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Dogs Arthritis in Dogs - Adequan vs Stem Cell Trial at CUS Vet Hospital
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  1. #1
    Join Date
    May 2001
    Location
    Colorado
    Posts
    3,796

    Arthritis in Dogs - Adequan vs Stem Cell Trial at CUS Vet Hospital

    Opps - should be CSU and not CUS in title.

    Had this on my Pet Alternative Med thread for dog cancer - should have it's own thread.


    My dog is getting these shots now for arthritis. My dog's regular vet said CSU is really BIG on this drug for treating arthritis in dogs - she said it's 'natural' - as the body manufacturers this or similar.

    Adequan is a drug used to treat arthritis in dogs and horses. It is similar to naturally occurring glycosaminoglycan in cartilage. CUS Veterinary Hospital is big on using this for dogs with arthritis. They know it works and have had wonderful results.

    Stem cells are being studied in numerous trials and one at CSU is comparing stem cell infections to Adquan injections. To see if the stem cells work as well or better for treatment of arthritis.The dog owner is not told which his dog is receiving. Improvement is determined by walking the dog on pressure sensitive flooring - this measures the weight placed on each limb as the dog walks. The increase in weight is indicative of improvement in that limb.

    Stem cell therapy for osteoarthritis in dogs.

    Eligibility: Dogs with chronic osteoarthritis (> 6 months duration) of the elbow, knee or hip are eligible for a study investigating the effectiveness of treatment with mesenchymal stem cells (derived from fat tissues of unrelated donor dogs) for relief of joint pain and reduction of joint inflammation. The stem cells will be administered by direct injection into the joint, for a series of 3 treatments at 2-week intervals. The study will require brief sedation for the joint injections and for collection of joint fluid samples. Costs of stem cells will be covered, as will study costs of joint injections and fluid collections. Study eligible dogs must be in good general health and not currently receiving immune suppressive therapy. Treatment with NSAID drugs is allowable during the study, but new drug treatments are not allowed during the 8-week study period. ​*

    Contact:*Dr. Felix Duerr (Felix.Duerr@colostate.edu) ​http://csu-cvmbs.colostate.edu/acade...al-trials.aspx

    A bit more info on Adquan if your dog has arthritis and you don't want to just treat the pain/symptoms (while we await the stem cell results):

    Adequan belongs to a class of drugs called Disease Modifying Osteoarthritis Drugs (DMOAD). It is the only FDA-approved product of its type, and has been clinically shown to help treat arthritis while simultaneously relieving joint pain. Adequan is a prescription medication that can only be dispensed and administered by a licensed veterinarian. That’s because it isn’t just a pill or an ointment, but a treatment requiring injection. When injected directly into your dog’s muscle, Adequan (polysulfated glycosaminoglycan) inhibits bad enzymes that break down cartilage in your dog’s joints.

    Currently, Adequan is only FDA-approved for dogs and horses, though some vets do prescribe it for cats as well. Adequan helps relieve the pain of arthritis by soothing and lubricating the inflamed joint in addition to stimulating joint cartilage repair.*Simply put, it helps your dog’s body heal and prevent further deterioration of your pets’ joints.*[url]https://noahsarkvet.com/the-benefits...pet-arthritis

    The FDA-approved formula that’s never been duplicated.Adequan® Canine (polysulfated glycosaminoglycan) is the only FDA-approved injectable, disease-modifying osteoarthritis drug (DMOAD) that inhibits cartilage loss in the dog’s joint, and may help to:

    Restore joint lubrication

    Relieve inflammation

    Renew the building blocks of healthy cartilage

    Adequan® Canine is recommended for intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.*https://www.adequancanine.com/Adequan for dogs is also known as polysulfated glycosaminoglycan and is approved by the Food and Drug Administration for the treatment of canine osteoarthritis. This drug is defined as a disease modifying osteoarthritis drug (DMOAD) as*it treats the disease while relieving the pain associated with it.

    The drug inhibits the catabolic enzymes that are responsible for eroding the joint. It lubricates the joint and, repairs and binds damaged cartilage. At the same time, it enhances the activity of anabolic enzymes to*stimulate the synthesis of proteins and collagen. When injected into the dog’s muscle, the drug is absorbed by the inflamed joints and provides relief. It starts to work within hours and stays in the affected joints for 3 days
    .https://www.vetinfo.com/treating-dog...njections.html http://<br /> <br /> This is also li...or-Pet-Cancers
    Last edited by Chance; 07-26-2019 at 03:11 PM.
    "Apres la Guerre."

  2. #2
    Join Date
    May 2001
    Location
    Colorado
    Posts
    3,796
    I found that the generic of Adequan, called Ichon, is the same stuff - Polysulfated Glycosaminoglycan - just not FDA approved because of the patent.

    The price is a lot cheaper - but vets confirm it's the same - works the same.

    Just fyi.

    Jazzy is on the twice a week intramuscular injection - for 4 weeks. She has 5 more shots to go.

    Hoping for the best results for her!

    Chance
    "Apres la Guerre."

  3. #3
    Boron deficiency in dogs and supplementation - Vets All Natural

    https://vetsallnatural.com.au/boron-...pplementation/
    Boron is one of the micronutrients required for optimal health and is involved in ... arthritis we see in dogs, and is why Joint Support powder (with added boron) is ...



    Essentiality of boron for healthy bones and joints. - NCBI

    https://www.ncbi.nlm.nih.gov/pubmed/7889887
    by RE Newnham - ‎1994 - ‎Cited by 159 - ‎Related articles
    Since 1963, evidence has accumulated that suggests boron is a safe and effective treatment for some forms of arthritis. ... The preceding data indicate that boron is an essential nutrient for healthy bones and joints, and that further research into the use of boron for the treatment or prevention of arthritis is warranted.

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