kichler Lighting could feel the effects of a pandemic well before it hits US shores. A failure of Kichler’s back-office IT systems won’t stop the business right away, but the firm may not have any products to ship.

“Most of the company’s products are manufactured in Asia. If it hits [there], we’re pretty much going to have to shut down,” Schindler says.

At UPS, the data center is an integral part of operations. “If our computer systems don’t run, scanners in our locations all over the world won’t work. Our revenue stops because our business stops,” says Sgroi.

Like most large companies, UPS can remotely manage most aspects of data center operations, with the exception of hardware maintenance. But UPS also has a plan for moving workloads. If a major site in Asia or elsewhere goes offline, the company’s plan calls for diverting data to another location, which must have enough capacity to take on the added workload, Sgroi says.

UPS is also adding a Web-based absenteeism application to help managers during a crisis. “During a pandemic, we would need better control over how many people are in and out of the office. This doesn’t exist today,” Sgroi says.

Ainslie says it isn’t enough to have backup power. He’s looking at how to keep running for extended periods without utility power or access to fuel for backup generators. “You have to have enough [fuel] for an extended period of time, if practical,” he says.

Sgroi is confident that IT can function with an absentee rate of 25 per cent, but she says a rate of 40 per cent would require additional steps. Even Deloitte, which advises clients on pandemic planning and has invested considerable time and effort in its own plans, isn’t ready for a 40 per cent absenteeism rate. “We still have a lot of work to do,” Ross says.

Organisations that have outsourced parts of their IT operations should also take a hard look at their collocation facilities and other outsourced IT services, says Rasmussen. “You need to be working with them to make sure you have a right to an audit. Look at their business continuity plans and what processes are in place to execute those plans,” he suggests.

LIMITATIONS OF REMOTE ACCESS

Although telecommuting can help some staffers continue to work during a pandemic, in some cases it just isn’t practical.

At Kichler Lighting, where IT staffers are already engaged in an ERP rollout, a project to support remote access for teleworkers is at least 24 to 36 months away, says Schindler.

Aetna isn’t counting on remote access during a pandemic. Bennett is concerned that users working from home might have extremely slow Internet connectivity—or no last-mile connectivity at all—if their Internet service providers aren’t capable of handling the expected surge in usage.

The bigger problem, however, is that many job functions simply can’t be performed remotely. “Sending everyone home to telework isn’t viable in our business,” Bennett says.

Instead, Aetna is focusing on reducing workplace risks, by using its intranet and e-learning systems to train employees on practices such as “social distancing” (staying three feet away from others), the use of protective masks and gloves, and environmental cleaning.

At other businesses, remote access will be crucial. “The principal role of the IT team has been to enhance our remote working capability,” says Dennis Jobin, managing director of the business continuity planning division at The Bank of New York Co. The bank is also ramping up its internal Web site to support more concurrent users.

MANAGING SECURITY RISKS

Security is a concern. Businesses may want to distribute laptops in advance to ensure that endpoint devices coming into the virtual private network are properly secured, says Ross.

Bank of New York has a VPN but is in the final stages of choosing a thin-client, desktop application virtualization technology that’s capable of securely supporting remote access by a large population of users working from home.

The new system will securely support any computer equipped with a browser, thus eliminating worry about the security of home computers or supplying company laptops. Configuration and management will all occur on the back end. “The solution we choose will minimize or eliminate any visits to people’s homes,” says Jobin.

Cross-training employees can help the business cope with skills shortages by making it possible for remaining employees to get critical tasks done, but training must occur before a pandemic strikes. “That has to happen now. You can’t wait,” says Ross.

But cross-trained employees taking on new roles will need access to different parts of the company’s computer systems. “Which applications you can use, which data you have access to, will change,” Ross says, and identity management tools will be critical to such provisioning efforts.

Ultimately, dealing with a pandemic is a problem that must be coordinated at the executive management level through a cross-functional team. “IT is not the problem, nor the full solution,” says Rawlins.
But it is part of the solution. And in a true emergency, information systems might just be the glue that keeps employees in touch—and holds the organisation together.
 

JPD

Inactive
Farmers slaughter remaining poultry in Czech village hit by bird flu

http://www.iht.com/articles/ap/2007/06/22/europe/EU-GEN-Czech-Bird-Flu.php

PRAGUE, Czech Republic: Farmers slaughtered all remaining poultry in the village of Tisova on Friday, after confirmation a day earlier that hundreds of birds at a turkey farm had died of the H5N1 bird flu virus, officials said.

On Thursday, tests confirmed that 1,800 turkeys at the farm in the eastern Czech Republic died of H5N1. Tisova is 100 kilometers (60 miles) east of Prague.

The farm's other 6,000 turkeys were slaughtered immediately. About 1,000 hens and ducks kept by other small farmers in the area were ordered to be killed Friday.

"All the poultry in the village is being slaughtered today," said Zbynek Semerad, a spokesman for the Czech veterinary authority.

He said an EU ban on poultry exports from the affected region was in force as of Thursday.
 

JPD

Inactive
Indonesian bird flu Tamiflu resistant

http://www.theglobeandmail.com/serv...fluu0621/BNStory/specialScienceandHealth/home



Canadian Press

June 21, 2007 at 9:07 PM EDT

TORONTO — An Australian researcher says H5N1 avian flu viruses from Indonesia are markedly less susceptible to the antiviral drug Tamiflu than a previous line of the H5N1 family of viruses.

Jennifer McKimm-Breschkin says laboratory testing shows the viruses from Indonesia are 20 to 30 times less susceptible to the drug as compared to H5N1 viruses that circulated in Cambodia a couple of years ago.

Dr. McKimm-Breschkin, who's attending a conference on infectious diseases in Toronto, says the findings are not good news.

And she says they may help to explain the high death toll from H5N1 in Indonesia, where 80 of 100 patients have died of the disease.

A scientist from the World Health Organization says it's not clear what the impact of the reduced susceptibility to Tamiflu means for people from that part of the world who become infected with the virus.

Dr. Frederick Hayden says a lot of factors can have an impact on whether oseltamivir treatment of H5N1 patients is successful, including how much time passes between infection and the start of drug therapy.
 

JPD

Inactive
Togo confirms H5N1 bird flu virus at poultry farm

http://africa.reuters.com/top/news/usnBAN241777.html?rpc=401&

Fri 22 Jun 2007, 11:29 GMT
[-] Text [+]

By John Zodzi

LOME (Reuters) - Tests have confirmed an outbreak of the deadly H5N1 birdflu virus at a poultry farm in the West African country of Togo, Agriculture Minister Yves Nagou said on Friday.

Samples from the semi-industrial farm at Sigbehoue, about 45 km (28 miles) east of the capital Lome, had been sent for laboratory tests in neighbouring Ghana after the sudden mass death of poultry at the site.

"It is confirmed. The results from the laboratory in Accra have detected the H5N1 type of virus," Nagou told Reuters. Preliminary tests in Togo had already indicated the presence of

H5N1.

Togo became the seventh West African country hit by the H5N1 virus after Ghana, Ivory Coast, Burkina Faso, Niger, Cameroon and Nigeria.

The worst affected country in West Africa, Nigeria, reported sub-Saharan Africa's only confirmed human death from H5N1 early this year.

The farm in Sigbehoue, close to the border with Benin, received a consignment of chicks in February from Ghana, where the deadly strain of avian flu was detected in early May, the minister said.

Ghana imposed an export ban on poultry last month.

The farm has been sealed off and the remainder of its poultry culled and incinerated after about 2,000 chickens out of a total stock of 3,000 had died in two days, officials said.

A meeting of 14 francophone African countries in the Malian capital Bamako on Thursday agreed on a six-month roadmap for tackling the epidemic focused on the management of poultry.

The H5N1 virus mainly affects birds, but experts fear it could change into a form easily transmitted from person to person and lead to a pandemic.

So far, most human cases can be traced to direct or indirect contact with infected birds and hundreds of millions of birds have died or been culled.

Bird flu has been spreading through southeast Asia, killing two people in Vietnam this month, the first deaths there since 2005.

Globally, the H5N1 virus has killed nearly 200 people out of over 300 known cases, according to the World Health Organisation.
 

Bill P

Inactive
Scientists Fear H7N2 Influenza a Threat to Human Health

According to a June 19, 2007, Science Daily report, scientists in the United Kingdom believe that, in addition to the H5N1 influenza strain which has infected at least 313 people and killed 191, a second strain of avian flu (H7N2) may pose a significant threat to humans.1 At the Options for the Control of Influenza VI conference held in Toronto on June 19, Jonathan Nguyen-Van-Tam, a senior lecturer at London’s Public Health Laboratory Services, described an H7N2 outbreak on small poultry farms in Wales which occurred in spring 2007.1

According to Nguyen-Van-Tam, poultry on a number of small farms in Wales became sick and tested positive for H7N2 avian influenza in May 2007. Four people who had contact with the sick birds also tested positive for H7 influenza, and 3 of them were hospitalized for respiratory illness. “One person was a candidate for intensive care before he finally came around,” Nguyen-Van-Tam told Science Daily.1

During the course of the outbreak, which lasted from May 1 through May 17, 369 individuals who had contact with sick birds or patients were treated with the antiviral drug Tamiflu®. While “serology tests are still underway,” scientists have yet to find evidence in this outbreak of human-to-human transmission of the virus.1

According to the Science Daily report, the severity of human illness associated with this outbreak may indicate that H7N2, which was previously considered of “little human risk” may be as “equally formidable” and difficult to contain as H5N1, and “does pose a real danger to people.” Nguyen-Van-Tam encouraged the international healthcare and scientific communities to “reconsider the H7 strain on the basis of this outbreak” in Wales.1

Crystal Franco

References

Susman E. Analysis: bird flu fears reignited. Science Daily. June 18, 2007. Available at: http://www.sciencedaily.com/upi/ind...19-14351400-bc-canada-newbirdflu-analysis.xml. Accessed June 22, 2007.
 
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