12/07 H5N1 | The Planet Prepares for Pandemic = A Billion Could Die

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<B><font size=+1 color=green><center>Planet Readies For Avian Flu: A Billion Die</font>

by J. Grant Swank, Jr.
Dec 7, 2005
<A href="http://www.postchronicle.com/news/health/article_2121714.shtml">PostChronicle.com</a></center>

"We must remain on the offensive against new threats to public health, such as the Avian influenza," US President George W. Bush said in his speech to world leaders at the United Nations Summit in New York. "If left unchallenged, the virus could become the first pandemic of the 21st century." </b>
"If we had a significant worldwide epidemic of this particular avian flu, the H5N1 virus, and it hit the United States and the world, because it would be everywhere at once, I think we would see outcomes that would be virtually impossible to imagine," warns Dr. Irwin Redlener, director of the National Center for Disaster Preparedness at Columbia University's Mailman School of Public Health.

Avian flu could cause a billion humans to die globally, according to ABC News. That is why the Bush administration set in motion stockpiling $100 million worth of medicines. However, the vaccine is still in the experimental stage.

"Right now in human beings, it kills 55 percent of the people it infects," says Laurie Garrett, a senior fellow on global health policy at the Council on Foreign Relations. "That makes it the most lethal flu we know of that has ever been on planet Earth affecting human beings."

British officials are now spying out extra morgue square footage to those who would die because of the H5N1 virus. This virus type is brand new to the human race.

The Foreign Affairs publication looks upon this threat as "the coming global epidemic, a pandemic."

Mr. Bush highlighted his personal concern. He cautioned that he did not mean to be overly alarming; but the message given was that America may have an extremely serious problem in the near future — a health problem that could get way out of control.

It started in Asia. Birds like geese, swans and ducks are the culprits. The birds die of a pneumonia. Their lungs are found to be filled with fluid and blood, according to veterinarian for the Wildlife Conservation Society, William Karesh.

The disease goes from wild birds, then to chickens, then to people. "We start at a market somewhere in Guangdong Province in China. And it's packed with cages, and you'll have chickens, and you'll have ducks. You might have some other animals -- cats, dogs, turtles, snakes -- and they're all stacked in cages, and they're all spreading their germs to each other," Karesh explains.

That means that officials must see through the destruction of scores of chickens — thousands at a time. The chance is that the disease can be halted before it reaches mortals. The next stage, after going from lower animals to humans, is human to human.

What concerns government officials worldwide is that many do not understand the magnitude of the problem. Newscasters are reluctant to hammer away constantly on the issue. Even politicians do not want to appear extremely panicky about avian flu. And therefore, nations go on their ways as if all is normal, no threat in sight, while huge populations remain uneducated about what could happen this winter.

Add to this the fact that the medicines are not equipped at present to combat the pandemic. Widespread disease occurrences would be practically impossible to ward off. That would mean that alarming numbers of humans would die without the hoped-for vaccine.

Scientists are working night and day at present in search of virus solutions before the plague hits.

The disease strikes with a cold-type "runny nose." Then there is the sore throat. The lungs are attacked next as that tissue suffers from an extreme pneumonia.

Thus far, infections have come from birds. But once the virus leaps from birds to human to human, then the pandemic sets loose. That would over-ditto the Spanish flu outbreak in 1918.

The avian flu could travel around the planet in a very short time. That is due to international air travel.

People would carry the virus on their hands. Therefore, shaking hands could spread the disease. Door handles and so forth could carry the virus. Whatever is touched could be contaminated.

Such widespread sickness could force blocking off entire geographies so that persons, quarantined, could not go out while others could not go in. Airports, interstates, subways, schools, shopping malls could end up blocked off to entrancing and exiting. Persons could be corralled with strangers who could be disease carriers.

The frightening prospects are numberless: no place to bury the dead. No one to bury them. Not enough caskets. No persons to provide decent burial rites. Orphans. Elderly struck down with no medical assistance. Hospitals shut down or quarantined.

Further, when the avian flu first hits, persons may think it to be the "old-fashioned flu." Therefore, it could spread quickly with persons not realizing the enormity of the danger. As a major killer disease, it would be subtle, indirect and especially cunning at its entry levels.

US Health and Human Services Secretary Michael Leavitt says: "We would do all we could to quarantine. It's not a happy thought. It's something that keeps the president of the United States awake. It keeps me awake." Leavitt says that he wishes there were more time left to perfect a solution.

ABC News' "Primetime" broadcasts that a couple hundred thousand in the United States could be killed by the avian flu in "a few months." Even that number is regarded as low.

Everyone will be asking for the vaccine. But it won't be available. When the vaccine finally is up and running, the supply will not be sufficient.

Tamiflu by Roche pharmaceutical firm in Switzerland is on to a vaccine. It's been marketed for flu. It may work against H5N1. Therefore, every aware nation has been requesting Tamiflu in stockpiles. Only the rich countries, however, can get it. Even then, the supply is not up to what would be the demand.

"Faced with worldwide demand, the Roche company, which produces Tamiflu, has organized a first-come, first-served waiting list. The United States is nowhere near the top," ABC News reports.

But a mutant virus may not be warded off by present vaccines. Therefore, the world would not have a preventative for avian flu when the pandemic strikes. Tamiflu would, in other words, "not fill the bill."

If persons think the hurricane disasters of Katrina and Rita were devastating, such would prove to be pigmy-sized in comparison to a pandemic of avian flu.

"A lot of people don't realize that for this avian flu virus, there will be very little effective therapy available early on," said US Congressman Bill Frist.
 
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<B><font size=+1 color=red><center>Efficient Human to Human H5N1 Transmission in Indonesia</font>

<A href="http://www.recombinomics.com/News/12060501/H2H_H5N1_Efficient_Indonesia.html">Recombinomics Commentary</a>
December 6, 2005</center>

LEAVITT: Yes, millions of people. This is a very serious, world-changing event if it occurs. </b>

Now, there's no certainty that it will occur as the H5N1 virus, but there is a high degree of probability that some pandemic will occur at some point, and we need to be better prepared than we are today.

The above comments on the effects of efficient human-to-human transmission of avian influenza with a case fatality rate of 2-3% accurately predicts some of the consequences, but fails to acknowledge the fact that H5N1 is clearly gaining in efficiency for human-to-human transmission. This increased efficiency is being seen in Vietnam, Thailand, and China, but the clearest picture is emerging in Indonesia, as the number of official WHO confirmed cases continues to rise.

WHO's list of confirmed cases in Indonesia recently rose to 12 with the confirmation of H5N1 in a 16 year old boy. However, the WHO report acknowledges that two brothers of the latest case recently died with bird flu symptoms, but samples for testing were not collected, so the two siblings were not included in the WHO totals. The exclusion due to lack of samples, or inappropriately collected samples, is similar to the first fatalities reported in Indonesia over the summer.

That cluster included 3 fatalities, but again only one of the three is in the list of WHO confirmed cases. The index case, an 8 year-old girl, was admitted, but samples were not collected. He admission was followed by her 1 year-old sister, but again samples were not collected. Samples were collected when the father of the index case was admitted. He tested positive for H5N1 and subsequently became Indonesia's first confirmed H5N1 fatality. Two serum samples were collected from the index case and both were strongly positive for H5N1 antibodies as determined by WHO reference labs in Hong Kong and Atlanta. However, since the samples were collected just 3 days apart, the increased titer in the second collection was not four fold higher than the earlier collection, so the case was excluded from the list of confirmed cases. The 1 year old was also excluded because the proper samples were not collected.

Thus, in the first and most recent cluster there were five H5N1 fatalities, but only one of the five fatalities is on the confirmed list from WHO, which today has 13 cases including 8 fatalities.

The collection procedure plays are large role in the creation of lab confirmed cases. Indonesia, like most countries in Asia collects samples for testing at an infectious diseases hospital. Cases initially go to primary care facilities were samples are not collected for H5N1 testing. By the time the patient is transferred to the infectious disease hospital, the H5N1 has been cleared from the nose and throat, so the swabs are collected too late. Similarly, antibody levels peak at around 30 days post symptoms, so serum collections at 1-3 weeks are too early for antibody collection. Instead the samples are too late for PCR but too early for antibody. The samples are however "Goldilocks" collections which are just right for false negatives.

When a patient does test positive, relatives are tested and this has led to several positives because the samples are collected when the patient first begins to develop symptoms. In many instances, these cases are mild. This was seen in the nephew of the second confirmed case in Indonesia. He had mild symptoms, but a throat swab was collected because is aunt was H5N1 positive. The nephew was tested prior to hospitalization and he subsequently had a fever for 3 days, recovered, and returned to school. This mild case was detected because his aunt was positive. If there was not familial connection, he would have just had a case of the flu that was not identified as being caused by H5N1.

The same situation developed in a 4 year old who had two older siblings hospitalized. The 4 year old was tested when he just had a sore throat and he too was H5N1 positive. The case was mild and the younger brother was discharged. One of the older siblings was positive for H5N1 while the other was negative, but again because of untimely sample collection. Both older brothers recovered.

Thus, collection samples at an nearly stage, when H5N1 is still present in the nose and throat, leads to lab confirmation of H5N1 cases. However. Most mild cases are missed because of Goldilocks testing.

The effects of these policies can be seen in the official cases. Of the 13 confirmed cases, 8 are from familial clusters. Of the five cases not linked to clusters, all five have died because the detection of H5N1 in nose or throat swabs signaled a massive infection where sufficient H5N1 remained in the nose and throat to produce a positive result. Of the 8 confirmed cases in family clusters, only 3 were fatal because many of the positive cases were mild and detected because testing was shortly after onset of symptoms.

In addition to the 8 confirmed cases, 5 other family members were excluded because of improper samples. Thus, of the 13 confirmed and 5 excluded cases, 13 or over 72% of these cases were in familial clusters.

In contrast, only about 1/3 of the cases in southeast Asia were from familial clusters through the spring of this year. This dramatic increase in cases from clusters shows that H5N1 is being more efficiently transmitted and this efficiency can also be seen in recent cases from China, Thailand, and Vietnam.

Thus, suggestions that the next pandemic may not involve H5N1 or that the pandemic is years away, fails to address the dramatic increase in efficiency of human-to-human transmission of H5n1, especially in milder cases such as those in Indonesia.
 
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<B><font size=+1 color=red><center>WHO: More Urgency Needed To Create Bird Flu Vaccine</font>

China Reports 4th Human Bird Flu Case
POSTED: 6:39 am PST December 7, 2005
<A href="http://www.foxreno.com/health/5483088/detail.html">foxreno.com</a></center>

BEIJING -- The World Health Organization wants governments to invest more in developing a vaccine to protect people from bird flu.</b>

The push for a vaccine comes as China confirms its fourth human case of the disease.

The Chinese government said a 10-year-old girl has tested positive for the deadly H5N1 virus. The Xinhua News Agency said the girl has undergone emergency treatment after being sick with a fever and pneumonia since last month.

China's official news agency said people who have had close contact with the girl are under medical observation, but so far no one has shown any symptoms of bird flu.

Two farmers in eastern China died of the disease last month after coming in contact with sick poultry. A 9-year-old boy in a central province also fell ill, but has recovered.

The WHO said China needs to do a better job of educating the public on how to spot bird flu if the disease is to be contained.

Julie Hall, an infectious disease expert at the WHO office in Beijing, said there's still an issue of public awareness of what to look for when chickens get sick. She said early reporting is key and farmers need to have adequate compensation as an incentive.

The virulent strain of bird flu has killed at least 68 people in Asia since 2003. Experts have warned that it could mutate into a form easily passed between people and spark a pandemic that could kill millions around the world.

Meanwhile, Vietnam has banned pharmacies from selling the anti-bird flu drug Tamiflu, saying improper use could cause the virus to develop resistance to the medicine, officials said Wednesday.

Residents afraid of contracting bird flu have rushed to buy the drug, which is sold over-the-counter like all medicines in Vietnam.

But the Pharmaceutical Administration Department, under the Ministry of Health, has instructed provincial health departments and hospitals not to sell Tamiflu.
 
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<B><font size=+1 color=purple><center>Possible human transmission of bird flu investigated</font>

By Kate Walker
Dec 7, 2005, 1:03 GMT
<A href="http://news.monstersandcritics.com/health/article_1067075.php/Flu_Roundup_Possible_human_transmission_of_bird_flu_investigated">monstersandcritcs.com</a></center>

WASHINGTON, DC, United States (UPI) -- There has been further debate concerning the possible instances of human-to-human avian-influenza transmission suspected by some scientists in Thailand and Indonesia.</b>

The suspected cases of human-to-human transmission are currently being examined by international health authorities, and there has not yet been any confirmation that the disease can be contracted from anything other than infected birds and their mucus and feces.

It is possible that the cases currently under review, that of two young men in Thailand, and three members of the same family and a nurse in Vietnam, do not represent the human transmissible pandemic much forecast in the media, but instead are an interim step in the infectious process.

Scientists and health experts have long discussed the possibility that H5N1 may trade some of its virulence for increased transmission, leading to a dramatic increase in the number of cases reported, but an equal decline in the disease`s mortality rates, currently in the vicinity of 50 percent.

Dr. Charoen Chuchottaworn, the Thai avian-flu expert whose fears of human-to-human transmission were reported by United Press International Dec. 2, believed that the cases he observed where the infected reported only mild influenza symptoms yet tested positive for H5N1 were a likely example of the virus exchanging pathogenicity for ease of infection and theorized that the cases he had seen may represent only 'the tip of an iceberg.'

A report originally published by the Cox News Service said, 'Planners believe that some person-to-person transmission has occurred but say limited health care resources in Asia make it difficult to detect clustered cases.'

However, Dr. Scott Dowell of the Centers for Disease Control and Prevention, said, 'It is always difficult to be sure if you have a couple of cases in a family, because generally speaking, members of a family have been exposed to the family`s chickens as well as to each other.'

Although it is presently impossible to ascertain whether any form of human-to-human transmission has ever occurred, either of the high- or low-pathogenic variety, it is human-to-human transmission that health experts most fear, and the results of the investigations currently under way by international health authorities are eagerly awaited.

Meanwhile:

-- China confirmed its fourth human case of avian-influenza infection Tuesday.

A 10-year-old girl from Guangxi, in the south of the country, has been suffering from fever and flu-like symptoms since Nov. 23, although tests only confirmed the presence of H5N1 this week.

The girl, who is in critical condition, was exposed to infected birds before contracting the infection and is not thought to be an example of the possible human-to-human transmission suspected by some scientists in Southeast Asia.

None of her friends or family members has exhibited signs of infection, giving further credence to the belief that she was contaminated by sick poultry.

The Chinese government responded to the confirmation of infection by sending specialized infection-control teams to Ziyuan county, where the girl lives.

-- In response to the outbreaks confirmed over the weekend, and which locals claim have been reported without action since September, the Ukrainian government Tuesday declared a state of emergency in the autonomous region of Crimea.

Mass poultry vaccinations are currently in progress, and Ukraine has banned imports of poultry from the area covered by the state of emergency.
 
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<B><center>12/06/2005 / 20:59

<A href="http://www.ukranews.com/cgi-bin/openarticle.pl?lang=eng&id=692233&lenta=po">Ukrainian.News.com</a>
<font size=+1 color=red>Another Bird Flu Hotbed Found In Crimea</font></center>

One more hotbed of avian flu has been discovered in the village of Chornozemne of the Sovietskyi district in Crimea.

Ukrainian News has learned this from Deputy Chairman of the State Department of Veterinary Medicine Mykola Patsiuk.</b>

Eight infected birds have been found in the village, Patsiuk said.

"In two farmstead of the Sovietskyi district, the village of Chornozemne, eight infected birds - five hens and three ducks - have been found today (December 6)," he said.

Patsiuk noted that birds were sent to the Republican Crimean Veterinary Hospital for confirmation of the diagnosis.

Patsiuk also said that the staff center is receiving reports on infected birds from other populated areas of the quarantine zone. However, the information is yet to be checked.

Earlier, hotbeds of bird flu were discovered in Nekrasovka, Sovietskyi district, in Zavit-Leninskyi and Pushkine, Dzhankoi district, Izobilne and Omelianivka, Nyzhniohirsk district.

As Ukrainian News reported, on Tuesday, the Verkhovna Rada approved President Viktor Yuschenko's decree that introduced a state of emergency in the Crimean population centers where the bird-flu virus has been found in birds.
 
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<B><font size=+1 color=purple><center>Bird flue could "hibernate", reemerge later - official</font>

17:13 | 07/ 12/ 2005
<A href="http://en.rian.ru/world/20051207/42360850.html">RIA Novosti</a></center>

MOSCOW, December 7 (RIA Novosti) - The bird flu virus could "hibernate" in Ukraine's autonomy of the Crimea this winter and then reemerge in spring, the head of the Federal Service for the Oversight of Consumer Protection and Welfare said Wednesday.</b>

"It is not good that the weather in the Crimea is warm and migrating birds will stay there to spend the winter," Gennady Onishchenko said. "The situation will develop further."

He said a group of specialists set off to Ukraine to conduct tests on dead birds to see whether the virus strain in the Crimea is identical to the registered strain in Russia.

Ukraine's Emergency Situations Ministry said last week that a highly pathogenic strain of the bird flu virus had been discovered in three regions of the autonomy.
 
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<B><font size=+1 color=blue><center>WHO head meets Bush to discuss possible bird flu pandemic</font>

<A href="http://english.yna.co.kr/Engnews/20051207/460100000020051207114202E7.html">YONLAP News.com</a></center>

GENEVA, Dec. 6 (Yonhap) -- Lee Jong-wook, director-general of the World Health Organization (WHO), met with U.S. President George W. Bush in the White House to discuss ways of preventing an avian influenza pandemic, the world body said Tuesday.</b>

Bush invited Lee to his office Tuesday morning (local time) and thanked him for his efforts to head off a possible pandemic and eradicate other diseases
 
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<B><font size=+1 color=blue><center>White House to hold flu response exercise</font>

December 7 2005
<A href="http://www.ledger-enquirer.com/mld/ledgerenquirer/news/politics/13350174.htm">Associated Press-AP Wire</a></center>

WASHINGTON - The White House is hosting a top-level exercise this weekend to test the federal government's plans for responding to any flu pandemic outbreak in the United States.</b>

The four-hour "tabletop exercise" is being held Saturday at the White House and will be attended by Cabinet secretaries and other top government officials, but not the president, White House press secretary Scott McClellan said Wednesday.

"We have done much to plan for a pandemic," McClellan said. "But planning alone is not enough. Plans must be tested and improved upon."

McClellan did not say whether state officials also would participate, or give any other details of how the exercise would be conducted.

Fears of a pandemic have increased in recent months as a virus infecting millions of birds has spread throughout Asia. While the virus has not yet spread from person to person, officials fear that it could eventually mutate and become as contagious as the annual flu.

Human-to-human transmission of the virus would be particularly deadly because humans have no immunity to the virus. So far, the virus has killed about half of the 120 people who have contracted it as a result of close contact with poultry.

The administration is working under the assumption that as many as 90 million Americans would become sick during a global flu pandemic. A moderate pandemic would kill about 209,000. A severe one, such as the one that occurred in 1918, would kill about 1.9 million people.
 

Onebyone

Inactive
The administration is working under the assumption that as many as 90 million Americans would become sick during a global flu pandemic. A moderate pandemic would kill about 209,000. A severe one, such as the one that occurred in 1918, would kill about 1.9 million people.

That doesn't make sense. Above they say the flu is killing half of all the people who get it then that would mean if 90 million people get it then 45 million people would die not 1.9 million people.
 

Rex Jackson

Has No Life - Lives on TB
Just cant help to think this is all BS at times. I hear all about this 'wiping the planet' yet its just laying around. At times it seems to be just a smoke screen for something else.
 

Hoosier Daddy

Membership Revoked
Rex Jackson said:
Just cant help to think this is all BS at times. I hear all about this 'wiping the planet' yet its just laying around. At times it seems to be just a smoke screen for something else.


Perhaps another Reichstag Fire?
Maybe this time to implement the Emergency Health Powers Act?
Possibly with the goal of disarming those in "quarantine".

I have zero trust or faith in those in charge of our government
 

JohnGaltfla

#NeverTrump
Hoosier Daddy said:
Perhaps another Reichstag Fire?
Maybe this time to implement the Emergency Health Powers Act?
Possibly with the goal of disarming those in "quarantine".

I have zero trust or faith in those in charge of our government


I have zero faith also. Once this lands on our shores, I fear the worst.
 

1919A6

Inactive
I fear the Lord, as far as this NWO pandemic

is concerned - TPTB have to move and move very, very soon for their time is nearly over.
 

Doomer Doug

Deceased
certainly TPTB will try and exploit the bird flu, just as they do everything else. As I write this in the public library in downtown Portland all the street trash around me is coughing up a storm. There is mass flu infection all over Portland whatever the lying media says. I can see people coughing and hacking whereever I go in public. A much rarer event these days I assure you.

It is big about the Mexican ducks. It is big about the Jakarta cases. This thing just keeps banging along. A lower kill rate equals more infections which equals more dead people.

Everything is on schedule for a global pandemic. Given the corruption and incompetence of government; the squalor and filth of many people in these cesspool countries it is just a matter of time. Just a matter of time.

I think 2005 was the year of Toto, when things were revealed, the incompetence, the stupidity and corruption of the global system. I think 2006 will be the year of results, or consequences and of death on a scale we haven't seen in decades.
 

dissimulo

Membership Revoked
Rex Jackson said:
Just cant help to think this is all BS at times. I hear all about this 'wiping the planet' yet its just laying around. At times it seems to be just a smoke screen for something else.

It is a predictable human reaction to scary circumstances. When there is a big earthquake on the news, we all worry about earthquakes. When there is a tsunami, we all worry about tsunamis. When there was SARS, we all worried about SARS (I lived in Singapore then; that was fun).

Scares sell and the media sells the hell out of whatever keeps the ratings machine going. And, of course, if those in power can swing scares to their advantage, they will.

H5N1 is not BS, but it also may never become a human pandemic. It still pays to be prepped, whether for earthquake, tsunami, hurricane, pandemic, etc. Eventually, some disaster is likely to come along.
 

Kris Gandillon

The Other Curmudgeon
_______________
"That doesn't make sense. Above they say the flu is killing half of all the people who get it then that would mean if 90 million people get it then 45 million people would die not 1.9 million people."

The assumption is that those that have contracted it and died were basically living in 3rd world conditions without the level of medical care that could be provided in the USA.

There have been several interviews with various doctors and agencies etc. on KMOX here in St. Louis over the last couple of months regarding H5N1 and how they come up with these "models" and statistics.

Kris
 

jlee

Inactive
Doomer Doug: probably a lot of that coughing around you is TB (tuberculosis, not Timebomb!), and some of the rest is smoker's cough of some sort or other.
 

bev

Has No Life - Lives on TB
"...downtown Portland all the street trash around me is coughing up a storm."

Doomer Doug - that is really inappropriate. "STREET TRASH?" So I'm STREET TRASH just because I'm coughing up a storm? Come on!

Actually, mine isn't the flu, and it isn't TB. It's a severe sinus infection and it's taken me 3 different antibiotics so far to get to the end of it. Lots of possible reasons for coughs. But, yeah, it's flu season, and it's going to get worse and it won't affect only "street trash."
 
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