2/24/07-3/2/07|Weekly Bird Flu Thread: Afghan Health Confirms Deadly Bird Flu

JPD

Inactive
Afghan Health Ministry Confirms Deadly Bird Flu Virus

http://www.voanews.com/english/2007-02-23-voa55.cfm

By VOA News
23 February 2007


Afghanistan's Health Ministry has confirmed the presence of bird flu in eastern Nangarhar province.

Health Ministry Deputy Faizullah Kakar told VOA that the deadly H5N1 strain of bird flu virus was confirmed by officials Friday. A team of doctors also suspected a human case of bird flu in the region but discovered the person was suffering from malaria.

The area has been quarantined, and the Health Ministry says officials have begun an information campaign.

Earlier this week, Afghan authorities ordered the slaughter of birds in both Nangarhar and Kunar provinces, suspecting an outbreak of bird flu.

Last year, Afghanistan discovered cases of the H5N1 virus in birds, but not humans.

The deadly strain of the bird flu virus has killed at least 160 people worldwide since 2003.
 

JPD

Inactive
U.S. Officials Offer Pandemic Flu Aid in Egypt, Switzerland

http://usinfo.state.gov/xarchives/d...=February&x=20070223170243lcnirellep0.3083612

Health agency makes 2,000 influenza virus genomes available worldwide

By Cheryl Pellerin
USINFO Staff Writer

Washington -- During a five-day visit to Cairo, Egypt, and Geneva, officials from U.S. agencies offered help to the government of Egypt in controlling the spread of avian influenza among birds there, and met with World Health Organization (WHO) leaders to discuss international cooperation in preventing and responding to avian and pandemic influenza.

In Cairo, Ambassador John Lange, the Department of State's Special Representative for Avian and Pandemic Influenza, led a team of representatives from six U.S. government health, agriculture and international assistance agencies to meet with Egypt's ministers of health and agriculture.

"[We] came away very impressed by the government of Egypt's efforts," Lange said during a February 23 press briefing at the U.S. Mission to the United Nations in Geneva.

Lange commended the minister of health, Dr. Hatem el-Gabali, for "the transparency that the government of Egypt has shown" in sharing samples of the nation's avian flu viruses with the world. Egypt has reported 22 human cases of avian flu and 13 deaths.

The U.S. ambassador also commended Minister of Agriculture Amin Abaza for developing an effective program of vaccination for poultry in the commercial sector.

"We look on this not as merely a health or agriculture issue," Lange said. "It's broader, and involves the totality of governments. [The U.S.] national implementation plan tasks all U.S. government departments and agencies with acting and preparing for a possible pandemic."

WHO and the Food and Agriculture Organization also are providing support to Egypt, he added.

GLOBAL REPONSE

In Geneva, Lange said, he and Dr. David Bell, coordinator of the Influenza Unit in the Office of Global Health Affairs for the U.S. Department of Health and Human Services, met with WHO Director-General Dr. Margaret Chan and Dr. David Heymann, WHO acting assistant director-general for communicable diseases.

One focus of the discussion, Lange said, "was how this global threat requires a global response. In that regard, we discussed the critical importance of sharing of samples [of avian flu viruses in each country] in order to do risk assessment."

WHO needs samples of the virus to follow its path around the globe and assess the risk that the virus could mutate to become easily transmissible among people, he added.

"We also discussed the need to facilitate broader and more equitable regional distribution of production capacity for influenza vaccine," Lange said.

Earlier in February, Indonesian officials said they would stop sharing virus samples with WHO unless an agreement could be reached that would guarantee the country access to affordable vaccines against avian influenza. On February 16, Siti Fadillah Supari, Indonesia's minister of health and WHO's Heymann released a statement saying Indonesia would again share avian flu viruses with the WHO Network of Collaborating Centers for Influenza. Indonesia has not yet begun sharing samples with WHO, which will meet with Asian nations in March to discuss access to vaccines for all countries.

"It's simply a matter of working out with the governments of the world and with the leadership of the World Health Organization the ways in which we will proceed in this regard," Lange said.

GENETIC BLUEPRINTS

In the United States, scientists from the National Institutes of Health (NIH) and its National Institute of Allergy and Infectious Diseases (NIAID) announced February 21 that genetic blueprints of more than 2,000 human and avian influenza viruses taken from samples around the world now are available in a public database to scientists everywhere for use in developing new vaccines and therapies.

The effort, coordinated by the NIH-funded Influenza Genome Sequencing Project, began in 2004.

"This information will help scientists understand how influenza viruses evolve and spread," NIH Director Dr. Elias Zerhouni said in a February 21 statement, "and it will aid in the development of new flu vaccines, therapies and diagnostics."

The project has been carried out at the NIAID-funded Microbial Sequencing Center, which will sequence more flu strains and samples and make all sequence data freely available to the scientific community and the public through GenBank, an Internet-accessible database of genetic sequences maintained by the National Center for Biotechnology Information at NIH's National Library of Medicine, another major contributor to the project.

Collaborators on the project include the U.S. Centers for Disease Control and Prevention; the World Organization for Animal Health/Food and Agriculture Organization Reference Laboratory for Newcastle Disease and Avian Influenza in Padova, Italy; and Canterbury Health Laboratories in Christchurch, New Zealand.

Access to the influenza virus sequence data is available at NIAID's Influenza Genome Sequencing Project or GenBank.

The full text of Lange's opening statement and an audio link to his speech can be found on the U.S. Mission to the United Nations in Geneva Web site.

For more information on U.S. and international efforts to combat avian influenza, see Bird Flu (Avian Influenza).

(USINFO is produced by the Bureau of International Information Programs, U.S. Department of State. Web site: http://usinfo.state.gov)
 

JPD

Inactive
Border security, immigration, terrorism dominate trilateral talks among ministers

http://www.iht.com/articles/ap/2007/02/24/america/NA-GEN-Canada-US-Mexico.php

OTTAWA: Though promoting prosperity was at the top of the agenda when some of North America's most powerful cabinet ministers gathered in the Canadian capital, security, immigration and the threat of terrorism also dominated the unprecedented trilateral talks.

Nine foreign and security ministers from Canada, Mexico and the United States were in Ottawa for the Security and Prosperity Partnership meeting Friday, including U.S. Secretary of State Condoleezza Rice, Mexican Foreign Secretary Patricia Espinosa and U.S. Homeland Security Secretary Michael Chertoff.

The talks were a lead-up to a meeting of the countries' leaders this August in Canada.

They reviewed an exhaustive 63-page report from the North American Competitiveness Council on how to streamline border crossings, harmonize regulatory standards and improve the supply and distribution of clean energy sources. They also discussed ways in which to deal with a global bird flu pandemic, natural disasters, organized crime and drug trafficking.

But after a full day of closed-door meetings, when they addressed joint news conferences, the issues of security, illegal immigration and how each country is dealing with the perceived threat of terrorism dominated the questions from reporters.

Rice was asked if she discussed the sensitive case of Canadian engineer Maher Arar with her Canadian counterpart, Foreign Minister Peter MacKay.

Canada and the United States are at odds over the treatment of Syrian-born Arar, who was secretly nabbed by U.S. officials to Damascus for interrogation about links to terrorism. He spent a year in a cell and was tortured, before the Syrians shipped him home to Canada.

Though cleared by a Canadian federal inquiry and given a formal apology and multimillion dollar settlement by Ottawa, Washington refuses to comply with Canadian demands that Arar be removed from its no-fly lists.

"Well, we respect the decision of the Canadian government concerning Mr. Arar," Rice responded. "The United States, of course, makes decisions based on information that we have and based on our own assessment of the situation."

MacKay said the two sides, at this point, "agree to disagree."

The talks were partially overshadowed by a ruling earlier in the day by the Supreme Court of Canada, which overturned as a violation of human rights an anti-terrorism provision that allows the government to indefinitely detain foreign terror suspects without charge or trial.

MacKay insisted the ruling did not impact the trilateral meetings, and reiterated Canada's commitment to protected North American borders from terrorism.

"This ruling does include, I understand, a one-year period in which the government will have the opportunity to react and to respond accordingly," he said. "Clearly, we will take the time to do just that. But in the meantime, we will very much remain vigilant in our pursuit of measures necessary to protect Canadian citizens."

The United States, Canada and Mexico, under the North American Free Trade Agreement, enjoy the largest trading partnership in the world. With a combined gross domestic product of US$15 trillion (€11.4 trillion), the three nations exchange goods and services worth nearly US$1 trillion (€760 billion) and see about 500 million legal border crossings a year.

Some critics believe the Bush administration has put too great an emphasis on border security and not enough on the economic alliance. A Mexican journalist told Rice that this was the growing perception in his country, to which she disagreed.

"I think that if you look at everything from NAFTA on, including our extensive trade relationships, our extensive economic relationships, you can see that the United States and Mexico have been deeply concerned about one another's prosperity," she said. "But as the president has said, ultimately when one talks, for instance, about the issues of immigration, we want very much to see a Mexico in which Mexicans can find work and can take care of their families in Mexico."

Mexico wants Washington to usher through reforms to create a guest worker program, provide a legal path for millions of Mexicans living in the United States and allow for the reunification of families split by immigration laws. U.S. President George W. Bush supports giving Mexican migrants temporary work visas, but has failed to win support in U.S. Congress.

There are an estimated 11 million Mexican-born people living in the United States, and about 6 million of those are believed to be undocumented.

Mexico's Foreign Secretary Patricia Espinosa said newly elected Mexican President Felipe Calderon was approaching his first 100 days in office.

"I would like to say that the issues dealt with in this meeting coincide fully with the priorities that the president of the republic established as the objectives of his mandate," said Espinosa.

Calderon, a career politician in the conservative National Action Party, narrowly won election last year on promises to smash drug gangs blamed for killing more than 2,000 people in 2006, many in execution-style killings and gruesome beheadings.

Since taking power in December, the president has sent more than 24,000 soldiers and federal police to areas ravaged by drug violence. He has also extradited four alleged drug kingpins to the United States where they could be given life sentences in high-security prisons.

Chertoff was full of praise for the new Mexican president.

"I have to say it's very, very inspiring to see how vigorously President Calderon has moved, even in his brief term in office, to assert security controls when there are violations of the law," Chertoff said.
 

JPD

Inactive
NIGERIA: FAO warns more effort needed to check worsening bird flu crisis

http://www.irinnews.org/Report.aspx?ReportId=70281

LAGOS, 20 February 2007 (IRIN) - At the Costain live animal market in Nigeria’s main city of Lagos chickens, turkeys and geese are still crowded together in the portable coops they arrived in from upcountry. Teenage boys helping buyers kill, clean and cut up the birds still do so with knives and bare hands, unprotected by gloves or face masks.

More than one year after Nigeria reported sub-Saharan Africa's first cases of the deadly H5N1 avian flu virus and one month after the illness claimed its first human life in the country, little has changed in the way birds are handled or slaughtered.

But old habits need to change and control measures must be improved in markets and on farms if Nigeria is to the curb the worsening spread of the virus, the Food and Agriculture Organisation (FAO) said on Tuesday.

Poultry in at least 19 of Nigeria's 36 states have been infected by bird flu, according to the government. The FAO said its recent mission to Nigeria found that the virus was still spreading, with the most probable means being traders moving poultry across the country.

The agency warned that neighbouring countries were at risk and said urgent surveillance measures were necessary to stop the disease from spreading across Nigeria’s borders into Benin, Niger, Chad and Cameroon.

“The first confirmed case of H5N1 infection in humans in Nigeria shows that there is a continuing danger of human exposure to the virus from high-risk practices, such as handling sick or dead chickens, and especially from unsafe slaughtering of poultry at home or in markets,” said Joseph Domenech, chief veterinary officer of FAO, in a statement.

The FAO sent a team to help Nigeria, Africa’s most populous country, after local health authorities reported that a 22-year-old woman had died on 17 January from avian flu. Subsequent tests by the World Health Organisation (WHO) confirmed the Nigerian diagnosis, prompting investigation of the woman's mother who had died weeks earlier.

Tony Forman, leader of the FAO mission to Nigeria, said initial tests did not show the victim's mother also died of bird flu, although WHO and the US Centres for Disease Control were conducting further investigations. The FAO team was also unable to determine the exact source of the bird flu infection beyond the fact that it probably came from live chicken the young woman bought from a Lagos market just before Christmas.

“We believe the source of the virus was poultry purchased from a Lagos market,” Forman told IRIN. “It's been a long time now. The prospect for determining where this (virus) came from is now virtually impossible,” he said, citing wild migratory birds and legal and illegal imports as possible sources.

The major challenge facing Nigeria, Forman said, was to quickly obtain information about where the virus was and where it might be spreading in order to curtail it.

Despite the government's efforts, experts say more still needs to be done to effectively curtail the spread of the virus that scientists fear could mutate into a strain that could be easily transmissible between humans and cause a global pandemic. So far, 167 people have died from avian influenza worldwide.

“I think the government is doing a good job,” said Forman of the FAO. “But they need additional support to get a better control of this disease.”
 

JPD

Inactive
New bird flu outbreak in Turkey suspected

http://www.ntvmsnbc.com/news/400870.asp

The governor of Burdur orders samples taken from a number of chickens that had died to be tested.

Güncelleme: 15:35 TSİ 23 Şubat 2007 Cuma

BURDUR - Two children from the southern Turkish province of Burdur were hospitalised Friday after possibly contracting avian flu.

The parents of the children, from the Aglasun district of Burdur took their one year old baby to a health centre after the child developed a high fever and told the doctor that their two children had eaten eggs from three chicken they had in their backyard.

Both children, the elder being three years old, were sent to Burdur state hospital where blood samples are taken to be tested bird flu.

Although bird flu has confirmed among poultry in few villages in southeastern Turkey, no human cases have been reported.
 

JPD

Inactive
Egyptian child recovers from bird flu - agency

http://www.alertnet.org/thenews/newsdesk/L24415627.htm

CAIRO, Feb 24 (Reuters) - A five-year-old Egyptian boy who tested positive for bird flu has recovered, the official Middle East News Agency (MENA) reported on Saturday.

Mohamed Ahmed Suleiman recovered after treatment with frontline antiviral Tamiflu and was allowed to go home, MENA quoted Yusri Ragab, director of the Cairo hospital where the child was treated as saying.

Suleiman was the 22nd case to test positive for the H5N1 virus in Egypt, which has the largest bird flu cluster outside Asia. Of the 22 cases, 13 have died.

Most people infected in Egypt had been in contact with live birds kept at home. Bird flu initially caused panic across the country and did extensive damage to the poultry industry, although the sector has largely recovered.

World Health Organisation officials have said a delay in reporting symptoms in Egypt, where many people keep poultry at home, made the virus harder to fight.
 

JPD

Inactive
Bangladesh

Smuggled chicks burned in Satkhira

http://www.thedailystar.net/2007/02/25/d70225070497.htm

Our Correspondent, Satkhira

At least 993 layer chickens smuggled from a neighbouring country were burned in Satkhira on Friday on suspicion of their being affected with bird flu virus.

District Poultry Traders' Association President Noor Islam said a group of unscrupulous traders is smuggling chickens from a neighbouring country.

Bangladesh Rifles (BDR) and police sources said acting on a tip-off, BDR seized the chickens from Basantapur in Kaliganj upazila on February 21 while those were being smuggled into the country. The smugglers escape. The seized chickens were kept at local customs warehouse in Basantapur in Kaliganj upazila.

As per a decision of the local administration taken at a meeting at Kaliganj Upazila Nirbahi Officer's office, the chickens were burned near Basantapur border outpost, police said.
 

JPD

Inactive
Bird flu fears — Marghzar Zoo staff, birds to be tested every 3 months

http://www.dailytimes.com.pk/default.asp?page=2007\02\25\story_25-2-2007_pg11_2

ISLAMABAD: The employees of Marghzar Zoo and the birds housed there will have to undergo tests for detecting bird flu every three months to prevent the reoccurrence of any sudden outbreak of the disease.

CDA Chairman Kamran Lashari said this while speaking at a meeting of the authority to discuss the issue of closure of the zoo after 20 birds died due to the H5NI avian influenza virus and forced health authorities to test all the other birds and employees for the disease. Eight of the employees tested negative for the strain, according to test results announced on Friday.

The CDA chairman took stern notice of the continued closure of the zoo and directed the management to reopen it within two days. He asked the management to start testing birds and their caretakers at regular intervals - every three months - so that the zoo would not have to be closed again. The meeting appreciated the response of health authorities in the aftermath of the outbreak to stop the further spread of the virus.

Meanwhile, Mazhar Hussain, the CDA’s environment wing director general, said in a statement that authorities concerned, including the zoo’s management, had been informed of the directives issued during the meeting. He said that arrangements for reopening the zoo were in the “final stage”, adding that the zoo would be opened within two days. The zoo has 250 birds and 88 other animals.

QAU students directed to get registration receipts: The Quaid-i-Azam University examination controller has directed students to ensure their participation in the upcoming convocation by obtaining registration receipts Sunday (today). The Quaid-i-Azam University will hold its fourth Convocation on March 13 in the Convention Centre, Islamabad. According to a statement issued by the controller, students will only be allowed to enter the Convention Centre if they have the registration receipts with them. He said that MPhil, MSc students of academic year 2004-06 and PhD students from 1996 to 2006 would be awarded certificates during the convocation.

CDA to change contractor of delayed road project: The Capital Development Authority (CDA) is considering changing the construction firm building a service road from sectors G-8 to G-10. Differences have arisen between the authority and the contractor and the issue has been taken to a local court. The court has summoned both the contractor and CDA officials. Official sources said the CDA had earlier given the contract to the Al-Khan Construction Firm that had to complete the project within a year. However, the firm could only complete 25 percent of the work though 16 months have already passed. The firm also hired the services of another firm to complete the project in time, but both of them also developed differences. The sub-contractor then moved court over the issue.

Survey of 23 dilapidated municipal dispensaries starts: The Rawalpindi District Health department has started a survey of 23 municipal dispensaries in need of repairs. The survey results will be sent to the district government for obtaining funds for the repair and reconstruction of these dispensaries. District Nazim Raja Javed Akhlas had earlier issued Rs 2 million for similar projects. The district health department officers have demanded more funds for improving the health sector. online
 

JPD

Inactive
Pandemic flu ‘very challenging’

http://www.timeswv.com/local/local_story_056011310.html

If it strikes, as much as 40 percent of work force might have to stay home
By Mary Wade Burnside
Times West Virginian

FAIRMONT — If a pandemic flu epidemic strikes, as much as 40 percent of the work force might have to stay home because of illness or the need to take care of family members.

That would include hospital and emergency workers, thereby depleting the segment that would be needed the most during a time of crisis.

Not only would some people with the flu go without professional medical treatment, but even such incidents as car accidents might have to go untreated by police or an emergency squad.

“There is a strong possibility that if we just have half of our staff, that we would have to have some people take care of themselves,” said Chris McIntire, director of emergency services in Marion County. “Believe me, we would do the best we possibly can of getting help to everybody.”

McIntire also serves as the chairman of Marion County’s Local Emergency Planning Committee, which meets monthly. The group plans for potential events including natural disasters and terrorist attacks, but recently, pandemic flu has been a primary focus. An emergency plan is available for public viewing at the Marion County Commission’s office, and, McIntire said, eventually the document should be available via the Internet.

Part of the plan would be for as many people as possible to stay at home, or “shelter in place,” in an effort to prevent the spread of the pandemic.

“That’s the major focus right now,” McIntire said. “If you think about it, there’s no place with 58,000 beds in Marion County. At home, there’s someone to take care of the sick. There’s food at the house and shelter. It’s only logical to keep people out of harm’s way.”

It’s been nearly 100 years since the 1918 flu pandemic killed an estimated 50 million to 100 million people worldwide, and some health officials say it’s not a matter of if but when another one will strike. The World Health Organization warns that a substantial risk exists for a pandemic flu to emerge in the next few years.

So far, the bird flu, which has jumped from animals to humans but has yet to be easily transmitted from human to human, is considered a likely candidate to be the virus that causes a pandemic, but no one knows for sure.

“Pandemic flu is going to be a very challenging event,” said Jamie Moore, the regional all hazards coordinator.

Moore works out of the Monongalia County Health Department in Morgantown, but his scope includes not only that county, but also Marion, Harrison, Taylor, Preston and Doddridge counties.

“The problem with a pandemic is being that it’s a new strain of virus, we won’t have immunity,” Moore said. “So it has a pretty devastating effect on the body when you get it. Being that no one has immunity, it goes through the population pretty quickly.”

According to www.birdflufacts.com, a vaccine against the deadly H5N1 virus of bird flu is under development, but has not been tested and would not be available until after a pandemic begins because the new virus has to emerge before it can be included.

Even though there are a lot of unknowns about a pandemic, based on the 1918 flu episode, health officials can come up with potential scenarios. They are bleak, with death expected on a scale that might be difficult to comprehend.

“Nobody is real certain,” McIntire said. “In England, where they are having cases of it, they are estimating that it could affect 7 percent of the population, and 2 percent of that could be fatalities. That’s a large number when you are talking a county of 58,000, to have something of that magnitude. It would send shockwaves across the entire county.”

In the case of a pandemic, Moore of Monongalia County envisions a scenario in which the first wave of the disease would last for about eight weeks.

“It could vary,” he said. “And then it kind of dies down. Then it comes back within another month or so.”

And while the nation watched the devastation of Hurricane Katrina, at least the residents of Louisiana were able to get outside help from the rest of the country. That will not be the case with a pandemic.

“The ability of folks to send help is going to be limited,” Moore said.

Eventually, vaccine would be manufactured and administered, and the population would begin to build up immunity.

In 2007, pandemic flu has been the topic of discussion at two Fairmont events, including an informational summit at Fairmont State University in January and a regional meeting of area county health departments earlier this month.

In the case of an outbreak, the Marion County Health Department, acting with guidance from the state and the Centers for Disease Control and Prevention (www.cdc.gov), would be the entity that tracks the illness and provides leadership to the community.

But before an outbreak might occur, health officials encourage families to be prepared to stay at home with supplies for food, water and other items.

A Web site, http://pandemicflu.gov/plan/individual/familyguide.html, provides a comprehensive list of items that people should have on hand, including two weeks of nonperishable food and two weeks of water, which would be one gallon of water per person per day for consumption, food preparation and sanitation.

“We’re basing this on the assumption that up to 40 percent of the work force might not be working, maybe greater,” said Lloyd White, the administrator of the Marion County Health Department.

That number could include power and water plant employees, which could endanger utilities.

“We don’t know if we’ll have water or electricity or other utilities because of these unknown factors, so it’s good to plan for that,” White said.

The county has a grant from the CDC that includes $22,000 for pandemic flu, said Tammy Hare, an epidemiologist with the Marion County Health Department. Of the grant, $4,000 has gone to the Local Emergency Planning Committee, which is stockpiling supplies, including 20,000 specialized N95 masks for responders.

Also, the Marion County Board of Education has gotten $1,000 to buy supplies, including thermometers, “so they can take kids’ temperatures and see whether or not they should be sent home,” Hare said.

Health surveillance is an important part of dealing with a pandemic, health officials agree, and even though the disease will be different than seasonal influenza, if people get their annual flu vaccines, it helps in the long run.

“If you do get sick and you know it’s not regular flu, then you eliminate that as a possibility,” said Janet Crigler, the infection control coordinator at Fairmont General Hospital. “Plus, we don’t want people coming in with seasonal flu where there is avian flu.”

In the case of a pandemic, the expectation is that the hospital would become too crowded to deal with everyone who is sick, whether with the flu or with the everyday sicknesses that will not just go away because of the crisis. People with the flu would remain at home and be cared for by their relatives, who would try to keep them hydrated and deal with the illness as best as possible.

“The most important thing people can do is to learn what they need to have at home as far as supplies and learn good home care,” Crigler said. “Sometimes, the hospital is not the best place to be.”
 

JPD

Inactive
Kuwait confirms 20 cases of avian flu in birds including falcons and chickens

http://www.iht.com/articles/ap/2007/02/25/africa/ME-GEN-Kuwait-Bird-Flu.php

KUWAIT CITY: Kuwait has confirmed 20 cases of the deadly avian flu in birds including falcons, chickens and turkeys, a spokesman for the Health Ministry said Sunday.

Ahmed al-Shatti said there were no human cases and an emergency plan has been activated.

This small oil-rich state last confirmed case of the deadly H5N1 strain of the virus was in 2005 when officials discovered the disease in a flamingo.

Since it began ravaging Asian poultry farms in late 2003, the H5N1 strain has killed at least 167 people worldwide, according to the World Health Organization.

Although it remains difficult for humans to catch, health authorities across the world are monitoring the strain out of concern it could mutate into a form that easily spreads from person to person, sparking a pandemic.
 

huntersdada

Membership Revoked
Thanks JPD for staying on top of this for us.

Since it began ravaging Asian poultry farms in late 2003, the H5N1 strain has killed at least 167 people worldwide, according to the World Health Organization.

167 divided by 5 = 33.40 persons killed annually from this avian influenza. I would not dare to take away from the seriousness of these deaths and probably more, but they hardly constitute a pandemic. It just seems to me that someone is dead set on the world having a pandemic from this...at some point. Yet, thank the Lord, it hasn't happened yet.

OTOH, BF in Afghanistan, our soldiers over there, coming home, bringing things with them that they didn't take with them, sure makes for some scary scenarios.

:whistle:
 

adgal

Veteran Member
huntersdada said:
OTOH, BF in Afghanistan, our soldiers over there, coming home, bringing things with them that they didn't take with them, sure makes for some scary scenarios.

I was just thinking that same thing - wasn't the 1918 Spanish Flu brought here by soldiers returning from the war?
 

JPD

Inactive
Russia finds bird flu in new region, suspects more

http://www.zeenews.com/znnew/articles.asp?aid=356502&ssid=28&sid=ENV

Moscow, Feb 25: Russia confirmed another outbreak of the highly pathogenic H5N1 strain of bird flu, potentially dangerous to humans, on a farm in a southern region on Wednesday and suspects two more outbreaks on farms near Moscow.

Alexei Alexeyenko, spokesman for animal and plant health watchdog Rosselkhoznadzor, said the H5N1 strain was identified in the republic of Adygeya, a region in the North Caucasus.

Bird deaths also have been registered at farms in Dmitrov district, part of Moscow region, and Borovsk district in the Kaluga region, which borders the Moscow region to the south.

Alexeyenko said he expected confirmation of the presence of the virus in these regions within the next two days.

"It looks like it`s H5N1 again, as the pattern appears to be the same as in the previous cases," he said.

Outbreaks of H5N1 have so far been confirmed in Moscow`s Sadovod pet market and in five districts of the Moscow region -- Domodedovo, Odintsovo, Podolsk, Naro-Fominsk and Taldom.

Alexeyenko said he expected confirmation before the end of Wednesday that H5N1 was responsible for outbreaks identified earlier in two more districts of the Moscow region -- Volokolamsk and Ramenskoye.

Bureau Report
 

JPD

Inactive
Laos

First human case of bird flu suspected

http://www.vientianetimes.org.la/FreeContent/FreeContent_First human.htm

The transmission of avian influenza to a human host is now suspected for the first time in Laos , but more scientific research is being conducted to confirm it as fact, the government announced on Sunday.


Minister of Public Health, Dr Ponmek Dalalay, said at the emergency press conference that the patient in question was

a 15-year-old student from Dongsavath village, Sisattanak district, Vientiane , where bird flu broke out two weeks ago.

“She went for treatment at Setthathirath hospital on February 15. She was sick, with a headache and pain in some parts of her

body. She also had a runny nose and cough. All of these things can indicate the common cold,” the minister said.

Dr Ponmek added that her parents sent her for treatment in a hospital in Thailand 's Nong Khai province on February 17. Later, samples were sent to Bangkok for testing.

“This morning we received a letter showing initial research from Thai side. That the flu is an H5 virus is clear, but it is not yet clear whether it is H5N1 or not. We cannot yet say whether she was infected with bird flu or not, as more detailed scientific research is needed,” the minister said.

“Today, we sent our doctors to collect a blood sample from the patient, who is now in Thailand , to continue researching the matter. We will also cooperate closely with the Thai side to observe the progress of her health.”

The Director of Vientiane's Health Department, Dr Inlavan Keobounphan, said the girl did not play with chickens. “We are surveying her family members, in particular those live with her in close proximity,” she said.

Health teams have surveyed and interviewed residents in more than 7,800 households in 20 villages of Xaysettha and Sisattanak districts, being areas identified as red and yellow zones respectively, after the avian influenza outbreak was detected on February 16.

Doctors have recorded 150 cases of people who have reported symptoms of illnesses such as colds and flu in the surveyed areas, according to Director of the National Avian Influenza Coordination office, Dr Bounlay Phommasack.

“We continued researching 11 of the 150 cases in more detail, as we suspected that these people might have been infected with bird flu. We found that only three of them were possibly infected with the virus. Finally, just one girl is currently suspected to be infected with avian influenza,” he said.

The government announced the strict implementation of a fivefold strategy to prevent bird flu and its transmission to humans, in cooperation with other countries and international organisations.

“We will continue to be on alert for bird flu outbreaks and will increase the dissemination of information to the public to make sure people understand the issue,” Dr Ponmek said.

Head of the Secretariat of the National Infectious Disease Prevention and Control Committee, who is also Minister and Head of the Government Secretariat, Mr Cheuang Sombounkhane, urged all people, in particular people in Vientiane , not to panic about the issue.

“Our government is setting up strict controls for bird flu, systematically and transparently, by cooperating other countries and international organisations,” he said. “We are confident in the ability of our officials to fulfil our ultimate goal.”

WHO Representative Dr Dong-il Ahn congratulated the Lao government on the efforts made to take action very quickly and transparently.

Laos is surrounded by four countries that have suffered from avian influenza, namely China , Cambodia , Vietnam and Thailand .

“We have to strengthen all our efforts for the prevention of the human cases that may occur if we do not take it seriously,” Dr Dong-il Ahn said.

“We may have to change our methods to include actual surveillance of the hospital system, conducting a hospital health survey. This system has already been tested by the Ministry of Health and the Ministry of Agriculture and Forestry.”

He added that the Lao government has actually been successful in terms of improving their capacity and adopting new health surveillance techniques. He said that, so far, around 174 human cases have been recorded over the last three years, mainly in Indonesia and other Asean countries.

“We will continue to provide technical and financial support to these surveillance activities,” he said.

“I don't feel this one case is very serious, but it is adding to the momentum. We will have to change our tactics for the protection and education of the public.”

Bird flu first broke out in Laos in January, 2004, on 45 farms around Vientiane , and in the provinces of Savannakhet and Champassak. The outbreak was suppressed with the slaughter of 155,000 chickens. The cost of the incident was almost 4 billion kip.

In July 2006, bird flu broke out again in Dong Bang, Nasala and Nontae villages, in Xaythany district in Vientiane , where authorities slaughtered around 20,000 poultry.
 

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Bird Flu Confirmed In Laos

http://www.ecanadanow.com/science/health/2007/02/25/bird-flu-confirmed-in-laos/

Bangkok (eCanadaNow) - Laos’ Public Health Ministry on Monday confirmed that the country’s first suspected human case of avian influenza has been detected, following an outbreak of the virus at a poultry farm on the outskirts of Vientiane earlier this month.

The health ministry identified the suspected case as a 15-year-old girl who had been working on a chicken farm in Srirattana district Vientiane, where an outbreak of H5N1 occurred in late January and was confirmed to be bird flu two weeks ago, said Radio Vientiane in a broadcast monitored in Bangkok.

Foreign Ministry spokesman Yong Chanhthalousy confirmed that authorities have received confirmation from the Mahidol Institute in Bangkok that the girl, who has been moved to Nong Khai Hospital in north-eastern Thailand, has tested positive for H5 but not yet for N1.

“H5 has been confirmed but N1 has not been confirmed according to the result from Thai laboratories, so yesterday we sent a team to Nong Khai to take blood samples to send to Vietnam and Tokyo in collaboration with WHO for a confirmation on this case,” said Yong in a telephone interview with Deutsche Presse-Agentur dpa.

However, Thai avian influenza experts in Bangkok said that a confirmation of H5 in humans amounted to a confirmation of avian influenza in the patient. “In animals there can be H5N2 and H5N3, which is not bird flu, but there is no N variation in human cases, or not yet,” said a Thai health worker, who asked to remain anonymous.

The health of the Lao girl, who was first hospitalized in Vientiane on February 15 and later transferred to Nong Khai Hospital on February 24, was improving, according to Yong.

Yong said Laos had taken all the appropriate measures to prevent the spread of the virus from the infected farm, including culling all poultry in the area and 20 surrounding villages and spraying vehicles entering and leaving the “red zone.”

Laos, which neighbours Thailand, has reported small outbreaks of bird flu in the past, but has yet to confirm a case of a human contracting the virus.

Bird flu has killed 167 people since 2003, when the virus started to ravage Asia’s poultry populations.
 

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Bird flu spreading in Central Russia - emergencies ministry

http://en.rian.ru/russia/20070226/61231399.html

11:47 | 26/ 02/ 2007

MOSCOW, February 26 (RIA Novosti) - Recent cases of avian flu in dead poultry have been registered in the Russian capital and two adjacent regions, the emergencies ministry said Monday.

"Since February 10, dead poultry have been found in Moscow, eight districts of the Moscow Region and a district in the Kaluga Region," the ministry said. "Traces of the deadly H5N1 virus have been confirmed at private farms at 10 locations in these areas."

No cases of humans infected with the virus have been registered so far and emergency measures have been taken to stop the spread of the disease.

"Overall, 2,146 birds have been culled," a ministry's spokesperson said.

According to the World Health Organization, the deadly H5N1 strain of bird flu has infected at least 273 people from 11 countries and claimed 167 human lives since it first appeared in Asia in 2003. It has since spread worldwide, and scientists fear the virus could mutate into a form transmissible between humans, sparking a global pandemic.

Russia recorded its first cases of avian flu in August 2005, but until now outbreaks have occurred only in southern provinces and in Siberia.
 

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No new bird flu cases in Moscow region - official

http://www.interfax.ru/e/B/0/28.html?id_issue=11684089

MOSCOW. Feb 26 (Interfax) - There were no new bird flu cases in the Moscow region last weekend, Federal Veterinarian and Phytosanitary Control Service spokesman Alexei Alexeyenko told Interfax.

"Nothing has changed. The number of farmsteads in the Moscow region where laboratory tests confirm H5N1 deaths remains at nine," he said.

Bird deaths occurred in the Domodedovo, Odintsovo, Podolsk, Naro- Fominsk, Taldom, Volokolamsk, Ramenskoye and Dmitrov regions. Birds sold at the Moscow market (the source of the infection) also appeared to have flu.

The infection is limited, the death toll is insignificant, and bird flu will not spread throughout the Moscow region, he said. The quarantine will last for no less than 21 days.

Birds, that died recently in the Kaluga region, did not have flu, Alexeyev said.
 

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Bird Flu cases found in southeastern Turkey

http://www.kuna.net.kw/Home/Story.aspx?Language=en&DSNO=955891

ISTANBUL, Feb 26 (KUNA) -- Turkish authorities discovered Monday (H5N1) Bird Flu cases in Batman city southeast of Turkey.

Medical official at the Turkish Ministry of Health, Erdal Uzer, revealed that the cases were found in a town near Batman city, indicating that authorities were taking the proper procedures to prevent the disease from spreading.

About 8,000 birds would be exterminated in the process, said the official.

Cases of Bird Flu were discovered last year in several areas in Turkey, especially in poor towns. (end) ta.
 

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Recombinant Human Qinghai H5N1 in Nigeria

http://www.recombinomics.com/News/02250701/H5N1_Nigeria_Recombinant.html

Recombinomics Commentary
February 25, 2007

Recently the HA and NA sequences from H5N1, A/Nigeria/6e/07 from the first human case in Nigeria were released. As expected, the sequences indicated the isolate was the Qinghai strain (Clade 2.2) with expected polymorphisms in HA and NA, including the consensus HA cleavage site GERRRKKR.

However, the HA sequence had a number of regional specific markers indicating it was a recombinant which had acquired polymorphisms in the 2006 isolates in Africa in Europe. Two of the markers were found in isolates from Sudan and western Africa (Nigeria, Ivory Coast, and Burkino Faso) listed here and here. However, other polymorphisms were linked to Egypt and Djibouti, listed here and here. Yet another polymorphism was from Germany and Switzerland, listed here.

This recombining of regional specific markers onto a single gene sequence is easily explained by homologous recombination. Similar acquisitions are seen in the recent Qinghai H5N1 isolates from Egypt, which acquire polymorphisms found in recent isolates from China in Hunan and Shantou. These donor sequences however are on H5N1 isolates that are clearly not the Qinghai (Clade 2.2) isolates, and include a 3 BP deletion found in isolates from Hunan and Egypt.

This polymorphism tracing provides compelling evidence for recombination. Additional examples of such acquisitions are limited by the number of public sequences. Last season H5N1 was reported throughout Europe, the Middle East, and Africa. Many of these samples were sent to the WHO-affiliated lab in Weybridge. A report in May, 2005 indicated over 700 samples from Europe alone were H5N1 positive and a phylogenetic tree representing the HA sequences from approximately 80 of the isolate demonstrated the diversity in the isolates which were clearly the Qinghai strain that was introduced into the region from multiple sources, providing compelling evidence for transportation and transmission by wild birds. Most of those sequences were collected in March, 2006 or earlier, yet one year after collection the sequences are still being hoarded by Weybridge.

This year H5N1 is again being reported in teh region, with outbreaks in Hungary, England, Krasnodar, Moscow, Turkey, and Kuwait, with additional reports from Pakistan, Afghanistan, Egypt, Sudan, Nigeria, and Ivory Coast. Other than the human isolate from Nigeria, only isolates from Egypt have been released, by NAMRU-3 in Cairo.

The recombination of H5N1 in the human isolate in Nigeria is cause for concern. Additional fatal human cases in Nigeria gave inconsistent results, including the mother of the only confirmed case.

The sequences from last season should be released immediately, and additional sequences from the current outbreaks in western Africa, including Nigeria should also be released.
 

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New light shed on flu transmission

http://www.scenta.co.uk/scenta/news.cfm?cit_id=1560485&FAArea1=widgets.content_view_1

The first 3D model of a key influenza protein has shed new light on how bird flu spreads, and could help in combating transmission from birds to humans.

The work, carried out between the European Molecular Biology Laboratory (EMBL), the Institut de Biologie Structurale (IBS) and the Unit of Virus Host Cell Interactions (UVHCI), centred on polymerases (enzymes that carriy out the synthesis of nucleic acids) to more fully understand how the virus spreads.

In the case of H5N1, mutations in the polymerase have contributed to its ability to jump the species barrier from birds to humans.

When infection occurs, the flu virus starts multiplying in the cells of an infected host. The polymerase is a central part of this as it copies the viral genome and directs the production of its proteins.

Interfering with this process could lead to a reduction of or halt virus replication, thereby reducing its spread and the severity of the infection.

According to Darren Hart, one of the contributors to the study: "For many years scientists have tried to understand the flu polymerase and to look for weak points that could be targeted by drugs, but no one could get enough protein to analyse its structure.

"We developed a way to use robots to screen tens of thousands of experimental conditions and discovered a piece of the influenza polymerase that we could work with.

"It is a small part of the entire protein, but it provides interesting insights into how the protein works and how mutations may affect host range."

The team managed to visualise the atomic structure of the protein and uncovered a previously overlooked signal that marks it down from transport to the human nucleus, where it in turn replicates the genetic material of the virus.

The tests identified that the human nuclear transport system importin alpha recognises the signal and shuttles the polymerase into the nucleus.

The team used the high intensity X-ray of the European Synchrotron Radiation Facility to generate a high resolution image of the two proteins interacting.

Results demonstrated that mutations that play a part in the transmission of avian flu were located at or around this interaction, which show that mutations may affect the efficiency of nuclear transport and therefore the ability of the virus to replicate in different species.

The report is published in Nature Structural and Molecular Biology.
 

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Indon Vets Develop Disinfectant Spray That Kills H5N1 Virus

http://www.bernama.com.my/bernama/v3/news.php?id=248667

JAKARTA, Feb 26 (Bernama) -- A team of Indonesian veterinarians has developed a disinfectant spray it claims kills the bird-flu virus on contact.

The team from Airlangga University in Surabaya, East Java, said the disinfectant could be used to spray cages and areas where fowl have died from H5N1, the strain of avian influenza that can be deadly in humans, to prevent it from spreading, the state-run Antara news agency reported.

"Just as we have been fogging to control dengue fever, we expect this new disinfectant to be able to prevent the bird-flu virus from infecting humans," Fedik Abdul Rantam, a professor at the university's veterinary school and the team 's leader, was quoted as saying.

"As soon as there are fowl dead of the virus, we can spray the disinfectant right away," he said.

Indonesia has the world's highest human death toll from bird flu with 64 fatalities, including six this year.

To stop the spread of the virus, the Jakarta city administration has banned backyard poultry farms in residential areas in the capital, which has been followed by nine other provinces.

Most bird-flu victims around the world had direct or indirect contact with sick birds, but scientists said they fear the virus could mutate into a form easily transmissible among humans, sparking a global pandemic that could kill millions.
 

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Two new bird flu sites discovered in Kuwait

http://www.kuna.net.kw/Home/Story.aspx?Language=en&DSNO=956047

KUWAIT, Feb 26 (KUNA) -- Two more bird flu sites were discovered in Kuwait in backyard chicken cages, but local authorities are yet to discover any such cases in chicken and egg farm, the Anti-Bird Flu Joint Committee said Monday.

Following a meeting of the committee, headed by Health Minister Sheikh Ahmad Al-Abdullah Al-Sabah, a statement was issued indicating that the new cases were three turkeys and nine hens raised in backyard cages.

The sites where the dead birds were spotted were "disinfected" and "the dead birds were disposed of in line with international standards" of public safety, the committee said in a statement after being briefed on the issue by the Public Authority for Agriculture and Fisheries.

Furthermore, all surviving poultry in infected sites should also be disposed of, in line with the international safety instructions.

"Blood samples from humans who were in contact with the infected birds were examined. But the results were negative so far," the statement added.

The authority expressed appreciation for the positive public response to the official campaign aimed at monitoring the disease and preventing it from spreading any further.

The committee was also briefed on a recent meeting with owners of poultry and egg farms here to instruct them further on public safety and emergency measures to be taken in case the disease worsens.

The committee praised the cooperation that has been shown on this issue between the Health Ministry and the Authority.

The statement indicated that blood samples from all humans that were near the contaminated birds were secured as a prelude to being tested for the disease.

The Health Ministry has stockpiled preventative and treatment medicines in sufficient quantities, the statement said.

The Joint Committee includes members from the ministry, the authority and the Kuwait Scientific Research Institute as well as the Kuwait Municipality and Ministry of Commerce.

Some cases of bird flu were reported Sunday among falcons. But no other poultry cases were reported until Monday. (end) fs.
 

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Bird flu re-emerges in northern Vietnam

http://www.thanhniennews.com/healthy/?catid=8&newsid=25505

According to head of the provincial animal health department Dong Van Chuc, the department immediately culled the whole flock of 10,500 birds. The infected site was quarantined and sterilized.

The disease has not spread any further, said Chuc.

Bird flu, or the H5N1 virus, which resurged in Vietnam’s Mekong Delta last December, has been contained in the region for over a month.

Vietnam has recorded the second-highest number of H5N1-related human deaths after Indonesia since the virus first hit in 2003. But no human case has occurred in Vietnam since November 2005.

The World Health Organization said a total of 166 people have died from bird flu since 2003.
 

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UPDATE 1-U.S. FDA staff questions Sanofi bird flu vaccine

http://investing.reuters.co.uk/news...6298906_RTRIDST_0_BIRDFLU-SANOFI-UPDATE-1.XML

By Susan Heavey

WASHINGTON, Feb26 (Reuters) - Data on Sanofi-Aventis' (SNY.N: Quote, Profile , Research) (SASY.PA: Quote, Profile , Research) experimental bird flu vaccine shows higher doses worked better, but it is unclear whether those results prove the product's effectiveness, U.S. Food and Drug Administration staff said in documents released on Monday.

The comments came ahead of an FDA advisory panel meeting on Tuesday where experts will discuss whether to recommend approval of the vaccine. If it ultimately wins FDA support, it could become the first U.S.-approved vaccine for the H5N1 influenza virus, which so far affects mostly birds but can sometimes infect humans.

In their memo, FDA staff also said studies of the vaccine, which targets the potentially pandemic H5N1 strain of the influenza virus, showed "no significant safety signals."

While the agency has the final say, it usually follows the advice of its outside advisers.

Sanofi stock was marginally higher at $43.87 per share in late morning trading on the New York Stock Exchange.

GlaxoSmithKline Plc (GSK.L: Quote, Profile , Research) (GSK.N: Quote, Profile , Research) and Novartis AG (NOVN.VX: Quote, Profile , Research) (NVS.N: Quote, Profile , Research) are also developing bird flu vaccines.

Glaxo shares were up 0.28 percent at $57.08 while shares of Novartis were down 1.8 percent at $57.58, also on the NYSE.

The documents memo was posted on the FDA's Web site at http://www.fda.gov/ohrms/dockets/ac/cber07.htm#VaccinesandRelatedBiological
 

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Iran

Bird Flu Warning

http://english.farsnews.com/newstext.php?nn=8505210474

TEHRAN (Fars News Agency)- An Iranian academic center raised the warning status for regional bird flu contamination in northern Iran.


In a statement released on Saturday, Gilan Medical Sciences University demanded the public to observe the rules of hygiene and to take the necessary precautions.

The university has also called on people to refrain from selling and buying of living birds.

It has also demanded the public to avoid direct contact with domestic and wild birds and to inform health authorities of the nearest health center or animal clinics if ever they come across any suspicious case.
 

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Unconfirmed report raises suspicion of Bird Flu virus in Iran

http://armenianow.com/?action=viewA...ng&PHPSESSID=01b8b9727ba99a025708ad461105e339

By Siranouish Gevorgyan and Marianna Grigoryan
ArmeniaNow reporters
A newspaper published in Baku, Azerbaijan has reported that about 2,000 dead birds have been found in a water reservoir in Iran near the Armenian border.

According to “Olaylar” (and republished on www.day.az), analyses taken from the carcasses has been sent to laboratories in Tehran and in Italy to determine whether the fowl was infected by Avian Influenza (Bird Flu).

The specific reservoir was not named in the article. There are two reservoirs on Iranian territory along the Arax River – the Arax-Hydro Unit in Nakichevan and the Horadiz, which borders Nagorno Karabakh. (Iran and Armenia share borders with the Arax.)

Health officials in Yerevan contacted by ArmeniaNow said they had not heard about any such discovery.

“I have talked to my Iranian colleague, and he doesn’t have any information, either,” said Grisha Baghyan, head of the State Veterinary Inspection Department of the Ministry of Agriculture.

Edward Stepanyan, deputy director of the same department told ArmeniaNow that the border with Iran is carefully monitored by Russian soldiers who are on alert for any suspicion of potential health hazards, particularly Bird Flu, and that no information has come from them.

Stepanyan says that, even if the report is true, Armenia has taken all measures – including stocking up on anti-virus vaccines – to resist any outbreak of the virus.

Over the summer, various international agencies, including World Bank, USAID, European Commission and World Food Programme, have provided training, equipment and conducted public awareness campaigns in Armenia.

In January, incidents of Bird Flu were reported in Azerbaijan, Georgia, Iran, and Turkey, near the border with Armenia. While neighbors had outbreaks, Armenian officials assured that no cases of the virus were found here.

Stepanyan said that, due to recent cooperation with international agencies and based on experiences of other countries, Armenia is “even more prepared than we were last year” to combat Bird Flu. The Ministry of Agriculture plans to open a telephone hotline later this month to aid public awareness of the issue.

ArmeniaNow has not yet been able to confirm the Azeri newspaper report.
 

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9 Bird Flu Sites Confirmed

http://www.moscowtimes.ru/stories/2007/02/27/031.html

Authorities on Monday confirmed cases of bird flu at nine locations in the Moscow region, a source in the Agriculture Ministry told Interfax.

The source of the bird flu outbreak has been eliminated, and affected areas remain under quarantine, the source said.

Also Monday, authorities in the Kaluga region confirmed that 17 chickens in the village of Kolodkino had died of bird flu. The village is under quarantine, Interfax reported. (MT)
 

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Egyptian health official denies new bird flu case

http://news.yahoo.com/s/nm/20070226/wl_nm/birdflu_egypt_denial_dc

CAIRO (Reuters) - An Egyptian Health Ministry official denied on Monday a report by the state news agency that a woman from the Nile Delta had tested positive for the deadly bird flu virus.

"It's not true," said Amr Qandil, director of communicable diseases at the ministry. "I do not know where they got this information."

State news agency MENA reported that a 31-year-old housewife from the Nile Delta province of Beheira, Samia Mansour Hashem, had tested positive for the bird flu virus. It said that the woman raised chickens in her home.

She had been taken to hospital in the town of Damanhour but was transferred to Alexandria Fever Hospital when her condition deteriorated, MENA said. Veterinary workers had also been sent to her home to test birds there, the agency said.

World Health Organization officials, who normally confirm human bird flu cases, were not immediately available for comment, nor were doctors at the Alexandria Fever Hospital.

Egypt has the highest number of human bird flu cases outside of Asia. Some 22 people have been confirmed to have tested positive for the disease, and 13 have died.

Most people infected in Egypt had been in contact with live birds kept at home.
Bird flu initially caused panic across the country and did extensive damage to the poultry industry, although the sector has largely recovered.

World Health Organization officials have said a delay in reporting symptoms in Egypt, where many people keep poultry at home, made the virus harder to fight.
 

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Indonesia

Suspected bird flu cases in Padang

http://www.thejakartapost.com/detailnational.asp?fileid=20070227.G08&irec=7

PADANG, West Sumatra: Three suspected bird flu patients have been receiving treatment at M. Djamil Hospital in Padang, West Sumatra, a hospital executive said Monday.

Ira Yanti, head of the hospital's medical services section, said the condition of the three had been improving. Results of laboratory tests from the Directorate General for Disease Control in Jakarta are still pending, which would determine whether the three are infected by the avian flu virus.

Ira said the patients were members of the same family in Padang Gantiang district in Tanahdatar regency.

Three days before they began displaying symptoms several of their chickens died suddenly. Tests conducted by the West Sumatra Husbandry Office confirmed the birds were infected with the virus.

As of last year M. Djamil Hospital has treated 18 suspected bird flu patients. Only two of them tested positive for the virus, with both recovering.

"The two patients were infected in Lampung and Jakarta. They are Minang people who had just returned home to Padang and received medical treatment here," Ira said. -- JP
 

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Laos confirms first human bird flu case, teenage girl remains hospitalized

http://www.iht.com/articles/ap/2007/02/27/asia/AS-GEN-Laos-Bird-Flu.php

HANOI, Vietnam: Health officials in Laos on Tuesday confirmed the country's first human bird flu case, according to the World Health Organization.

A 15-year-old girl living outside the capital of Vientiane fell ill Feb. 10 with flu-like symptoms after the H5N1 virus was confirmed in poultry days earlier in the same area, according to a joint statement by the Lao Ministry of Health and the WHO.

The girl was hospitalized in Vientiane and later transferred to Thailand, where she is in stable condition, it said. Lab results came back positive for the virus on Saturday.
 

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Kuwait confirms 12 new bird flu cases

http://today.reuters.com/news/artic...BIRDFLU.xml&WTmodLoc=NewsHome-C3-healthNews-2

KUWAIT (Reuters) - Kuwait confirmed on Tuesday 12 cases of the deadly H5N1 strain of bird flu in turkeys and chicken on Tuesday, but said the birds did not belong to poultry farms.

The ministry confirmed on Monday 20 cases in falcons of the same strain at a zoo and a farm in the south of the country, the first in two years.

In the latest development, a health ministry official confirmed a newspaper report that three turkeys and nine chicken were infected and said the ministry was testing people who came in contact with the birds.

The cases were found among "domestic backyard caged birds, not on poultry producing farms," Ahmed al-Shatti told Reuters.

"About 100 handlers and families of owners of infected birds have been tested and the results were negative. We are continuing the tests," he said

The Gulf Arab state has banned the import of live birds after the outbreaks. It reported a case of the deadly bird flu in a flamingo in 2005.
 

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Sanofi Bird-Flu Shot's Benefit Isn't Clear, FDA Says (Update3)

http://www.bloomberg.com/apps/news?pid=20601085&sid=aBmU9f3RLn2w&refer=europe

By Angela Zimm

Feb. 26 (Bloomberg) -- Sanofi-Aventis SA's bird-flu shot triggered an immune response in less than half of the patients tested, raising questions about whether the shot could help prevent a pandemic.

The effectiveness of the vaccine is ``not clear,'' staff of the U.S. Food and Drug Administration said in a review posted today on the agency's Web site. A panel of FDA advisers will meet tomorrow to decide whether to recommend approval of the vaccine.

Sanofi, the largest supplier of flu vaccines to the U.S., is seeking clearance for the first shot to protect against the H5N1 virus, a strain widespread in birds that scientists say could mutate into a form that can spread from human to human. A researcher acknowledged the results aren't definitive.

``It's not clear what constitutes an effective vaccine and how to assess that,'' John Treanor, professor of medicine at the University of Rochester Medical Center and a researcher on clinical trials of the vaccine, said in an interview. ``That's the giant 800-pound gorilla hanging over all efforts to develop a vaccine against H5N1. We're using levels of antibodies as a surrogate marker for being protected.''

The U.S. government, the only customer for Sanofi's bird-flu shot, stockpiles the vaccine and already has awarded the Paris- based drugmaker $372 million in contracts for the product. Sanofi doesn't plan to market the vaccine to the public.

Immune Response

Previous studies suggest that raising immune antibodies to certain levels is associated with a 50 percent protection against flu, although it's not clear that the response proves the vaccine's effectiveness, the FDA staff said.

``No studies have been designed to actually measure protection since there is no widespread circulation of disease,'' Sanofi spokesman Len Lavenda said in an e-mail. ``This is true of all pandemic vaccine trials.''

Other companies working on pandemic flu vaccines include GlaxoSmithKline Plc and Novartis SA.

Sanofi's vaccine, given in two doses a month apart, stimulated an immune response in 45 percent of study participants, according to the FDA documents. In a study published last year in the New England Journal of Medicine, the vaccine triggered a protective immune response in 53 percent of participants.

The discrepancy reflected ``different methods of interpreting'' the goals of the study, Lavenda said. ``A more detailed explanation of these recalculations will be presented tomorrow.''

Scientists have been monitoring outbreaks of the H5N1 virus that has struck birds and humans in Asia and elsewhere, urging companies and researchers to speed development of a vaccine against the lethal illness. At least 167 of the 274 people known to be infected with bird flu since 2003 have died, according to the World Health Organization. Most of the cases of avian flu infection were passed from birds to humans. The virus hasn't been detected in the U.S.

FDA reviewers questioned Sanofi's plan for monitoring safety of the vaccine after approval, saying that the company sought changes in FDA reporting requirements.

``In the event of a pandemic and a subsequent mass vaccination program, it seems imperative the U.S. be well prepared to detect a problem that occurred once before,'' the reviewers said. They referred to cases of a paralyzing neurologic condition called Guillain Barre Syndrome during a mass vaccination effort against swine influenza in the U.S. in the 1976-1977 flu season.
 

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Valid concerns over bird flu: UAE daily

http://www.upi.com/Arabia2000/view.php?StoryID=20070227-630140-7273-r

Abu Dhabi, Feb. 27, 2007 (WAM) -- A major UAE English daily today commented on the outbreak of bird flu in Kuwait which is beginning to cause panic in the region..

Commenting editorially in its issue of today, the Dubai-based "Gulf News" said: "Bird flu is making the headlines again, this time with an outbreak in Kuwait. It may also be in Iraq but it is obviously difficult to prove or monitor. With each passing week it seems more areas of the globe succumb. While health officials are right to say that this is a cause for concern they are also right to warn about the dangers of mass panic..

"Less than 200 people have died worldwide from bird flu since 2003. Other diseases pose a far greater risk to humanity. Malaria for instance or the scourge of HIV/Aids. The common cold has claimed more lives worldwide and while bird flu has a high fatality rate, currently about 60 per cent, it has not mutated into symptoms that are easily transmitted among humans.

"Practical measures, such as making sure that all poultry products are cooked properly, washing hands before preparing meals and not coming into contact with wild birds, have all been successful in curtailing its spread. But the World Health Organisation expects a flu pandemic to break out at any moment and there is a legitimate concern that any pandemic could take on the characteristics of bird flu. If this did occur, the impact would be severe with air travel facing restrictions as would events involving large crowds. But we are not at that stage.

"With spring approaching in the northern hemisphere the migratory patterns of birds will change which in turn could see a rise in the number of birds contracting the disease in Europe, north Africa and countries near the Mediterranean. Local solutions are the best answer to global fears. What happens in your home and community can have an international impact. Adhering to simple, common-sense rules on hygiene and cooking will cut down the risk of bird flu spreading." WAM/SA 09 28 CCCCQQ
 

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Update on investigation of workers involved in the Holton avian flu outbreak

http://www.news-medical.net/?id=22230

Britain's Health Protection Agency (HPA) has now completed the first stage of the public health follow up in relation to the outbreak of avian flu on a poultry farm in Holton, Suffolk.

The Agency alongside local NHS public health colleagues, the Department for the Environment, Food and Rural Affairs (Defra) and Bernard Matthews has offered antiviral drugs to 480 people and 310 of those have so far received seasonal flu vaccination. The local Health Protection Unit continues to monitor the situation locally working together with Defra and Bernard Matthews.

As a precautionary measure only a small number of workers who are involved in the cleaning and decontamination process are continuing to take antiviral medications.

The Agency has carried out testing on a total of six people who developed flu like symptoms. Three of these people met the Agency's criteria for testing and three others were tested as a precautionary measure. All six patients tested negative for avian flu, and received appropriate medical care.

Dr Jonathan Van Tam , a flu expert at the Agency, said : "The risk of any workers testing positive for avian flu has been and remains very low as they have followed all the necessary precautions in terms of protective clothing and hygiene measures, and have been offered antiviral drugs."

The Agency also concluded that the risk to food processing workers and other personnel working in around the food processing plant as being very low and as a result they didn't require any antiviral treatment.

H5N1 avian flu remains largely a disease of birds. The virus does not transmit easily to humans, as evidenced by the 270 or so confirmed infections worldwide to date, versus the millions of people exposed to poultry everyday in SE Asia . Almost all human H5N1 infections so far have been associated with close contact with dead or dying poultry and in all human cases there has been no evidence of efficient human to human transmission.
 

JPD

Inactive
WHO: "30% of world population is supposed to contract the virus in case Bird flu pandemic"

http://www.today.az/news/society/37103.html

27 February 2007 [14:34] - Today.Az
Three-day symposium on the theme "Communication during emergencies situations on public health and relations with mass media" organized by UNISEF started in Baku.

UNICEF officer in Azerbaijan Haana Singer said that this event is one of the six seminars that will be held in CIS states, APA reports.

Mentioning that three children died of bird flu in Azerbaijan, she said they contracted H5N1 strain of virus in their yards.

"If this disease transmits from human to human, millions of people can die. Warning and effective inquiry system should be established to prevent this," she said.

Head epidemiologist Ibadulla Agayev said that out of eight bird flu infected men in Azerbaijan 5 died.

"Measures are being taken to prevent spread of bird flu virus in the country. President Ilham Aliyev controls the situation," he said.

World Health Organization expert Roberta Andragnetti warned that the most dangerous stage of the disease is when it transmits from human to human.

"30% of the world population is supposed to die of H5N1 in case of bird flu pandemic. The worst is that the disease can be repeated within 2-3 years. In case of pandemic vaccine can be prepared only after six months. Therefore it will be difficult to fight against the disease in the first 6 months," the expert said.

The symposium will end on March 1.
 

JPD

Inactive
Thousands of birds vaccinated in Jalalabad

http://www.gulf-times.com/site/topi...=135238&version=1&template_id=41&parent_id=23

KABUL: Around 4,000 chickens a day are being vaccinated in Afghanistan after outbreaks of the H5N1 virus but the slaughtering of birds is being slowed by local resistance, officials said yesterday.

Teams started working in the eastern city of Jalalabad and in Kunar province at the weekend after confirmed cases of the virus, which has killed 167 people worldwide since 2003.

Suspected poultry was being quarantined and contaminated areas were being disinfected, UN spokesman Adrian Edwards said.

"At this time the situation is under control," he said.

The slaughtering of birds was facing resistance among local people, agriculture department director Aziz Usmani said.

"People are not always willing to allow their birds to be culled," he said.
Officials say Afghanistan is at high risk of H5N1 spreading to humans because most families keep birds at home.

Scientists fear a global pandemic if the virus mutates and becomes easily transmissible between humans. - AFP
 

connie

Veteran Member
In the last great flu epidemic, our soldiers took the flu to Europe.

In this epidemic, our soldiers will bring in home from Afghanistan.

I don't think I've ever heard of a flu epidemic during the summer months in my lifetime. Is it possible?
 

JPD

Inactive
Bird Flu Spreads in Asia, Middle East as First Infections Found

http://www.bloomberg.com/apps/news?pid=20601087&sid=a02wk0HA8hgQ&refer=worldwide

By Jason Gale and Nguyen Dieu Tu Uyen

Feb. 27 (Bloomberg) -- Bird flu spread in Asia and the Middle East as Laos reported its first human case of the virus and the virus was confirmed for the first time in Kuwait.

The lethal H5N1 strain of avian influenza infected a 15- year-old girl in Laos, the World Health Organization and the health ministry said in the e-mailed statement. The teenager, who is in the hospital, is from a suburb of the capital, Vientiane, where an outbreak of the H5N1 virus in poultry was confirmed on Feb. 7, the agencies said.

Kuwait reported its first avian outbreaks of the H5N1 virus, the World Organization for Animal Health said today. In the past three months, fresh poultry outbreaks were also reported in Thailand, Japan, South Korea, Hong Kong, Pakistan, Afghanistan, Turkey, Russia, the U.K., Hungary, Nigeria and Egypt. Diseased fowl increase the risk of human infection and provide chances for H5N1 to mutate into a deadly pandemic form.

``The number of outbreaks around the globe and the number of human cases are certainly not going down,'' Ron Fouchier, a virologist at the Erasmus University in Rotterdam, said in a telephone interview today. ``The problem is still there and the longer the problem is there, the bigger it may get.''

At least 167 of the 275 people known to be infected with bird flu since 2003 have died, according to the Geneva-based WHO. This year, disease trackers have reported 12 cases, including nine deaths. Millions could die if H5N1 becomes as contagious as seasonal flu, sparking a worldwide outbreak.

Human Cases

``The number of humans cases is still rising rapidly,'' Fouchier said. ``It doesn't seem to slow down. Every human case is an additional opportunity for the virus to adapt or to mix genetically with human viruses. As long as this is continuing, the chances are getting bigger'' for a global outbreak.

Avian flu killed 43 birds in Kuwait, the Middle Eastern country's first reported outbreak of the lethal virus, the World Organization for Animal Health said. The H5N1 strain of avian influenza was confirmed to have caused six outbreaks in the country since mid-February, the Paris-based agency said in an e- mailed statement.

The outbreaks occurred at the Kuwait Zoo in Al Omaria and in the region of Wafra, the agency said. More than 2,600 birds were destroyed to control the virus, which threatened to infect about 3,651 birds.

Kuwait reported an initial outbreak of highly pathogenic avian influenza in November 2005.

Vietnam Outbreak

Vietnam, which borders Laos, this month detected its first outbreak in Hai Duong since December 2005. Bird flu killed about 6,000 chickens in the northern province, where infections began about two weeks ago on a farm, said Hoang Van Nam, deputy head of Vietnam's Animal Health Department. The province borders the capital, Hanoi, to the north.

The latest infected farm raised about 10,500 fowl, Nam said in a telephone interview from Hanoi today. ``It is a private farm and the birds were not vaccinated,'' he said, adding that the farm's owner and local animal health officials failed to follow animal-health guidelines.

Vietnam has recorded at least 2,368 outbreaks of the H5N1 strain of avian influenza during the past four years, about 1,200 more than any other country, according to the World Organization for Animal Health. About 50 outbreaks were reported this year, partly because farmers ignored regulations requiring poultry to be vaccinated against the disease.

The Southeast Asian nation has culled about 112,000 poultry since December to contain outbreaks across eight provinces in the southern Mekong Delta region.

Vietnam has reported 93 human H5N1 cases, more than any other country. Of those, 42 were fatal. The country's last human case was reported in November 2005.

``I have not seen any hard data to support'' the suggestion that the virus is becoming better adapted to humans, Fouchier said. ``People are looking into whether there are particular traits that are more frequently seen in humans than in poultry.''
 

JPD

Inactive
Bird-flu shot better than nothing, experts says

Vaccine doesn't work very well, but FDA advisers urge approval anyway

http://www.msnbc.msn.com/id/17363375/

Updated: 13 minutes ago

WASHINGTON - Federal health advisers recommended Tuesday that the government approve the first bird flu vaccine as a stopgap measure, despite evidence it wouldn’t protect most people.

In separate votes, the outside panel said the vaccine was both safe and effective. A vaccine must meet both standards to win FDA approval. The votes came after Food and Drug Administration officials said the Sanofi Aventis SA vaccine still could play an important role in protecting against the increased likelihood of a pandemic, despite its limited effectiveness.

The FDA isn’t required to follow the advice of its advisory committees, but usually does. The vaccine is the first against the H5N1 influenza strain to seek government approval.

The vaccine already is being stockpiled, even without FDA approval, for eventual interim use to protect emergency workers and others in a pandemic. It would be used until better vaccines could be developed. Though not required, FDA approval would state the agency’s opinion on the vaccine’s safety and effectiveness, said Dr. Jesse Goodman, FDA’s chief of biologic products.

In a clinical trial, the two-shot series appears to provide protection to just 45 percent of adults who received the highest dose. An earlier, interim analysis of the same study had suggested it prompted a protective immune response in 54 percent of patients, when measured 28 days after getting the second of two shots. The FDA said it would like to see a response in at least 70 percent of those vaccinated against bird flu.

“The more antibodies, the better. But even at lower levels, there is a possibility of protection,” Goodman told reporters on the sidelines of the meeting.

The government plans to buy and stockpile enough bird flu vaccine for 20 million people, including emergency and health care workers. The Sanofi vaccine wouldn’t be sold commercially.
 
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